Wei Wu PhD , Shijia Zhao PhD , Akshat Banga MBBS , Yash Vardhan Trivedi MBBS , Vineeth S. Dasari MBBS , Parth Munjal MBBS , Rakshita Ramesh Bhat MBBS , Ruben K.A. Tapia-Orihuela MD , Usama M. Oguz MD , Hammad Zafar MBBS , Haritha Darapaneni MBBS , Nikolaos Spilias MD , Jessica Wagner PhD , Stephen Morin PhD , Amanda DeVos BS , Paul A. Iaizzo PhD , Akiko Maehara MD , Evan S. Shlofmitz DO , Ziad A. Ali MD, DPhil , Emmanouil Brilakis MD, PhD , Yiannis S. Chatzizisis MD, PhD
{"title":"高清晰度血管内超声与光学相干断层扫描:管腔大小和斑块形态","authors":"Wei Wu PhD , Shijia Zhao PhD , Akshat Banga MBBS , Yash Vardhan Trivedi MBBS , Vineeth S. Dasari MBBS , Parth Munjal MBBS , Rakshita Ramesh Bhat MBBS , Ruben K.A. Tapia-Orihuela MD , Usama M. Oguz MD , Hammad Zafar MBBS , Haritha Darapaneni MBBS , Nikolaos Spilias MD , Jessica Wagner PhD , Stephen Morin PhD , Amanda DeVos BS , Paul A. Iaizzo PhD , Akiko Maehara MD , Evan S. Shlofmitz DO , Ziad A. Ali MD, DPhil , Emmanouil Brilakis MD, PhD , Yiannis S. Chatzizisis MD, PhD","doi":"10.1016/j.jscai.2024.102520","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Complex percutaneous coronary interventions rely on advanced intravascular imaging techniques, such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT). This study aims to compare the accuracy of the latest high-definition intravascular ultrasound (HD IVUS) and OCT technologies in measuring coronary lumen dimensions and assessing plaque morphology.</div></div><div><h3>Methods</h3><div>We compared HD IVUS and OCT in 8 silicone models using microcomputed tomography as the ground truth. We also compared HD IVUS vs OCT in 12 coronary arteries from 9 patients.</div></div><div><h3>Results</h3><div>In the silicone models, the latest HD IVUS (AVVIGO+, Boston Scientific) system overestimated lumen dimensions compared to microcomputed tomography by +0.06 ± 0.05 mm for mean lumen diameter (MLD). OCT (Ultreon 2.0, Abbott) underestimated lumen dimensions by –0.17 ± 0.06 mm for MLD, with the underestimation being greater for lumen diameters ≥5.0 mm. In clinical cases, the latest HD IVUS (AVVIGO+) system yielded larger lumen dimensions compared to OCT (Ultreon 2.0) by +0.12 ± 0.11 mm for MLD, and the earlier HD IVUS (POLARIS, Boston Scientific) system also showed larger lumen dimensions compared to OCT (AptiVue, Abbott) by +0.26 ± 0.29 mm for MLD. Using OCT as the reference, HD IVUS detected fine wall structures with precision, such as a thin fibrous cap, dissection, and stent struts.</div></div><div><h3>Conclusions</h3><div>The latest HD IVUS (Avvigo+) tends to overestimate lumen size, whereas OCT (Ultreon 2.0) underestimates it. Experimental data suggest HD IVUS provides more accurate lumen assessment, particularly in larger coronary arteries, although both technologies exhibit comparable overall accuracy in the clinical setting.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102520"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"High-Definition Intravascular Ultrasound Versus Optical Coherence Tomography: Lumen Size and Plaque Morphology\",\"authors\":\"Wei Wu PhD , Shijia Zhao PhD , Akshat Banga MBBS , Yash Vardhan Trivedi MBBS , Vineeth S. Dasari MBBS , Parth Munjal MBBS , Rakshita Ramesh Bhat MBBS , Ruben K.A. Tapia-Orihuela MD , Usama M. Oguz MD , Hammad Zafar MBBS , Haritha Darapaneni MBBS , Nikolaos Spilias MD , Jessica Wagner PhD , Stephen Morin PhD , Amanda DeVos BS , Paul A. Iaizzo PhD , Akiko Maehara MD , Evan S. Shlofmitz DO , Ziad A. Ali MD, DPhil , Emmanouil Brilakis MD, PhD , Yiannis S. Chatzizisis MD, PhD\",\"doi\":\"10.1016/j.jscai.2024.102520\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Complex percutaneous coronary interventions rely on advanced intravascular imaging techniques, such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT). This study aims to compare the accuracy of the latest high-definition intravascular ultrasound (HD IVUS) and OCT technologies in measuring coronary lumen dimensions and assessing plaque morphology.