Thijs Van Meulenbroek, Arnoud E A Conijn, Ivan P J Huijnen, Raoul H H Engelbert, Jeanine A Verbunt
{"title":"Multidisciplinary Treatment for Hypermobile Adolescents with Chronic Musculoskeletal Pain.","authors":"Thijs Van Meulenbroek, Arnoud E A Conijn, Ivan P J Huijnen, Raoul H H Engelbert, Jeanine A Verbunt","doi":"10.2340/20030711-1000033","DOIUrl":"https://doi.org/10.2340/20030711-1000033","url":null,"abstract":"<p><strong>Background: </strong>To determine whether adolescents with generalized hypermobility spectrum disorder/ hypermobile Ehlers-Danlos syndrome (G-HSD/ hEDS) show changes in the level of disability, physical functioning, perceived harmfulness and pain intensity after completing multidisciplinary rehabilitation treatment.</p><p><strong>Methods: </strong>Pre-test post-test design. Fourteen adolescents with G-HSD/hEDS participated. The multidisciplinary rehabilitation treatment consisted of a combination of physical training and exposure <i>in vivo</i>. Physical training aims to improve aerobic capacity, muscle strength and propriocepsis for compensating hypermobility. Exposure <i>in vivo</i> aims to decrease disability and pain-related fear. Pre- and post-treatment assessments were conducted to assess the level of disability, physical functioning (motor performance, muscle strength and physical activity level), perceived harmfulness and pain intensity.</p><p><strong>Results: </strong>After completing multidisciplinary rehabilitation treatment, the adolescents showed a significant and clinically relevant improvement (improvement of 67%, <i>p</i><0.01) in functional disability. Furthermore, significant improvements were found in motor performance (<i>p</i> < 0.01), muscle strength (<i>p</i> < 0.05), perceived harmfulness (<i>p</i> < 0.01) and pain intensity (<i>p</i> <0.01) after completing multidisciplinary rehabilitation treatment.</p><p><strong>Conclusion: </strong>Multidisciplinary rehabilitation treatment leads to a significantly and clinically relevant improvement in the level of disability for adolescents with G-HSD/hEDS. Positive effects were also found in physical functioning, perceived harmfulness and pain intensity. Although the results of this multidisciplinary rehabilitation treatment for adolescents with G-HSD/hEDS are promising, further study is needed to confirm these findings in a randomized design.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/85/JRMCC-3-1000033.PMC8008726.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38897095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brent M Peterson, Daniel Y K Shackelford, Jessica M Brown, Alyse P Brennecke, Reid Hayward
{"title":"Effects of Aerobic and Flexibility Training on Physiological and Psychosocial Function in a Patient with Anaplastic Oligodendroglioma: A Case Report.","authors":"Brent M Peterson, Daniel Y K Shackelford, Jessica M Brown, Alyse P Brennecke, Reid Hayward","doi":"10.2340/20030711-1000032","DOIUrl":"https://doi.org/10.2340/20030711-1000032","url":null,"abstract":"<p><strong>Objective: </strong>Diagnoses of anaplastic oligodendrogliomas are rare. For cancer rehabilitation practitioners, anaplastic oligodendroglioma may impact on the development and maintenance of prescriptive exercise. Exercise interventions for healthy individuals and cancer patients have been shown to increase functional capacity, psychosocial functioning, and aspects of cognitive function. However, there is a lack of research into exercise interventions among patients with anaplastic oligodendroglioma. This case report of a patient with anaplastic oligodendroglioma, measures the effects of aerobic and flexibility training on physiological, psychosocial, and cognitive functioning.</p><p><strong>Patient: </strong>A 44-year old woman diagnosed with class III anaplastic oligodendroglioma with 1p19q genetic co-deletion underwent left-frontal craniotomy, chemotherapy, and radiation treatment. Comprehensive physical, psychosocial, and cognitive assessments were completed before and after a 36-session exercise intervention.</p><p><strong>Results: </strong>Following the intervention improvements were observed in 9 of the 14 physiological measures. Fatigue decreased by 20% and quality of life increased by almost 70%. Improvements were also observed in 6 of the 12 cognitive assessment variables.</p><p><strong>Conclusion: </strong>The 36 sessions of aerobic and flexibility training were well-tolerated by the subject. The results demonstrate the feasibility and importance of aerobic and flexibility training for the attenuation of cancer-related decrements in physiological and psychosocial variables in patients with anaplastic oligodendroglioma. The effects on cognitive function were uncertain.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/83/JRMCC-3-1000032.PMC8008718.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38897094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rudi Frankinouille, Greetje Vanhoutte, Gaëtane Stassijns, Carmen De Coster, Ella Roelant, Marika Rasschaert, Jan Gielen, Sevilay Altintas, Marc Peeters
