Journal of pediatrics, perinatology and child health最新文献

筛选
英文 中文
De Novo Crohn's Disease Diagnosed in the Setting of Acute SARS-Cov-2 Infection Requiring Escalation of Infliximab Therapy Guided by Personalized Pharmacokinetics. 在急性 SARS-Cov-2 感染时诊断出新克罗恩病,需要在个性化药代动力学指导下升级英夫利西单抗疗法
Journal of pediatrics, perinatology and child health Pub Date : 2024-01-01 Epub Date: 2024-01-12 DOI: 10.26502/jppch.74050172
Martin Varea Romo, Kishor Acharya, Nathan R Shelman, Phillip Minar, Lee A Denson, Samir Softic
{"title":"De Novo Crohn's Disease Diagnosed in the Setting of Acute SARS-Cov-2 Infection Requiring Escalation of Infliximab Therapy Guided by Personalized Pharmacokinetics.","authors":"Martin Varea Romo, Kishor Acharya, Nathan R Shelman, Phillip Minar, Lee A Denson, Samir Softic","doi":"10.26502/jppch.74050172","DOIUrl":"https://doi.org/10.26502/jppch.74050172","url":null,"abstract":"<p><p>Here, we describe a 7-year-old girl who was diagnosed with an early-onset Crohn's disease in the setting of COVID-19 illness. Her disease process responded poorly to standard infliximab dosing, necessitating repeat hospitalizations and red blood cell transfusions. Remission was subsequently induced using a personalized infliximab pharmacokinetic profile based on therapeutic drug monitoring. While the initial data does not support a link, several case reports suggest an association between COVID-19 illness and de-novo development of IBD, especially in young female patients. We report, to our knowledge, the youngest patient who developed early-onset Crohn's disease in the setting of concomitant SARS-CoV-2 infection.</p>","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"8 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11042678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational dermatoses in health care personnel using PPE during the COVID pandemic. COVID大流行期间使用个人防护装备的卫生保健人员的职业性皮肤病
Journal of pediatrics, perinatology and child health Pub Date : 2023-07-16 DOI: 10.1101/2023.07.13.23292421
Dinesh P Asati, K. Baheti, Maninder Kaur, S. Patra, Kritika Singhal Singhal
{"title":"Occupational dermatoses in health care personnel using PPE during the COVID pandemic.","authors":"Dinesh P Asati, K. Baheti, Maninder Kaur, S. Patra, Kritika Singhal Singhal","doi":"10.1101/2023.07.13.23292421","DOIUrl":"https://doi.org/10.1101/2023.07.13.23292421","url":null,"abstract":"Background: A sudden surge of occupation-associated dermatoses among the healthcare workers (HCWs) serving COVID-19 patients have been witnessed recently due to increased usage of PPE (PPE) kits and increased frequency of hygiene practices, with a significant impact on their quality of life and compromised efficacy at work. Hence, this study was conducted to measure the prevalence of occupational dermatoses among HCWs serving Covid-19 patients using PPE kits and hygiene practices and their impact on quality of life. Methods: HCWs of all cadres were screened for occupation-associated dermatoses. Cases with occupational dermatosis were evaluated further regarding the use of a PPE kit, and DLQI was calculated. Results: 19% of HCWs had dermatoses associated with PPE and hygiene practices. Hands were most affected, followed by the face, nasal bridge, and facial skin in contact with goggles. 48% had Mathias score >/= 4. Most cases had reported some impact on their quality of life. A significant association could be established between frequency of hand washing >/= 10 times/day with hand dermatitis (p=0.000). Conclusion: The use of PPE has significantly raised cases of occupational dermatosis among HCWs. Repeated hand washing and hand sanitizer use has increased the incidence of hand dermatitis.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42365215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Digital Dashboard for Visual Representation of Child Health Information: Results of A Mixed Methods Study on Usability and Feasibility of A New CHILD-Profile 儿童健康信息可视化表示的数字仪表板:一种新的儿童概况可用性和可行性混合方法研究的结果
