Journal of cancer & allied specialties最新文献_第7页

Recent Changes to the Editorial Policies. 编辑策略的最新更改。

Journal of cancer & allied specialties Pub Date : 2020-01-06 eCollection Date: 2020-01-01 DOI: 10.37029/jcas.v6i1.325

Khawaja Shehryar Nasir

引用次数: 0

Tele-Oral Oncology: Reinvigorating Telemedicine in Oral Cancer Care. 口腔远程肿瘤：在口腔癌症护理中振兴远程医疗。

Journal of cancer & allied specialties Pub Date : 2020-01-06 eCollection Date: 2020-01-01 DOI: 10.37029/jcas.v6i1.335

Zaid H Khoury, Ahmed S Sultan

引用次数: 2

Outcomes of Advanced Retinoblastoma Treated with Local Salvage Treatment; a Retrospective Case Series. 局部抢救治疗晚期视网膜母细胞瘤的疗效；回顾性案例系列。

Journal of cancer & allied specialties Pub Date : 2020-01-06 eCollection Date: 2020-01-01 DOI: 10.37029/jcas.v6i1.283

Palwasha Rehman, Saadiya Javed Khan

{"title":"Outcomes of Advanced Retinoblastoma Treated with Local Salvage Treatment; a Retrospective Case Series.","authors":"Palwasha Rehman, Saadiya Javed Khan","doi":"10.37029/jcas.v6i1.283","DOIUrl":"10.37029/jcas.v6i1.283","url":null,"abstract":"Introduction: Retinoblastoma (RB) is the most common intraocular malignancy arising from the developing retina and occurs in approximately one of every 15,000-20,000 births. With the introduction of the intra-arterial chemotherapy (IAC), the 5-year overall survival of children with RB is 99%, though in low- and middle-income countries, it rarely exceeds 35% due to limited resources and lack of expertise. The aim of this study was to determine the outcome of local salvage in advanced RB.Materials and methods: A retrospective analysis was conducted on children diagnosed with advanced RB that had local salvage therapy along with systemic chemotherapy from January 2015 to January 2018 at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.Results: Fifteen patients were included in the study, among these 10 were male. The median age of presentation was 20 months (range 2-40 months). Among participants, 11 patients had bilateral RB. Fourteen patients received local control along with systemic chemotherapy. Relapse disease was seen in 12 patients and 2-year disease-free survival (DFS) was 20%.Conclusion: The results of the present study suggest that centres lacking the resources for IAC should treat advance cases of RB with an upfront or early enucleation.","PeriodicalId":73631,"journal":{"name":"Journal of cancer & allied specialties","volume":"6 1","pages":"e283"},"PeriodicalIF":0.0,"publicationDate":"2020-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3e/8c/JCAS-6-283.PMC10166347.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9841103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Notice of Retraction. 撤回通知。

Journal of cancer & allied specialties Pub Date : 2020-01-06 eCollection Date: 2020-01-01 DOI: 10.37029/jcas.v6i1.329

Khawaja Shehryar Nasir

引用次数: 0

Skin Metastasis in Breast Cancer Patients; a Case Series. 乳腺癌患者皮肤转移的研究a案例系列。

Journal of cancer & allied specialties Pub Date : 2020-01-01 DOI: 10.37029/jcas.v6i1.307

Sara Rehman, Muhammad Atif Naveed

{"title":"Skin Metastasis in Breast Cancer Patients; a Case Series.","authors":"Sara Rehman, Muhammad Atif Naveed","doi":"10.37029/jcas.v6i1.307","DOIUrl":"https://doi.org/10.37029/jcas.v6i1.307","url":null,"abstract":"Introduction: Breast cancer is the most common malignancy in women. It frequently metastasizes to bones, lungs and liver. Although rare, skin metastasis may also take place. It may also be the presenting feature of initial or recurrent breast cancer. The assessment of recurrent metastatic disease involving skin after mastectomy can be challenging because of the benign-appearing clinical presentation. The purpose of this case series was to explore the clinical and radiological presentation of skin metastasis in patients of breast cancer.Materials and methods: This is a retrospective case series of breast cancer patients with skin lesions on chest and abdomen at the time of initial presentation, or post-treatment such as, after mastectomy or breast conservation therapy; who underwent various radiological investigations including mammography, ultrasound scan, computed tomography (CT) scan and magnetic resonance imaging from 1 May 2018 to 30 September 2019 at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Pakistan.Results: A total of eight cases were identified, out of which seven were females. The most common presentation consisted of the presence of metastatic nodules which were seen in 62.5% (five out of eight) of the patients. Other features consisted of erythematous or plaque-like skin thickening on clinical examination, increased density with indistinct margins seen on a mammogram and diffuse oedematous changes in the skin with small irregular mass or infiltration into subcutaneous tissues were visualised on ultrasound and CT studies.Conclusion: Skin metastasis from breast cancer most commonly presents as nodules, although rarely they may present as plaques or diffuse skin thickening. Awareness of diverse manifestations of skin metastasis is of utmost importance in early diagnosis and management.","PeriodicalId":73631,"journal":{"name":"Journal of cancer & allied specialties","volume":"6 1","pages":"307"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.37029/jcas.v6i1.307","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9541329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE ROLE OF INTRAOPERATIVE FROZEN SECTION OF SENTINEL LYMPH NODES IN UPFRONT BREAST CONSERVATION CANCER SURGERY 术中前哨淋巴结冷冻切片在前期乳腺癌保乳手术中的作用

Journal of cancer & allied specialties Pub Date : 2019-06-30 DOI: 10.37029/JCAS.V5I2.227