{"title":"EVALUATION OF A SUPERVISED PHYSICAL ACTIVITY PROGRAMME FOR CANCER SURVIVORS: FROM TREATMENT TO TRIATHLON.","authors":"Rudi Frankinouille, Greetje Vanhoutte, Gaëtane Stassijns, Carmen De Coster, Ella Roelant, Marika Rasschaert, Jan Gielen, Sevilay Altintas, Marc Peeters","doi":"10.2340/20030711-1000030","DOIUrl":"https://doi.org/10.2340/20030711-1000030","url":null,"abstract":"<p><strong>Objective: </strong>It is recommended that cancer survivors incorporate physical activity into their daily lives after in-hospital rehabilitation. However, there is a lack of training programmes focusing on the specific needs of cancer survivors. TriaGO! - an 8-month intervention study of aerobic endurance training for cancer survivors - was therefore examined. The training programme aims to meet the participants' physical needs and provide socio-emotional support, in the form of an exercise programme that challenges participants to aim to compete in an Olympic- distance triathlon (1,000 m swimming, 45 km cycling, 10 km running) after 8 months' of training.</p><p><strong>Methods: </strong>The TriaGO! training programme was provided to in-hospital rehabilitated cancer survivors (<i>n</i> = 12). Each patient invited a healthy friend or family member to train with them (a so called buddy (<i>n</i> = 12)). The 8-month programme involves supervised training sessions, combining cycling, swimming and running, which progress in frequency, duration and intensity. Physical health was measured at the start, 4 and 8 months, using objective parameters of aerobic fitness, muscular fitness and body composition.</p><p><strong>Results: </strong>A total of 22 out of 24 participants successfully completed the training programme and the triathlon. Both the cancer survivors and their buddies showed significant improvements in physical health. Cancer survivors showed improvements in aerobic fitness, as increases in VO<sub>2</sub>max and VO<sub>2</sub>peak of 5.5 ml.kg<sup>-1</sup>.min<sup>-1</sup> and 0.26 ml.min<sup>-1</sup> respectively (<i>p</i> <0.0001). Buddies underwent similar significant increases; 5.39 ml.kg<sup>-1</sup>.min<sup>-1</sup> and 0.18 ml.min<sup>-1</sup>, respectively.</p><p><strong>Conclusion: </strong>The TriaGO! training programme introduces the concept of supervised endurance training for cancer survivors. Through measurement of ob-jective parameters, this study demonstrated that significant physical reconditioning is possible in cancer survivors. A supervised programme would be recommended for all cancer patients after in-hospital treatment, in order to facilitate the transition to incorporation of physical activity into daily life.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/4d/JRMCC-3-1000030.PMC8008719.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38897093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paola Perini, Margherita Caristi, Elisabetta Mondin, Maria Rosaria Matarrese, Giovanni Cortese, Alessandro Giustini, Ilaria Cannella, Alessia Pinzello, Paolo Fogar
{"title":"Traumatic Brain Injury Caused by Work Accidents: How can Occupational and Vocational Recovery be Achieved?","authors":"Paola Perini, Margherita Caristi, Elisabetta Mondin, Maria Rosaria Matarrese, Giovanni Cortese, Alessandro Giustini, Ilaria Cannella, Alessia Pinzello, Paolo Fogar","doi":"10.2340/20030711-1000031","DOIUrl":"10.2340/20030711-1000031","url":null,"abstract":"<p><p>Issues connected with the reintegration of individuals affected by severe brain injury are numerous and complex. Extensive data indicate the effectiveness of treatments based on an holistic approach, which integrates medical interventions with social programmes and offers continuity, leading to the rapid achievement of independent living outcomes and return to work. In