ISRN pediatrics最新文献_第7页

To Evaluate Serum Eosinophil Cationic Protein and Total IgE Concomitantly May Predict the Persistence of Wheezing in Young Children. 评估血清嗜酸性粒细胞阳离子蛋白和总IgE可预测幼儿喘息的持续性。

ISRN pediatrics Pub Date : 2012-01-01 Epub Date: 2012-12-24 DOI: 10.5402/2012/168379

Esengül Keleş, Hamza Yazgan, Arzu Gebeşçe

{"title":"To Evaluate Serum Eosinophil Cationic Protein and Total IgE Concomitantly May Predict the Persistence of Wheezing in Young Children.","authors":"Esengül Keleş, Hamza Yazgan, Arzu Gebeşçe","doi":"10.5402/2012/168379","DOIUrl":"https://doi.org/10.5402/2012/168379","url":null,"abstract":"Background. We investigated the predictive value and the relative risk of the evaluation of serum eosinophilic cationic protein (sECP) and total IgE levels concomitantly in relation to the persistence of wheezing in young children. Methods. The study was conducted prospectively between January 2007 and December 2010. A hundred and eight children, aged between three months and four years, with three or more episodes of wheezing, were studied to evaluate the role of eosinophil inflammation and its relation to persistence of wheezing two years later. Results. A statistically significant difference in terms of total IgE and sECP values was observed between the groups (P < 0.05). When measurement of IgE and sECP was assessed concomitantly, the sensitivity was found to be 92.68%, the negative predictive value was found to be 71.43%, accuracy rate was found to be 84.26%, and the relative risk was found to be 3.06 in group 1. Conclusions. In this study, we aimed to emphasize the importance of the assessment of sECP and total IgE concomitantly, as being two noninvasive and easily applicable tests, useful in predicting persistent wheezing in early childhood.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2012 ","pages":"168379"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/168379","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31162770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Assessment of exercise testing after repair of tetralogy of fallot. 法洛四联症修复后运动试验的评价。

ISRN pediatrics Pub Date : 2012-01-01 Epub Date: 2012-09-02 DOI: 10.5402/2012/324306

A A Kotby, H M Elnabawy, W M El-Guindy, R F Abd Elaziz

{"title":"Assessment of exercise testing after repair of tetralogy of fallot.","authors":"A A Kotby, H M Elnabawy, W M El-Guindy, R F Abd Elaziz","doi":"10.5402/2012/324306","DOIUrl":"https://doi.org/10.5402/2012/324306","url":null,"abstract":"Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease. The aim of this study was to examine the exercise performance of young patients following the repair of TOF and to assess the influence of different variables related to the surgical repair on exercise testing. This study was conducted on 21 patients (16 males and 5 females) operated on for TOF compared to 15 healthy age- and sex-matched control children. The patients' median age at time of the study was 8 years (range 5-13 years) while age at surgical repair was 5 ± 2.1 years (range 2-10 years). Patients were subjected to 2D and color Doppler echocardiographic examination. Treadmill exercise stress testing was performed for all subjects according to modified Bruce protocol. The resting ECGs of all patients revealed normal sinus rhythm and RBBB. Cases had lower exercise capacity when compared to control subjects and those with aortopulmonary shunt showed significantly lower exercise performance when compared to those without aortopulmonary shunt. In conclusions, exercise tolerance after total correction of TOF is slightly impaired on short-term followup with more affection among patients with previous aortopulmonary shunts. The present study did not reveal any serious ventricular arrhythmia.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2012 ","pages":"324306"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/324306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30902354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Strain echocardiography in early detection of Doxorubicin-induced left ventricular dysfunction in children with acute lymphoblastic leukemia. 应变超声心动图在早期发现急性淋巴细胞白血病患儿多柔比星诱发的左心室功能障碍中的应用。

ISRN pediatrics Pub Date : 2012-01-01 Epub Date: 2012-01-24 DOI: 10.5402/2012/870549

Mohammed Al-Biltagi, Osama Abd Rab Elrasoul Tolba, Mohammed Ramadan El-Shanshory, Nagla Abd El-Aziz El-Shitany, Eslam El-Sayed El-Hawary

{"title":"Strain echocardiography in early detection of Doxorubicin-induced left ventricular dysfunction in children with acute lymphoblastic leukemia.","authors":"Mohammed Al-Biltagi, Osama Abd Rab Elrasoul Tolba, Mohammed Ramadan El-Shanshory, Nagla Abd El-Aziz El-Shitany, Eslam El-Sayed El-Hawary","doi":"10.5402/2012/870549","DOIUrl":"10.5402/2012/870549","url":null,"abstract":"Objective. To investigate the ability of two-dimensional longitudinal strain echocardiography (2DST), to detect the early doxorubicin cardiotoxicity. Patients and Methods. The study included 25 children with newly diagnosed acute lymphoblastic leukemia (ALL) aged 5-15 years and 30 healthy control children. They had echocardiographic examination with conventional 2-dimensional (2D), pulsed tissue Doppler (PTD), and 2DST echocardiography before and within 1 week after doxorubicin treatment. Results. There was no significant difference in left ventricle (LV) systolic and diastolic functions measured by conventional 2-D and PTD echocardiography between patients and controls. However, there was significant decrease in LV global and peak systolic strain detected by 2-DST echocardiography in study group than control. After doxorubicin treatment, there was no significant difference in LV systolic and diastolic functions measured by conventional 2-D and PTD echocardiography than before treatment except for prolonged IVCT and IVRT, but LV global and peak systolic strain was significantly lower after treatment. Conclusion. 2-D longitudinal strain echocardiography was more sensitive than conventional 2-D and PTD in detecting the early LV doxorubicin-induced cardiotoxicity in children with ALL.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":" ","pages":"870549"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40170559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial bloodstream infections in neonates in a developing country. 发展中国家新生儿的细菌性血液感染。

