Nkhaili A, S. R., A. M., C. F, Errami Aa, O. S, S. Z, K. K
{"title":"Primary Biliary Cholangitis and Type 1 Diabetes in A Male Patient: A Case Report","authors":"Nkhaili A, S. R., A. M., C. F, Errami Aa, O. S, S. Z, K. K","doi":"10.47829/jjgh.2021.8102","DOIUrl":"https://doi.org/10.47829/jjgh.2021.8102","url":null,"abstract":"Primary Biliary Cholangitis (PBC) isa cholestatic disease of autoimmune origin characterized by the destruction of small to medium size intrahepatic bile ducts due to lymphocytic infiltration. The diagnosis is made by the presence of Anti-Mitochondrial Antibodies (AMAs) specific for the disease. PBC typically affects middle-aged women and is often associated with other autoimmune pathologies which are in decreasing order of frequency: Sjogren's syndrome, autoimmune dysthyroidism, scleroderma, rheumatoid arthritis, lupus and celiac diseasewhich are also more common in women. Few clinical studies evaluate the presentation of PBC in men with concomitant type 1 diabetes due to its low incidence compared to the prevalence of PBC in women.This case report presents that of a male patient with type 1 diabetes, admitted for cholestatic jaundice with pruritus, and in whom the diagnosis of PBC was only made late in the cirrhosis stage","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Padilla-Machaca Pm, G. L., Cardenas B, C. C., E. S., Mantilla O, Rivera J, Solar A, M. A., Bacilio W, Rondon C
{"title":"Prevalence and Risk Factors of Chronic Kidney Disease After Liver Transplantation: Outcomes in The Main Transplant Center of Peru","authors":"Padilla-Machaca Pm, G. L., Cardenas B, C. C., E. S., Mantilla O, Rivera J, Solar A, M. A., Bacilio W, Rondon C","doi":"10.47829/jjgh.2021.7103","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7103","url":null,"abstract":"Prevalence and Risk Factors of Chronic Kidney Disease After Liver Transplantation: Outcomes in The Main Transplant Center of Peru Padilla-Machaca PM1,2*, Gonzales-Hamada L1, Cardenas B1, Cerron C1, Espinoza-Rivera S1, Mantilla O1, Rivera J1, Solar A1, Montufar A1, Bacilio W1 and Rondon C1 1Transplant Department. Guillermo Almenara National Hospital. EsSalud. Lima. Peru 2Department of Medicine National University of San Marcos. Lima. Peru","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pros and Cons of Iron Deficiency and Iron Deficiency Anaemia","authors":"A. Ekladious","doi":"10.47829/jjgh.2021.7801","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7801","url":null,"abstract":"","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Sign of Chilaiditi","authors":"B. W., J. L, Laamrani Fz","doi":"10.47829/jjgh.2021.61903","DOIUrl":"https://doi.org/10.47829/jjgh.2021.61903","url":null,"abstract":"","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70926391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mass Spectrometry-Based Proteomics in Alcoholic and Non-Alcoholic Steatohepatitis","authors":"Hetland Le, Kimer N, G. L.","doi":"10.47829/jjgh.2021.7502","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7502","url":null,"abstract":"","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Massive Venous Air Embolism After Liver Transplantation","authors":"Marrone G, Caruso S, C. F","doi":"10.47829/jjgh.2021.7501","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7501","url":null,"abstract":"","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Future Considerations of Biological Disparities in Drug Development for NAFLD/ NASH: Trial Design and Analysis","authors":"S. A, M. W, Chow Sc","doi":"10.47829/jjgh.2021.7403","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7403","url":null,"abstract":"Ayako Suzuki MD, PhD, MSc, Gastroenterology, Department of Medicine, Duke University, 40 Duke Medicine Cir, Suite DUMC 3913, Durham, NC 27710, USA, E-mail: Ayako.Suzuki@duke.edu; Shein-Chung Chow, PhD, Biostatistics & Bioinformatics, Duke University, 2424 Erwin Road Ste 1102, 11037 Hock Plaza, Durham, NC 27705, Duke Box 2721, Durham, NC 27710, E-mail: sheinchung.chow@duke.edu Received: 05 Sep 2021 Accepted: 30 Sep 2021 Published: 06 Oct 2021 Copyright:","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atmani N, Seghrouchni A, Mounir R, M. S, E. Y, M. Y
{"title":"Intestinal Ischemia Following Cardiac Surgery: An Unusual Clinical Presentation","authors":"Atmani N, Seghrouchni A, Mounir R, M. S, E. Y, M. Y","doi":"10.47829/jjgh.2021.7902","DOIUrl":"https://doi.org/10.47829/jjgh.2021.7902","url":null,"abstract":"1. Abstract Mesenteric ischemia is a dreadful complication with a high mortality rate. Early diagnosis and management is mandatory to improve prognosis. We report a 72-year-old woman who has undergone a bioprosthetic aortic valve replacement. She presented an abdominal pain associated to an occlusive syndrome. Angio-CT scan has found initially a functional bowel obstruction without mesenteric ischemia. 3 days later, she became febrile and her abdominal distension increase. The fellow up Angio-CT scan revealed a pneumoperitoneum suggestive of a bowel perforation. A diagnostic laparotomy had found two ischemic ileal perforations. The ischemic origin was confirmed by histo-pathological examination. She underwent segmental ileal resection with end-to-end anastomosis. The follow up was favourable. 2. Introduction Gastrointestinal complications after cardiac surgery are rare, but are associated with significant morbidity and mortality witch varies between 13,9 and 63% [1-3]. Mesenteric ischemia accounts for approximately 14% of post cardiac surgery gastrointestinal complications with a mortality rate of 50-100% in some studies [3]. Early diagnosis allows timely management to improve patient prognosis. However, definitive diagnosis remains difficult in most cases because of the variety and non-specificity of clinical presentations. We presented a case of a non-specific clinical presentation of a postischemic bowel perforation, revealed by an occlusive syndrome after biological aortic valve replacement. She was successfully undergone a surgical resection of the ischemic bowel. 3. Observation A 72-year-old woman was admitted to our department for a severe symptomatic aortic valve stenosis. Her medical history included diabetes mellitus, hypertension, osteoporosis and a primary thrombocytopenia. The left ventricular ejection fraction was normal (63%) and coronarography revealed atherosclerosis without significant stenosis. She underwent a bioprosthetic aortic valve replacement. The cardiopulmonary bypass (CPB) and cardiac ischemic times were 84 and 55 minutes, respectively. She was extubated 4 hours after surgery and unfractionated heparin was started at 6th hours, replaced by a low molecular weight heparin after drains removal. At postoperaive day (POD) 5, she presented a diffuse abdominal pain associated with an abdominal distension. The clinical examination was unremarkable. Laboratory parameters revealed elevated white blood cell (WBC) count (16,000/μl) and C-reactive protein (CRP) level (27 mg/dl), but a normal lactate rate (1.2 mmol/L). Abdominal angio-CT scan was performed, it showed a functional bowel obstruction with a normal mesenteric vascularization (Figure 1). The general surgery recommended a simple observation. Three days after (at POD 8) she presented fever (38°C) and an increase of abdominal distension with persistent of abdominal pain. At the examination right lower quadrant tenderness developed. Laboratory exams revealed persistent of a ","PeriodicalId":73535,"journal":{"name":"Japanese journal of gastroenterology and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70927786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}