Journal of cardiology case reports最新文献_第3页

Abordaje laparoscópico exitoso de lesión vesical intraperitoneal ocasionada durante una cirugía ginecológica. Reporte de caso 妇科手术中腹腔内膀胱损伤的成功腹腔镜治疗。个案报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.91624

David Andrés Castañeda Millán, Carlos Hernán Abonia Velasco, Juan Camilo Álvarez Restrepo, Christian Buitrago Carrascal, Edith Ángel Muller, Wilfredo Donoso Donoso

{"title":"Abordaje laparoscópico exitoso de lesión vesical intraperitoneal ocasionada durante una cirugía ginecológica. Reporte de caso","authors":"David Andrés Castañeda Millán, Carlos Hernán Abonia Velasco, Juan Camilo Álvarez Restrepo, Christian Buitrago Carrascal, Edith Ángel Muller, Wilfredo Donoso Donoso","doi":"10.15446/cr.v8n1.91624","DOIUrl":"https://doi.org/10.15446/cr.v8n1.91624","url":null,"abstract":"Introduction: Urinary tract injuries are common in the context of pelvic surgery; however, there is little information in the medical literature on the management of these injuries using a laparoscopic approach. The following is the clinical case of a patient with intraperitoneal bladder injury secondary to gynecological pelvic surgery that was successfully treated using a laparoscopic approach. Moreover, a management algorithm is proposed based on the scientific data available.\u0000Case report. A 39-year-old female patient was admitted to the hospital with generalized abdominal pain and anuria three days after undergoing a left laparoscopic salpingectomy and resection of a migrated intrauterine device. Laboratory tests showed microhematuria, serum creatinine of 4.35mg/dL, and urea nitrogen of 35.2mg/dL. Computed tomography cystography showed a solution of continuity on the left posterolateral intraperitoneal bladder. The patient underwent successful laparoscopic treatment for the bladder injury, and two weeks later, retrograde cystography confirmed its adequate resolution.\u0000Conclusions. Based on the benefits of the laparoscopic approach and after extrapolating the outcomes of the laparoscopic management of bladder trauma, it can be concluded that the laparoscopic approach to surgical injuries of the bladder is a feasible therapeutic option.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88980166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital syphilis confirmed by PCR as a result of treatment failure for syphilis in pregnancy. Case report 妊娠期梅毒治疗失败经PCR证实为先天性梅毒。病例报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.91044

Mery Yolanda Cifuentes Cifuentes, Linda Stefany Gómez Aristizábal, Gladys Pinilla Bermúdez, C. Cruz, Jeannette Navarrete

{"title":"Congenital syphilis confirmed by PCR as a result of treatment failure for syphilis in pregnancy. Case report","authors":"Mery Yolanda Cifuentes Cifuentes, Linda Stefany Gómez Aristizábal, Gladys Pinilla Bermúdez, C. Cruz, Jeannette Navarrete","doi":"10.15446/cr.v8n1.91044","DOIUrl":"https://doi.org/10.15446/cr.v8n1.91044","url":null,"abstract":"Introduction: Congenital syphilis is a major public health problem, and early diagnosis and treatment are necessary to prevent it. Penicillin G benzathine is the treatment of choice in pregnant women; however, it may fail to prevent fetal infection, as in the present case.\u0000Case presentation: Male newborn, son of an HIV negative mother with gestational syphilis (venereal disease research laboratory (VDRL) 1:4 dilution, positive treponemal test) diagnosed at week 21 of gestation and treated with three doses of 2 400 000 IU of penicillin G benzathine. At delivery, the mother presented VDRL 1:1 dilution. The newborn was diagnosed with congenital syphilis due to VDRL 1:4 dilution, positive treponemal test, elevated aspartate aminotransferases, hyposthenuria, proteinuria, hematuria, and leukocyturia that resolved after treatment with crystalline penicillin for 10 days. The molecular testing in blood showed a high treponemal load. The VDRL test at 3 months was non-reactive.\u0000Conclusions: Preventing congenital syphilis with the recommended treatment for gestational syphilis may fail. Moreover, diagnosing this condition in an asymptomatic newborn is difficult. Therefore, clinical and serological tests are recommended to confirm whether maternal treatment was effective in the fetus.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88697554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Methotrexate nephrotoxicity in a patient with preserved renal function. Case report 甲氨蝶呤肾毒性对肾功能保留患者的影响。病例报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.92651

