Journal of the American College of Clinical Pharmacy : JACCP最新文献

{"title":"Restrictions on pharmacist dispensing of mifepristone remain a hard pill to swallow","authors":"Kelli Boyden JD,&nbsp;Randy C. Hatton Pharm.D., FCCP,&nbsp;Catherine M. Lynch M.D.,&nbsp;David B. Brushwood BSPharm, JD","doi":"10.1002/jac5.2034","DOIUrl":"https://doi.org/10.1002/jac5.2034","url":null,"abstract":"<p>This analysis explores the basis for the US Food and Drug Administration (FDA) requiring a Risk Evaluation and Mitigation Strategy (REMS) for mifepristone for the termination of intrauterine pregnancy. Controversies surround mifepristone and its REMS. The safety and efficacy of mifepristone are briefly reviewed with respect to FDA's actions. It is difficult to justify the continued requirement for a REMS for mifepristone by applying the regulatory framework and considering mifepristone's safety record. Drugs with higher risks are on the US market without an FDA-mandated REMS. Canada removed all restrictions on the use of mifepristone for abortion, which has not resulted in patient safety concerns. All pharmacists should be permitted to dispense mifepristone. The continued requirement for a mifepristone REMS in the US appears to be based more on politics rather than evidence.</p>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 11","pages":"1114-1121"},"PeriodicalIF":1.3,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of TikTok social media posts on side effect information for popular weight loss medications","authors":"Jerica Singleton Pharm.D.,&nbsp;Gwendolyn A. Wantuch Pharm.D.","doi":"10.1002/jac5.2035","DOIUrl":"https://doi.org/10.1002/jac5.2035","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The prevalence of overweight and obesity is increasing in America, contributing to various health risks. Glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP) receptor agonists have bloomed in popularity due to their efficacy and United States Food and Drug Administration (FDA) approval for weight loss, igniting popularity on social media. This study focuses on the role of TikTok™ (ByteDance, Haidian, Beijing, China), a popular social media platform, in disseminating understandable and actionable information about the side effects of weight loss medications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study analyzed the top 50 TikTok videos for each of the following hashtags: #ozempicsideeffects, #semaglutidesideeffects, #mounjarosideeffects, and #wegovysideeffects. Videos were evaluated based on their understandability and actionability using the Patient Education Materials Assessment Tool (PEMAT) for audio-visual (AV) products. PEMAT-AV scores and popularity of videos were compared between hashtags utilizing one-way analysis of variance (ANOVA). An alpha of 0.05 was used, with Bonferroni correction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 165 videos were reviewed for PEMAT-AV understandability and actionability scores. The total visibility of the videos reached over 19.4 million views. A majority of the videos were personal experiences (89%), with only 5% being health care education videos. The average understandability and actionability scores for all videos were 43% and 20%, respectfully. The data presented a difference between searched hashtags for both evaluation scores, <i>p</i>-values of &lt;0.001 and 0.093, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>TikTok videos covering weight loss medication side effects have poor understandability and actionability scores. This study highlights the opportunity for more educational videos produced by health care professionals on TikTok, and a potential need for health care organizations and/or colleges of pharmacy to provide education to health care providers on how to create quality content for medication education on social media-based platforms. Further research is needed to evaluate the credibility of content.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 11","pages":"1077-1083"},"PeriodicalIF":1.3,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of hemoglobin A1c control among Medicare advantage patients not meeting non-insulin diabetes medication adherence metric","authors":"Mark Doles Pharm.D.,&nbsp;Benjamin Caswell Pharm.D.,&nbsp;Nicolas Conty Pharm.D.","doi":"10.1002/jac5.2033","DOIUrl":"https://doi.org/10.1002/jac5.2033","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Clinical pharmacists are often tasked with improving medication-related performance metrics such as medication adherence to diabetes medications (MAD). Although the primary goal in patient care is excellent clinical outcomes, it is unknown if poor diabetes disease state control correlates with nonadherence to diabetes medications per the Centers for Medicare and Medicaid Services (CMS) MAD metric specifications. This retrospective study aimed to identify the degree of disease state control in patients identified as nonadherent to their diabetes medications among patients in value-based Medicare Advantage payer-provider reimbursement models and its impact on the clinical pharmacist.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients attributed to a health system-employed primary care provider group from January 1, 2022 to December 31, 2022 and identified as non-adherent (percentage of days covered [PDC] &lt;80%) for non-insulin diabetic medications were included in the study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 370 patients who met criteria for study inclusion, 256 (69%) had a controlled hemoglobin A1C of &lt;7.5%; 305 patients also had a previous A1c available in the electronic medical record. Of those, 260 (85%) had an A1C that had improved or was unchanged between the two most recent readings. One hundred sixty (43%) patients had a reason listed for gaps within refill history including verbal dose change, adverse reaction, manufacturer-supplied medications, fills from Veteran's Affairs pharmacy, provider samples, or nondiabetes diagnosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>A large percentage of patients identified as non-adherent had a high degree of disease state control suggesting an issue with the measurement of adherence rather than a true reflection of patients' adherence with prescribed drug regimens. Strategies to improve diabetes medication adherence based on PDC will likely need to look beyond disease state control.