Japanese journal of gastroenterology and hepatology最新文献

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Anti-Ribosomal P (Anti-P) Antibodies in Autoimmune Hepatitis Patients 自身免疫性肝炎患者的抗核糖体P抗体
Japanese journal of gastroenterology and hepatology Pub Date : 2021-01-01 DOI: 10.47829/jjgh.2021.61402
C. Gallo, A. Dellavance, R. Gama, Silva Ae, Silva Ise, Andrade Le, Ferraz Ml
{"title":"Anti-Ribosomal P (Anti-P) Antibodies in Autoimmune Hepatitis Patients","authors":"C. Gallo, A. Dellavance, R. Gama, Silva Ae, Silva Ise, Andrade Le, Ferraz Ml","doi":"10.47829/jjgh.2021.61402","DOIUrl":"https://doi.org/10.47829/jjgh.2021.61402","url":null,"abstract":"*Corresponding author: Clarisse Gallo, Division of Gastroenterology, Federal University of Sao Paulo, Sao Paulo, Brazil, E-mail: marialucia.ferraz@uol.com.br Received: 01 May 2021 Accepted: 22 May 2021 Published: 27 May 2021 Copyright: ©2021 Gallo C, This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and build upon your work non-commercially.","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal Ischemia Following Cardiac Surgery: An Unusual Clinical Presentation 心脏手术后肠缺血:一种不寻常的临床表现
Japanese journal of gastroenterology and hepatology Pub Date : 2021-01-01 DOI: 10.47829/jjgh.2021.7902
Atmani N, Seghrouchni A, Mounir R, M. S, E. Y, M. Y
{"title":"Intestinal Ischemia Following Cardiac Surgery: An Unusual Clinical Presentation","authors":"Atmani N, Seghrouchni A, Mounir R, M. S, E. Y, M. Y","doi":"10.47829/jjgh.2021.7902","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7902","url":null,"abstract":"1. Abstract Mesenteric ischemia is a dreadful complication with a high mortality rate. Early diagnosis and management is mandatory to improve prognosis. We report a 72-year-old woman who has undergone a bioprosthetic aortic valve replacement. She presented an abdominal pain associated to an occlusive syndrome. Angio-CT scan has found initially a functional bowel obstruction without mesenteric ischemia. 3 days later, she became febrile and her abdominal distension increase. The fellow up Angio-CT scan revealed a pneumoperitoneum suggestive of a bowel perforation. A diagnostic laparotomy had found two ischemic ileal perforations. The ischemic origin was confirmed by histo-pathological examination. She underwent segmental ileal resection with end-to-end anastomosis. The follow up was favourable. 2. Introduction Gastrointestinal complications after cardiac surgery are rare, but are associated with significant morbidity and mortality witch varies between 13,9 and 63% [1-3]. Mesenteric ischemia accounts for approximately 14% of post cardiac surgery gastrointestinal complications with a mortality rate of 50-100% in some studies [3]. Early diagnosis allows timely management to improve patient prognosis. However, definitive diagnosis remains difficult in most cases because of the variety and non-specificity of clinical presentations. We presented a case of a non-specific clinical presentation of a postischemic bowel perforation, revealed by an occlusive syndrome after biological aortic valve replacement. She was successfully undergone a surgical resection of the ischemic bowel. 3. Observation A 72-year-old woman was admitted to our department for a severe symptomatic aortic valve stenosis. Her medical history included diabetes mellitus, hypertension, osteoporosis and a primary thrombocytopenia. The left ventricular ejection fraction was normal (63%) and coronarography revealed atherosclerosis without significant stenosis. She underwent a bioprosthetic aortic valve replacement. The cardiopulmonary bypass (CPB) and cardiac ischemic times were 84 and 55 minutes, respectively. She was extubated 4 hours after surgery and unfractionated heparin was started at 6th hours, replaced by a low molecular weight heparin after drains removal. At postoperaive day (POD) 5, she presented a diffuse abdominal pain associated with an abdominal distension. The clinical examination was unremarkable. Laboratory parameters revealed elevated white blood cell (WBC) count (16,000/μl) and C-reactive protein (CRP) level (27 mg/dl), but a normal lactate rate (1.2 mmol/L). Abdominal angio-CT scan was performed, it showed a functional bowel obstruction with a normal mesenteric vascularization (Figure 1). The general surgery recommended a simple observation. Three days after (at POD 8) she presented fever (38°C) and an increase of abdominal distension with persistent of abdominal pain. At the examination right lower quadrant tenderness developed. Laboratory exams revealed persistent of a ","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive factors of bowel resection due to an incarcerated groin hernia 嵌顿性腹股沟疝肠切除术的预测因素