Juan José Ríos Valbuena, Paola Karina García Padilla, Carolina Ardila Hani

{"title":"Methotrexate nephrotoxicity in a patient with preserved renal function. Case report","authors":"Juan José Ríos Valbuena, Paola Karina García Padilla, Carolina Ardila Hani","doi":"10.15446/cr.v8n1.92651","DOIUrl":"https://doi.org/10.15446/cr.v8n1.92651","url":null,"abstract":"Introduction: Methotrexate is a drug with chemotherapeutic properties frequently used for the treatment of certain types of cancer. The following is a clinical case which, to the best of the authors’ knowledge, is the first report in Colombia on nephrotoxicity caused by this drug and describes the consequences as well as the treatment provided at a quaternary care hospital.\u0000Case report: A 71-year-old patient with a diagnosis of non-Hodgkin’s lymphoma with normal renal function underwent chemotherapy (high-dose methotrexate intravenously) and developed stage 3 acute renal failure according to the KDIGO guidelines, which was most likely related to methotrexate intake. The patient received treatment with intravenous fluids and sodium bicarbonate as promoters of urine excretion of the toxin, and oral calcium folinate following the institutional protocol. The patient was discharged with recovery of kidney function and improved creatinine and urea nitrogen levels.\u0000Conclusion: The treatment given to the patient in this case report shows that although methotrexate nephrotoxicity is a potentially serious entity, it can have a good prognosis if treated promptly.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83128594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Folliculitis decalvans: a case report of satisfactory recovery after implementing isotretinoin therapy 异维甲酸治疗后毛囊炎恢复满意1例

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.88800

J. F. Porras-Villamil, Ángela Catalina Hinestroza-Ruiz, Doris Juliana Parra-Sepúlveda, G. López-Moreno

{"title":"Folliculitis decalvans: a case report of satisfactory recovery after implementing isotretinoin therapy","authors":"J. F. Porras-Villamil, Ángela Catalina Hinestroza-Ruiz, Doris Juliana Parra-Sepúlveda, G. López-Moreno","doi":"10.15446/cr.v8n1.88800","DOIUrl":"https://doi.org/10.15446/cr.v8n1.88800","url":null,"abstract":"Introduction: Folliculitis decalvans is a rare skin disease characterized by the presence of painful papules and pustules with an underlying neutrophilic infiltrate, usually on the scalp. Its treatment is lengthy and challenging, and recurrence is relatively common. Although its etiology is unknown, several theories explaining its development have been proposed, including colonization by Staphylococcus aureus.\u0000Case description: This is the case of a 26-year-old male healthcare worker who visited the outpatient service after experiencing a 4-year history of painful pustules on the scalp; initially these lesions were located in the occipital region, but then also started to appear in the temporal and parietal regions. After being treated for bacterial folliculitis and having several recurrences, a skin biopsy was performed, which allowed diagnosing him with folliculitis decalvans. Once the diagnosis was made, isotretinoin (20mg) treatment was implemented for a year and a half, achieving complete remission of the lesions.\u0000Conclusion: Although this case has some limitations, such as the lack of histopathology images and some control laboratory tests, it clearly shows the difficulties faced when treating this type of skin disorders and presents an overview of the use of isotretinoin, evidencing that although this drug is well tolerated, possible adverse reactions from drug interactions with trimethoprim/sulfamethoxazole may arise. In addition, this case is of great importance since the possible presence of a familial cluster of folliculitis decalvans could be confirmed, if further genetic testing is performed.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77824879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hereditary spastic paraplegia due to NIPA1 gene mutation: Case report NIPA1基因突变致遗传性痉挛性截瘫1例

