JMM case reportsPub Date : 2017-09-18eCollection Date: 2017-09-01DOI: 10.1099/jmmcr.0.005115
Giulia Ciceri, Maria Gori, Silvia Bianchi, Giovanni Corrado, Paolo Panisi, Angela Papa, Elisabetta Tanzi, Mirella Pontello
{"title":"Molecular evidence of <i>Listeria monocytogenes</i> infection relapse in a severe case of endocarditis.","authors":"Giulia Ciceri, Maria Gori, Silvia Bianchi, Giovanni Corrado, Paolo Panisi, Angela Papa, Elisabetta Tanzi, Mirella Pontello","doi":"10.1099/jmmcr.0.005115","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005115","url":null,"abstract":"<p><p><b>Introduction.</b> Endocarditis is a rare complication of bacteraemia due to <i>Listeria monocytogenes</i> and is characterized by a high fatality rate (37-50 %). Recurrent infection by <i>Listeria monocytogenes</i> occurs even more rarely. <b>Case presentation.</b> We report a case of recurrent <i>Listeria monocytogenes</i> infection that resulted in severe endocarditis in a 66-year-old patient with an aortic valve prosthesis. Relapse was confirmed by pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST). <b>Conclusion.</b> Our case highlights that the molecular subtyping approach is an important tool for the detection of microbial reinfections and for the support of clinical diagnosis.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 9","pages":"e005115"},"PeriodicalIF":0.0,"publicationDate":"2017-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35233199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JMM case reportsPub Date : 2017-09-18eCollection Date: 2017-09-01DOI: 10.1099/jmmcr.0.005112
Carolyn A Hilliard, Jad El Masri, Michihiko Goto
{"title":"<i>Staphylococcus caprae</i> bacteraemia and native bone infection complicated by therapeutic failure and elevated MIC: a case report.","authors":"Carolyn A Hilliard, Jad El Masri, Michihiko Goto","doi":"10.1099/jmmcr.0.005112","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005112","url":null,"abstract":"<p><p><b>Introduction.</b><i>Staphylococcus caprae</i> is a coagulase-negative staphylococcus that has been reported in several cases as a human pathogen. However, it has rarely been reported as pathogen in native bone. Furthermore, the reported MIC levels noted in the literature for vancomycin were <2 µg ml<sup>-</sup><sup>1</sup>making vancomycin a first line choice for infected patients. <b>Case presentation.</b> We report a case of <i>Staphylococcus caprae</i> causing osteomyelitis of the lumbar spine and bacteraemia and resulting in sepsis and ultimately the demise of a patient despite appropriate prolonged antibiotic therapy. <b>Conclusion.</b><i>Staphylococcus caprae</i> has been reported as a human pathogen since 1983 when it was discovered. We report a case involving native bone infection which is rare in the absence of mechanical hardware. Furthermore, this strain had an elevated MIC for vancomycin which has not been reported in the literature.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 9","pages":"e005112"},"PeriodicalIF":0.0,"publicationDate":"2017-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1099/jmmcr.0.005112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35233197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JMM case reportsPub Date : 2017-09-18eCollection Date: 2017-09-01DOI: 10.1099/jmmcr.0.005116
Olivier Lheureux, Isabel Montesinos, Olivier Taton, Martine Antoine, Jean-Charles Preiser, Joelle Nortier, Jacques Creteur, Frederique Jacobs, David Grimaldi
{"title":"False-positive galactomannan assay in broncho-alveolar lavage after enteral nutrition solution inhalation: a case report.","authors":"Olivier Lheureux, Isabel Montesinos, Olivier Taton, Martine Antoine, Jean-Charles Preiser, Joelle Nortier, Jacques Creteur, Frederique Jacobs, David Grimaldi","doi":"10.1099/jmmcr.0.005116","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005116","url":null,"abstract":"<p><p><b>Introduction.</b> Diagnosis of invasive aspergillosis is challenging and the gold standard for definite diagnosis remains histopathological tissue examination. However, invasive procedures such as lung biopsy are often not feasible in critically ill patients. The detection of fungal cell wall components like <i>Aspergillus</i> galactomannan in broncho-alveolar lavage remains a key component of the diagnostic procedure. False-positive of the <i>Aspergillus</i> galactomannan assay is not frequent. <b>Case presentation.</b> We report a case of positive galactomannan in broncho-alveolar lavage fluid after enteral nutrition aspiration without signs of invasive aspergillosis. Galactomannan was positive in the enteral nutrition solution. <b>Conclusion.</b> Physicians should be aware of this previously unrecognized cause of false-positive galactomannan in broncho-alveolar fluid which can result in unnecessary treatments.