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 11","pages":"1094-1098"},"PeriodicalIF":1.3,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A tale of two bills: Lessons learned in expanding pharmacist-led HIV pre-exposure and post-exposure prophylaxis","authors":"Jennifer Cocohoba Pharm.D., MAS,&nbsp;Jerika Lam Pharm.D.,&nbsp;Maria Lopez Pharm.D.,&nbsp;Betty J. Dong Pharm.D.","doi":"10.1002/jac5.2027","DOIUrl":"https://doi.org/10.1002/jac5.2027","url":null,"abstract":"","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 10","pages":"982-983"},"PeriodicalIF":1.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142429598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Part II: Recorded webcast: Vaping”","authors":"","doi":"10.1002/jac5.2029","DOIUrl":"https://doi.org/10.1002/jac5.2029","url":null,"abstract":"<p>Shelton CM. Part II: recorded webcast: vaping. <i>J Am Coll Clin Pharm</i>. 2024;7(9):971–5.</p><p>The self-assessment questions are incorrect, and not the assessment tied to this learning activity. The correct 12 questions are available upon purchase of the product.</p><p>We apologize for this error.</p>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 11","pages":"1137"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jac5.2029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “2024 ACCP Virtual Poster Symposium May 21–22, 2024”","authors":"","doi":"10.1002/jac5.2030","DOIUrl":"https://doi.org/10.1002/jac5.2030","url":null,"abstract":"<p>2024 ACCP Virtual Poster Symposium May 21–22, 2024. <i>J. Am. Coll. Clin. Pharm</i>. 2024;7:682–737.</p><p>Due to an oversight, the following abstract was inadvertently omitted from the published 2024 ACCP Virtual Poster Symposium abstracts. We regret the omission and are publishing the abstract below.</p><p><b>VPS Advances in International Clinical Pharmacy, Education and Training</b></p><p><b>The Use of Virtual Simulated Patients in Clinical Pharmacy Education: A Computer-Based Simulation.</b></p><p>Yuanhui Hu, Master, Yuyao Pei, Doctor, Feng Yu, B.Sc(Med), M.Sc, PhD, Ruoxin Huang, Master and <i>Yufen Zheng, Doctor</i></p><p><i>Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China</i></p><p><b>Abstract Text:</b></p><p><b>Service or Program:</b> Development of virtual simulated patient teaching software for pharmaceutical care skills training and its application to clinical pharmacy students at China Pharmaceutical University.</p><p><b>Justification/Documentation:</b> Students visited the virtual simulation lab to undergo training with virtual simulated patient cases, which involved caring for patients afflicted with various diseases: cancer pain, osteoporosis, acne, asthma, diabetes, and other diseases. Each simulation patient training session necessitated students to undertake the following tasks: (1) review the patient's basic information; (2) gather essential patient data; (3) evaluate the patient's condition and devise a monitoring plan, as well as provide patient education, information collection and patient education need to be implemented with virtual patients. Students reported that this experience aided in enhancing their information-gathering abilities, reinforcing their understanding of course material, and applying it in real-world scenarios. They also noted that it contributed to their improved performance on the final assessment.</p><p><b>Adaptability:</b> The adaptability of utilizing virtual simulated patients in clinical pharmacy education stems from their versatility and ability to replicate diverse clinical scenarios. Virtual simulated patients can be programmed to mimic various medical conditions, enabling students to practice clinical decision-making and patient care in a controlled environment. Consequently, they can be effectively and sustainably incorporated into the teaching of clinical pharmacy.</p><p><b>Significance:</b> A virtual simulation patient teaching software can assist students in enhancing their knowledge and practical skills, while also aiding teachers in reducing lesson preparation time and enhancing teaching efficiency. This addresses the gap in virtual simulation teaching tools for pharmacy practice skills in China.</p><p>We apologize for this error.</p>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 11","pages":"1138"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jac5.2030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pascal's uncertainty principle: Managing drug–drug interactions when the risks are unclear","authors":"Philip D. Hansten Pharm.D.,&nbsp;Ainhoa Gomez-Lumbreras M.D., Ph.D.,&nbsp;Lorenzo Villa-Zapata Ph.D.,&nbsp;Daniel C. Malone Ph.D.","doi":"10.1002/jac5.2031","DOIUrl":"https://doi.org/10.1002/jac5.2031","url":null,"abstract":"<p>Therapeutic decision-making (TDM) often occurs under conditions of scientific uncertainty, including decisions on how to manage the majority of drug–drug interactions (DDIs). The existence of many DDIs is not firmly established, and there is an unfortunate tendency to make decisions based on the binary assessment of whether or not a particular DDI is real, rather than taking a more probabilistic and holistic approach to TDM. There also seems to be an undue fear of making a Type I error (assuming the DDI is real when it is not) while ignoring the often much greater risk of a Type II error (assuming the DDI is not real, when it is). Thus, a more rational TDM process for such DDIs is needed. In his famous “Wager,” philosopher-mathematician Blaise Pascal made a probabilistic argument for believing in God. Instead of considering probability in isolation, Pascal <i>linked</i> the probability of God's existence with the severity of the outcome (an eternity in Hell for non-believers) and also added a third factor—the ease with which the risk can be avoided. We propose a novel paradigm for TDM that uses all three of Pascal's steps: probability, severity, and avoidability. We present several specific DDI examples to demonstrate how Pascal's Uncertainty Principle can help pharmacists make clinical management decisions for these DDIs. We suggest that this process be called “Pascal's Uncertainty Principle” rather than “Pascal's Wager,” because it can be used to make rational decisions in the presence of uncertainty in many non-theological situations. This process reinforces the value of philosophical training for pharmacy students.