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Journal of cancer immunology最新文献

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Cancer-Related Pain: Inside a New Dynamic Personalized Approach. A Narrative Review 癌症相关疼痛：一种新的动态个性化方法。叙事评论
Journal of cancer immunology Pub Date : 2022-04-01 DOI: 10.33696/cancerimmunol.4.060
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引用次数: 0
OGR1-a Novel Modulator Target of Tumor Immunotherapy 肿瘤免疫治疗的新调控靶点ogr1
Journal of cancer immunology Pub Date : 2022-04-01 DOI: 10.33696/cancerimmunol.4.062
{"title":"OGR1-a Novel Modulator Target of Tumor Immunotherapy","authors":"","doi":"10.33696/cancerimmunol.4.062","DOIUrl":"https://doi.org/10.33696/cancerimmunol.4.062","url":null,"abstract":"","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48176285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical, FDG-PET and Molecular Markers of Immune Checkpoint Inhibitor Response in Patients with Advanced Merkel Cell Carcinoma 晚期Merkel细胞癌患者免疫检查点抑制剂反应的临床、FDG-PET和分子标记
Journal of cancer immunology Pub Date : 2022-04-01 DOI: 10.33696/cancerimmunol.4.058
{"title":"Clinical, FDG-PET and Molecular Markers of Immune Checkpoint Inhibitor Response in Patients with Advanced Merkel Cell Carcinoma","authors":"","doi":"10.33696/cancerimmunol.4.058","DOIUrl":"https://doi.org/10.33696/cancerimmunol.4.058","url":null,"abstract":"","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44794864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
MEK Inhibition in KRAS Mutated NSCLC: Quo vadis? KRAS突变的NSCLC中MEK的抑制作用:是否有效?
Journal of cancer immunology Pub Date : 2022-04-01 DOI: 10.33696/cancerimmunol.4.059
{"title":"MEK Inhibition in KRAS Mutated NSCLC: Quo vadis?","authors":"","doi":"10.33696/cancerimmunol.4.059","DOIUrl":"https://doi.org/10.33696/cancerimmunol.4.059","url":null,"abstract":"","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41616265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Potential of Plant Virus Nanoparticles (PVNPs) in Anticancer Immunotherapies. 植物病毒纳米粒子 (PVNPs) 在抗癌免疫疗法中的新兴潜力。
Journal of cancer immunology Pub Date : 2022-01-01 DOI: 10.33696/cancerimmunol.4.061
Mehdi Shahgolzari, Steven Fiering
{"title":"Emerging Potential of Plant Virus Nanoparticles (PVNPs) in Anticancer Immunotherapies.","authors":"Mehdi Shahgolzari, Steven Fiering","doi":"10.33696/cancerimmunol.4.061","DOIUrl":"10.33696/cancerimmunol.4.061","url":null,"abstract":"<p><p>Cancer immunotherapies using plant virus nanoparticles (PVNPs) have achieved considerable success in preclinical studies. PVNP based nanoplatforms can be endogenous immune adjuvants and act as nanocarriers that stabilize and deliver cancer antigens and exogenous immune adjuvants. Although they do not infect mammalian cells, PVNPs are viruses and they are variably recognized by pathogen pattern recognition receptors (PRR), activate innate immune cells including antigen-presenting cells (APCs), and increase the expression of costimulatory molecules. Novel immunotherapy strategies use them as <i>in situ</i> vaccines (ISV) that can effectively inhibit tumor growth after intratumoral administration and generate expanded systemic antitumor immunity. PVNPs combined with other tumor immunotherapeutic options and other modalities of oncotherapy can improve both local and systemic anti-tumor immune responses. While not yet in clinical trials in humans, there is accelerating interest and research of the potential of PVNPs for ISV immune therapy for cancer. Thus, antitumor efficacy of PVNPs by themselves, or loaded with soluble toll-like receptor (TLR) agonists and/or cancer antigens, will likely enter human trials over the next few years and potentially contribute to next-generation antitumor immune-based therapies.</p>","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"4 1","pages":"22-29"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10117317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clutch Control: Changing the Speed and Direction of CAR-T Cell Therapy. 离合器控制：改变CAR-T细胞治疗的速度和方向。
Journal of cancer immunology Pub Date : 2022-01-01
Alberto Nobili, Aya Kobayashi, Patrick C Gedeon, Carl D Novina
{"title":"Clutch Control: Changing the Speed and Direction of CAR-T Cell Therapy.","authors":"Alberto Nobili, Aya Kobayashi, Patrick C Gedeon, Carl D Novina","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"4 2","pages":"52-59"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10838583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarkers of Pembrolizumab Efficacy in First-Line Advanced PD-L1 ?50% Non-Small Cell Lung Cancer Treatment Pembrolizumab对一线晚期PD-L1疗效的生物标志物？50%非小细胞肺癌癌症治疗
Journal of cancer immunology Pub Date : 2021-12-31 DOI: 10.33696/cancerimmunol.3.056
L. Cabezón-Gutiérrez, S. Custodio-Cabello, Magda Palka-Kotlowska, Sílvia, María Sanchez-Luis, P. Khosravi-Shahi