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 9","pages":"e005116"},"PeriodicalIF":0.0,"publicationDate":"2017-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35233200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Gordonia</i> sternal wound infection treated with ceftaroline: case report and literature review.","authors":"Kevan Akrami, Joelle Coletta, Sanjay Mehta, Joshua Fierer","doi":"10.1099/jmmcr.0.005113","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005113","url":null,"abstract":"<p><p><b>Introduction.</b> Case reports have emerged with identification of <i>Gordonia bronchialis</i> infections including sternal wound infections and foreign bodies such as central lines and shunts. <b>Case presentation.</b> We present a case that demonstrates the need to consider <i>Gordonia</i> infection as a cause of sternal wound infection and highlights the utility of novel diagnostics to aid in the identification of unusual pathogens that can cause post-operative infections. We report here the first successful use of ceftaroline for treatment of a <i>G. bronchialis</i> sternal wound infection. <b>Conclusion.</b> There are only case reports and <i>in vitro</i> assays to date to guide treatment of this infection, and we now add ceftaroline as a new drug to consider, though adequate surgical debridement is paramount.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 9","pages":"e005113"},"PeriodicalIF":0.0,"publicationDate":"2017-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35233198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Vibrio furnissii</i>, an emerging pathogen causing acute gastroenteritis: a Case Report.","authors":"Mamatha Ballal, Vignesh Shetty, Sohan Rodney Bangera, Mukhyaprana Prabhu, Shashikiran Umakanth","doi":"10.1099/jmmcr.0.005111","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005111","url":null,"abstract":"<p><p><b>Introduction.</b><i>Vibrio furnissii</i> is a motile, Gram-negative, oxidase-positive, halophilic bacteria first defined in 1977. It is ubiquitously present in marine environments and is one of the 11 non-cholera <i>Vibrio</i> species pathogenic in humans, which can lead to human gastroenteritis and extra-intestinal manifestations. <b>Case presentation.</b> A 73-year-old female patient was admitted to the hospital with acute gastroenteritis after consumption of seafood, which later by microbiological investigations was confirmed as <i>Vibrio furnissii</i>, a member of the family <i>Vibrionaceae</i>. The patient was treated with oral doxycycline and ciprofloxacin. <b>Conclusion.</b><i>V. furnissii</i>, an emerging pathogen known for quite some time as an aetiological agent responsible, for acute gastroenteritis cases yet to get more clinical attention. Descriptions of putative virulence factors of this pathogen are limited, and in-depth studies on the pathogenesis of <i>V. furnissii</i> need to be established.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"4 9","pages":"e005111"},"PeriodicalIF":0.0,"publicationDate":"2017-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35233196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neck abscess due to <i>Salmonella</i> Choleraesuis: case study and literature review.","authors":"Ryoji Sugimoto, Hirotaka Suzuki, Takahito Nei, Ayaka Tashiro, Yohei Washio, Kazunari Sonobe, Yuzo Nakamura, Nozomu Wakayama, Shunta Inai, Hidemasa Izumiya","doi":"10.1099/jmmcr.0.005109","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005109","url":null,"abstract":"<p><p><b>Introduction.</b> We herein describe a case with a neck abscess due to non-typhoidal <i>Salmonella</i> (NTS). NTS habitually reside in our environment and colonize all animals including mammals. Colonizations of pigs, chickens, cows and sheep are important because food poisoning episodes in human are often associated with meat. Extra-intestinal infection due to NTS has numerous presentations and complications, with aortic aneurysms being common. <b>Case presentation.</b> A 26-year-old Japanese male complaining of left-sided neck swelling was referred to our hospital for a suspected deep neck abscess. An enhanced computed tomography scan of the neck revealed a low density lesion in the left-sided deep neck area, and consequently the patient underwent urgent incision and drainage. After this urgent operation, <i>Salmonella</i> Choleraesuis was isolated from a greyish-white abscess. The patient ultimately recovered with antimicrobial administration, though re-incision for lymphadenectomy was necessary. The neck abscess may have developed because he had eaten raw meat. Furthermore, untreated diabetes mellitus was diagnosed at presentation. <b>Conclusion.</b><i>Salmonella enterica</i> serovar Choleraesuis infections are rare in Japan. NTS are generally recognized as important pathogens in food poisoning globally, and attention is required to avoid the development of extra-intestinal infections. In Japan, the increasing lifestyle diversity in recent years highlights the importance of recognizing rare infections.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":" ","pages":"e005109"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1099/jmmcr.0.005109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35507566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JMM case reportsPub Date : 2017-09-01eCollection Date: 2017-08-01DOI: 10.1099/jmmcr.0.005108
