结肠和直肠癌手术入路:一项观察性研究

Mohamed Wm, Al-Ani Uft, Hathcock Ma, Alshewered As
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摘要

1. 抽象的1.1。背景:结直肠癌是最常见的胃肠道肿瘤,也是全球第三大死亡原因。1.2. 目的:对结直肠癌进行观察性研究。1.3. 方法:研究于2019年1月至2019年5月在阿布格莱布综合医院进行。报告的主要数据包括结直肠癌和患者的研究特征。这些因素包括性别、年龄、家族史、吸烟、合并症、IBD、肿瘤部位、组织病理学、分期、分级、肛门边缘距离、局部复发、远处转移、手术类型和放化疗。1.4. 结果:男性占40%,女性占60%,平均年龄:男性44.89±21.6岁,女性47.55±20.07岁。只有4%的人有阳性家族史。本研究中吸烟患者占48%,不吸烟患者占52%。直肠乙状结肠癌是最常见的癌症部位,占40%的患者。结果显示,72%的患者以腺癌为最常见的组织病理。44%的患者有局部肿瘤,而34%的患者有转移。分级方面,60%的分级以中度分化为主。13例(26%)肿瘤距离肛门边缘10 cm。我们研究中的大多数患者没有转移性疾病66%。事实上,肝脏是最常见的远处转移部位。所有患者都接受了不同的手术。1.5. 结论:以中年人群为主,以女性居多。许多因素都表明会增加患结直肠癌的风险,包括年龄增长;食用加工肉类和吸烟。直肠乙状结肠癌是最常见的部位。局部病变多见。中度分化为优势等级。肿瘤位置和肿瘤远端缘是直肠癌患者手术方案的重要依据。精确测量肿瘤远端边缘对于计划手术是必要的。肝脏是最常见的远处转移部位。2. 结肠癌发病率最高的地区是欧洲部分地区(如匈牙利、斯洛文尼亚、斯洛伐克、荷兰和挪威)、澳大利亚/新西兰、北美和东亚(日本和韩国、新加坡[女性]),其中匈牙利和挪威在男性和女性中分别排名第一,分别为100。在乌拉圭,男性和女性的发病率都有所上升。直肠癌发病率的区域分布相似,但最高的是大韩民国的男性和马其顿的女性。在大多数地区,结肠癌和直肠癌的发病率都很低
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Colon Versus Rectal Cancers among Surgical Approach: An Observational Study
1. Abstract 1.1. Background: Colorectal cancer is the most common tumor of the gastrointestinal tract, and it is the third leading cause of mortality throughout the world. 1.2. Objectives: An observational study of colorectal cancers. 1.3. Methods: The research was carried out in Abu Ghraib General hospital in the period from January 2019 to May 2019. The primary data reported included colorectal cancer, and patients study characterizes. These including gender, age, family history, smoking, comorbidity, IBD, tumor sites, histopathology, stages, grading, the distance for anal verge, local recurrence, distant metastasis, type of surgery, and chemoradiation. 1.4. Results: The gender was composed of male 40%, and female 60%, with mean age, was 44.89±21.6 years for males and 47.55±20.07 years for females. There was only 4% had a positive family history. Smoking patients in this study were 48%, yet the non-smoker patients were 52%. Rectosigmoid cancer represented the most common site of cancer figured in 40% of patients. The results showed that adenocarcinoma was the most common histopathology in 72% of patients. The localized tumors were recorded in 44%, whereas metastasis was found in 34% of patients. Regarding grading, the moderate differentiation was the dominant grade in 60%. The tumor distant from anal verge results exhibited as <5 cm in 7(14%), 5-10 cm in 30(60%), and >10 cm in 13(26%). The majority of patients in our study have no metastatic disease 66%. Indeed, the hepatic was the most frequent site of distant metastasis. All patients underwent different surgical procedures. 1.5. Conclusions: Middle age group was mostly effect and more in the female gender. Many factors are shown to increase the risk of developing colorectal cancer including increasing age; consumption of processed meat, and smoking. Rectosigmoid cancer represented the most current sites. The localized diseases were common. Moderate differentiation was the dominant grade. The tumor location and the distal tumor margin are essential factors upon which the surgical plan for patients with rectal cancer is based. Accurate measurement of the distal tumor margin is necessary for planning the surgical procedure. The liver was the most frequent site of distant metastasis that figured. 2. Introduction The highest colon cancer incidence rates are found in parts of Europe (eg, in Hungary, Slovenia, Slovakia, the Netherlands, and Norway), Australia/New Zealand, Northern America, and Eastern Asia (Japan and the Republic of Korea, Singapore [in females]), with Hungary and Norway ranking first among males and females, respectively [1]. The incidences are elevated in Uruguay among both men and women. Rectal cancer incidence rates have a similar regional distribution, although the highest rates are seen in the Republic of Korea among males and Macedonia among females [1]. Rates of both colon and rectal cancer incidence tend to be low in most regions
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