Japanese journal of gastroenterology and hepatology Pub Date : 2020-06-18 DOI: 10.21203/rs.3.rs-23453/v1
T. Udaka, A. Taniguchi, Jun Kozai, T. Ootsuka, N. Watanabe, I. Endou, O. Yoshida, Hiroaki Asano, M. Kubo
{"title":"Predictive factors of bowel resection due to an incarcerated groin hernia","authors":"T. Udaka, A. Taniguchi, Jun Kozai, T. Ootsuka, N. Watanabe, I. Endou, O. Yoshida, Hiroaki Asano, M. Kubo","doi":"10.21203/rs.3.rs-23453/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-23453/v1","url":null,"abstract":"\u0000 Purpose\u0000\u0000In this retrospective study, we assessed factors that can be used to predict the need for bowel resection due to an incarcerated groin hernia.\u0000Methods\u0000\u0000We enrolled a total of 83 patients diagnosed with an incarcerated groin hernia on preoperative unenhanced computed tomography (CT) between January 2010 and December 2019 in our hospital. They were divided into two groups: those who underwent bowel resection and those who did not. The clinical findings, blood test results, and unenhanced CT values of patients were examined and compared between the two groups. The indication of intestinal resection was macroscopic necrosis or perforation of the incarcerated intestine.\u0000Results\u0000\u0000A total of 83 patients with incarcerated groin hernias were included in our study, of whom 13 (15.7%) had undergone bowel resection surgery. A univariate analysis identified a prolonged time from the symptom onset to surgery, increased white blood cell (WBC) count, increased C-reactive protein (CRP) level, decreased albumin level, and CT attenuation of the incarcerated intestinal wall at the fundus as significant predictive factors. The cut-off value for prediction of intestinal resection was 25 HU for the average CT attenuation of the incarcerated intestinal wall at the fundus and a WBC of 11,550 based on the receiver operating characteristic (ROC) curve. A multivariate analysis showed CT attenuation of the incarcerated intestinal wall at the fundus and an increased WBC count to be independent predictive factors.\u0000Conclusions\u0000\u0000Measuring unenhanced CT attenuation of the incarcerated intestinal wall at the fundus and the WBC count was suggested to be necessary for determining whether or not resection of the incarcerated intestine is required in cases of groin hernia.","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67958760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synchronous Colitis Induced by Hot Water Enema-An Easily Missed Etiology for Colitis in Modern Days 热水灌肠致同步性结肠炎——现代结肠炎的一个容易被忽视的病因
Japanese journal of gastroenterology and hepatology Pub Date : 2020-01-01 DOI: 10.47829/JJGH.2020.5703
Hsu Tc, Sun Wc, Chen Mj, Lin Wc, Wang Hy
{"title":"Synchronous Colitis Induced by Hot Water Enema-An Easily Missed Etiology for Colitis in Modern Days","authors":"Hsu Tc, Sun Wc, Chen Mj, Lin Wc, Wang Hy","doi":"10.47829/JJGH.2020.5703","DOIUrl":"https://doi.org/10.47829/JJGH.2020.5703","url":null,"abstract":"Synchronous Colitis Induced by Hot Water Enema-An Easily Missed Etiology for Colitis in Modern Days Hsu TC1,2,3*, Sun WC1, Chen MJ3, Lin WC4 and Wang HY4 1Division of Colon and Rectal Surgery, Department of Surgery, Taipei Mackay Memorial Hospital, Taipei, Taiwan 2Department of Surgery, Taipei Medical University, Taipei, Taiwan 3Department of Surgery, Mackay Medical College, New Taipei, Taiwan 4Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The MYTHS of De novo Crohn's Disease After Restorative Proctocolectomy with Ileal Pouch-anal Anastomosis for Ulcerative Colitis. 溃疡性结肠炎恢复性直结肠切除术回肠袋肛管吻合术后新发克罗恩病的误区。
S D James, A T Hawkins, J W Um, B R Ballard, D T Smoot, A E M'Koma
{"title":"The MYTHS of <i>De novo</i> Crohn's Disease After Restorative Proctocolectomy with Ileal Pouch-anal Anastomosis for Ulcerative Colitis.","authors":"S D James,&nbsp;A T Hawkins,&nbsp;J W Um,&nbsp;B R Ballard,&nbsp;D T Smoot,&nbsp;A E M'Koma","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>1.1.Inflammatory Bowel Disease (IBD) are the manifestation of overzealous dys-regulated immune response in the intestinal tract, directed primarily against the indigenous microbes combined with defective functioning of anti-inflammatory pathways. Finding a trustable lead to predicting <i>de novo</i> Crohn's Disease (CD) prior to performing \"pouch surgery\", Restorative Proctocolectomy (RPC) with