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OIL OR FLAXSEED FLOUR REDUCES PANCREATIC ISLET AREA BUT DOES NOT AFFECT SERUM INSULIN, AT WEANING, IN MALE WISTAR RATS 在雄性wistar大鼠断奶时,油或亚麻籽粉可减少胰岛面积,但不影响血清胰岛素
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.4
A. D'Avila Pereira, D. Cavalcante Ribeiro, A. de Sousa dos Santos, B. Ferolla da Camara Boueri, C. Ribeiro Pessanha, M. Duque Coutinho de Abreu, L. Pessoa Rozeno, C. Cristina Alves do Nascimento-Saba, L. Guillermo Coca Velarde, C. A. Soares da Costa, G. Teles Boaventura
{"title":"OIL OR FLAXSEED FLOUR REDUCES PANCREATIC ISLET AREA BUT DOES NOT AFFECT SERUM INSULIN, AT WEANING, IN MALE WISTAR RATS","authors":"A. D'Avila Pereira, D. Cavalcante Ribeiro, A. de Sousa dos Santos, B. Ferolla da Camara Boueri, C. Ribeiro Pessanha, M. Duque Coutinho de Abreu, L. Pessoa Rozeno, C. Cristina Alves do Nascimento-Saba, L. Guillermo Coca Velarde, C. A. Soares da Costa, G. Teles Boaventura","doi":"10.14283/jarcp.2018.4","DOIUrl":"https://doi.org/10.14283/jarcp.2018.4","url":null,"abstract":"The aim of the present study evaluated the influence of oil or flaxseed flour in pancreas morphology of pups, whose mothers were fed with oil or flaxseed flour during lactation, at weaning. After birth, the lactating rat males were randomly assigned: control (C, n=12 pups), flaxseed oil (FO, n=12 pups) and flaxseed flour (FF, n=12). At 21 days, the pups were weaning and anesthetized. Body mass, length, serum glucose, insulin, pancreas mass and pancreatic islet area were assessed. FO and FF showed higher (p<0.05) mass and length and lower glucose (p<0.05) when compared with C. Insulin (p=0.094) and pancreas mass (p=0.054) not differ between groups. FO and FF showed lower (p<0.05) pancreatic islet area when compared with C. A fed with FO or FF, during lactation may improve function pancreatic, as insulin sensitivity. These findings emphasize that oil or flaxseed flour during lactation may improve pancreatic function in early life.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66885326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NUTRITIONAL AND NONNUTRITIONAL FACTORS WITH POSITIVE AND NEGATIVE EFFECTS ON THE EYE HEALTH BASED ON IRANIAN TRADITIONAL MEDICINE 根据伊朗传统医学,对眼睛健康有积极和消极影响的营养和非营养因素
JAR life Pub Date : 2018-01-01 DOI: 10.14283/JARCP.2018.1
S. Parvinroo
{"title":"NUTRITIONAL AND NONNUTRITIONAL FACTORS WITH POSITIVE AND NEGATIVE EFFECTS ON THE EYE HEALTH BASED ON IRANIAN TRADITIONAL MEDICINE","authors":"S. Parvinroo","doi":"10.14283/JARCP.2018.1","DOIUrl":"https://doi.org/10.14283/JARCP.2018.1","url":null,"abstract":"In Iranian Traditional Medicine (ITM), physicians considered health preservation as a main duty. Their recommendations have been proposed in order to keep the organs and the whole body healthy, considering useful and risk factors. The aim of this manuscript is to introduce some recommendations for maintaining eye healthy based on ITM literature in two different parts of nutritional and nonnutritional sections.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66884071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DECREASING LEVELS OF SPORACETIGENIUM CORRELATE WITH IMPROVED DIABETIC PARAMETERS IN HEALTHY ADULTS CONSUMING MSPREBIOTIC® DIGESTION RESISTANT STARCH 服用抗消化淀粉的健康成人中,孢子菌原水平的降低与糖尿病参数的改善相关
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.28
J. Bush, M. Alfa
{"title":"DECREASING LEVELS OF SPORACETIGENIUM CORRELATE WITH IMPROVED DIABETIC PARAMETERS IN HEALTHY ADULTS CONSUMING MSPREBIOTIC® DIGESTION RESISTANT STARCH","authors":"J. Bush, M. Alfa","doi":"10.14283/jarcp.2018.28","DOIUrl":"https://doi.org/10.14283/jarcp.2018.28","url":null,"abstract":"","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66885241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
CHOLINE, SLEEP DISTURBANCES, AND ALZHEIMER’S DISEASE 胆碱,睡眠障碍和老年痴呆症
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.17
V. Pak, S. Newton