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.90865

Dary Jizeth Parra-Párraga, E. Espinosa-García

{"title":"Hereditary spastic paraplegia due to NIPA1 gene mutation: Case report","authors":"Dary Jizeth Parra-Párraga, E. Espinosa-García","doi":"10.15446/cr.v8n1.90865","DOIUrl":"https://doi.org/10.15446/cr.v8n1.90865","url":null,"abstract":"Introduction: Hereditary spastic paraplegia (HSP) is the term for a group of neurological disorders characterized by progressive spasticity and muscle weakness in the lower limbs. Its etiology is genetic and has been associated with mutations in more than 60 genes. HSP is rare and may be useful in the differential diagnosis of cerebral palsy.\u0000Case presentation: 16-year-old male with a diagnosis of HSP due to mutation of the NIPA1 gene:c.316G>A (p. Gly106arg), which corresponds to HSP type 6 (SPG6). The patient presented with clinical signs of progressive upper motor neuron syndrome in the lower limbs, such as spasticity, hyperreflexia and paraparesis, associated with focal onset seizures diagnosed at age 11 and successfully treated with valproic acid. Spasticity treatment was complex and included oral baclofen, intraoperative botulinum toxin, physical therapy, and multilevel orthopedic surgery for the management of musculoskeletal deformities.\u0000Conclusion: This is a rare case of complex HSP, associated with epilepsy, due to the mutation of the NIPA1 gene (SPG6), the most common pathogenic variant within this type of mutation. The present case demonstrates the importance of making an early diagnosis of GSP6 to perform timely interventions in these patients, prevent complications, and avoid a higher level of disability.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72741735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment approach to a patient with catamenial epilepsy. Case report 双足癫痫患者的治疗方法。病例报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.91649

Mauricio Andrés Martínez Ramírez, Sandra Milena Sanchez Gutiérrez, Yuly Natalia Guzmán Yara, Karol Zeleny Pinzón Jaime, Silvia Carolina Rueda Cataño, Laura Fernanda Sarmiento Bocanegra, Luisa Cristina Sánchez Marín, Sara María Lasprilla Villalobos

{"title":"Treatment approach to a patient with catamenial epilepsy. Case report","authors":"Mauricio Andrés Martínez Ramírez, Sandra Milena Sanchez Gutiérrez, Yuly Natalia Guzmán Yara, Karol Zeleny Pinzón Jaime, Silvia Carolina Rueda Cataño, Laura Fernanda Sarmiento Bocanegra, Luisa Cristina Sánchez Marín, Sara María Lasprilla Villalobos","doi":"10.15446/cr.v8n1.91649","DOIUrl":"https://doi.org/10.15446/cr.v8n1.91649","url":null,"abstract":"Introduction: Catamenial epilepsy refers to the worsening or exacerbation of seizures due to hormonal changes during the menstrual cycle. It is thought to be secondary to the neuroactive properties of endogenous steroid hormones and the natural cyclic variation in their serum levels throughout the menstrual cycle.\u0000Case presentation: A 31-year-old female patient from Bogotá (Colombia) was admitted to the emergency department due to an episode of tonic-clonic seizure associated with the menstrual period. Since the onset of the seizures was related to menstruation (every 28 days), it was established that the patient had structural focal epilepsy with catamenial features. Advantages of medical vs. surgical treatment were discussed during a multidisciplinary medical board and it was decided to start pharmacological treatment with progestogens, which resulted in complete remission of the seizures as established during a follow-up visit.\u0000Conclusions: Catamenial epilepsy should be considered as a cause of epilepsy refractory to antiepileptic medications. Furthermore, it should be approached from a multidisciplinary perspective and its management should be focused on improving the patients’ quality of life.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87255418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pentalogy of Cantrell. A stillbirth case report 坎特雷尔五联症。1例死产病例报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.91323