Italy, extensive resources are available for the clinical and rehabilitation management of individuals affected by traumatic brain injury in the acute and post-acute phase, but there are only a few organized services to support the reintegration phase. This paper describes a model created via a 2-year collaboration between the National Institute for Insurance against Accidents at Work (INAIL) in Rome and the National Federation of Traumatic Brain Injury Associations (FNATC). The combined effort of these organizations led to the development of an Italian Model of Vocational Rehabilitation (IMoVR), which was exportable to all 20 Italian Regions. Due to the experience gained by a few avant-garde teams, IMoVR was used to pioneer an approach characterized by structured phases and actions aimed at designing high-quality interventions, and at monitoring their long-term effectiveness. These teams comprised experts in different areas, including: forensic doctors, social workers, administrative managers of INAIL, neuropsychologists, psychotherapists, educators working in associations registered with FNATC, all of whom are members of a service network that had already activated small individual vocational projects. In total, the collaboration comprised 42 pro-fessionals working in 7 Italian cities: Ancona, Arezzo, Ferrara, Milano, Pordenone, Rimini and Vicenza.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/ac/JRMCC-3-1000031.PMC8008731.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Spasticity and Below-Level Neuropathic Pain Related to Spinal Cord Injury Level and Damage to the Lower Spinal Segments.","authors":"Bengt Skoog, Karl-Erik Jakobsson","doi":"10.2340/20030711-1000039","DOIUrl":"https://doi.org/10.2340/20030711-1000039","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate spasticity and below-level spinal cord injury neuropathic pain after spinal cord injury in patients with, or without, damage to the lumbar spinal cord and roots.</p><p><strong>Design/patients: </strong>Chart review of 269 patients with spinal cord injury from segments C1 to T11.</p><p><strong>Methods: </strong>Patients were interviewed concerning leg spasticity and below-level spinal cord injury neuropathic pain in the lower trunk and legs. Damage to the lumbar spinal cord and roots was inferred where there was radiological evidence of a vertebral fracture, spinal stenosis or the narrowing of spinal foramina of a vertebra from thoracic 11 to lumbar 5, or; magnetic resonance imaging showing evidence of damage to the lumbar spinal cord and roots.</p><p><strong>Results: </strong>Among 161 patients without damage to the lumbar spinal cord and roots, 87% of those with cervical spinal cord injury experienced spasticity, compared with 85% with thoracic spinal cord injury. The corresponding figures for patients in whom damage to the lumbar spinal cord and roots was present were 57% and 52%, respectively. Below-level spinal cord injury neuropathic pain was not associated with damage to the lumbar spinal cord and roots. In those patients with no damage to the lumbar spinal cord and roots, regression showed that neither outcome was significantly associated with the level of spinal cord injury.</p><p><strong>Conclusion: </strong>The lack of segmental dependency for spinal cord injury and spasticity suggests mechanisms restricted mainly to the lumbar spinal cord. For below-level spinal cord injury neuropathic pain, additional mechanisms, other than lesions of the spino-thalamic tract, must be considered.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/0a/JRMCC-3-1000039.PMC8008733.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38897019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serial Analysis of Cardiopulmonary Fitness and Echocardiography in Patients with Fabry Disease Undergoing Enzyme Replacement Therapy.","authors":"Sheng-Hui Tuan, Pao-Chin Chiu, I-Hsiu Liou, Wen-Hsien Lu, Hung-Ya Huang, Shin-Yi Wu, Guan-Bo Chen, Ko-Long Lin","doi":"10.2340/20030711-1000028","DOIUrl":"https://doi.org/10.2340/20030711-1000028","url":null,"abstract":"<p><strong>Objective: </strong>Fabry disease, a rare X-linked disorder, can lead to exercise intolerance. In Taiwan, the cardiac variant of Fabry disease has a significantly higher prevalence than the classic variant. The cardiac variant of Fabry disease primarily involves the heart. Enzyme replacement therapy has been used to treat both variants. We aimed to study the impact of enzyme replacement therapy on exercise and cardiac structures between the classic (CL-FD) and cardiac variant (CV-FD) Fabry disease.