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Different Coagulation Markers as Predictors of Severity in Cancer Patients with COVID-19 Infection 不同凝血指标作为COVID-19感染癌症患者严重程度的预测指标
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079194
F. Alfraih, Mostafa F. Mohammed Saleh, A. Abdrabou, A. Haroon, K. AlSaleh, T. Owaidah
{"title":"Different Coagulation Markers as Predictors of Severity in Cancer Patients with COVID-19 Infection","authors":"F. Alfraih, Mostafa F. Mohammed Saleh, A. Abdrabou, A. Haroon, K. AlSaleh, T. Owaidah","doi":"10.26502/jcsct.5079194","DOIUrl":"https://doi.org/10.26502/jcsct.5079194","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal Intramedullary Ewing Sarcoma with Meningeal Carcinomatosis: A Complete Response to Chemotherapy and Neuroaxis Irradiation. Case Report and Review of Literature 脊髓尤文氏髓内肉瘤合并脑膜癌病:对化疗和神经轴照射的完全反应。病例报告及文献回顾
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079195
V. Albarrán, M. Villamayor, Ignacio Ruz, Jesús Chamorro, D. Rosero, J. Pozas, María San Román, P. A. Ballesteros, María Ángeles Vaz
{"title":"Spinal Intramedullary Ewing Sarcoma with Meningeal Carcinomatosis: A Complete Response to Chemotherapy and Neuroaxis Irradiation. Case Report and Review of Literature","authors":"V. Albarrán, M. Villamayor, Ignacio Ruz, Jesús Chamorro, D. Rosero, J. Pozas, María San Román, P. A. Ballesteros, María Ángeles Vaz","doi":"10.26502/jcsct.5079195","DOIUrl":"https://doi.org/10.26502/jcsct.5079195","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liquiritigenin Enhances the Inhibitory Effects of the Cholesterol Biosynthesis Inhibitor RO 48-8071 on Cell Viability in Ovarian-Cancer Cells in Vitro 利尿素增强胆固醇生物合成抑制剂RO 48-8071对卵巢癌细胞活力的体外抑制作用
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079207
Yayun Liang, Salman M Hyder
{"title":"Liquiritigenin Enhances the Inhibitory Effects of the Cholesterol Biosynthesis Inhibitor RO 48-8071 on Cell Viability in Ovarian-Cancer Cells in Vitro","authors":"Yayun Liang, Salman M Hyder","doi":"10.26502/jcsct.5079207","DOIUrl":"https://doi.org/10.26502/jcsct.5079207","url":null,"abstract":"Almost 25,000 new cases of epithelial ovarian cancer (EOC) are reported each year in the United States. Cancers of the ovary have poor prognosis due to drug resistance and metastasis, and have the highest mortality rate of all the known gynecological malignancies. Despite concerted efforts to develop new strategies for preventing and treating ovarian cancer, novel and more effective non-toxic therapies for ovarian cancer are urgently needed. Recent observations show that RO 48-8071 ([4’-[6-(Allylmethylamino)hexyloxy]-4-bromo-2’-fluorobenzophenone fumarate] [RO], a small-molecule inhibitor of the key cholesterol biosynthesis enzyme 2, 3-oxidosqualene cyclase, inhibits breast and prostate cancer cells. RO also induces the tumor-suppressor protein estrogen receptor (ER) β in both breast- and prostate-cancer cells, and also inhibits growth of ovarian-cancer cells both in vitro and in vivo. Extending upon these earlier studies, here we found that RO also induces ERβ expression in OVCAR-3 ovarian-cancer cells. Further, we demonstrated that treatment of two ovarian-cancer cell lines (OVCAR-3 and SK-OV-3) with liquiritigenin (LQ), a naturally occurring compound that is an ERβ agonist, reduced cell viability in vitro. When we treated OVCAR-3 and SK-OV-3 cells with RO, LQ, or RO + LQ, we observed that RO + LQ combination treatment synergistically reduced cell viability. Further in vivo studies examining the effects of RO + LQ combination treatment on EOC are warranted, as a means of exploring a potential new therapeutic approach to combat ovarian cancers with minimal toxicity.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung Hydatid Cysts in Children, Evaluation and Surgical Management 儿童肺包虫病的评估和外科治疗
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079189
Burkan Nasr, Anwar Al_junaeed, Ghaleb Al Sady, Ahmad Al Shehari, A. Amri, M. Issa, Abdulhakim Al Tamimi, Saeed Al Bahlooli, Mohammed Al_Sormi, Abdulfattah Altam, Yasser A Obadiel, M. Al-Shehari, Ali Hiddan.