</p>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 12","pages":"1197-1206"},"PeriodicalIF":1.3,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jac5.2031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the impact of pharmacist counseling on patient satisfaction and willingness to pay: A study in the Pakistan health care context","authors":"Asma Ghulam Mustafa MPhil,&nbsp;Adeel Aslam Ph.D.","doi":"10.1002/jac5.2032","DOIUrl":"https://doi.org/10.1002/jac5.2032","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Patient-centered pharmacist counseling enhances health care experiences by fostering understanding and trust. This study aimed to understand patient satisfaction levels and their propensity to pay for pharmacist counseling services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study is a cross-sectional survey that was carried out in Lahore, Pakistan. The study was conducted from May to July 2023, utilizing the Patient Satisfaction Feedback (PSF) questionnaire as the primary tool for data collection in various community pharmacies. The data was collated from 300 completed surveys and subsequently analyzed using descriptive statistical techniques in IBM SPSS software (Version 22). The analysis provided valuable insights into the influence of counseling services on patients' viewpoints.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the study, a diverse sample of patients demonstrated a notably positive reception of pharmacist counseling. The majority of the respondents had a positive response towards easy access to this service, with 76.7% reporting no difficulty. Furthermore, 49.7% expressed complete satisfaction in obtaining the knowledge they required, while 43.3% indicated they received this knowledge to some extent. Prominent values were observed, including 57.3% expressing high satisfaction levels, and 71.3% demonstrating readiness to pay for it. Notably, gender-related differences were observed, with females displaying particularly strong positive attitudes towards counseling services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In conclusion, this study revealed significant patient satisfaction with pharmacist counseling services, with over half of the participants expressing contentment. Moreover, despite the country's lower health care spending, a substantial portion of patients expressed a willingness to pay for this service, highlighting the potential for establishing pharmaceutical care services with a distinctive role within Pakistan's health care sector.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 12","pages":"1188-1196"},"PeriodicalIF":1.3,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Development and application of quality measures of clinical pharmacist services provided in inpatient/acute care settings”","authors":"","doi":"10.1002/jac5.2028","DOIUrl":"https://doi.org/10.1002/jac5.2028","url":null,"abstract":"<p>Acquisto NM, Beavers CJ, Bolesta S, Buckley MS, Dobbins KF, Finch CK, et al. Development and application of quality measures ofclinical pharmacist services provided in inpatient/acute care settings. J Am Coll Clin Pharm. 2021;4(12):1601-1617. doi:10.1002/jac5.1559.</p><p>We apologize for this error.</p>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 11","pages":"1135-1136"},"PeriodicalIF":1.3,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jac5.2028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serving as a professional association board member: Benefits to leaders and their employers","authors":"Brian L. Erstad Pharm.D., FCCP,&nbsp;Judith Jacobi Pharm.D., FCCP,&nbsp;William A. Kehoe Pharm.D., M.A., FCCP,&nbsp;Suzanne A. Nesbit Pharm.D., FCCP,&nbsp;Terry L. Seaton Pharm.D., FCCP","doi":"10.1002/jac5.2026","DOIUrl":"https://doi.org/10.1002/jac5.2026","url":null,"abstract":"<p>This commentary, written by past presidents of the American College of Clinical Pharmacy, highlights the benefits of serving in leadership roles within professional associations to the leaders themselves, their employers, their colleagues, and the broader profession. Fostering the development of leaders is a necessary step to advance pharmacy's future. Leaders benefit not only from the reinvigoration and personal growth associated with their service effort but also from the further development of skills such as collaboration and consensus-building, written and oral communication, critical thinking, leadership, and time management. The honing of these skills has benefits at the leader's workplace. Colleagues in businesses outside health care view this type of leadership experience as external training to develop and refine organizational communication and leadership skills and better prepare their employees for the future. The leader also learns best practices and new perspectives that, when shared locally, can energize the employer organization. Beyond the benefits to the leader and the leader's employer, there are holistic benefits of association service to the profession and interprofessional teams. With this in mind, we suggest that employers welcome opportunities to have their coworkers serve in elected or appointed positions within professional associations.</p>","PeriodicalId":73966,"journal":{"name":"Journal of the American College of Clinical Pharmacy : JACCP","volume":"7 10","pages":"1068-1070"},"PeriodicalIF":1.3,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142430164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}