{"title":"CHOLINE, SLEEP DISTURBANCES, AND ALZHEIMER’S DISEASE","authors":"V. Pak, S. Newton","doi":"10.14283/jarcp.2018.17","DOIUrl":"https://doi.org/10.14283/jarcp.2018.17","url":null,"abstract":"Existing studies identify a possible link between choline, sleep disturbance, and Alzheimer’s disease, however further exploration is needed to determine the nature of this association. As the precursor to the neurotransmitter acetylcholine, choline plays an integral role in several neuronal processes, including some responsible for memory and learning. Decreased cholinergic neuronal activity is associated with brain abnormalities consistent with Alzheimer’s disease, an aging disease that disproportionately affects the elderly, and is believed to contribute to the cognitive decline experienced by Alzheimer’s disease patients, however the mechanism for this is not well understood. In this narrative review, we explore the associations between sleep disturbances, choline and the cholinergic pathway, and Alzheimer’s disease. Current research shows that the connection between sleep disturbances, choline, and Alzheimer’s disease is worth exploring in greater depth. In this review, we demonstrate there is a need for further studies to understand the mechanism through which inadequate sleep may impair the cholinergic pathway in order to guide targeted treatments for Alzheimer’s disease.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66884597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DENTITION AND MALNUTRITION RISK IN COMMUNITYDWELLING OLDER ADULTS 社区居住老年人的牙齿和营养不良风险
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.19
R. Zelig, L. Byham-Gray, S. Singer, E. Hoskin, A. Marcus, G. Verdino, D. Radler, R. Touger-Decker
{"title":"DENTITION AND MALNUTRITION RISK IN COMMUNITYDWELLING OLDER ADULTS","authors":"R. Zelig, L. Byham-Gray, S. Singer, E. Hoskin, A. Marcus, G. Verdino, D. Radler, R. Touger-Decker","doi":"10.14283/jarcp.2018.19","DOIUrl":"https://doi.org/10.14283/jarcp.2018.19","url":null,"abstract":"Background and Objective: Older adults are at risk for both impaired oral health and suboptimal nutritional status. The objective of this study was to explore the relationships between malnutrition risk and missing teeth in community-dwelling older adults. Design: This was a retrospective cross-sectional analysis of data obtained from the electronic health records of 107 patients aged 65 and older who attended an urban northeast US dental school clinic between June 1, 2015 and July 15, 2016. Odontograms and radiographs were used to identify teeth numbers and locations; malnutrition risk was calculated using the Self-Mini Nutritional Assessment (Self-MNA). Relationships between numbers of teeth and malnutrition risk were assessed using bivariate logistic regression. Results: Participants (N=107) were 72.6 years (SD=5.6) of age; 50.5% were female. Mean Self-MNA score was 12.3 (SD=2.0) reflective of normal nutrition status; 20.6% were at risk for malnutrition, 4.7% were malnourished. Greater than 87% were partially or completely edentulous. Those with 10-19 teeth had lower Self-MNA scores (mean=11.6, SD=2.5) than those with 0-9 teeth (mean=12.7, SD=1.3) or 20 or more teeth (mean=12.6, SD=1.8) and had an increased risk for malnutrition (OR=2.5, p=0.076). Conclusion: The majority of this sample of older adults were partially edentulous and of normal nutritional status. Those with 10-19 teeth were more likely to be at risk for malnutrition. Further studies are needed to examine relationships between tooth loss and malnutrition risk and the impact of impaired dentition on the eating experience in a larger sample and to inform clinical practice.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66884770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
COPING WITH ANXIETY, DEPRESSION, BURDEN AND QUALITY OF LIFE IN INFORMAL PRIMARY CAREGIVERS OF COMMUNITY-DWELLING INDIVIDUALS WITH DEMENTIA 应对社区居住的痴呆症患者的非正式初级照顾者的焦虑、抑郁、负担和生活质量
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.22
M. Muscat, C. Scerri
{"title":"COPING WITH ANXIETY, DEPRESSION, BURDEN AND QUALITY OF LIFE IN INFORMAL PRIMARY CAREGIVERS OF COMMUNITY-DWELLING INDIVIDUALS WITH DEMENTIA","authors":"M. Muscat, C. Scerri","doi":"10.14283/jarcp.2018.22","DOIUrl":"https://doi.org/10.14283/jarcp.2018.22","url":null,"abstract":"Objective: This study aimed to investigate how informal primary caregivers of individuals with dementia living in the community cope with caring-related measures of anxiety, depression, burden and quality of life. Participants and Design: Participants included 60 informal caregivers (23 males and 37 females) of community-dwelling individuals with dementia who attended a state-run