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050142
Miriam Weijers, Jonne Van der Zwet, N. Boumans, F. Feron, Caroline H.G. Bastiaenen
{"title":"A Digital Dashboard for Visual Representation of Child Health Information: Results of A Mixed Methods Study on Usability and Feasibility of A New CHILD-Profile","authors":"Miriam Weijers, Jonne Van der Zwet, N. Boumans, F. Feron, Caroline H.G. Bastiaenen","doi":"10.26502/jppch.74050142","DOIUrl":"https://doi.org/10.26502/jppch.74050142","url":null,"abstract":"Feasibility","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69350508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Malignant Pleural Effusion as an Initial Manifestation of Acute Lymphoblastic Leukemia: A Rare Case Report 双侧恶性胸腔积液作为急性淋巴细胞白血病的初始表现:一个罕见的病例报告
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050148
Gajjar Jay Daxay, Vyakhya ., Ajeta Vijaykumar Gupta, Bhagwan Sahai Sharma, Susheel kumar saini, Madhur Sarthalia, Ajay kumar saini
{"title":"Bilateral Malignant Pleural Effusion as an Initial Manifestation of Acute Lymphoblastic Leukemia: A Rare Case Report","authors":"Gajjar Jay Daxay, Vyakhya ., Ajeta Vijaykumar Gupta, Bhagwan Sahai Sharma, Susheel kumar saini, Madhur Sarthalia, Ajay kumar saini","doi":"10.26502/jppch.74050148","DOIUrl":"https://doi.org/10.26502/jppch.74050148","url":null,"abstract":"Exudative pleural effusion in children is mainly caused by bacterial infections. Leukemia rarely presents as pleural effusion as the first manifestation of the disease process. Bilateral malignant pleural effusion as an initial manifestation that leads to the diagnosis of an underlying acute lymphoblastic leukemia is a rare event. Most commonly pleural effusion is seen as complication in solid tumors such as the lung, lymphomas, carcinomas of the breast and gastrointestinal tract.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69350612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive End-Expiratory Pressure During Helmet Ventilation in Critically Ill Bronchiolitis: A Multicenter Randomized Clinical Trial 危重毛细支气管炎头盔通气期间呼气末正压:一项多中心随机临床试验
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050153
Emanuele Rossetti MD, PhD, Zaccaria Ricci, MD, Daniele Bonacina, MD, Cristina Giugni MD, Ezio Bonanomi MD
{"title":"Positive End-Expiratory Pressure During Helmet Ventilation in Critically Ill Bronchiolitis: A Multicenter Randomized Clinical Trial","authors":"Emanuele Rossetti MD, PhD, Zaccaria Ricci, MD, Daniele Bonacina, MD, Cristina Giugni MD, Ezio Bonanomi MD","doi":"10.26502/jppch.74050153","DOIUrl":"https://doi.org/10.26502/jppch.74050153","url":null,"abstract":"Emanuele Rossetti MD, PhD1*, Zaccaria Ricci, MD2, Daniele Bonacina, MD3, Cristina Giugni MD2 , Ezio Bonanomi MD3, Marina Franci MN1, Marta Ciofi degli Atti MD4, Manuela L’Erario MD2, Daniela Perrotta MD1, Corrado Cecchetti MD, PhD1, Linda Appierto MD1, Luigi Dei Giudici MD1, Alessandro Germani MD1, Francesco Polisca MD1, Francesca Tortora MD1, Ivano Farinelli MD1, Fabrizio Chiusolo MD1, Paola Serio MD2, Roberto Bianchi MD1, Sergio G. Picardo MD1 on behalf of the SARNePI (Italian Society for Pediatric and Neonatal Anaesthesia and Intensive Care).","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69350663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between Serum Testosterone Level and Erythrocytosis in Adolescent Males- A Cross-Sectional Study 青少年男性血清睾酮水平与红细胞增多症的相关性横断面研究
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050137
Ariel Ben, Abu Arisha Rana, Bechor Ariel Tal, Yana Moshe, Leibzon Maor, Ben-Acon Michael, Sharon Nechama