</div></div><div><h3>Methods</h3><div>We compared HD IVUS and OCT in 8 silicone models using microcomputed tomography as the ground truth. We also compared HD IVUS vs OCT in 12 coronary arteries from 9 patients.</div></div><div><h3>Results</h3><div>In the silicone models, the latest HD IVUS (AVVIGO+, Boston Scientific) system overestimated lumen dimensions compared to microcomputed tomography by +0.06 ± 0.05 mm for mean lumen diameter (MLD). OCT (Ultreon 2.0, Abbott) underestimated lumen dimensions by –0.17 ± 0.06 mm for MLD, with the underestimation being greater for lumen diameters ≥5.0 mm. In clinical cases, the latest HD IVUS (AVVIGO+) system yielded larger lumen dimensions compared to OCT (Ultreon 2.0) by +0.12 ± 0.11 mm for MLD, and the earlier HD IVUS (POLARIS, Boston Scientific) system also showed larger lumen dimensions compared to OCT (AptiVue, Abbott) by +0.26 ± 0.29 mm for MLD. Using OCT as the reference, HD IVUS detected fine wall structures with precision, such as a thin fibrous cap, dissection, and stent struts.</div></div><div><h3>Conclusions</h3><div>The latest HD IVUS (Avvigo+) tends to overestimate lumen size, whereas OCT (Ultreon 2.0) underestimates it. Experimental data suggest HD IVUS provides more accurate lumen assessment, particularly in larger coronary arteries, although both technologies exhibit comparable overall accuracy in the clinical setting.</div></div>\",\"PeriodicalId\":73990,\"journal\":{\"name\":\"Journal of the Society for Cardiovascular Angiography & Interventions\",\"volume\":\"4 5\",\"pages\":\"Article 102520\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Society for Cardiovascular Angiography & Interventions\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772930324022099\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Society for Cardiovascular Angiography & Interventions","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772930324022099","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
High-Definition Intravascular Ultrasound Versus Optical Coherence Tomography: Lumen Size and Plaque Morphology
Background
Complex percutaneous coronary interventions rely on advanced intravascular imaging techniques, such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT). This study aims to compare the accuracy of the latest high-definition intravascular ultrasound (HD IVUS) and OCT technologies in measuring coronary lumen dimensions and assessing plaque morphology.
Methods
We compared HD IVUS and OCT in 8 silicone models using microcomputed tomography as the ground truth. We also compared HD IVUS vs OCT in 12 coronary arteries from 9 patients.
Results
In the silicone models, the latest HD IVUS (AVVIGO+, Boston Scientific) system overestimated lumen dimensions compared to microcomputed tomography by +0.06 ± 0.05 mm for mean lumen diameter (MLD). OCT (Ultreon 2.0, Abbott) underestimated lumen dimensions by –0.17 ± 0.06 mm for MLD, with the underestimation being greater for lumen diameters ≥5.0 mm. In clinical cases, the latest HD IVUS (AVVIGO+) system yielded larger lumen dimensions compared to OCT (Ultreon 2.0) by +0.12 ± 0.11 mm for MLD, and the earlier HD IVUS (POLARIS, Boston Scientific) system also showed larger lumen dimensions compared to OCT (AptiVue, Abbott) by +0.26 ± 0.29 mm for MLD. Using OCT as the reference, HD IVUS detected fine wall structures with precision, such as a thin fibrous cap, dissection, and stent struts.
Conclusions
The latest HD IVUS (Avvigo+) tends to overestimate lumen size, whereas OCT (Ultreon 2.0) underestimates it. Experimental data suggest HD IVUS provides more accurate lumen assessment, particularly in larger coronary arteries, although both technologies exhibit comparable overall accuracy in the clinical setting.