Journal of rural medicine : JRM最新文献_第5页

Gait analysis using three-dimensional motion and ground reaction force systems in patients with hemiplegia treated with botulinum toxin type A in ankle plantar flexors. 利用三维运动和地面反作用力系统对踝关节跖屈肌接受A型肉毒毒素治疗的偏瘫患者进行步态分析。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2024-006

Masato Murakami, Tsuneo Okada

{"title":"Gait analysis using three-dimensional motion and ground reaction force systems in patients with hemiplegia treated with botulinum toxin type A in ankle plantar flexors.","authors":"Masato Murakami, Tsuneo Okada","doi":"10.2185/jrm.2024-006","DOIUrl":"10.2185/jrm.2024-006","url":null,"abstract":"Objective: The efficacy of botulinum toxin type A (BoNT-A) injection on spasticity has usually been measured using the range of motion (ROM) of joints and Modified Ashworth Scale (MAS); however, they only evaluate muscle tone at rest. We objectively analyzed the gait of three patients with hemiplegia using three-dimensional motion analysis and ground reaction force (GRF) systems to evaluate muscle tone during gait. Materials and Methods: We measured passive ankle dorsiflexion ROM with knee extension and the MAS score for clinical evaluation, and gait speed, stride length, single-leg support phase during the gait cycle, joint angle, joint moment, and GRFs for kinematic evaluation before and one month after BoNT-A injection. Results: All patients showed an increase in ankle dorsiflexion ROM, improvement in MAS score, and increase in stride length. Case 1 showed an increase in gait speed, prolongation of the single-leg support phase, increase in hip extension angle and moment, and improvement in the vertical and anterior-posterior components of the GRFs. Case 2 showed an increase in gait speed, improvement in double knee action, increase in ankle plantar flexion moment, and improvement in propulsion in the progressive component of the GRFs. Case 3 exhibited a laterally directed force in the GRFs. Conclusion: We evaluated the effects of BoNT-A injections in three patients with hemiplegia using three-dimensional motion analysis and GRFs. The results of the gait analysis clarified the improvements and problems in hemiplegic gait and enabled objective explanations for patients.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"174-180"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Service provision conditions for foreign residents in municipalities in Japan. 日本市镇为外国居民提供服务的条件。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2023-043

Mayumi Ohnishi, Megumi Kisu, Mika Nishihara, Yasuhide Nakamura, Rieko Nakao, Satoko Kosaka, Ryoko Kawasaki

{"title":"Service provision conditions for foreign residents in municipalities in Japan.","authors":"Mayumi Ohnishi, Megumi Kisu, Mika Nishihara, Yasuhide Nakamura, Rieko Nakao, Satoko Kosaka, Ryoko Kawasaki","doi":"10.2185/jrm.2023-043","DOIUrl":"10.2185/jrm.2023-043","url":null,"abstract":"Objectives: This study examined the actual conditions of service provision to foreign residents (FRs) addressing prevention of lifestyle-related diseases (LRDs) and disaster preparedness/disaster responses (DPRs) in Japanese municipalities. Materials and Methods: A cross-sectional study was performed using a self-administered questionnaire with representatives of public health nurses in each municipality in Japan from December 2021 to January 2022. Results: Services considering FRs are more likely to be implemented in cities than in towns, and in municipalities where FRs account for ≥2.2% of the population (proportion of FRs in the Japanese population at the time of the study) than in those with fewer FRs. Cities have larger populations and greater financial resources than towns. Factors associated with the implementation of services and measures necessary for providing services to FRs were the classification of the municipality as a city, a high percentage of FRs, and large variation in corresponding nationalities/countries of origin. Conclusions: Cross-disciplinary efforts and collaborations need to be strengthened to share available resources within local governments and experiences in providing services for FRs in other divisions/sections, rather than considering only how to provide services for FRs in the public health division/section.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"141-149"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perspectives of persons in charge regarding support for the health and daily lives of female technical intern trainees who migrate to Japan: a qualitative study. 负责人对移居日本的女性技能实习生的健康和日常生活支持的看法：一项定性研究。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2023-039

