Journal of pediatrics, perinatology and child health最新文献

Impact of Maternal Ultra-Processed Food Consumption and Preterm Birth on the Development of Metabolic Disorders in Offspring. 母体超加工食品消费和早产对后代代谢紊乱发育的影响。

Journal of pediatrics, perinatology and child health Pub Date : 2025-01-01 Epub Date: 2025-04-28 DOI: 10.26502/jppch.74050214

Gauri Gurumurthy, Devendra K Agrawal

{"title":"Impact of Maternal Ultra-Processed Food Consumption and Preterm Birth on the Development of Metabolic Disorders in Offspring.","authors":"Gauri Gurumurthy, Devendra K Agrawal","doi":"10.26502/jppch.74050214","DOIUrl":"10.26502/jppch.74050214","url":null,"abstract":"This review examines the growing concern regarding the relationship between maternal ultra-processed food (UPF) consumption, preterm birth, and the subsequent development of metabolic disorders in offspring. Ultra-processed foods have become increasingly prevalent in global diets, coinciding with rising rates of metabolic diseases. Concurrently, preterm birth remains a significant public health concern affecting 5-18% of births worldwide. Here, we critically reviewed the current evidence regarding how maternal UPF consumption affects fetal development and how preterm birth disrupts metabolic programming. Furthermore, the information is presented on the potential synergistic effects when both factors are present. The mechanisms underlying these associations, including fetal malnutrition, inflammation, and hormonal dysregulation, are analyzed. Research suggests that maternal UPF consumption and preterm birth independently contribute to altered metabolic health in offspring, with potential compounding effects when both factors are present. This review highlights the public health implications of these findings and identifies areas requiring further research to better understand the complex interplay between maternal diet, preterm birth, and long-term metabolic health outcomes in offspring.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"9 2","pages":"68-84"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurodevelopmental Risk in HIV-Exposed Uninfected Children: Call for Developmental Surveillance. 暴露于hiv的未感染儿童的神经发育风险：呼吁进行发育监测。

Journal of pediatrics, perinatology and child health Pub Date : 2025-01-01 Epub Date: 2025-10-16 DOI: 10.26502/jppch.74050227

Aliyah Williams, Devendra K Agrawal

{"title":"Neurodevelopmental Risk in HIV-Exposed Uninfected Children: Call for Developmental Surveillance.","authors":"Aliyah Williams, Devendra K Agrawal","doi":"10.26502/jppch.74050227","DOIUrl":"10.26502/jppch.74050227","url":null,"abstract":"As global efforts to prevent mother-to-child transmission of HIV have expanded, the population of children born HIV-exposed, uninfected (HEU) has grown substantially. HEU children face distinctive biological and environmental exposures that may place them at risk for neurodevelopmental challenges. This narrative review synthesizes evidence from the past decade on the neurodevelopmental outcomes of HEU children, including cognitive, motor, and behavioral differences observed across multiple international cohorts. It explores contributing factors such as maternal immune alterations, residual viremia during pregnancy, antiretroviral drug exposure, and postnatal growth impairments. These exposures have been linked to measurable developmental delays in infancy and early childhood, with some effects persisting into school age. Despite these risks, developmental monitoring is not routinely included in the care of HEU children. This review underscores the need to integrate neurodevelopmental surveillance into pediatric HIV-exposed care, optimize anti-retroviral therapy regimens with consideration of fetal outcomes, and support caregiver- and community-based interventions that promote healthy development. Addressing the developmental needs of HEU children is critical to improving long-term outcomes and ensuring this growing population is not left behind.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"9 4","pages":"184-189"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145866789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

De Novo Crohn's Disease Diagnosed in the Setting of Acute SARS-Cov-2 Infection Requiring Escalation of Infliximab Therapy Guided by Personalized Pharmacokinetics. 在急性 SARS-Cov-2 感染时诊断出新克罗恩病，需要在个性化药代动力学指导下升级英夫利西单抗疗法