R. Khan, A. Malik, S. Mohtasham, A. Khan, M. Parvaiz, A. Loya

{"title":"THE ROLE OF INTRAOPERATIVE FROZEN SECTION OF SENTINEL LYMPH NODES IN UPFRONT BREAST CONSERVATION CANCER SURGERY","authors":"R. Khan, A. Malik, S. Mohtasham, A. Khan, M. Parvaiz, A. Loya","doi":"10.37029/JCAS.V5I2.227","DOIUrl":"https://doi.org/10.37029/JCAS.V5I2.227","url":null,"abstract":"Objective: Sentinel lymph node biopsy is the standard of care in clinically negative axilla in breast cancer patients for which frozen section (FS) is routinely performed intraoperatively. The objective of this study was to justify the use of FS in terms of number of tests performed and their impact on decision-making and cost saving. Materials and Methods: We retrospectively reviewed our prospectively maintained data from January 2014 to January 2018 for intraoperative FS in upfront breast conservation surgery patients. Results: A total of 357 patients were studied. All were female. Median age was 50 years (24–84). Mean tumour size was 29.11 mm. Numbers of sentinel lymph nodes identified were 1 in 50 (14.2%) patients, 2 in 121 (33.89%) patients and ≥3 in 186 (52%) patients. Number of positive sentinel lymph nodes was 0 in 264 (73.9%) patients, 1 in 62 (17.4%) patients, 2 in 20 (5.6%) patients and ≥3 in 11 (3.08%) patients. Axillary lymph node dissection (ALND) was offered to 30 (8.4%) patients as per the American College of Surgeons Oncology Group Z0011. The results for ALND showed that only 8 (2.3%) out of 30 patients had positive nodes identified in the additional axillary nodes dissected. Sensitivity of FS was 97% and specificity was 98.86%. False-negative rate was 3.22%. Conclusion: Intraoperative FS can be safely omitted in early breast cancer patients undergoing upfront breast conservation cancer surgery due to high sensitivity and specificity leading to low false-negative rates. ALND can be performed as a second operation as warranted only in a minority of patients. Key words: American College of Surgeons Oncology Group Z0011 trial, axillary lymph node dissection, intraoperative frozen section, sentinel lymph node biopsy","PeriodicalId":73631,"journal":{"name":"Journal of cancer & allied specialties","volume":"188 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78326658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SOLITARY FIBROUS TUMOR OF BREAST 乳腺孤立性纤维性肿瘤

Journal of cancer & allied specialties Pub Date : 2019-06-30 DOI: 10.37029/JCAS.V5I2.231

S. Noor, N. Akhtar, Usman Hassan, M. Hameed

引用次数: 0

RUPTURED INTRACRANIAL DERMOID CYST 破裂的颅内皮样囊肿

Journal of cancer & allied specialties Pub Date : 2019-06-30 DOI: 10.37029/JCAS.V5I2.223

Taimoor Ali Tariq, Pir Abdul Ahad Aziz Qureshi, Muhammad Talha Yaseen Kaimkhani

引用次数: 0

EWING’S SARCOMA: APPROACHING CENTURY SINCE THIS BONE CANCER MADE NEWS 尤文氏肉瘤:近一个世纪以来，这种骨癌成为新闻

Journal of cancer & allied specialties Pub Date : 2019-06-30 DOI: 10.37029/JCAS.V5I2.263

Z. Fadoo, Mir Ibrahim Sajid

引用次数: 0

CENTRAL NERVOUS SYSTEM RELAPSE OF MULTIPLE MYELOMA 中枢神经系统多发性骨髓瘤复发

Journal of cancer & allied specialties Pub Date : 2019-03-31 DOI: 10.37029/JCAS.V5I1.199

M. Qubtia, M. Nasir, Memoona Mian, A. Hameed

{"title":"CENTRAL NERVOUS SYSTEM RELAPSE OF MULTIPLE MYELOMA","authors":"M. Qubtia, M. Nasir, Memoona Mian, A. Hameed","doi":"10.37029/JCAS.V5I1.199","DOIUrl":"https://doi.org/10.37029/JCAS.V5I1.199","url":null,"abstract":"Multiple myeloma (MM) is a plasma cell disorder primarily involving bone marrow. Extramedullary involvement is less common, with central nervous system (CNS) myelomatosis being a rare entity and such presentation carries extremely dismal prognosis. We present case of a 40 years old male with MM who was initially treated with 6 cycles of Cyclophosphamide, Thalidomide and Dexamethasone resulting in complete response. 2 years later he presented with CNS myelomatosis and scrotal involvement and was initially treated with Bortezomib and dexamethasone, cranial irradiation and intrathecal Methorexate, Cytarabine, Hydrocortisone (TRIO IT), along with radical orchiectomy and testicular radiation during the course of treatment. However, after initial response his disease showed clinical and radiological progression after 4 months of therapy. He was switched to high dose Methotrexate (HD-MTX) with TRIOITand later Lenalidamide and dexamethasone (Len/dex) was added to the above regimen. He continued to show good clinical response but his cytology remained persistently positive, therefore, HD-MTX was discontinued in the later course of treatment. Subsequently he was started on best supportive care only, when his neurological status deteriorated further. He survived almost 9 months after a diagnosis of CNS myelomatosis. Patients with multiple myeloma, presenting with neurological symptoms should always be investigated for the possibility of CNS MM. CNS relapse is a fatal disease with poor prognosis. Recommended treatment must include a systemic anti-MM regimen that crosses the BBB (ideally Immunomodulatory drugs (IMiDs) IMiDs-dexamethasone based therapy), CNS irradiation and intrathecal chemotherapy.Key words: Multiple myeloma, central nervous system myelomatosis, therapy","PeriodicalId":73631,"journal":{"name":"Journal of cancer & allied specialties","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91298430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0