Maribel Palencia Palacios, Blanca Viviana Fajardo Idrobo, López Mosquera López Mosquera, Jaime Antonio Álvarez Soler

{"title":"Pentalogy of Cantrell. A stillbirth case report","authors":"Maribel Palencia Palacios, Blanca Viviana Fajardo Idrobo, López Mosquera López Mosquera, Jaime Antonio Álvarez Soler","doi":"10.15446/cr.v8n1.91323","DOIUrl":"https://doi.org/10.15446/cr.v8n1.91323","url":null,"abstract":"Introduction: Pentalogy of Cantrell is a rare congenital disorder characterized by midline birth anomalies. Its embryological origins are related to anomalies of the abdominal wall that prevent the closure of the thorax. Its etiology is not yet clear, but it has been associated with a failure of migration of the lateral plate mesoderm to the midline.\u0000Case description: A stillbirth at 25.2 weeks of gestation diagnosed with pentalogy of Cantrell. The mother was a 14-year-old teenager with no relevant history of disease. An obstetric ultrasound was performed at 19 weeks of gestation and revealed findings suggestive of pentalogy of Cantrell. The mother was informed of the potential risks and future complications for the fetus, yet she chose to continue with the pregnancy. At 25.2 weeks of gestation, the mother went to the emergency department due to pain in the hypogastrium accompanied by moderate vaginal bleeding and absence of fetal activity. Once fetal death was confirmed by ultrasound, labor was induced, resulting in stillbirth with anencephaly, thoracic hypoplasia, gastroschisis, and eventration of the liver.\u0000Conclusions: Adequate antenatal care, including strict ultrasound follow-up, is essential to detect future complications in the fetus; to provide advice on possible malformations incompatible with life, such as pentalogy of Cantrell; and to determine the best therapeutic approach.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84796814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

De Garengeot’s hernia: case report 德·加朗热疝气1例报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.90041

Fabio Felipe Cortés-Díaz, Alejandro Vega-Molina, Kenndy Mawreny Arevalo-Pereira, Daniel Alfonso Fernandez-Sandoval

{"title":"De Garengeot’s hernia: case report","authors":"Fabio Felipe Cortés-Díaz, Alejandro Vega-Molina, Kenndy Mawreny Arevalo-Pereira, Daniel Alfonso Fernandez-Sandoval","doi":"10.15446/cr.v8n1.90041","DOIUrl":"https://doi.org/10.15446/cr.v8n1.90041","url":null,"abstract":"Introduction: De Garengeot hernia is an entity mainly diagnosed intraoperatively. It is more frequently observed in women and is defined as the presence of the vermiform appendix inside to femoral hernia. Most femoral hernias are identified based on clinical diagnosis, but diagnostic imaging is necessary for confirmation. Ultrasound, for example, is a valuable tool to characterize the anatomy of the hernia and its content, and to establish surgical planning.\u0000Case presentation: A 75-year-old woman attended the general surgery department of a high complexity hospital in Bogotá, Colombia, due to a painful mass in the right inguinal region. The initial ultrasound study showed a femoral hernia containing the incarcerated appendix and periappendiceal fluid in the hernial sac. The patient developed chronic appendiceal inflammation, so she underwent femoral hernia repair with mesh and appendectomy without complications, achieving a satisfactory recovery.\u0000Conclusion: Clinical examination may be sufficient to confirm the presence of a hernia in a large number of cases when the diagnostic approach involves the search of inguinal masses with pain. However, to facilitate surgical planning, diagnostic imaging, especially ultrasound with high resolution transducers, is the primary tool to characterize the type of hernia and the contents of the hernial sac.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76838024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic recurrent multifocal osteomyelitis, a rare disease. Case report 慢性复发性多灶性骨髓炎，罕见病。病例报告