{"title":"Correlation between Serum Testosterone Level and Erythrocytosis in Adolescent Males- A Cross-Sectional Study","authors":"Ariel Ben, Abu Arisha Rana, Bechor Ariel Tal, Yana Moshe, Leibzon Maor, Ben-Acon Michael, Sharon Nechama","doi":"10.26502/jppch.74050137","DOIUrl":"https://doi.org/10.26502/jppch.74050137","url":null,"abstract":"Background: Androgens and testosterone can induce erythrocytosis in several mechanisms. Adolescent males often present to primary clinics with an elevated Red Blood Cell values without Hemoglobin abnormalities. We investigated the correlation between serum testosterone levels and red blood cell values. Methods: 91 adolescents who were referred to the Emergency department were included in the trial, for which a complete blood count and serum testosterone were obtained, along with assessing Tanner score. Patients were divided into two groups with high and low red blood cell count. Mann -Whitney U test was performed to compare Serum testosterone level and Tanner score between the groups. Pearson’s correlation coefficient was calculated to determine the correlation between red blood cell count and Testosterone levels. Results: Testosterone levels was higher in the erythrocytosis group 14.05 (SD 5.53) vs non erythrocytosis group 11.94 (SD 7.38) although it did not meet statistical significance (p-value = 0.168). There is a weak positive correlation (Pearson’s R = 0.146) between testosterone and erythrocyte levels. Conclusion: In healthy adolescent males, whose serum testosterone levels are within normal range we observed erythrocytosis in 22% of patients. Testosterone levels was positively correlated with","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69350451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Failure to Adjust CT Scanners to Pediatric Settings is a Major Cause of Unnecessary Radiation Exposure to Children 未能将CT扫描仪调整为儿童设置是儿童不必要辐射暴露的主要原因
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050166
Jianna J. Lin, Jeremy Zhang, Lucille Anzia, Laura L. Hayes
{"title":"Failure to Adjust CT Scanners to Pediatric Settings is a Major Cause of Unnecessary Radiation Exposure to Children","authors":"Jianna J. Lin, Jeremy Zhang, Lucille Anzia, Laura L. Hayes","doi":"10.26502/jppch.74050166","DOIUrl":"https://doi.org/10.26502/jppch.74050166","url":null,"abstract":"CT scans are an indispensable tool for evaluating head injuries and neurological symptoms, yet they are the leading contributor to medical radiation exposure in the United States. High levels of such exposure pose significant health risks for children, whose developing bodies are less resilient to radiation injury. Here we review mean radiation dose (Total Exam DLP) and CTDlvol from head CT scans of 149 cases to assess for factors thought to be potential contributors to excess radiation exposure. Such factors included scan indication (trauma, shunts, other head complaints), number of repeat scans, and the type of facility the scan was performed (adult vs. pediatric). Analyses revealed that among scans performed to evaluate head trauma or routine indications (e.g. headache, vomiting focal neurologic deficits), the mean radiation dose a administered was significantly higher in adults hospitals when compared to pediatric hospitals. Findings highlight the importance of ensuring appropriate dose settings to increase the safety of CT scans for children. Based on our results identifying suboptimal scanner settings as a fundamental cause of excess radiation exposure, the evidence supports adjusting protocols to appropriate settings as the most effective method of reducing excess radiation exposure to children receiving head CT scans.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135060165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic of Sepsis in a Congolese Pediatric Emergency Service Using PSOFA Score: A Prospective Study 使用PSOFA评分预测刚果儿科急诊败血症的预后:一项前瞻性研究
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050162
Jacques Balekelayi wa Balekelayi, Valérie Bolingo Bola, Stéphanie Mikalo Mbambi, Joseph Mabiala Bodi, Victoire Audray Bikoumou