Aya Shinohara, Noriko Kuwano, Yoshimitsu Shinagawa, Ryoko Kawasaki, Mayumi Ohnishi

{"title":"Perspectives of persons in charge regarding support for the health and daily lives of female technical intern trainees who migrate to Japan: a qualitative study.","authors":"Aya Shinohara, Noriko Kuwano, Yoshimitsu Shinagawa, Ryoko Kawasaki, Mayumi Ohnishi","doi":"10.2185/jrm.2023-039","DOIUrl":"10.2185/jrm.2023-039","url":null,"abstract":"Objectives: Migrant technical intern trainees who migrate to Japan have become essential to the Japanese labour force, especially in rural areas. Persons in charge of supervising organisations and training coordinators both support the trainees' health and daily lives during their stay in Japan. This support is significant for trainees as it helps them access and interact with Japanese society. This study explored the perspectives of persons in charge of female technical trainees regarding support for the latter's health and daily lives. Materials and Methods: Semi-structured interviews were conducted with 14 persons in charge of female technical trainees, followed by a thematic analysis of the interview data to extract key themes. Results: Four primary themes emerged: fostered beliefs and roles, cultural considerations and health support, language considerations, and concerns about female trainees in relationships. These considerations and support developed solely through experience of persons in charge of female trainees. Additionally, those in charge expressed concerns about trainees being involved in a relationship. However, no specific measures, such as providing female trainees with information, have been taken. Conclusion: Persons in charge of female technical intern trainees need to be provided opportunities to learn about cultural considerations and providing health support for their trainees. Furthermore, the cooperation of health professionals with supervising organisations and training facilities is essential to promote the healthy lives of technical intern trainees. These insights can contribute to the development of an integrated community-based approach to support the health and daily lives of female trainees.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"131-140"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alocasia odora poisoning due to calcium oxalate needle crystals in Japan. 日本草酸钙针状结晶引起的 Alocasia odora 中毒。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2024-001

Youichi Yanagawa, Hiroki Nagasawa

{"title":"Alocasia odora poisoning due to calcium oxalate needle crystals in Japan.","authors":"Youichi Yanagawa, Hiroki Nagasawa","doi":"10.2185/jrm.2024-001","DOIUrl":"10.2185/jrm.2024-001","url":null,"abstract":"Objective: To elucidate the actual circumstances of damage caused by Japanese Alocasia (A) odora. Materials and Methods: We investigated cases in Japan from our own hospital in the eastern part of Shizuoka Prefecture as well as published reports. Results: A. dorais found in western Japan, and plants of the Alocasia genus are cultivated often. A. odora is frequently associated with food poisoning because its aboveground parts resemble those of Satoimo (Colocasia esculenta). Moreover, A. odora contains insoluble calcium oxalate crystals, which cause poisoning symptoms, such as oral pain, nausea, vomiting, and laryngeal edema, resulting in near asphyxia, diarrhea following shock, and skin dermatitis. Calcium oxalate crystals are abundant in Araceae family plants, and cases of health damage owing to the accidental ingestion of Araceae plants have been reported worldwide. Conclusion: Due to the strong irritation felt in the mouth upon contact with the plant, it is advisable to immediately spit out the plant and rinse the mouth. In addition to drug administration, ensuring a secure airway may be necessary if there is a risk of asphyxiation.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"126-130"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of reduced daily magnesium oxide doses on laxative effect: a single-center retrospective study. 减少每日氧化镁剂量对通便效果的影响：一项单中心回顾性研究。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2023-038