Sarah Baker, Rebecca Allyn
{"title":"Lytic lesions: looking lethal but leaving room for a simple cure? A case of <i>Veillonella</i> spinal osteomyelitis.","authors":"Sarah Baker, Rebecca Allyn","doi":"10.1099/jmmcr.0.005108","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005108","url":null,"abstract":"<p><p><b>Introduction.</b> Diagnosing clinically significant infection caused by <i>Veillonella</i> species can be a challenge. <i>Veillonella</i> species are usually found in polymicrobial processes and are often regarded as a contaminant. Additionally, they are slow to grow in culture and this can lead to a delay in diagnosis or a missed diagnosis. <i>Veillonella</i> species rarely cause serious infections, but have been found to cause bacteraemia and osteomyelitis. <b>Case presentation.</b> A 67-year-old man with a history of treated prostate cancer presented with 2 weeks of progressive lower back pain and weakness. He had no signs or symptoms of active infection. He was found to have multiple lytic lesions in his lumbar spine that were initially suspected to be secondary to metastatic cancer. However, tissue and blood cultures were ultimately consistent with infection by <i>Veillonella</i> species. <b>Conclusion.</b> This case report highlights the fact that uncommon illnesses can often present like common disease processes. Because of the radiological appearance of the patient's lesions and his lack of infectious symptoms, a diagnosis of metastatic cancer was initially thought to be likely. Relying on the pathology and culture data, and waiting on the initiation of antimicrobials until the diagnosis was accurately established, were important factors in diagnosing and treating this infection. <i>Veillonella</i> species can be true pathogens when found in isolation and associated with bacteraemia. Additionally, they can cause an indolent infection that can lead to osteomyelitis. Failure to accurately diagnose this infection in a timely manner would have led to ongoing debility and diagnostic uncertainty for this patient.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":" ","pages":"e005108"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35507565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The first fatal case of <i>Corynebacterium ulcerans</i> infection in Japan.","authors":"Ken Otsuji, Kazumasa Fukuda, Takeru Endo, Satoko Shimizu, Nobuya Harayama, Midori Ogawa, Akihiko Yamamoto, Kaoru Umeda, Toshiyuki Umata, Hiroyuki Seki, Masaaki Iwaki, Masayuki Kamochi, Mitsumasa Saito","doi":"10.1099/jmmcr.0.005106","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005106","url":null,"abstract":"<p><p><b>Introduction.</b><i>Corynebacterium ulcerans</i> (<i>C. ulcerans</i>) is a zoonotic pathogen that occasionally causes diphtheria-like symptoms in humans. Cases of <i>C. ulcerans</i> infection have been increasing in recent years, and <i>C. ulcerans</i> has been recognized as an emerging pathogen. <b>Case presentation.</b> Here we report a case of asphyxia death due to pseudomembrane caused by diphtheria toxin (DT)-producing <i>C. ulcerans.</i> This is, to our knowledge, the first fatal case of <i>C. ulcerans</i> infection in Japan. A strain of <i>C. ulcerans</i> was obtained from the patient's pet cat and was confirmed to be identical to the patient's isolate by sequencing of the 16S rRNA gene and the DT gene, by pulsed-field gel electrophoresis (PFGE) and by ribotyping. In the same way, it was revealed that the isolate in this case belonged to the same molecular type as the <i>C. ulcerans</i> 0102 isolated from the first case in Japan in a distant prefecture 15 years earlier, in 2001. <b>Conclusion.</b> DT-producing <i>C. ulcerans</i> can be contracted from a companion animal and causes human death if the appropriate treatment is delayed. The finding indicates that this molecular type of virulent <i>C. ulcerans</i> is currently widespread in Japan.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":" ","pages":"e005106"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1099/jmmcr.0.005106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35507564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JMM case reportsPub Date : 2017-08-08eCollection Date: 2017-08-01DOI: 10.1099/jmmcr.0.005104
