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The Experiences of Buprenorphine (Sovenor ® ) via Transdermal Patch in Elderly with Poor Renal Function 丁丙诺啡(Sovenor®)经皮贴片治疗老年人肾功能不佳的体会
Journal of clinical case reports Pub Date : 2018-04-24 DOI: 10.4172/2165-7920.10001096
Tseng Hc, Chen Jy, Chen Wt
{"title":"The Experiences of Buprenorphine (Sovenor ® ) via Transdermal Patch in Elderly with Poor Renal Function","authors":"Tseng Hc, Chen Jy, Chen Wt","doi":"10.4172/2165-7920.10001096","DOIUrl":"https://doi.org/10.4172/2165-7920.10001096","url":null,"abstract":"Transdermal buprenorphine is an opioid analgesic used in the management of moderate-severe pain via transdermal pathway. The case series is to discuss the efficacy and safety of transdermal buprenorphine (Sovenor®) in elderly patients with chronic low back pain under renal function impairment condition. \u0000We presented 4 cases demonstrating successful therapy in management of chronic severe low back pain in elderly, who were with poor renal function. Transdermal buprenorphine benefited significantly in those patients’ symptoms, and the elderly tolerated transdermal buprenorphine well under good compliance.. \u0000In conclusion, transdermal buprenorphine is effective in treating chronic neuropathic pain, and to be a safe analgesic for the elderly. In light of evidence for efficacy, safety, tolerability, and cost, physicians may consider transdermal buprenorphine as the priority choice as pain management in the elderly.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42204773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Precursor B-cell Acute Lymphoblastic Leukemia Occurre d with Rapid Hip Bone Destruction and Femoral Neck Fracture 前体b细胞急性淋巴细胞白血病伴快速髋部骨破坏及股骨颈骨折1例
Journal of clinical case reports Pub Date : 2018-04-24 DOI: 10.4172/2165-7920.10001098
Yutaka Suzuki, T. Asano, D. Takahashi, T. Irie, Ryuta Arai, Yuko Cho, A. Iguchi, M. Terkawi, N. Iwasaki
{"title":"A Case of Precursor B-cell Acute Lymphoblastic Leukemia Occurre d with Rapid Hip Bone Destruction and Femoral Neck Fracture","authors":"Yutaka Suzuki, T. Asano, D. Takahashi, T. Irie, Ryuta Arai, Yuko Cho, A. Iguchi, M. Terkawi, N. Iwasaki","doi":"10.4172/2165-7920.10001098","DOIUrl":"https://doi.org/10.4172/2165-7920.10001098","url":null,"abstract":"Background: Precursor B-cell lymphoblastic lymphoma is a rare subtype of acute lymphoblastic lymphoma and sometimes presents as lytic bone lesions. Diagnosis and treatment of lytic bone lesions are always challenging. This is a rare case of delayed leukemic change of precursor B-cell acute lymphoblastic lymphoma presented with a rapid hip bone destruction. \u0000Case presentation: A 12-year-old Japanese girl presented with progressive left hip pain, and bone destruction of her left hip two months after the onset of symptoms. She had no past medical or family history of malignancy and had no genetic abnormality. Radiograph and MRI examination showed bone destruction and osteolytic lesions in her left femoral neck and pelvis. Blast cells were not found in our initial examination of the peripheral blood and aspirated bone marrow cells. The case was finally diagnosed as Precursor B-cell lymphoblastic lymphoma as the results of bone biopsy, and blast cells were then detected after preforming multiple bone marrow aspirations. She also had pathological femoral neck fracture, but after treatment regimen by chemotherapy, her osteolytic lesions cured with obtainment of femoral neck fusion. She could walk at the final period. \u0000Conclusion: This case highlights the importance of early diagnosis of this disease for greater curing rates. Diagnosis of Precursor B-cell lymphoblastic lymphoma was finally made based on the results of biopsy of tissues because of the delayed appearance of leukemic changes. Orthopaedic surgeons should be aware of Precursor B-cell lymphoblastic lymphoma, when making diagnosis of patients exhibiting a rapid hip bone destruction.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46348138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bone Undifferentiated Pleomorphic Sarcoma – A Case Report 骨未分化多形性肉瘤一例报告