Norio Watanabe, Akira Itano, Motozumi Ando, Masami Kawahara

{"title":"Effect of reduced daily magnesium oxide doses on laxative effect: a single-center retrospective study.","authors":"Norio Watanabe, Akira Itano, Motozumi Ando, Masami Kawahara","doi":"10.2185/jrm.2023-038","DOIUrl":"10.2185/jrm.2023-038","url":null,"abstract":"Objective: To investigate the laxative effect of reducing the number of daily doses of magnesium oxide (MgO), while maintaining the total daily dose of MgO in patients with good bowel movements. Patients and Methods: The retrospective analysis involved 11 patients with regular bowel movements who were prescribed MgO for constipation upon admission to a nursing care facility accompanied by home visits by a pharmacist. This investigation was conducted before and after reducing the number of daily doses from three to two, or from two to one, over a two-week period. Results: The number of bowel movements was 7.6 ± 3.4 and 6.6 ± 4.0 times for two weeks before and after the change in dosage frequency, respectively. The difference was not statistically significant (P=0.09). The Bristol Stool Form Scale was 3.9 ± 0.9 and 4.0 ± 0.9 two weeks before and after the change, respectively, which was not significant (P=0.93). Two weeks after the change, the MgO regimen remained unchanged and no on-demand laxatives were administered. Conclusions: The results suggest that reducing the number of daily doses of MgO does not affect its laxative action.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"192-195"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stretching exercises for growing children: evaluation of obesity, flexibility, pain and injury of musculoskeletal organs before and one year later. 成长中儿童的伸展运动：对肥胖、柔韧性、疼痛和肌肉骨骼器官损伤的评估（一年前和一年后）。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2023-051

Maiko Ohtaka, Masayo Saito, Yukiko Ito

{"title":"Stretching exercises for growing children: evaluation of obesity, flexibility, pain and injury of musculoskeletal organs before and one year later.","authors":"Maiko Ohtaka, Masayo Saito, Yukiko Ito","doi":"10.2185/jrm.2023-051","DOIUrl":"10.2185/jrm.2023-051","url":null,"abstract":"Objective: Rapid bone development in growing children causes excessive tension in the lower extremities' muscles and tendons, leading to reduced flexibility and increased musculoskeletal disorder risk. Further, lack of exercise causes obesity. Therefore, we created a stretching exercise protocol to prevent musculoskeletal disorders in elementary school (middle and upper grades) children during their growth period, when rapid bone development begins. Patients and Methods: We examined the effects on pain, injury, and flexibility. Fifty-three (boys: 34, girls: 19) students in grades 3-5 (ages 9-11) performed the stretching exercises at school thrice a week for one year, and we compared the results before and a year after the intervention. Results: A three-minute stretching exercise routine achieved an intensity of 4.6-4.9 metabolic equivalents (METs; equivalent to brisk walking). Obesity (P=1.000), flexibility problems (inability to bend forward [P=0.754] or squat problems [P=1.000]), bone/joint pain (P=1.000), and injury (P=1.000) did not significantly increase. Conclusion: Stretching exercises during the growth period may help prevent childhood musculoskeletal disorders, obesity, and flexibility loss.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"150-157"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between sTREM2, an immune biomarker of microglial activation, and frontal lobe function in community-dwelling older adults: a cross-sectional study. 社区老年人的小胶质细胞活化免疫生物标志物 sTREM2 与额叶功能之间的关系：一项横断面研究。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2024-018

