{"title":"Accessory Hepatic Lobe in Paediatric Patients: Case Report and a Comprehensive Literature Review","authors":"Accessory hepatic lobe • Ectopic liver tissue • Accessory li Omphalocele","doi":"10.37421/2165-7920.2021.11.1467","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1467","url":null,"abstract":"Background: Accessory Hepatic Lobe (AHL) is a rare congenital anomaly that consists of the presence of a supernumerary lobe of hepatic parenchyma. The incidence of AHL is less than 1%, with only 27 cases having been reported in the paediatric population to date. Aim: To identify studies in the literature on accessory hepatic lobe and present our experience with this condition. Material and methods: We report the case of a patient who underwent surgery for intestinal occlusion and was found to have an accessory liver lobe with an embedded gallbladder. We reviewed published articles on accessory hepatic lobes accessed via PubMed, Google Scholar, Science Direct and Web of Science. Keywords included accessory hepatic lobe, ectopic liver tissue, ectopic liver lobe, accessory liver lobe. The search included articles published before August 2021 in English. Results: We identified 27 published cases of paediatric accessory hepatic lobe. Of these 27, 14 were female and 13 were male, and the age range was 1 day to 19 years. We report the case of a female patient with intestinal occlusion found to have an accessory hepatic lobe with an embedded gallbladder. Of the 28 published cases, including ours, 11 are associated with abdominal wall defects including Umbilical Hernia, Omphalocele, Cloacal Exstrophy and Beckwith Wiedemann syndrome. Conclusion: Accessory hepatic lobe is a rare entity usually detected incidentally. A total of 28 cases were reported, including our own. Paediatric surgeons should be aware of this condition in children with a history of abdominal wall defects.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Septic Shock Complicated with Limb Ischemic Necrosis: Three Case Reports and their Review of Literature","authors":"Zheng Li","doi":"10.37421/2165-7920.2021.11.1450","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1450","url":null,"abstract":"Purpose: Limb ischemic necrosis is a very rare but severe condition that generally leads to amputation in septic shock. Our aim is to review the risk factors for development of limb ischemic necrosis in ICU patients requiring vasopressor support and draw the attention of doctors. Methods: A retrospective review of clinical information and photographs in 3 septic shock patients, including APACHII scores, dose of norepinephrine, time of ischemic necrosis and final outcome from July 2001 to June 2020 at a single intensive care unit. Results: All of the three patients had high APACHE II score, obvious coagulation dysfunction and severe hypotension on admission; In order to maintain the target blood pressure, the dose of norepinephrine range from 0.36 to 7.27 μg/kg/min; Case 2 and 3 had a higher average dose and length of NE treatment when comparing to case 1. Finally, case 1 survived but undergone amputation, case 2 and case 3 died. Conclusion: Septic shock with limb ischemic necrosis is a very serious complication and may indicate a poor prognosis. As an ICU doctor, we should pay attention to the complication in our clinical practice which can greatly affect patient’s quality of later life.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two Cases of Hemifacial Spasm Completely Recovered after Repeated BTX-A Treatment","authors":"T. Shen, Yingying Xu, Jing-Liu, W. Luo, Xia Zhang","doi":"10.37421/2165-7920.2021.11.1458","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1458","url":null,"abstract":"Hemifacial Spasm (HSF) refers to the intermittently involuntary clonic twitch or painless rigidity of one or two sides of facial muscles. Patients with hemifacial spasm generally have a decline in quality of life, accompanied by anxiety, depression and other emotional problems, which further aggravate hemifacial spasm symptoms. BTX-A injection is the first choice for treatment of HFS, which can not only relief the symptoms of HFS but also improve the mood problems. There have been no reported cases of HFS cured by drugs or BTX-A. Here we reported two HFS patients recovered after multiple BTX-A treatments without recurrence for 3-8 years, which might provide a clue for further exploration of the pathogenesis of HFS.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shazia Durdana, M. Zaheer, Syed Hasan Amir, S. Khan
{"title":"Acquired Bartters Syndrome: A Rare Metabolic Abnormality Induced by Streptomycin","authors":"Shazia Durdana, M. Zaheer, Syed Hasan Amir, S. Khan","doi":"10.37421/2165-7920.2021.11.1466","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1466","url":null,"abstract":"Streptomycin associated nephrotoxicity can manifest either as nonoliguric acute kidney injury, tubular dysfunction or electrolyte abnormalities including Fanconi-like syndrome or Bartter syndrome. We report a case of Streptomycin-induced renal electrolyte wasting mimicking Bartter’s syndrome.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Tabrizi, Mehrdad Dehghanpour Barouj, P. Behnia, P. Bakhshaei