Journal of clinical case reports Pub Date : 2018-04-23 DOI: 10.4172/2165-7920.10001095
André Costa, B. Santos, C. Mateus, L. Fardilha, Gomes, I. Silva, Pedro Varanda, N. Sevivas
{"title":"Bone Undifferentiated Pleomorphic Sarcoma – A Case Report","authors":"André Costa, B. Santos, C. Mateus, L. Fardilha, Gomes, I. Silva, Pedro Varanda, N. Sevivas","doi":"10.4172/2165-7920.10001095","DOIUrl":"https://doi.org/10.4172/2165-7920.10001095","url":null,"abstract":"Bone sarcomas are a rare group of tumors arising mostly in the extremities, being the undifferentiated pleomorphic sarcoma (UPS), also known as malignant fibrous histiocytoma, the most common. UPS exhibits a wide spectrum of clinical behavior and a diagnosis challenge. We report a clinical case of a proximal humeral UPS that presented with a non-recognized pathological fracture, initially treated with open reduction and internal fixation. Suboptimal postoperative management of the patient, leading to a diagnosis delay, occurred related to its hematoid transformation, a variant of aggressive high-grade sarcoma associated with a worse prognosis. Pulmonary embolic complication, external axillary vein compression, rapidly tumor growth and diffuse metastization were some characteristics. Abrupt disease development makes important to recognize the clinical features of those tumors, so better outcomes can be obtained.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47381477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote Primary Intraventricular Haemorrhage in Case of a Ruptur ed MCA Aneurysm Ruptured MCA动脉瘤的远端原发性脑室内出血
Journal of clinical case reports Pub Date : 2018-04-23 DOI: 10.4172/2165-7920.10001093
Redmond Jg, Pattavilakom Sa
{"title":"Remote Primary Intraventricular Haemorrhage in Case of a Ruptur ed MCA Aneurysm","authors":"Redmond Jg, Pattavilakom Sa","doi":"10.4172/2165-7920.10001093","DOIUrl":"https://doi.org/10.4172/2165-7920.10001093","url":null,"abstract":"This is the first documented case report of a simultaneous middle cerebral artery (MCA) aneurysmal subarachnoid hemorrhage (aSAH) and remote third ventricular clot. The occurrence of simultaneous subarachnoid hemorrhage and remote hypertensive intracerebral hemorrhage (ICH) is a rare occurrence and has only been reported three previous times in the literature. Intraventricular hemorrhage (IVH) post aneurysmal subarachnoid hemorrhage is common, where peri-ventricular intracerebral clot has ruptured the ependymal lining. However primary intraventricular hemorrhage (PIVH) without associated parenchymal clot is rare. Migration of blood via outlet foramina of the fourth ventricle through CSF pulsation and flow is thought to be the mechanism for this occurrence and would account for small volumes in the subacute setting. Here, we present a case of a 52-year-old woman with a CT demonstrated spontaneous middle cerebral artery (MCA) bifurcation aneurysmal subarachnoid hemorrhage and a large acute third ventricular clot spanning the foramen Monroe.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46438348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic Steroids, Clarithromycin and Metronidazole in the Trea tment of Rosacea during Pregnancy 全身性类固醇、克拉霉素和甲硝唑治疗妊娠期酒渣鼻
Journal of clinical case reports Pub Date : 2018-04-23 DOI: 10.4172/2165-7920.10001100
B. Clanner-Engelshofen, H. Schwaiger, G. Plewig, H. Wolff, T. Ruzicka, M. Reinholz