Journal of pediatrics, perinatology and child health Pub Date : 2024-01-01 Epub Date: 2024-01-12 DOI: 10.26502/jppch.74050172

Martin Varea Romo, Kishor Acharya, Nathan R Shelman, Phillip Minar, Lee A Denson, Samir Softic

引用次数: 0

Occupational dermatoses in health care personnel using PPE during the COVID pandemic. COVID大流行期间使用个人防护装备的卫生保健人员的职业性皮肤病

Journal of pediatrics, perinatology and child health Pub Date : 2023-07-16 DOI: 10.1101/2023.07.13.23292421

Dinesh P Asati, K. Baheti, Maninder Kaur, S. Patra, Kritika Singhal Singhal

{"title":"Occupational dermatoses in health care personnel using PPE during the COVID pandemic.","authors":"Dinesh P Asati, K. Baheti, Maninder Kaur, S. Patra, Kritika Singhal Singhal","doi":"10.1101/2023.07.13.23292421","DOIUrl":"https://doi.org/10.1101/2023.07.13.23292421","url":null,"abstract":"Background: A sudden surge of occupation-associated dermatoses among the healthcare workers (HCWs) serving COVID-19 patients have been witnessed recently due to increased usage of PPE (PPE) kits and increased frequency of hygiene practices, with a significant impact on their quality of life and compromised efficacy at work. Hence, this study was conducted to measure the prevalence of occupational dermatoses among HCWs serving Covid-19 patients using PPE kits and hygiene practices and their impact on quality of life. Methods: HCWs of all cadres were screened for occupation-associated dermatoses. Cases with occupational dermatosis were evaluated further regarding the use of a PPE kit, and DLQI was calculated. Results: 19% of HCWs had dermatoses associated with PPE and hygiene practices. Hands were most affected, followed by the face, nasal bridge, and facial skin in contact with goggles. 48% had Mathias score >/= 4. Most cases had reported some impact on their quality of life. A significant association could be established between frequency of hand washing >/= 10 times/day with hand dermatitis (p=0.000). Conclusion: The use of PPE has significantly raised cases of occupational dermatosis among HCWs. Repeated hand washing and hand sanitizer use has increased the incidence of hand dermatitis.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42365215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Digital Dashboard for Visual Representation of Child Health Information: Results of A Mixed Methods Study on Usability and Feasibility of A New CHILD-Profile 儿童健康信息可视化表示的数字仪表板:一种新的儿童概况可用性和可行性混合方法研究的结果

Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050142

Miriam Weijers, Jonne Van der Zwet, N. Boumans, F. Feron, Caroline H.G. Bastiaenen

引用次数: 0

Bilateral Malignant Pleural Effusion as an Initial Manifestation of Acute Lymphoblastic Leukemia: A Rare Case Report 双侧恶性胸腔积液作为急性淋巴细胞白血病的初始表现:一个罕见的病例报告

Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050148

Gajjar Jay Daxay, Vyakhya ., Ajeta Vijaykumar Gupta, Bhagwan Sahai Sharma, Susheel kumar saini, Madhur Sarthalia, Ajay kumar saini

引用次数: 0

Positive End-Expiratory Pressure During Helmet Ventilation in Critically Ill Bronchiolitis: A Multicenter Randomized Clinical Trial 危重毛细支气管炎头盔通气期间呼气末正压:一项多中心随机临床试验

Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050153

Emanuele Rossetti MD, PhD, Zaccaria Ricci, MD, Daniele Bonacina, MD, Cristina Giugni MD, Ezio Bonanomi MD

引用次数: 0

Correlation between Serum Testosterone Level and Erythrocytosis in Adolescent Males- A Cross-Sectional Study 青少年男性血清睾酮水平与红细胞增多症的相关性横断面研究

Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050137

Ariel Ben, Abu Arisha Rana, Bechor Ariel Tal, Yana Moshe, Leibzon Maor, Ben-Acon Michael, Sharon Nechama