Ryuzo Orihashi, Yoshiomi Imamura, Yoshito Mizoguchi

{"title":"Association between sTREM2, an immune biomarker of microglial activation, and frontal lobe function in community-dwelling older adults: a cross-sectional study.","authors":"Ryuzo Orihashi, Yoshiomi Imamura, Yoshito Mizoguchi","doi":"10.2185/jrm.2024-018","DOIUrl":"10.2185/jrm.2024-018","url":null,"abstract":"Objective: Identifying the peripheral biomarkers related to the prevention or modification of unhealthy mental conditions in older adults is extremely beneficial. This study aimed to evaluate the serum levels of soluble triggering receptor expressed on myeloid cells 2 (sTREM2), a soluble form of an innate immune receptor expressed on microglia, in older adults living in a rural community, and their association with cognitive function. Materials and Methods: This survey was conducted between November 2016 and September 2017 in Kurokawa-cho, Imari, Saga Prefecture, Japan, among people aged ≥65 years. Blood samples were collected from the participants for serum sTREM2 level analysis using a peptide enzyme immunoassay. The participants underwent cognitive function assessments, including the Mini-Mental State Examination, Clinical Dementia Rating, and Frontal Assessment Battery. Therefore, we examined the association between serum sTREM2 levels and cognitive function. Results: Of the 95 participants, 25 were men and 70 were women with a mean age 78.24 ± 3.85 years and 77.96 ± 5.52 years, respectively. Serum sTREM2 levels were negatively associated with Frontal Assessment Battery scores, even after adjusting for age, sex, years of education, and serum high-sensitivity C-reactive protein levels. Conclusion: Serum sTREM2 levels may be associated with frontal lobe function in adults aged ≥65 years.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"186-191"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histological differences in cartilage layer growth at various tendon and ligament insertions in rabbits. 兔子不同肌腱和韧带插入处软骨层生长的组织学差异。

Journal of rural medicine : JRM Pub Date : 2024-07-01 DOI: 10.2185/jrm.2024-009

Hirotaka Mutsuzaki, Hiromi Nakajima

{"title":"Histological differences in cartilage layer growth at various tendon and ligament insertions in rabbits.","authors":"Hirotaka Mutsuzaki, Hiromi Nakajima","doi":"10.2185/jrm.2024-009","DOIUrl":"10.2185/jrm.2024-009","url":null,"abstract":"Objectives: Histological differences in cartilage layer growth in Achilles tendon (AT), quadriceps tendon (QT), patellar tendon (PT), and anterior cruciate ligament (ACL) insertion are unclear. Therefore, this study aimed to investigate the differences in cartilage layer growth in AT, QT, PT, and ACL insertions. Materials and Methods: Forty-eight male Japanese white rabbits were used. Six animals were euthanized at different stages (day 1 and 1, 2, 4, 6, 8, 12, and 24 weeks). Safranin O-stained glycosaminoglycan (GAG) production area, chondrocyte count, and insertion width were investigated. Results: A two-way analysis of variance (ANOVA) revealed a significant difference in the main effects of time and insertion for all parameters. In addition, the time × insertion interaction was significant. Multiple comparisons showed a significant difference between the ACL insertion and all other variables; however, the GAG production area was not significantly different for the QT, PT, and AT insertions. AT insertions were significantly different from all other groups; however, the number of chondrocytes and insertion width were not significantly different for ACL, QT, and PT insertions. Conclusion: Cartilage layer growth differed between the AT, QT, PT, and ACL insertions. The differences between the insertions may also be due to the differences in their structures, locations, and mechanical environments.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"19 3","pages":"181-185"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11222623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and sociodemographic determinants of common mental disorders (CMDs) symptoms in a rural adult population of Haryana, North India 印度北部哈里亚纳邦农村成年人常见精神障碍（CMDs）症状的发生率和社会人口决定因素

