{"title":"A Prelude to Engineering of Cell Microenvironment Using Novel Hydrogels","authors":"Xiaohui Zhang, Feng Xu","doi":"10.1115/1.4033192","DOIUrl":"https://doi.org/10.1115/1.4033192","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"040301"},"PeriodicalIF":0.0,"publicationDate":"2016-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4033192","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63496296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Hasanova, M. Ramazanov, A. Maharramov, S. Hajiyeva, Y. Parfyonova, G. Eyvazova, F. Hajiyeva, N. Guliyeva, S. Veliyeva
{"title":"The Improvement of Antimicrobial Activity of Kanamycin and Ciprofloxacin Antibiotics Coupled With Biocompatible Magnetite Nanoparticles and Characterization of Their Structure","authors":"U. Hasanova, M. Ramazanov, A. Maharramov, S. Hajiyeva, Y. Parfyonova, G. Eyvazova, F. Hajiyeva, N. Guliyeva, S. Veliyeva","doi":"10.1115/1.4033126","DOIUrl":"https://doi.org/10.1115/1.4033126","url":null,"abstract":"In this paper, we present the synthesis of nanostructures of magnetite nanoparticles (NPs) with ciprofloxacin and kanamycin antibiotics, based on self-assembling principle. The nanostructures were prepared in crystallite size, ranging 8–16 nm, in one pot addition setup and further washing steps, using only iron precursors and above-mentioned antibiotics as stabilizers. Nanostructures were analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD) analysis methods, Fourier transform infrared (FTIR) and ultraviolet (UV) spectroscopy methods. It was found that they have well-shaped spherical form and are homogeneous in size. The quantitative analysis of nanostructured antibiotics was performed by atom absorbance spectroscopy (AAS) as well as on the basis of Lambert–Beer law. Prepared nanostructures were tested on Staphylococcus aureus and Pseudomonas aeruginosa. Obtained results demonstrated that these nanostructures are able to improve antimicrobial properties and decrease the minimal inhibitory concentration (MIC) of pristine kanamycin and ciprofloxacin antibiotics.","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"041006"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4033126","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63496054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On-Chip Cytotoxicity Testing of Nepali Chiya Extract","authors":"Sueon Kim, I. H. Jang, Won Gu Lee","doi":"10.1115/1.4033194","DOIUrl":"https://doi.org/10.1115/1.4033194","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"103 1","pages":"041004"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4033194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63496343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Sessions, Bradley Hanks, D. Lindstrom, S. Hope, B. Jensen
{"title":"Transient Low-Temperature Effects on Propidium Iodide Uptake in Lance Array Nanoinjected HeLa Cells","authors":"J. Sessions, Bradley Hanks, D. Lindstrom, S. Hope, B. Jensen","doi":"10.1115/1.4033323","DOIUrl":"https://doi.org/10.1115/1.4033323","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"041005"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4033323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63496461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Engineering a Three-Dimensional In Vitro Drug Testing Platform for Glioblastoma","authors":"M. Akay, D. Nguyen, Yantao Fan, Y. Akay","doi":"10.1115/1.4032903","DOIUrl":"https://doi.org/10.1115/1.4032903","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"041002"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4032903","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63495662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Prelude to Fractal Engineering and Biomedicine","authors":"C. Doumanidis","doi":"10.1115/1.4033099","DOIUrl":"https://doi.org/10.1115/1.4033099","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"040201"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4033099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63496001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DNA-Based Bulk Hydrogel Materials and Biomedical Application","authors":"Yanmin Gao, Hao Qi","doi":"10.1115/1.4032832","DOIUrl":"https://doi.org/10.1115/1.4032832","url":null,"abstract":"Being a natural polymer, DNA attracts extensive attention and possesses great potential to open a new way for researches of biomedical or material science. In the past few decades, approaches have been developed to bring DNA into the realm of bulk materials. In this review, we discussed the progresses achieved for fabrication of novel materials with a large physical dimension from the DNA polymer.","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"040802"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4032832","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63495798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baoqiang Li, Lei Wang, Yuzhou Hao, Daqing Wei, Ying Li, Yujie Feng, D. Jia, Yu Zhou
{"title":"Ultraviolet-Crosslinkable and Injectable Chitosan/Hydroxyapatite Hybrid Hydrogel for Critical Size Calvarial Defect Repair In Vivo","authors":"Baoqiang Li, Lei Wang, Yuzhou Hao, Daqing Wei, Ying Li, Yujie Feng, D. Jia, Yu Zhou","doi":"10.1115/1.4032902","DOIUrl":"https://doi.org/10.1115/1.4032902","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"041001"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4032902","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63495624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical Study of Composite Electrode's Particle Size Effect on the Electrochemical and Heat Generation of a Li-Ion Battery","authors":"A. N. Shirazi, M. Kakavand, T. Rabczuk","doi":"10.1115/1.4032012","DOIUrl":"https://doi.org/10.1115/1.4032012","url":null,"abstract":"","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"041003"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4032012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63493158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Engineering Embryonic Stem Cell Microenvironments for Tailored Cellular Differentiation","authors":"Chenyu Huang, A. Melerzanov, Yanan Du","doi":"10.1115/1.4033193","DOIUrl":"https://doi.org/10.1115/1.4033193","url":null,"abstract":"The rapid progress of embryonic stem cell (ESCs) research offers great promise for drug discovery, tissue engineering, and regenerative medicine. However, a major limitation in translation of ESCs technology to pharmaceutical and clinical applications is how to induce their differentiation into tailored lineage commitment with satisfactory efficiency. Many studies indicate that this lineage commitment is precisely controlled by the ESC microenvironment in vivo. Engineering and biomaterial-based approaches to recreate a biomimetic cellular microenvironment provide valuable strategies for directing ESCs differentiation to specific lineages in vitro. In this review, we summarize and examine the recent advances in application of engineering and biomaterial-based approaches to control ESC differentiation. We focus on physical strategies (e.g., geometrical constraint, mechanical stimulation, extracellular matrix (ECM) stiffness, and topography) and biochemical approaches (e.g., genetic engineering, soluble bioactive factors, coculture, and synthetic small molecules), and highlight the three-dimensional (3D) hydrogel-based microenvironment for directed ESC differentiation. Finally, future perspectives in ESCs engineering are provided for the subsequent advancement of this promising research direction.","PeriodicalId":73845,"journal":{"name":"Journal of nanotechnology in engineering and medicine","volume":"6 1","pages":"040801"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/1.4033193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63496335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}