Ileal Pouch-Anal Anastomosis (IPAA) for UC and/or Indeterminate Colitis (IC) is clinically important and remains debatable. <i>De novo</i> CD is a subsequent long-term postoperative complication in IBD patients with Ulcerative Colitis (UC) undergoing IPAA. Herewith we discuss this understanding in laboratory-based basic science research, with its molecular application as a possible corner stone tool for clinical progress and success in the IBD Clinic. Crypt Paneth cell (PCs) secreted enteroendocrine alpha-defensin 5 (<i>DEFA5</i>)\" if developed properly is likely to solve diagnostic and prognostic difficulty in IBD Clinics. <i>DEFA5</i> has shown the ability to differentiate the predominant subtypes of colonic IBD (CC <i>vs</i>. UC) at first endoscopy biopsy, avoiding diagnosis delay prior to colectomy. In addition, <i>DEFA5</i> accurately circumvents indeterminate colitis (IC) patients into accurate IBD subtype (UC or CC). Further, <i>DEFA5</i> can be used in selecting CC patients that may have positive outcomes after IPAA surgery [1]. Furthermore, likewise, <i>DEFA5</i> can predict UC patients likely to have positive or poor outcome, e.g. those patients that are likely to transform/ convert and adhere to <i>de novo</i> Crohn's after IPAA can be picked up in endoscopy biopsy before surgery.</p><p><strong>Aim: </strong>1.2.To assessed comprehensive state-of-the-art understanding domains on the <i>de novo</i> Crohn's disease subsequent to IPAA surgery for ulcerative colitis.</p><p><strong>Methods: </strong>1.3.A literature search based on preferred reporting items for over-review and meta-analysis protocols (PRISMA-P) was performed. A comprehensive current search of PubMed, MEDLINE, CINAHL, Embase, Google<sup>®</sup> search engine and Cochrane Database of collected reviews was performed from January 1990 through December 2018. The search consists of retrospective studies and case reports of reporting postoperative <i>de novo</i> CD incidence and adverse events. Secondary and hand/manual searches of reference lists, other studies cross-indexed by authors, reviews, commentaries, books and meeting abstracts were also performed. Studies were included only if the diagnosis of <i>de novo</i> CD was established clinically and histologically based on inflammation of afferent limb(s) or perianal disease. The search excluded non-English language and non-human studies as well as editorials.</p><p><strong>Results: </strong>1.4.Published data on <i>de novo</i> CD developing after RPC with IPAA are still limited. A total of three hundred a","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10075805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pneumobilia 胆道积气
Japanese journal of gastroenterology and hepatology Pub Date : 2020-01-01 DOI: 10.47829/jjgh.2020.5701
Fekaj E
{"title":"Pneumobilia","authors":"Fekaj E","doi":"10.47829/jjgh.2020.5701","DOIUrl":"https://doi.org/10.47829/jjgh.2020.5701","url":null,"abstract":"","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colon Versus Rectal Cancers among Surgical Approach: An Observational Study 结肠和直肠癌手术入路:一项观察性研究
Japanese journal of gastroenterology and hepatology Pub Date : 2020-01-01 DOI: 10.47829/jjgh.2020.5604
Mohamed Wm, Al-Ani Uft, Hathcock Ma, Alshewered As
{"title":"Colon Versus Rectal Cancers among Surgical Approach: An Observational Study","authors":"Mohamed Wm, Al-Ani Uft, Hathcock Ma, Alshewered As","doi":"10.47829/jjgh.2020.5604","DOIUrl":"https://doi.org/10.47829/jjgh.2020.5604","url":null,"abstract":"1. Abstract 1.1. Background: Colorectal cancer is the most common tumor of the gastrointestinal tract, and it is the third leading cause of mortality throughout the world. 1.2. Objectives: An observational study of colorectal cancers. 1.3. Methods: The research was carried out in Abu Ghraib General hospital in the period from January 2019 to May 2019. The primary data reported included colorectal cancer, and patients study characterizes. These including gender, age, family history, smoking, comorbidity, IBD, tumor sites, histopathology, stages, grading, the distance for anal verge, local recurrence, distant metastasis, type of surgery, and chemoradiation. 