{"title":"Soft Tissue Coverage with Submental Flap in Massive Medication-Related Osteonecrosis of the Mandible","authors":"R. Tabrizi, Mehrdad Dehghanpour Barouj, P. Behnia, P. Bakhshaei","doi":"10.37421/2165-7920.2021.11.1461","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1461","url":null,"abstract":"Intravenous Bisphosphonates (BPs) are used to treat cancer-related conditions, including hyperkalemia of malignancy, Skeletal-Related Events (SREs) associated with bone, and for management of lytic lesions in the setting of multiple myeloma. Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is a severe complication of BPs, which affects the patient's quality of life. In the treatment of BRONJ, soft tissue coverage for coverage of the debrided bone is essential. In severe soft tissue deficiency, the use of local or distant soft tissue flap is necessary this case report; a massive BRONJ was described in which a submental flap was used to cover the mandibular bone.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aashish Sreeram, A. Matos, N. Amin, J. Turgeon, Katie Meyer, ni Bardolia
{"title":"Pharmacists Role in Deprescribing Medications in An Adult with End-Stage Kidney Disease","authors":"Aashish Sreeram, A. Matos, N. Amin, J. Turgeon, Katie Meyer, ni Bardolia","doi":"10.37421/2165-7920.2021.11.1465","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1465","url":null,"abstract":"Purpose: Individuals diagnosed with End-Stage Kidney Disease (ESKD) have multiple comorbidities and require many medications. Alterations in renal function, coupled with pharmacokinetic and pharmacodynamic changes in individuals with increasing age, can result in adverse drug effects. The purpose of this case is to demonstrate how interventions recommended by a clinical pharmacist improved medication safety for a patient with ESKD. Case: A 55-year-old male with a past medical history of ESKD, peripheral artery disease, chronic heart failure, cirrhosis, and major depressive disorder had a clinical pharmacist-led medication review. During the review, the clinical pharmacist identified several medications (i.e., bumetanide, metolazone, spironolactone, rivaroxaban) that should be discontinued since the patient had no urinary flow output and was on dialysis. Before the recommendations were addressed, the patient experienced retinal hemorrhaging, which may have been a rivaroxaban-associated adverse drug reaction. After addressing the retinal hemorrhaging, the physician discontinued the rivaroxaban and initiated clopidogrel. Additionally, both bumetanide and metolazone were discontinued. Conclusion: This case demonstrates that clinical pharmacists can have a significant role in medication therapy management and medication safety, especially in patients with ESKD. Healthcare providers with patients with ESKD on dialysis can greatly benefit from consulting with a clinical pharmacist who can evaluate all medications for safety and efficacy.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mansour, R. Aoun, Maroua Melliti, A. Kacem, Meriem Mselmani, R. Mrissa, J. Zaouali
{"title":"A First Case of Adrenomyeloneuropathy with Mutation R152C: A Case Report with Literature Review","authors":"M. Mansour, R. Aoun, Maroua Melliti, A. Kacem, Meriem Mselmani, R. Mrissa, J. Zaouali","doi":"10.37421/2165-7920.2021.11.1445","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1445","url":null,"abstract":"X-linked Adrenoleukodystrophy (X-ALD) is a rare genetic disorder responsible of accumulation of Very Long Chain Fatty Acids (VLCFAs) which accumulate in the central nervous system, adrenal cortex and testes. Various mutations have been identified, the X-ALD mutation database catalogs 2707 (last updated on 04-03-2019) with 61% of missense mutations. This paper reports on a first case of AMN with R152C mutation in ABCD1 gene.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parietal Abcess Revealing Several Foci of Extramedullary Hematopoiesis: A Case Report","authors":"Y. Gharbi","doi":"10.37421/2165-7920.2021.11.1459","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1459","url":null,"abstract":"In children, Extra Medullary Hematopoiesis (EMH) is a compensatory response to severe chronic anemia, particularly in the context of B thalassemia. Its localization, variable, is mainly hepatic, splenic and ganglionic but all the other organs, including the skin, can be reached. Rare, most often asymptomatic, EMH can be manifested by a mass syndrome. The anamnesis and the imaging bring arguments in favor of the diagnosis, sometimes difficult to establish, without resorting to invasive examinations. Thanks to therapeutic progress, the surgical treatment has become rare, reserved for certain special cases. We report the case of a patient with major B thalassemia, in whom the appearance of an abscessed abdominal mass has revealed several foci of EMH.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Report on Causes and Prevention of Cancer","authors":"J. Callaghan","doi":"10.37421/2165-7920.2021.11.1472","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1472","url":null,"abstract":"","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ruptured Hematosalpinx: An Unconventional Cause of Hemoperitoneum in Early Pregnancy","authors":"C. Kambasha, N. Prasad, P. Jamjute, H. Moukarram","doi":"10.37421/2165-7920.2021.11.1446","DOIUrl":"https://doi.org/10.37421/2165-7920.2021.11.1446","url":null,"abstract":"Hemoperitoneum with an adnexal mass in reproductive age group women points to a life-threatening differential diagnosis of a ruptured ectopic pregnancy. Rarely isolated tubal pathology such tubal torsion with hematosalpinx may mimic such a picture and the diagnosis is difficult in hemodynamically compromised patients. This is a case report of isolated hematosalpinx without torsion in early pregnancy which was histologically confirmed following surgical management.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"11 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70049257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}