{"title":"Correlation between Serum Testosterone Level and Erythrocytosis in Adolescent Males- A Cross-Sectional Study","authors":"Ariel Ben, Abu Arisha Rana, Bechor Ariel Tal, Yana Moshe, Leibzon Maor, Ben-Acon Michael, Sharon Nechama","doi":"10.26502/jppch.74050137","DOIUrl":"https://doi.org/10.26502/jppch.74050137","url":null,"abstract":"Background: Androgens and testosterone can induce erythrocytosis in several mechanisms. Adolescent males often present to primary clinics with an elevated Red Blood Cell values without Hemoglobin abnormalities. We investigated the correlation between serum testosterone levels and red blood cell values. Methods: 91 adolescents who were referred to the Emergency department were included in the trial, for which a complete blood count and serum testosterone were obtained, along with assessing Tanner score. Patients were divided into two groups with high and low red blood cell count. Mann -Whitney U test was performed to compare Serum testosterone level and Tanner score between the groups. Pearson’s correlation coefficient was calculated to determine the correlation between red blood cell count and Testosterone levels. Results: Testosterone levels was higher in the erythrocytosis group 14.05 (SD 5.53) vs non erythrocytosis group 11.94 (SD 7.38) although it did not meet statistical significance (p-value = 0.168). There is a weak positive correlation (Pearson’s R = 0.146) between testosterone and erythrocyte levels. Conclusion: In healthy adolescent males, whose serum testosterone levels are within normal range we observed erythrocytosis in 22% of patients. Testosterone levels was positively correlated with","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69350451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Failure to Adjust CT Scanners to Pediatric Settings is a Major Cause of Unnecessary Radiation Exposure to Children 未能将CT扫描仪调整为儿童设置是儿童不必要辐射暴露的主要原因

Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050166

Jianna J. Lin, Jeremy Zhang, Lucille Anzia, Laura L. Hayes

{"title":"Failure to Adjust CT Scanners to Pediatric Settings is a Major Cause of Unnecessary Radiation Exposure to Children","authors":"Jianna J. Lin, Jeremy Zhang, Lucille Anzia, Laura L. Hayes","doi":"10.26502/jppch.74050166","DOIUrl":"https://doi.org/10.26502/jppch.74050166","url":null,"abstract":"CT scans are an indispensable tool for evaluating head injuries and neurological symptoms, yet they are the leading contributor to medical radiation exposure in the United States. High levels of such exposure pose significant health risks for children, whose developing bodies are less resilient to radiation injury. Here we review mean radiation dose (Total Exam DLP) and CTDlvol from head CT scans of 149 cases to assess for factors thought to be potential contributors to excess radiation exposure. Such factors included scan indication (trauma, shunts, other head complaints), number of repeat scans, and the type of facility the scan was performed (adult vs. pediatric). Analyses revealed that among scans performed to evaluate head trauma or routine indications (e.g. headache, vomiting focal neurologic deficits), the mean radiation dose a administered was significantly higher in adults hospitals when compared to pediatric hospitals. Findings highlight the importance of ensuring appropriate dose settings to increase the safety of CT scans for children. Based on our results identifying suboptimal scanner settings as a fundamental cause of excess radiation exposure, the evidence supports adjusting protocols to appropriate settings as the most effective method of reducing excess radiation exposure to children receiving head CT scans.","PeriodicalId":73894,"journal":{"name":"Journal of pediatrics, perinatology and child health","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135060165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic of Sepsis in a Congolese Pediatric Emergency Service Using PSOFA Score: A Prospective Study 使用PSOFA评分预测刚果儿科急诊败血症的预后:一项前瞻性研究

Journal of pediatrics, perinatology and child health Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050162

Jacques Balekelayi wa Balekelayi, Valérie Bolingo Bola, Stéphanie Mikalo Mbambi, Joseph Mabiala Bodi, Victoire Audray Bikoumou

引用次数: 0