1.4. Results: The gender was composed of male 40%, and female 60%, with mean age, was 44.89±21.6 years for males and 47.55±20.07 years for females. There was only 4% had a positive family history. Smoking patients in this study were 48%, yet the non-smoker patients were 52%. Rectosigmoid cancer represented the most common site of cancer figured in 40% of patients. The results showed that adenocarcinoma was the most common histopathology in 72% of patients. The localized tumors were recorded in 44%, whereas metastasis was found in 34% of patients. Regarding grading, the moderate differentiation was the dominant grade in 60%. The tumor distant from anal verge results exhibited as <5 cm in 7(14%), 5-10 cm in 30(60%), and >10 cm in 13(26%). The majority of patients in our study have no metastatic disease 66%. Indeed, the hepatic was the most frequent site of distant metastasis. All patients underwent different surgical procedures. 1.5. Conclusions: Middle age group was mostly effect and more in the female gender. Many factors are shown to increase the risk of developing colorectal cancer including increasing age; consumption of processed meat, and smoking. Rectosigmoid cancer represented the most current sites. The localized diseases were common. Moderate differentiation was the dominant grade. The tumor location and the distal tumor margin are essential factors upon which the surgical plan for patients with rectal cancer is based. Accurate measurement of the distal tumor margin is necessary for planning the surgical procedure. The liver was the most frequent site of distant metastasis that figured. 2. Introduction The highest colon cancer incidence rates are found in parts of Europe (eg, in Hungary, Slovenia, Slovakia, the Netherlands, and Norway), Australia/New Zealand, Northern America, and Eastern Asia (Japan and the Republic of Korea, Singapore [in females]), with Hungary and Norway ranking first among males and females, respectively [1]. The incidences are elevated in Uruguay among both men and women. Rectal cancer incidence rates have a similar regional distribution, although the highest rates are seen in the Republic of Korea among males and Macedonia among females [1]. Rates of both colon and rectal cancer incidence tend to be low in most regions","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory Bowel Disease On-Line Web-Based Guide to Health Professionals and Patients in Developing and African Nations. 发展中国家和非洲国家卫生专业人员和患者炎症性肠病在线网络指南》。
Japanese journal of gastroenterology and hepatology Pub Date : 2020-01-01 Epub Date: 2020-03-11
A M Herman, A T Hawkins, S D James, B R Ballard, A E M'Koma
{"title":"Inflammatory Bowel Disease On-Line Web-Based Guide to Health Professionals and Patients in Developing and African Nations.","authors":"A M Herman, A T Hawkins, S D James, B R Ballard, A E M'Koma","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>1.1.Inflammatory Bowel Disease (IBD) is recklessly evolving worldwide as incautious disaster, especially in developing nations as a regional duplicitous emergence disease. It has come to light that adaptive Western culture, rapid urbanization lifestyle in the developing nations has been seen to be associated with this increasing trend incidence. Apparent unclassified strategic challenge assessment of how key trends and uncertainties might lead the world over the next decades to help developing nations and plan for the long term. Healthcare professionals are faced with limited resource and unequipped laboratories for IBD diagnostics, prognostics and monitoring management. Limited knowledge on IBD among developing nation's physician's/healthcare providers is painstaking and indisputable challenge. With the emergence of advanced communications technology, the internet offers diverse, substantial, easily accessible, and educational resources that are more time- and cost-efficient than conventional modes of knowledge acquisition. An On-Line Web-Based Resources about IBD, as a guide would greatly assist health professionals and patients.</p><p><strong>Methods: </strong>1.2.We performed a literature search according to PRISMA-P (preferred reporting items for review and meta-analysis and searches in PubMed (MEDLINE database) to identify and select peer-reviewed articles allied to web-based educational accoutrements for IBD.</p><p><strong>Results: </strong>1.3.In developing nations, locally trained physicians have limited knowledge on IBD. Mostly, IBD is not included in their training Core Curriculum and research in this field/area is limited in these countries. The healthcare approaches, both at the primary care and referral levels, many times lack the essential regular clinical guidance and laboratory evaluation assessments needs for monitoring patients. Moreover, increasing treatment costs impose additional burden on the healthcare systems. Expensive pharmacological biosimilar and biologic agents/drugs, new treatment targets, and new quality indicators in patient health quality of life and care are significant challenge in addition to early manifestations of IBD are likely to be missed at most health institutions.