Journal of cardiology case reports Pub Date : 2022-08-03 DOI: 10.15446/cr.v8n1.91304

Yazmin Paola Martinez Suarez, José Armando Amador Gutiérrez

{"title":"Chronic recurrent multifocal osteomyelitis, a rare disease. Case report","authors":"Yazmin Paola Martinez Suarez, José Armando Amador Gutiérrez","doi":"10.15446/cr.v8n1.91304","DOIUrl":"https://doi.org/10.15446/cr.v8n1.91304","url":null,"abstract":"Introduction: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare inflammatory bone disease usually observed in children and adolescents. It is caused by an imbalance between proinflammatory and anti-inflammatory factors. To establish its diagnosis, it is necessary to integrate clinical and laboratory elements that are typically aimed at ruling out other conditions, constituting a diagnosis of exclusion. Treatment is based on non-steroidal anti-inflammatory drugs and other drugs in specific cases.\u0000Case presentation: A 16-year-old female patient with a 1-year history of joint pain, especially in the knees, accompanied by signs of local inflammation was admitted to the emergency department of a quaternary care hospital due to a fever >38.5°, odynophagia, asthenia, and adynamia over the last two days. The patient underwent multiple extension studies, including laboratory, imaging and histopathological tests, which ruled out various etiologic causes. She received empirical antibiotic treatment without remission of symptoms, so a diagnosis of CRMO was finally established and outpatient treatment with non-steroidal anti-inflammatory drugs and corticosteroids was indicated, obtaining a favorable response.\u0000Conclusions: CRMO should be considered in children and adolescents with bone pain and a poorly defined clinical history with non-specific laboratory, imaging and histopathological findings. To date, little is known about CRMO, so it is necessary to carry out research and expand the knowledge related to this disease.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82653828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complex Management of AV Nodal Agent Toxicity in Patients with Cardiac Devices: Massive Calcium Channel Antagonist Overdose in a Patient with a Permanent Pacemaker 心脏装置患者房室结药物毒性的复杂管理:永久性起搏器患者大量钙通道拮抗剂过量

Journal of cardiology case reports Pub Date : 2022-01-27 DOI: 10.15761/jccr.1000175

Patric W Gibbons, Peter R Chai, T. Erickson

{"title":"Complex Management of AV Nodal Agent Toxicity in Patients with Cardiac Devices: Massive Calcium Channel Antagonist Overdose in a Patient with a Permanent Pacemaker","authors":"Patric W Gibbons, Peter R Chai, T. Erickson","doi":"10.15761/jccr.1000175","DOIUrl":"https://doi.org/10.15761/jccr.1000175","url":null,"abstract":"We present a unique case of a massive calcium channel antagonist overdose in a patient with a permanent pacemaker. Upon presentation after the acute overdose, the patient’s cardiac device was found to be pacing to an adequate rate (75 beats per minute) and she was admitted to the cardiac intensive care unit. Approximately 24 hours after her ingestion, she acutely decompensated and became hypotensive. The patient was started on infusions of norepinephrine, epinephrine, phenylephrine, and vasopressin. Her mean arterial pressure was unresponsive to multi-vasopressor therapy. She was then given a bolus of methylene blue and high-dose insulin euglycemic therapy. Despite these treatments, the patient remained hypotensive Therefore, intralipid emulsion therapy and IV epinephrine pushes were also administered. As a result of her shock and hemodynamic instability, her course was further complicated by hypoxemic respiratory failure for which she required ventilatory support and developed oliguric renal failure for which she was initiated on continuous veno-venous hemofiltration. This case emphasizes the challenges in managing complex physiology associated with nodal agent toxicity and is the first, to our knowledge, to describe management in a patient who already had a pacemaker, though it was ultimately ineffective in avoiding the patient’s profound decompensation.","PeriodicalId":73637,"journal":{"name":"Journal of cardiology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42500274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0