{"title":"Lung Hydatid Cysts in Children, Evaluation and Surgical Management","authors":"Burkan Nasr, Anwar Al_junaeed, Ghaleb Al Sady, Ahmad Al Shehari, A. Amri, M. Issa, Abdulhakim Al Tamimi, Saeed Al Bahlooli, Mohammed Al_Sormi, Abdulfattah Altam, Yasser A Obadiel, M. Al-Shehari, Ali Hiddan.","doi":"10.26502/jcsct.5079189","DOIUrl":"https://doi.org/10.26502/jcsct.5079189","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewing Stereotactic Body Radiation Therapy Boost after Neoadjuvant Chemoradiation as an Alternative to Brachytherapy Boost for Locally Advanced Cervical Cancer 新辅助放化疗后立体定向体放射强化治疗作为局部晚期宫颈癌近距离强化治疗的替代方案
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079196
{"title":"Reviewing Stereotactic Body Radiation Therapy Boost after Neoadjuvant Chemoradiation as an Alternative to Brachytherapy Boost for Locally Advanced Cervical Cancer","authors":"","doi":"10.26502/jcsct.5079196","DOIUrl":"https://doi.org/10.26502/jcsct.5079196","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Experience of Palliative Care Patients Who Underwent Telemedicine in the State of Qatar during the COVID-19 Pandemic 卡塔尔国在2019冠状病毒病大流行期间接受远程医疗的姑息治疗患者的经历
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079201
A. Hassan, A. Allam, Saad Jobran Eziada, Hiba Elathir, Azar Saleeml, Sair Ibrahim, Zeinab Idris, Shaikhah Mohsen
{"title":"The Experience of Palliative Care Patients Who Underwent Telemedicine in the State of Qatar during the COVID-19 Pandemic","authors":"A. Hassan, A. Allam, Saad Jobran Eziada, Hiba Elathir, Azar Saleeml, Sair Ibrahim, Zeinab Idris, Shaikhah Mohsen","doi":"10.26502/jcsct.5079201","DOIUrl":"https://doi.org/10.26502/jcsct.5079201","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Quality of Life of Retinoblastoma Survivors: An Initial Exploration 研究视网膜母细胞瘤幸存者的生活质量:初步探索
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079202
Krishnasri Padamandala, Santosh G. Honavar, Rolika Bansal, Surya Durga Prasad M, Padmaja Gadiraju, Geeta K Vemuganti
{"title":"Investigating the Quality of Life of Retinoblastoma Survivors: An Initial Exploration","authors":"Krishnasri Padamandala, Santosh G. Honavar, Rolika Bansal, Surya Durga Prasad M, Padmaja Gadiraju, Geeta K Vemuganti","doi":"10.26502/jcsct.5079202","DOIUrl":"https://doi.org/10.26502/jcsct.5079202","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phosphatidylserine’s Exposure on Tumor Cells Determines a Tumor’s Microenvironment and Checkpoint Molecule Exposure, a Hypothesis 磷脂酰丝氨酸在肿瘤细胞上的暴露决定了肿瘤的微环境和检查点分子暴露，一个假设
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079190
James Randall Kennedy
{"title":"Phosphatidylserine’s Exposure on Tumor Cells Determines a Tumor’s Microenvironment and Checkpoint Molecule Exposure, a Hypothesis","authors":"James Randall Kennedy","doi":"10.26502/jcsct.5079190","DOIUrl":"https://doi.org/10.26502/jcsct.5079190","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast Lymphoma: A Report of 5 Cases and Literature Review 乳腺淋巴瘤5例报告并文献复习
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079200
Abidi Fethia, O. Chaibi, Riahi Nihed, Essghaier Sonia, Ksentini Feriel, A. Zidi
{"title":"Breast Lymphoma: A Report of 5 Cases and Literature Review","authors":"Abidi Fethia, O. Chaibi, Riahi Nihed, Essghaier Sonia, Ksentini Feriel, A. Zidi","doi":"10.26502/jcsct.5079200","DOIUrl":"https://doi.org/10.26502/jcsct.5079200","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concurrent Versus Sequential Chemoradiotherapy in Stage III Non-Small Cell Lung Cancer-A Comparative Study 同步与序贯放化疗治疗III期非小细胞肺癌的比较研究
Journal of cancer science and clinical therapeutics Pub Date : 2023-01-01 DOI: 10.26502/jcsct.5079209
Aditi Paul Chowdhury, Md. Ruhul Amin Bhuiyan, Md. Ershadul Haque, Abdul Mannan, Abdullah Al Mamun
{"title":"Concurrent Versus Sequential Chemoradiotherapy in Stage III Non-Small Cell Lung Cancer-A Comparative Study","authors":"Aditi Paul Chowdhury, Md. Ruhul Amin Bhuiyan, Md. Ershadul Haque, Abdul Mannan, Abdullah Al Mamun","doi":"10.26502/jcsct.5079209","DOIUrl":"https://doi.org/10.26502/jcsct.5079209","url":null,"abstract":"Background: Non-small cell Lung carcinoma is the most common carcinoma in both worldwide and Bangladesh. Most of them presents with locally advanced disease. Though Concurrent Chemoradiation (CCRT) is the standard approach, Sequential chemoradiotherapy (SCRT) can also be considered in stage III NSCLC. This study’s aim is to compare the local control and toxicity of CCRT and SCRT in stage III NSCLC.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136258916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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