geriatric day hospital in Malta. Caregiver measures included the Hospital Anxiety and Depression Scale, the World Health Organization Quality of Life–BREF and Brief COPE questionnaires, and Zarit Burden Interview. The Mini Mental State Examination and Barthel Index of Activities of Daily Living scores were used to determine the degree of cognitive impairment and performance in activities of daily living of care-recipients. Results: Informal caregivers experienced anxiety and depression with both emotional distress states negatively affecting all quality of life domains. Depression and burden experienced by informal primary caregivers showed a strong association with individuals with dementia-related variables such as age, cognitive impairment and activities of daily living scores. The use of dysfunctional coping strategies was found to be related to caregivers’ emotional distress, low quality of life and burden. Conclusion: The findings indicate that informal primary caregivers experienced anxiety and depression, had a lower quality of life, and feel burdened during their caring role. However, caregivers making use of emotion-focused coping strategies were found to be protected against emotional distress. The results highlight the need of providing support services aimed at promoting the psychological wellbeing of informal carers of community-dwelling individuals with dementia.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66885004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
SHORT TERM (24 HOURS) AND LONG TERM (1 YEAR) ASSESSMENTS OF RELIABILITY IN OLDER ADULTS: CAN ONE REPLACE THE OTHER? 老年人的短期(24小时)和长期(1年)可靠性评估:两者可以相互替代吗?
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.15
T. Abe, S. Dankel, S. Buckner, M. Jessee, K. Mattocks, J. Mouser, Z. Bell, J. Loenneke
{"title":"SHORT TERM (24 HOURS) AND LONG TERM (1 YEAR) ASSESSMENTS OF RELIABILITY IN OLDER ADULTS: CAN ONE REPLACE THE OTHER?","authors":"T. Abe, S. Dankel, S. Buckner, M. Jessee, K. Mattocks, J. Mouser, Z. Bell, J. Loenneke","doi":"10.14283/jarcp.2018.15","DOIUrl":"https://doi.org/10.14283/jarcp.2018.15","url":null,"abstract":"There may be some individuals who do not adapt favorably to an exercise stimulus. This is most commonly determined by assessing the error of the measurement across two separate testing sessions separated by a short period of time. It has been recommended that this error be assessed over the same time frame as the intervention. We examined the 24-h test-retest reliability (n=18, aged 42 to 64 years) of forearm muscle thickness, handgrip strength, and “muscle quality” and compared that to the reliability observed when visits are separated by 1-year (n=80, aged 60 to 79 years). The measurement errors were greater in all measured variables following test-retest separated by 1-year than the test-retest separated by 24-hours. Our findings suggest that a time-matched control group is likely important to fully capture the error of the tester as well as the error associated with random biological variability within a timed intervention.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66884984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
THE NOVEL FRAILTY INDEX (NFI) CORRELATES WITH A VALUE OF PHASE ANGLE AND MNA IN HOSPITALISED AND FREELIVING ELDERLY - PRELIMINARY REPORT 新的衰弱指数(nfi)与相位角值和mna在住院和自由生活老年人中的相关性——初步报告
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.21
E. Wernio, J. A. D. ska, Hanna Kujawska-Danecka, A. Hajduk, Z. Zdrojewski, S. M. gorzewicz
{"title":"THE NOVEL FRAILTY INDEX (NFI) CORRELATES WITH A VALUE OF PHASE ANGLE AND MNA IN HOSPITALISED AND FREELIVING ELDERLY - PRELIMINARY REPORT","authors":"E. Wernio, J. A. D. ska, Hanna Kujawska-Danecka, A. Hajduk, Z. Zdrojewski, S. M. gorzewicz","doi":"10.14283/jarcp.2018.21","DOIUrl":"https://doi.org/10.14283/jarcp.2018.21","url":null,"abstract":"Introduction: To improve the quality of life and health of the elderly, attention is paid to the early detection of frailty syndrome. Unfortunately, one simple and practical screening tool has not been established yet. Recently came the proposal of the Novel Frailty Index (NFI) created by Yamada and Arai. Therefore, the purpose of this study was to assess the relationship between nutritional status and NFI of the elderly. Materials and methods: In a group of 67 elderly