Journal of cancer immunology最新文献

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pMB FLASH - Status and Perspectives of Combining Proton Minibeam with FLASH Radiotherapy pMB FLASH-质子微束与FLASH联合放射治疗的现状与展望
Journal of cancer immunology Pub Date : 2019-10-22 DOI: 10.33696/cancerimmunol.1.003
Judith Reindl and Stefanie Girst
{"title":"pMB FLASH - Status and Perspectives of Combining Proton Minibeam with FLASH Radiotherapy","authors":"Judith Reindl and Stefanie Girst","doi":"10.33696/cancerimmunol.1.003","DOIUrl":"https://doi.org/10.33696/cancerimmunol.1.003","url":null,"abstract":"Proton minibeam radiotherapy (pMBRT) is an external beam radiotherapy method with reduced side effects by taking advantage of spatial fractionation in the normal tissue. Due to scattering, the delivered small beams widen in the tissue ensuring a homogeneous dose distribution in the tumor. In this review, the physical and biological principles regarding dose distribution and healing effects are explained. In the last decade, several preclinical studies have been conducted addressing normal tissue sparing and tumor control in-vitro and in-vivo, using human skin tissue and mouse or rat models. The major results acquired in these studies are summarized. A further newly emerging therapy method is FLASH radiotherapy, i.e. the treatment using ultra-high dose rates. The possibility of combining these methods in proton minibeam FLASH therapy (pMB FLASH) is worked out. Additionally, technical feasibility and limitations will be discussed by looking at simulations as well as preclinical studies and also pointing out new ways of delivering the desired tumor dose, such as interlacing. We will also highlight the opportunities that emerge regarding high dose radiation, hypofractionation and the combination with immunotherapy.","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44394762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Chimeric Antigen Receptor CAR NK Cells Emerging Immunotherapy for the Treatment of Cancer 嵌合抗原受体CAR - NK细胞用于治疗癌症的新兴免疫疗法
Journal of cancer immunology Pub Date : 2019-01-01 DOI: 10.33696/cancerimmunol.1.002
S. Deshmukh
{"title":"Chimeric Antigen Receptor CAR NK Cells Emerging Immunotherapy for the Treatment of Cancer","authors":"S. Deshmukh","doi":"10.33696/cancerimmunol.1.002","DOIUrl":"https://doi.org/10.33696/cancerimmunol.1.002","url":null,"abstract":"","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69669481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Symptom Clusters in Cancer Patients at First Presentation in Palliative Care Clinic as per Different Disease Groups 姑息治疗门诊首次就诊癌症患者不同疾病组症状群的患病率
Journal of cancer immunology Pub Date : 2019-01-01 DOI: 10.33696/cancerimmunol.1.001
Irum Ghafoor, Haroon Hafeez, Farhat Naz, M. Abubakar, A. Jamshed
{"title":"Prevalence of Symptom Clusters in Cancer Patients at First Presentation in Palliative Care Clinic as per Different Disease Groups","authors":"Irum Ghafoor, Haroon Hafeez, Farhat Naz, M. Abubakar, A. Jamshed","doi":"10.33696/cancerimmunol.1.001","DOIUrl":"https://doi.org/10.33696/cancerimmunol.1.001","url":null,"abstract":"Introduction: Cancer has its own disease burden and patients usually suffer from symptom clusters when they are referred for palliative treatment. Identification of symptom cluster trajectories will help clinician to take into account measures that can optimize quality of life of palliative patients. Therefore the aim of this paper is to determine the overall prevalence of symptoms and symptoms clusters in different disease groups according to etiology at the time of first visit to Palliative care clinic by using HIS Palliative First Assessment note indicating Edmonton symptom scale.","PeriodicalId":73633,"journal":{"name":"Journal of cancer immunology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69669463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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