Journal of neuro-AIDS最新文献_第4页

Microglia in HIV-related CNS neuropathology: an update. hiv相关中枢神经系统病理中的小胶质细胞:最新进展。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/j128v01n01_03

D W Dickson, S C Lee

引用次数: 19

Reduced Global Cerebral Blood Flow in Non-Demented HIV Positive Patients. 非痴呆HIV阳性患者脑血流减少

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/j128v01n04_07

O Dunlop, K Rootwelt, R Rklund, J N Bruun, D Russell, R Nyberg-Hansen

引用次数: 4

ABSTRACTSNeuroscience of
HIV Infection
Basic and Clinical
Frontiers 1994. hiv感染的神经科学，基础与临床前沿，1994。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/J128v01n02_07

H C Features Submission

引用次数: 0

Traffic of lymphocytes into the CNS during inflammation and HIV infection. 在炎症和HIV感染期间淋巴细胞进入中枢神经系统的交通。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/j128v01n01_02

K C Williams, W F Hickey

引用次数: 18

Astrocytes and the AIDS dementia complex. 星形胶质细胞与艾滋病痴呆复合体。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/j128v01n01_06

H K Patton, E N Benveniste, D J Benos

引用次数: 13

Macrophage Activation Factors
in the Brains of AIDS Patients. 艾滋病患者脑内巨噬细胞激活因子的研究。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/J128v01n02_01

C L Achim, E Masliah, M P Heyes, P Sarnacki, C Hilty, M Baldwin, C A Wiley

引用次数: 19

Neurologic Manifestations
of HIV Infection Without AIDS:Follow-UP of a Cohort
of Homosexual and Bisexual Men. 非艾滋病HIV感染的神经系统表现:一组同性恋和双性恋男性的随访。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/J128v01n02_04

C M Marra, W T Longstreth, H H Handsfield, B D Townes, R W Coombs, V L Murphy, A C Collier, C L Maxwell, K Claypoole, K R Maravilla, R Sloan, W A Cohen, S B Ross

{"title":"Neurologic Manifestations of HIV Infection Without AIDS:Follow-UP of a Cohort of Homosexual and Bisexual Men.","authors":"C M Marra, W T Longstreth, H H Handsfield, B D Townes, R W Coombs, V L Murphy, A C Collier, C L Maxwell, K Claypoole, K R Maravilla, R Sloan, W A Cohen, S B Ross","doi":"10.1300/J128v01n02_04","DOIUrl":"https://doi.org/10.1300/J128v01n02_04","url":null,"abstract":"To identify neurological abnormalities in HIV infection, 159 HIV-seropositive men without AIDS and 76 seronegative controls underwent standardized general and neurological examinations, lumbar puncture (LP), neuropsychological (NP) assessment, and brain magnetic resonance (MR) imaging. History, physical, and laboratory evaluations were repeated every six months. NP tests (all subjects) and MR imaging (seropositives only) was repeated every 6-12 months; LP (seropositives only) was repeated yearly. Mean follow-up was 24.6 months. Neurological abnormalities, most related to hearing, were seen in 60 (38.2%) of 157 seropositives and 23 (30.3%) of 76 controls at baseline (p = NS). During follow-up, 43 (31.6%) of 136 seropositives had persistent hearing abnormalities compared to 9 (14.1%) of 64 seronegatives (p = 0.008). Seven HIV-seropositives developed peripheral neuropathy; this was more common among those with hearing abnormalities (p = 0.03). HIV-seropositives performed less well on NP tests than controls, but overall performance did not decline. Worsening brain atrophy by MR imaging or cerebrospinal fluid abnormalities are more common in HIV-seropositives than seronegatives and may share a common mechanism with peripheral neuropathy. Further study is needed to determine whether these abnormalities portend more serious neurological disease.","PeriodicalId":73854,"journal":{"name":"Journal of neuro-AIDS","volume":" ","pages":"41-65"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26169049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Gender Differences in HIV-Related Neurological Progression in a Cohort of Injecting Drug Users Followed for 3.5 Years. 对注射吸毒者进行3.5年随访的hiv相关神经系统进展的性别差异

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/j128v01n04_03

X Liu, K Marder, Y Stern, G Dooneief, K Bell, G Todak, M Joseph, W Elsadr, J B Williams, A Ehrhardt, Z Stein, R Mayeux

引用次数: 13

Adequately Treated Remote Syphilis
Does Not Augment
CNS HIV-1 Expression. 适当治疗的远端梅毒不会增强中枢神经系统HIV-1表达。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/J128v01n02_06

J McArthur, L A White, J McArthur

{"title":"Adequately Treated Remote Syphilis Does Not Augment CNS HIV-1 Expression.","authors":"J McArthur, L A White, J McArthur","doi":"10.1300/J128v01n02_06","DOIUrl":"https://doi.org/10.1300/J128v01n02_06","url":null,"abstract":"Objective: The co-occurence of human immunodeficiency virus (HIV) infection and syphilis may accelerate the course of both infections. We investigated whether remote syphilis infection augmented the activation of central nervous system (CNS) HIV infection and increased the frequency of cerebrospinal fluid (CSF) abnormalities.Methods: The subjects consist of HIV seropositive men who had CSF as part of prospective neurological studies performed at the Johns Hopkins University. Prior syphilis infection was determined by measuring serum FTA-ABS. All subjects had received adequate treatment for syphilis with negative RPR's or RPR's ≤ 1:8 and completed a full neurological examination and underwent lumbar punctures for analysis of cerebrospinal fluid. A range of CSF tests were performed including HIV culture, p24 antigen, β2 microglobulin (β2M) and CSF/albumin ratios.Results: The FTA positive group was significantly older (p = .005), more advanced in HIV clinical staging (p = .04), had more minor neurological symptoms (p = .03), and was more likely to be on antiretroviral therapy (p = .03). No differences between FTA positive and FTA negative groups were observed either in the frequency of CFS anbormalities or the mean CSF values.Conclusions: Based on these findings, it appears that adequately treated remote syphilis does not augment HIV-1 expression within the CNS.","PeriodicalId":73854,"journal":{"name":"Journal of neuro-AIDS","volume":"1 2","pages":"87-96"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10407059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellular basis of HIV infection of the CNS and the AIDS dementia complex: oligodendrocyte. 艾滋病毒感染中枢神经系统和艾滋病痴呆复合体的细胞基础:少突胶质细胞。

Journal of neuro-AIDS Pub Date : 1996-01-01 DOI: 10.1300/j128v01n01_07

M M Esiri, C S Morris

引用次数: 9