{"title":"Biomarkers of Pembrolizumab Efficacy in First-Line Advanced PD-L1 ?50% Non-Small Cell Lung Cancer Treatment","authors":"L. Cabezón-Gutiérrez, S. Custodio-Cabello, Magda Palka-Kotlowska, Sílvia, María Sanchez-Luis, P. Khosravi-Shahi","doi":"10.33696/cancerimmunol.3.056","DOIUrl":"https://doi.org/10.33696/cancerimmunol.3.056","url":null,"abstract":"Luis Cabezón-Gutiérrez Ph.D, M.D1, Sara Custodio-Cabello Ph.D, M.D1, Magda Palka-Kotlowska M.D1, Silvia María Sanchez-Luis M.D2, Parham Khosravi-Shahi Ph.D, M.D3 1Medical Oncology, Hospital Universitario de Torrejón. Universidad Francisco de Vitoria. Madrid, Spain 2Radiotherapy Oncology, Hospital Universitario de Torrejón. Madrid, Spain 3Medical Oncology, Hospital General Universitario Gregorio Marañón. Madrid, Spain *Correspondence should be addressed to Luis Cabezón-Gutiérrez; lcabezon@torrejonsalud.com","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45180243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunophenotypic Characterization by Flow Cytometry of Chronic Lymphoid Leukemia 慢性淋巴细胞白血病的流式细胞术免疫表型分析
Journal of cancer immunology Pub Date : 2021-12-31 DOI: 10.33696/cancerimmunol.3.057
Yenisey Triana Marrero, V. M. Suárez, Yaneisy Duarte Pérez, Gabriela Díaz Domínguez, Imilla, Casado Hernández, Elizabeth Hernández Ramos, R. M. Díaz, Consuelo Macías, Abraham
{"title":"Immunophenotypic Characterization by Flow Cytometry of Chronic Lymphoid Leukemia","authors":"Yenisey Triana Marrero, V. M. Suárez, Yaneisy Duarte Pérez, Gabriela Díaz Domínguez, Imilla, Casado Hernández, Elizabeth Hernández Ramos, R. M. Díaz, Consuelo Macías, Abraham","doi":"10.33696/cancerimmunol.3.057","DOIUrl":"https://doi.org/10.33696/cancerimmunol.3.057","url":null,"abstract":"Yenisey Triana Marrero1*, Vianed Marsán Suárez2, Yaneisy Duarte Pérez3, Gabriela Díaz Domínguez4, Imilla Casado Hernández5, Elizabeth Hernández Ramos6, Rosa María Lam Díaz7, Consuelo Milagros Macías Abraham8 1Dra. in Medicine, First degree specialist in MGI and Immunology, Assistant teacher, Associate Researcher 2Dra. in Medical Sciences, Second Degree Specialist in Immunology. Professor and Senior Researcher 3Dra. in Medicine, First degree specialist in MGI and Immunology, Assistant teacher 4Degree in Biochemistry and Molecular Biology, Associate Researcher 5MsC. Licensed in biology. Assistant Professor, Associate Researcher 6Degree in Biochemistry and Molecular Biology 7Dra. in Medicine, First degree specialist in Biostatistics, Assistant Researcher 8Dra. in Medical Sciences, Second Degree Specialist in Immunology, Professor and Senior Researcher 1-8Department of Immunology, “José Manuel BallesterSantovenia” Institute of Hematology and Immunology, Calle 19 e / 8 y 10. Postal code 10400, Vedado, Havana, Cuba *Correspondence should be addressed to Yenisey Triana Marrero; yeniseyt@infomed.sld.cu","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47641275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Humanized Chimeric Antigen Receptor (CAR) T cells 人源嵌合抗原受体(CAR) T细胞
Journal of cancer immunology Pub Date : 2021-12-31 DOI: 10.33696/cancerimmunol.3.055
Pouya Safarzadeh Kozani, Pooria Safarzadeh Kozani, R. O’Connor
{"title":"Humanized Chimeric Antigen Receptor (CAR) T cells","authors":"Pouya Safarzadeh Kozani, Pooria Safarzadeh Kozani, R. O’Connor","doi":"10.33696/cancerimmunol.3.055","DOIUrl":"https://doi.org/10.33696/cancerimmunol.3.055","url":null,"abstract":"T cells to unique antigens, the T-cell activation in a major complex chimeric as of the antigen recognition moiety to a single-chain variable fragment domain (scFv) and it the ζ chain of the TCR/CD3 modular recombinant, the intracellular CD3 ζ to T-cell activation following antigen engagement. it the origin of the chimeric antigen receptors (CARs) used clinically to of this very that CD3 with CD3 or growth factor receptor-bound protein optimal structural reconfigurations","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"3 1","pages":"183 - 187"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43558611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Therapeutic Monoclonal Antibodies: Future Prospectives 治疗性单克隆抗体：未来展望
Journal of cancer immunology Pub Date : 2021-12-31 DOI: 10.33696/cancerimmunol.3.054
Lobna Abdel Aziz Kilany, M. Aboulwafa, H. Zedan
{"title":"Therapeutic Monoclonal Antibodies: Future Prospectives","authors":"Lobna Abdel Aziz Kilany, M. Aboulwafa, H. Zedan","doi":"10.33696/cancerimmunol.3.054","DOIUrl":"https://doi.org/10.33696/cancerimmunol.3.054","url":null,"abstract":"Lobna Abdel Aziz Kilany1, Mohammad Mabrouk Aboulwafa2,3*, Hamdallah Hafez Zedan4 1Central administration of pharmaceuticals, Egyptian Drug Authority, 21 Abdel-Aziz Al souad St, Manial, Cairo, Egypt 2Faculty of Pharmacy, King Salman International University, Ras-Sedr, South Sinai, Egypt 3Department of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, African union organization Street, Abbassia, Cairo 11566, Egypt 4Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt *Correspondence should be addressed to Prof. Dr. Mohammad M. Aboulwafa; maboulwafa@yahoo.com, maboulwafa@pharma.asu. edu.eg, mohammad.aboulwafa@ksiu.edu.eg","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45039284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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