</p><p><strong>Design and methods: </strong>Retrospective analysis of 2 groups of patients with Fabry disease (5 patients with the classic variant and 5 with the cardiac variant), who were undergoing enzyme replacement therapy. Patients were assessed annually for 3 years using symptom-limited cycle ergometry and echocardiography.</p><p><strong>Results: </strong>Subjects were 5 women, mean age 53 (standard deviation (SD) 14.05) years with CL-FD Fabry disease, and 5 men, mean age 65 (SD 2.35) years with CV-FD. The percentage of peak oxygen consumption to predicted value for all included patients was significantly lower (78.78% (SD 12.72)) than 100%. Annual serial measurement showed that peak metabolic equivalent and percentage of peak oxygen consumptiondecreased significantly over a period of 3 years in patients with CV-FD (<i>p</i> = 0.002, and <i>p</i> =0.004, respectively), but not in those with CL-FD. There were no significant changes in annual serial measurements of left ventricular mass or interventricular septal thickness in patients with either variant of Fabry disease over a period of 3 years.</p><p><strong>Conclusion: </strong>Peak exercise capacity of the patients with Fabry disease was lower than that of normal peers. Peak exercise capacity decreased over time.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/c9/JRMCC-3-1000028.PMC8008727.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason Hsu, Kirk Kee, Andrew Perkins, Alex Gorelik, Jeremy Goldin, Louisa Ng
{"title":"Effectiveness of a Novel Sleep Clinical Pathway in an Inpatient Musculoskeletal Rehabilitation Cohort: A Pilot Randomized Controlled Trial.","authors":"Jason Hsu, Kirk Kee, Andrew Perkins, Alex Gorelik, Jeremy Goldin, Louisa Ng","doi":"10.2340/20030711-1000029","DOIUrl":"https://doi.org/10.2340/20030711-1000029","url":null,"abstract":"<p><strong>Objective: </strong>Sleep disturbance in hospital is common. This pilot randomized controlled trial assessed a sleep clinical pathway compared with standard care in improving sleep quality, engagement in therapy and length of stay in musculoskeletal inpatient rehabilitation.</p><p><strong>Methods: </strong>Participants (<i>n</i> = 51) were randomized to standard care (\"control\", <i>n</i> =29) or sleep clinical pathway (\"intervention\", <i>n</i> = 22). Outcome measures included: Pittsburgh Sleep Quality Index (PSQI), Hopkins Rehabilitation Engagement Rating Scale (HRERS), Fatigue Severity Scale (FSS), Patient Satisfaction with Sleep Scale, and actigraphy. Assessment time-points were at admission and before discharge from rehabilitation.</p><p><strong>Results: </strong>No significant differences were found between groups for any outcome measure. As a cohort (<i>n</i> = 51), there were significant improvements from admission to discharge in sleep quality (PSQI (-2.31; 95% confidence interval (95% CI) -3.33 to -1.30; <i>p</i> <0.001)], fatigue (FSS (-8.75; 95% CI -13.15 to -4.34; <i>p</i> <0.001)], engagement with therapy (HRERS-Physiotherapists (+1.37; 95% CI 0.51-3.17; <i>p</i> =0.037), HRERS-Occupational Therapists (+1.84; 95% CI 0.089-2.65; <i>p</i> = 0.008)), and satisfaction with sleep (+0.824; 95% CI 0.35-1.30; <i>p</i> = 0.001). Actigraphy findings were equivocal.</p><p><strong>Conclusion: </strong>The sleep clinical pathway did not improve sleep quality compared with standard care. Larger studies and studies with alternate methodology such as \"cluster randomization\" are needed.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/1d/JRMCC-3-1000029.PMC8008738.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katarina Skough Vreede, Lisbet Broman, Kristian Borg