{"title":"Systemic Steroids, Clarithromycin and Metronidazole in the Trea tment of Rosacea during Pregnancy","authors":"B. Clanner-Engelshofen, H. Schwaiger, G. Plewig, H. Wolff, T. Ruzicka, M. Reinholz","doi":"10.4172/2165-7920.10001100","DOIUrl":"https://doi.org/10.4172/2165-7920.10001100","url":null,"abstract":"Rosacea is a common skin disease with a predilection for the face. Patients suffer from symptoms like flushing, redness of the face, telangiectasia, pustules, or papules. A more acute form is rosacea fulminans that occurs preferentially in women. Hormonal fluctuations as during a pregnancy can aggravate existent rosacea. The case of a female patient is presented, who was in the 26th week of her pregnancy. She discontinued her usual rosacea medication when she became pregnant. The patient developed rosacea fulminans, which was treated with systemic corticosteroids as recommended. She responded well to clarithromycin 250 mg for three times a week in combination with topical treatment using metronidazole 0.75% creme, continuing this regimen until a stable result was obtained. Based on the observations in this case study the therapy of rosacea fulminans with clarithromycin can help to reduce the symptoms, especially since treatment with systemic isotretinoin and doxycycline is contraindicated during pregnancy.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44601213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Tumor in a 15-Year-Old Patient 一名15岁患者的心脏肿瘤
Journal of clinical case reports Pub Date : 2018-04-13 DOI: 10.4172/2165-7920.10001102
S. Milouchi, A. Sghaier, H. Ajmi, K. Ali, Ferjani Souad
{"title":"Cardiac Tumor in a 15-Year-Old Patient","authors":"S. Milouchi, A. Sghaier, H. Ajmi, K. Ali, Ferjani Souad","doi":"10.4172/2165-7920.10001102","DOIUrl":"https://doi.org/10.4172/2165-7920.10001102","url":null,"abstract":"Tumors of the heart are a very rare disease in cardiology practice. They are more frequently benign. Neonatal diagnosis is possible, but the accidental late discovery of a cardiac mass remains the most common situation. We report a case of a cardiac tumor in a 15-year-old patient symptomatic of palpitations. The belonging of the tissue to the cardiac muscle was confirmed on echocardiography and on other radiological findings. Regular monitoring was chosen at first then surgical resection was decided as an increase in the tumor’s size was noted on the echocardiographic control.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48957349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucose Abnormalities in Hypothyroidism 甲状腺功能减退症的葡萄糖异常
Journal of clinical case reports Pub Date : 2018-04-13 DOI: 10.5376/IJCCR.2018.08.0003
S. Azzoug, Souad Chellali, Fatma Zohra Boudissa, E. Koceir, D. Meskine, F. Chentli
{"title":"Glucose Abnormalities in Hypothyroidism","authors":"S. Azzoug, Souad Chellali, Fatma Zohra Boudissa, E. Koceir, D. Meskine, F. Chentli","doi":"10.5376/IJCCR.2018.08.0003","DOIUrl":"https://doi.org/10.5376/IJCCR.2018.08.0003","url":null,"abstract":"It is classically known that thyroid hormones excess or hyperthyroidism induce hyperglycemia. However, thyroid hormone deficiency or hypothyroidism can also induce glucose abnormalities through the development of abdominal obesity and insulin resistance. The aim of our study was to assess the frequency and predictive factors of glucose abnormalities during hypothyroidism. In this retrospective study, we included 425 patients (383 F/42 M) presenting with primary hypothyroidism. We investigated the presence of hyperglycemia, either fasting (≥100 mg/dl) and/or at 2 hours after an oral glucose tolerance test with 75 grams of glucose (≥140 mg/dl). Hyperglycemia was found in 37.6%. Subjects with hyperglycemia were older than those with normoglycemia (54.4±1.08 vs. 45.7±0.8 years), their Body Mass Index (BMI) was higher (31.5±0.53 vs. 28.7±0.37 kg/m 2 ), they had higher blood pressure (54.3% vs. 21.5%) and a family history of diabetes (36.2% vs. 29.8%). We conclude that glucose abnormalities are frequent in hypothyroidism and are developed mostly in patients with risk factors for insulin resistance such as age, high blood pressure and a positive family history of type 2 diabetes.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45754970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salvage Procedure after Sternochondroplasty for Pectus Excavatu m 胸骨软骨成形术后的抢救方法
Journal of clinical case reports Pub Date : 2018-03-31 DOI: 10.4172/2165-7920.10001097
B. Aramini, U. Morandi, G. Santis, A. Baccarani