{"title":"Prognostic of Sepsis in a Congolese Pediatric Emergency Service Using PSOFA Score: A Prospective Study","authors":"Jacques Balekelayi wa Balekelayi, Valérie Bolingo Bola, Stéphanie Mikalo Mbambi, Joseph Mabiala Bodi, Victoire Audray Bikoumou","doi":"10.26502/jppch.74050162","DOIUrl":"https://doi.org/10.26502/jppch.74050162","url":null,"abstract":"Prognostic","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135445107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe Intraventricular Hemorrhage is Associated with Lung Injury in Preterm Infants on Mechanical Ventilation. 使用机械通气的早产儿严重脑室内出血与肺损伤有关。
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 Epub Date: 2023-11-29 DOI: 10.26502/jppch.74050168
Monika Piatek, Elie G Abu Jawdeh, Peter Giannone, Brandon Miller, Aric Schadler, Mina Hanna
{"title":"Severe Intraventricular Hemorrhage is Associated with Lung Injury in Preterm Infants on Mechanical Ventilation.","authors":"Monika Piatek, Elie G Abu Jawdeh, Peter Giannone, Brandon Miller, Aric Schadler, Mina Hanna","doi":"10.26502/jppch.74050168","DOIUrl":"10.26502/jppch.74050168","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to better understand the relationship between intraventricular hemorrhage and the risk of development of early lung disease in extremely low birth weight infants. We hypothesize that infants with severe intraventricular hemorrhage have higher respiratory severity scores than infants with mild/no intraventricular hemorrhage within the first 7 days of life.</p><p><strong>Methods: </strong>This was a single center retrospective study conducted on subjects born between 01/01/2018 and 06/30/2021 at the University of Kentucky Children's Hospital NICU. We enrolled preterm infants with gestational age of less than 30 weeks and birth weight of less than 1000 grams who were placed on mechanical ventilation on admission.</p><p><strong>Results: </strong>We found a clinically significant increasing trend of respiratory severity scores within the first week of life in the group of infants with severe intraventricular hemorrhage.</p><p><strong>Conclusion: </strong>This study is first to show that severe intraventricular hemorrhage is associated with higher respiratory severity scores predicting early lung injury in the extremely low birth weight infants placed on a mechanical ventilator within the first 7 days of life.</p>","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"7 4","pages":"229-234"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10785697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Childhood Hepatitis A Infection with Bilateral Pleural Effusion Acalculous Cholecystitis and Massive Ascites 儿童甲型肝炎感染合并双侧胸腔积液、无结石性胆囊炎及大量腹水一例
Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050140
Ranjum, Naina Nanda, Nitya Sehgal, Susheel kumar saini, Vinay Gahlot, Keerthana Anigani, Tushar Jagat, Ajay kumar saini, S. Kumari
{"title":"A Rare Case of Childhood Hepatitis A Infection with Bilateral Pleural Effusion Acalculous Cholecystitis and Massive Ascites","authors":"Ranjum, Naina Nanda, Nitya Sehgal, Susheel kumar saini, Vinay Gahlot, Keerthana Anigani, Tushar Jagat, Ajay kumar saini, S. Kumari","doi":"10.26502/jppch.74050140","DOIUrl":"https://doi.org/10.26502/jppch.74050140","url":null,"abstract":"Hepatitis A virus infections are mostly asymptomatic or mildly symptomatic in pediatric population. Generally this disease has a benign course and resolves spontaneously. However, intrahepatic and extrahepatic manifestations can complicate typical course of acute hepatitis A in children. Pleural effusion, acalculous cholecystitis and ascites are extremely rare extrahepatic complications. Pleural effusion or ascites does not change the prognosis or require any invasive treatment usually. We report a case of 8 years old boy presented with both pleural effusion and gross ascites accompanying hepatitis A infection. Diagnosis was done using serological testing and imaging studies. He was treated with supportive management only with full recovery after 4 weeks.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69350501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信