</p><p><strong>Conclusion: </strong>1.4.We herewith summarize an on-line web-based e-learning guide for IBD-related educational resources to assist physicians, healthcare personnel and patients worldwide, especially in the developing nations where the epidemiological monitoring studies are limited, due to a lack of medical surveillance systems and reliable and unified registries and databases.</p>","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10104455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oropharyngeal Transition during Swallowing between Stroke and Head and Neck Cancer Survivors 脑卒中和头颈癌幸存者吞咽时口咽过渡
Japanese journal of gastroenterology and hepatology Pub Date : 2020-01-01 DOI: 10.47829/jjgh.2020.5405
C. Deckelman, Y. Kim, T. Park
{"title":"Oropharyngeal Transition during Swallowing between Stroke and Head and Neck Cancer Survivors","authors":"C. Deckelman, Y. Kim, T. Park","doi":"10.47829/jjgh.2020.5405","DOIUrl":"https://doi.org/10.47829/jjgh.2020.5405","url":null,"abstract":"1. Abstract 1.1. Objective: The purpose of this study was to analyze three oropharyngeal bolus transition timings, Oral Transition Time (OTT), Pharyngeal Transition Time (PTT), and Duration of Upper Esophageal Sphincter Opening (DUESO), using videofluoroscopic swal lowing examinations (VFSEs) between stroke survivors and head and neck cancer survivors to determine differences between the two populations. 1.2. Methods: Means and standard deviations of OTT, PTT, and DUESO were determined from analyzing two 5ml thin liquid swallows exhibited by each of the 15 stroke survivors and 15 head and neck cancer survivors from the VFSEs. Statistical analyses were made using one-way analysis of variance (ANOVA) using the two groups with the statistical level set at p < .05.","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70925928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Concurrent Gastric Hyperplastic and Fundic Gland Polyps in a Patient Taking Proton-Pump Inhibitor 服用质子泵抑制剂的患者并发胃增生和基底腺息肉
Japanese journal of gastroenterology and hepatology Pub Date : 2020-01-01 DOI: 10.47829/jjgh.2020.5603
N. Nishimura, M. Mizuno
{"title":"Concurrent Gastric Hyperplastic and Fundic Gland Polyps in a Patient Taking Proton-Pump Inhibitor","authors":"N. Nishimura, M. Mizuno","doi":"10.47829/jjgh.2020.5603","DOIUrl":"https://doi.org/10.47829/jjgh.2020.5603","url":null,"abstract":"1. Clinical Image A 61-year-old man presented with iron-deficiency anemia (hemoglobin, 8.1 g/dl). He had been taking warfarin and low-dose aspirin for atrial fibrillation and post mitral valve replacement. He had also taken 15 mg lansoprazole daily for 6 years for treatment of gastroesophageal reflux disease. Serum anti-Helicobacter pylori IgG antibody and H. pylori testing of gastric biopsies were negative. Esophagogastroduodenoscopy revealed more than 20 pale pink, pedunculated polyps of up to 20-mm diameter (Figure 1) and fewer light-red polyps in the gastric body and fundus. The fundic mucosa appeared non-atrophic. The largest of the pale pink polyps and one large, red polyp (Figure 2) were resected endoscopically. Histological examination of the pale pink polyp revealed fundic gland mucosa with cystic, dilated glands, consistent with fundic gland polyp. Histological examination of the large, red polyp revealed elongation and branching of foveolae, characteristic of a hyperplastic polyp, without atypia, (Figure 3). Lansoprazole was discontinued because of suspected association between its use and gastric polyps. Follow-up endoscopy 5 months later revealed fewer and smaller gastric polyps (Figure 4). The anemia had resolved with iron treatment and did not recur. Gastric fundic grand polyps develop with long-term use of proton-pump inhibitors [1]. Hyperplastic polyps usually occur in patients with H. pylori infection [2], but association between use of the medication and hyperplastic polyps is unclear. This case demonstrates that long-term PPI therapy induces the development of gastric hyperplastic polyps and fundic gland polyps in patients without H. pylori infection. Figure 1: Esophagogastroduodenoscopy revealed more than 20 pale pink, pedunculated polyps of up to 20-mm diameter in the gastric body.","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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