{"title":"Salvage Procedure after Sternochondroplasty for Pectus Excavatu m","authors":"B. Aramini, U. Morandi, G. Santis, A. Baccarani","doi":"10.4172/2165-7920.10001097","DOIUrl":"https://doi.org/10.4172/2165-7920.10001097","url":null,"abstract":"Vacuum-Assisted Closure (VAC) in association to flap reconstruction is a well-established approach for treating complicated wounds. \u0000The authors present a case of soft-tissue breakdown with hardware exposure in a patient treated with modified Ravitch procedure for pectus excavatum. VAC therapy was applied in association to multiple debridement procedures and final flap closure. This was achieved without the need for hardware removal, thus maintaining adequate skeletal fixation. To our knowledge this approach has not yet been described into the literature after sternochondroplasty procedure. \u0000Aggressive debridement and VAC therapy before final closure may represent a new, conservative method for managing surgical complications after sternochondroplasty procedures.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49025833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iron Deficiency Thrombocytopenia: A Case Report and Review of the Literature 缺铁性血小板减少症1例报告及文献复习
Journal of clinical case reports Pub Date : 2018-03-30 DOI: 10.4172/2165-7920.10001090
B. J. Hassan, M. Campos
{"title":"Iron Deficiency Thrombocytopenia: A Case Report and Review of the Literature","authors":"B. J. Hassan, M. Campos","doi":"10.4172/2165-7920.10001090","DOIUrl":"https://doi.org/10.4172/2165-7920.10001090","url":null,"abstract":"Iron deficiency is a common cause of anemia in premenopausal women. Thrombocytopenia is rarely found in association with iron deficiency anemia (IDA), and its mechanism is not fully understood. Here, we present the case of a 41-year-old African-American woman who was found to have severe asymptomatic thrombocytopenia (platelet count 22,000/μL) in association with more moderate IDA (hemoglobin 8.5 g/dL). Both cytopenias resolved with oral iron replacement therapy in the absence of other therapeutics, such as corticosteroid therapy, and a diagnostic workup revealed no other cause for thrombocytopenia. We conclude that iron deficiency-associated thrombocytopenia should be considered in any case of thrombocytopenia accompanying IDA. Response of both anemia and thrombocytopenia to iron therapy should obviate the need for expensive evaluations and bone marrow examination.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"8 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41849218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case Report of Danon Disease 达侬病1例报告
Journal of clinical case reports Pub Date : 2018-03-30 DOI: 10.4172/2165-7920.10001089
Olusanya Aa, Balachandran Kp
{"title":"A Case Report of Danon Disease","authors":"Olusanya Aa, Balachandran Kp","doi":"10.4172/2165-7920.10001089","DOIUrl":"https://doi.org/10.4172/2165-7920.10001089","url":null,"abstract":"We present a case of a 21-year-old gentleman with background history of moderate learning disability, Type 1 Diabetes Mellitus and elevated ALT. Due to incidental finding of a double apical impulse and abnormal ECG was referred for cardiology review. His echocardiogram findings triggered a cascade of other investigations which eventually resulted into genetic testing that confirmed Danon disease. \u0000He had a high HCM risk-SCD score and therefore had an ICD implant but unfortunately due to poor diabetic control, he was unlisted from heart transplant list. About 5 years after his formal diagnosis, he developed decompensated and congestive heart failure despite optimal medical therapy. He unfortunately passed away due to end-stage heart failure.","PeriodicalId":73664,"journal":{"name":"Journal of clinical case reports","volume":"8 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2165-7920.10001089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70702975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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