patients (27 hospitalised and 40 living in the home environment) we used the NFI and evaluated nutritional status with the use of full-MNA together with SNAQ (appetite questionnaire), manual dynamometry and bioimpedance analysis. Results: Based on the NFI results, frailty syndrome was diagnosed in more than half of hospitalised elderly. The syndrome was significantly less prevalent in free-living older people (15% vs 63%, p<0.001).We found the significant correlations of NFI values with age (r=0.031, p=0.03), co-morbidity(r=0.295, p=0.016), phase angle (r=-0.407, p<0.001), full-MNA score (r=-0.515, p<0.001). Conclusions: Our preliminary results suggest the relevant association between NFI results and age, phase angle as well comorbidity and nutritional status. So further evaluation of NFI as a screening tool for frailty syndrome diagnose is needed.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66885424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SENILE ANOREXIA AND HYPERALDOSTERONISM 老年厌食症和高醛固酮增多症
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.6
D. Schwerthöffer, T. Grimmer, I. Bauer
{"title":"SENILE ANOREXIA AND HYPERALDOSTERONISM","authors":"D. Schwerthöffer, T. Grimmer, I. Bauer","doi":"10.14283/jarcp.2018.6","DOIUrl":"https://doi.org/10.14283/jarcp.2018.6","url":null,"abstract":"Objective and Method: A case presentation of a 73-year-old delirious patient diagnosed with hyperaldosteronism and Anorexia Nervosa. A possible pathophysiological relationship between a decades-long uncontrolled eating disorder (so called Senile Anorexia) and a resulting transformation of the adrenal gland is discussed. Results and Conclusion: Senile anorexia can remain undetected for decades only to then manifest itself through somatic complications, e.g. symptoms of hyperaldosteronism. In older, underweight patients with unclear neuropsychiatric symptoms, the diagnosis of Anorexia Nervosa should be considered.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66885442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INADEQUACY OF N-3 POLYUNSATURATED FATTY ACID DIETARY INTAKES IN THE GENERAL FRENCH POPULATION OF ELDERLY (65 TO 79 YEARS OLD): THE INCA 2 SURVEY 法国一般老年人(65至79岁)饮食中n-3多不饱和脂肪酸摄入不足:印加2调查
JAR life Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.13
Benjamin Buaud, J. Tressou, P. Guesnet, Noémie Simon, S. Pasteau
{"title":"INADEQUACY OF N-3 POLYUNSATURATED FATTY ACID DIETARY INTAKES IN THE GENERAL FRENCH POPULATION OF ELDERLY (65 TO 79 YEARS OLD): THE INCA 2 SURVEY","authors":"Benjamin Buaud, J. Tressou, P. Guesnet, Noémie Simon, S. Pasteau","doi":"10.14283/jarcp.2018.13","DOIUrl":"https://doi.org/10.14283/jarcp.2018.13","url":null,"abstract":"Objectives: The aim of this study was to explore polyunsaturated fatty acid (PUFA) intakes in the French elderly population (65 to 79 years old). Design: The study used data on French food consumption issued from 348 elderly of the cross-sectional national French INCA 2 dietary survey performed in 2006 and 2007, combined with the nutritional content of food consumed updated in 2013 by the French Information Center on Food Quality. Results: It was observed for the French elderly population an adequate total fat daily intake and a linoleic acid (LA) daily intake close or superior to the recommended dietary intake (RDI) by the French authorities (from 4.1 to 4.4% of the total energy intake excluding alcohol (EIEA) vs 4% EIEA). By contrast, the French elderly have, regardless of age and gender, a low mean dietary alpha-linolenic acid (ALA) intake equal half of the RDI (0.5% EIEA vs 1% EIEA), and a mean dietary docosahexaenoic acid (DHA) intake close to two-thirds of the RDI (i.e. from 154 to 167 mg/d vs 250 mg/d). These translated into a LA/ALA ratio between 9.5 and 9.9, twice as high as the recommended threshold inferior to 5, and a mean dietary eicosapentaenoic acid (EPA) plus DHA intake (from 267 to 293 mg/d) slightly more than half of the RDI (500 mg/d). Conclusion: This study supports the need to promote higher intakes of n-3 PUFAs, as well as the setting of specific intake recommendations for these fatty acids for the French elderly population.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66884875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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