{"title":"Is Intervention to Prevent Falls Necessary in Prior Polio Patients?","authors":"Katarina Skough Vreede, Lisbet Broman, Kristian Borg","doi":"10.2340/20030711-1000023","DOIUrl":"https://doi.org/10.2340/20030711-1000023","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether intervention to prevent falls is necessary in prior polio patients, by identifying the frequency, circumstances and consequences of falls among patients in Sweden with prior polio.</p><p><strong>Subjects: </strong>Patients with prior polio diagnosis.</p><p><strong>Methods: </strong>A falls history questionnaire was completed by patients with prior polio visiting the outpatient clinic at the Department of Rehabilitation Medicine, Danderyd University Hospital, Stock-holm, Sweden, or participating in group activities organized by the patient organization.</p><p><strong>Results: </strong>A total of 80 patients answered the questionnaire; 32 men and 48 women. Eighty-one percent (<i>n</i> = 63/77) of respondents walked outdoors, but rarely more than 1 km, or only inside and near the house. Three-quarters of patients had fallen one or more times over the past year and one-quarter of patients had fallen 5 times or more. The falls often occurred during daytime in an environment known to the patient. Sixty-nine percent (<i>n</i> = 40/58) of respondents had been injured due to falling during the past year. The most common injuries were minor injuries.</p><p><strong>Conclusion: </strong>Falls are common in patients in Sweden with prior polio. Interventions to prevent falls in people with prior polio are therefore clinically relevant.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/bd/JRMCC-3-1000023.PMC8008737.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analgesia by Sacral Surface Electrical Stimulation for Primary Dysmenorrhoea.","authors":"Mieko Yokozuka, Mayumi Nagai, Rieko Katsura, Kayoko Kenmyo","doi":"10.2340/20030711-1000027","DOIUrl":"https://doi.org/10.2340/20030711-1000027","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of analgesia by sacral surface electrical stimulation on lower abdominal pain in women with primary dysmenorrhoea.</p><p><strong>Design: </strong>Explorative study.</p><p><strong>Participants: </strong>Eleven female university students, who regularly experience difficulty in their university work due to menstrual pain, or who use analgesics for more than one day each month, were recruited.</p><p><strong>Methods: </strong>Sacral surface electrical stimulation, 5 Hz for 15 min, was performed after the onset of menstruation. Electrodes were placed on the skin, directly above the second and fourth sacral foramina. Visual analogue scale and degree of pain (calculated by using a low current to assess pain) were determined before and after electrical stimulation.</p><p><strong>Results: </strong>Visual analogue scale score and degree of pain decreased significantly immediately after electrical stimulation (<i>p</i> < 0.001). A correlation was observed between visual analogue scale score and degree of pain before and after electrical stimulation (r=0.516, <i>p</i> <0.001). No side-effects were observed in any participant.</p><p><strong>Conclusion: </strong>Sacral surface electrical stimulation may provide immediate pain relief in women with dysmenorrhoea and lower abdominal pain.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/08/JRMCC-3-1000027.PMC8008724.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Goffin, Virginie Nguyen, Michéle Fostier, Thierry Gustin, Thierry Deltombe
{"title":"Serotonin Syndrome Mimicking Intrathecal Baclofen Withdrawal in a Patient with Hereditary Spastic Paraparesis.","authors":"Nicolas Goffin, Virginie Nguyen, Michéle Fostier, Thierry Gustin, Thierry Deltombe","doi":"10.2340/20030711-1000026","DOIUrl":"https://doi.org/10.2340/20030711-1000026","url":null,"abstract":"<p><strong>Context: </strong>Serotonin syndrome is a drug-induced condition related to an increased level of serotonin in the brain, which may induce neuromuscular, autonomic and mental symptoms.</p><p><strong>Case report: </strong>A 40-year-old woman with hereditary spastic paraparesis (Strumpell-Lorrain disease) with an implanted intrathecal baclofen pump for severe spasticity. Two days after starting a medication known to inhibit serotonin re-uptake (paroxetine), she developed a sudden increase in lower limb spasticity with continuous spasms, fever, tachycardia and hypertension. Intrathecal baclofen withdrawal was excluded, confirming serotonin syndrome.</p><p><strong>Conclusion: </strong>Medications that inhibit serotonin reuptake may induce serotonin syndrome, resulting in increased spasticity in patients with spinal cord lesions, and should be prescribed with caution.</p>","PeriodicalId":73929,"journal":{"name":"Journal of rehabilitation medicine. Clinical communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/ea/JRMCC-3-1000026.PMC8008723.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38903510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}