Milo Cullinan, Michael Clarke, Tim Dallman, Steven Peart, Deborah Wilson, Daniel Weiand
{"title":"<i>Salmonella</i> Typhimurium gastroenteritis leading to chronic prosthetic vascular graft infection.","authors":"Milo Cullinan, Michael Clarke, Tim Dallman, Steven Peart, Deborah Wilson, Daniel Weiand","doi":"10.1099/jmmcr.0.005104","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005104","url":null,"abstract":"<p><p><b>Introduction.</b> It is estimated up to 6 % of prosthetic vascular grafts become infected. <i>Staphylococcus aureus</i> is predominant in early infection and coagulase-negative staphylococci are predominant in late infections. <i>Enterobacteriaceae</i> cause 14-40 % of prosthetic vascular graft infections. This is, to our knowledge the first reported case of <i>Salmonella</i> gastroenteritis causing chronic prosthetic vascular graft infection (PVGI). <b>Case presentation.</b> A 57 years old lady presented with signs and symptoms of prosthetic vascular graft infection. Three years earlier, she had undergone a prosthetic axillo-femoral bypass graft for critical limb ischaemia. The infected prosthetic vascular graft was removed and <i>Salmonella</i> Typhimurium was isolated on culture. In the intervening period, <i>Salmonella</i> Typhimurium was isolated from a faecal specimen, collected during an episode of acute gastroenteritis. Whole-genome sequencing (WGS) showed that the respective <i>Salmonella</i> Typhimurium isolates differed by only a single nucleotide polymorphism (SNP). <i>Salmonella</i> Typhimurium was not isolated on culture of a faecal specimen collected five days following cessation of antimicrobial therapy. Six months after removal of the prosthetic graft, the patient remains under follow-up for her peripheral vascular disease, which currently requires no further surgical intervention. <b>Conclusion.</b> This case has clear implications for the management of chronic PVGI. It is vital to collect high-quality surgical specimens for microbiological analysis and empirical choices of antibiotics are unlikely to cover all potential pathogens. It may also be prudent to enquire about a history of acute gastroenteritis when assessing patients presenting with chronic PVGI.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":" ","pages":"e005104"},"PeriodicalIF":0.0,"publicationDate":"2017-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35507562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JMM case reportsPub Date : 2017-08-08eCollection Date: 2017-08-01DOI: 10.1099/jmmcr.0.005105
Jiasian Teh, Mark Quinlan, Damien Bolton
{"title":"<i>Salmonella</i> Oranienburg haemorrhagic cystitis in an immunocompetent young male.","authors":"Jiasian Teh, Mark Quinlan, Damien Bolton","doi":"10.1099/jmmcr.0.005105","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005105","url":null,"abstract":"<p><p><b>Introduction.</b> Non-typhoidal salmonella (NTS) bacteriuria is extremely rare. Haemorrhagic cystitis is defined by urinary symptoms including haematuria, frequency, urgency and dysuria. Reports of haemorrhagic cystitis caused by NTS are exceptionally uncommon, especially in immunocompetent, young, male patients. <b>Case presentation.</b> A 27-year-old male with no past medical history presented to the Emergency Department with a 24 h history of visible haematuria having returned five days earlier from a five month trip across South America. He also reported one week of suprapubic pain with associated dysuria, frequency, difficulty voiding and fevers. A non-contrast abdominal and pelvic CT scan showed a grossly thick-walled bladder with marked peri-vesical stranding, strongly suggestive of cystitis, with an unremarkable appearance of the remainder of the urinary tract. Urine culture at presentation subsequently grew <i>Salmonella</i> Oranienburg. The patient reported total symptomatic relief following just one week of oral antibiotics with no recurrence to date. <b>Conclusion.</b> NTS urinary tract infection (UTI), especially in healthy young people, is very rare. In such cases, the existence of underlying diseases must be considered, especially diabetes mellitus, urological abnormalities and immunosuppression. However, a diagnosis of NTS UTI should also be among the differentials in those presenting with acute urinary symptoms preceded by gastrointestinal upset, especially following travel in underdeveloped countries. Antibiotic therapy is invariably indicated and close follow-up is warranted due to the risk of several potentially serious complications.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":" ","pages":"e005105"},"PeriodicalIF":0.0,"publicationDate":"2017-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35507563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}