Journal of rural medicine : JRM Pub Date : 2024-04-01 DOI: 10.2185/jrm.2023-013

MD. Abu Bashar, A. Mehra, Arun Kumar Aggarwal

{"title":"Prevalence and sociodemographic determinants of common mental disorders (CMDs) symptoms in a rural adult population of Haryana, North India","authors":"MD. Abu Bashar, A. Mehra, Arun Kumar Aggarwal","doi":"10.2185/jrm.2023-013","DOIUrl":"https://doi.org/10.2185/jrm.2023-013","url":null,"abstract":"Objectives: Common mental disorders (CMDs), including depression, anxiety, and somatoform disorders, affect all stages of life and impact individuals, families, and communities. This study aimed to determine the magnitude of CMDs and their sociodemographic determinants in the adult population of a rural block in North India. Material and Methods: A cross-sectional, quantitative, community-based study was conducted among adult residents of a rural block in Haryana, North India, using a multistage random sampling technique. The Hindi version of the General Health Questionnaire (GHQ-12), a well-validated tool, was used to screen participants for CMDs. Scores of 4 or above denoted the presence of CMDs. Bivariate analyses were performed to determine the associations between CMDs and sociodemographic characteristics. Results: Of the 180 residents selected for the study, most were women (60.0%) and aged between 31 and 50 years (52.3%). The prevalence of CMDs symptoms in the study population was 20.0%. The presence of CMDs symptoms was significantly higher among those who were aged 60 years or older [OR=12.33, 95% CI 3.21–47.38], widowed, divorced or separated [OR=7.50, 95% CI 1.09–51.52], illiterate [OR= 6.25, 95% CI 2.84–13.77], had monthly family income below 10,000 INR [OR=3.33, 95% CI 1.54–7.20], had any chronic physical illness [OR=8.28, 95% CI 3.70–18.56] and had a family history of any psychiatric illness [OR=5.56, 95% CI 1.52–19.42]. Conclusion: The burden of CMDs was quite high among adults in rural North India. The presence of CMDs was closely associated with sociodemographic characteristics. Primary care and community-based settings need to screen for, diagnose, and manage CMDs to address this growing problem.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"68 8","pages":"49 - 56"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in coagulation factor XIII activity during resuscitation for hemorrhagic shock 失血性休克复苏期间凝血因子 XIII 活性的变化

Journal of rural medicine : JRM Pub Date : 2024-04-01 DOI: 10.2185/jrm.2023-028

Yusuke Yamada, T. Abe, Rina Tanohata, Hidenobu Ochiai

{"title":"Changes in coagulation factor XIII activity during resuscitation for hemorrhagic shock","authors":"Yusuke Yamada, T. Abe, Rina Tanohata, Hidenobu Ochiai","doi":"10.2185/jrm.2023-028","DOIUrl":"https://doi.org/10.2185/jrm.2023-028","url":null,"abstract":"Objective Little is known about the coagulation activity of factor XIII (FXIII) during resuscitation for hemorrhagic shock and the effects of plasma transfusions. We performed a single-center observational study to evaluate the changes in FXIII activity during resuscitation for hemorrhagic shock. Patient and Methods Twenty-three adult patients with hemorrhagic shock were enrolled in this study. Blood samples were drawn upon arrival (T1), at the time of hemostasis completion (T2), and on day 2 (T3). Baseline and changes in FXIII activity and the proportion of patients with adequate levels of FXIII activity (FXIII activity >70%) were evaluated. The effects of plasma transfusion on these parameters were also investigated. Results At T1, the median (interquartile range) FXIII activity was 53% (47–85%), which did not increase (T1 vs. T3: 53% [47–85%] vs. 63% [52–70%], P=0.8766). The proportion of patients with adequate FXIII activity decreased throughout the resuscitation period (T1, T2, and T3: 30, 34, and 21%, respectively). Plasma transfusion did not affect FXIII activity (T1 vs. T2, 66.4% [23.4] vs. 70.0% [16.2%], P=0.3956; T2 vs. T3, 72.0% [19.5] vs. 63.5% [8.6%], P=0.1161) or the proportion of adequate levels of FXIII activity at 44% at T2 and 27% at T3. Conclusion FXIII activity is low during the early phase of a hemorrhagic shock. Even with plasma transfusion, FXIII levels were not adequately maintained throughout resuscitation.","PeriodicalId":73939,"journal":{"name":"Journal of rural medicine : JRM","volume":"64 ","pages":"76 - 82"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0