ISRN pediatrics Pub Date : 2012-01-01 Epub Date: 2012-08-05 DOI: 10.5402/2012/508512

Daynia E Ballot, Trusha Nana, Charlotte Sriruttan, Peter A Cooper

{"title":"Bacterial bloodstream infections in neonates in a developing country.","authors":"Daynia E Ballot, Trusha Nana, Charlotte Sriruttan, Peter A Cooper","doi":"10.5402/2012/508512","DOIUrl":"https://doi.org/10.5402/2012/508512","url":null,"abstract":"Background. Ongoing surveillance of antimicrobial sensitivity patterns of bacteria isolated in bloodstream infections guides empiric antibiotic therapy in neonatal sepsis. Methods. Sensitivity profiles of neonatal bacterial bloodstream infections in a tertiary hospital were reviewed between 01/06/2009 and 30/06/2010 . Results. There were 246 episodes of bloodstream infection in 181 individuals-(14.06 episodes in10.35 patients/1000 patient days or 14.4 episodes in 10.6 babies/1000 live births. The majority were (93.5%) were late onset and most (54.9%) were gram positive. There were 2.28 sepsis-related deaths /1000 patient days or 2.3/1000 live births. Death was significantly associated with gram-negative infections (P < 0.001), multiple gestation (P < 0.001), shock (P = 0.008), NEC (P = 0.002), and shorter duration of hospital stay (P < 0.001). Coagulase-negative staphylococcus was isolated in 19.1%, K. pneumoniae ESBL in 12.1%, and A. baumanni in 10.9%. S. agalactiae predominated in early onset sepsis. Methicillin resistance was present in 86% of CoNS and 69.5% of S. aureus; 46% enterococcal isolates were ampicillin resistant. The majority (65%) of K. pneumoniae isolates were ESBL producers. Ampicillin resistance was present in 96% of E. coli. Conclusions. Penicillin and an aminoglycoside would be suitable empiric therapy for early onset sepsis and meropenem with gentamycin or ceftazidime with amikacin for late onset sepsis.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2012 ","pages":"508512"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/508512","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30856180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 109

Contemporary surgical management of severe sialorrhea in children. 当代儿童严重唾液病的外科治疗。

ISRN pediatrics Pub Date : 2012-01-01 Epub Date: 2012-03-28 DOI: 10.5402/2012/364875

Jeremy Hornibrook, Neil Cochrane

引用次数: 18

Frontal Plane Motion of the Pelvis and Hip during Gait Stance Discriminates Children with Diplegia Levels I and II of the GMFCS. 步态时骨盆和髋部的额面运动可区分 GMFCS I 级和 II 级偏瘫儿童。

ISRN pediatrics Pub Date : 2012-01-01 Epub Date: 2012-06-25 DOI: 10.5402/2012/163039

Renata Noce Kirkwood, Rosa de Lourdes Lima Dias Franco, Sheyla Cavalcanti Furtado, Ana Maria Forti Barela, Kevin John Deluzio, Marisa Cotta Mancini

{"title":"Frontal Plane Motion of the Pelvis and Hip during Gait Stance Discriminates Children with Diplegia Levels I and II of the GMFCS.","authors":"Renata Noce Kirkwood, Rosa de Lourdes Lima Dias Franco, Sheyla Cavalcanti Furtado, Ana Maria Forti Barela, Kevin John Deluzio, Marisa Cotta Mancini","doi":"10.5402/2012/163039","DOIUrl":"10.5402/2012/163039","url":null,"abstract":"Objective. To determine if gait waveform could discriminate children with diplegic cerebral palsy of the GMFCS levels I and II. Patients. Twenty-two children with diplegia, 11 classified as level I and 11 as level II of the GMFCS, aged 7 to 12 years. Methods. Gait kinematics included angular displacement of the pelvis and lower limb joints during the stance phase. Principal components (PCs) analyses followed by discriminant analysis were conducted. Results. PC1s of the pelvis and hip in the frontal plane differ significantly between groups and captured 80.5% and 86.1% of the variance, respectively. PC1s captured the magnitude of the pelvic obliquity and hip adduction angle during the stance phase. Children GMFCS level II walked with reduced pelvic obliquity and hip adduction angles, and these variables could discriminate the groups with a cross-validation of 95.5%. Conclusion. Reduced pelvic obliquity and hip adduction were observed between children GMFCS level II compared to level I. These results could help the classification process of mild-to-moderate children with diplegia. In addition, it highlights the importance of rehabilitation programs designed to improve pelvic and hip mobility in the frontal plane of diplegic cerebral palsy children level II of the GMFCS.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2012 ","pages":"163039"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30760035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An exploratory investigation of some statistical summaries of oximeter oxygen saturation data from preterm babies. 早产儿血氧仪血氧饱和度数据统计摘要的探索性研究。

ISRN pediatrics Pub Date : 2011-01-01 Epub Date: 2011-04-26 DOI: 10.5402/2011/296418

Dominic S Lee, Marina Zahari, Glynn Russell, Brian A Darlow, Carl J Scarrott, Marco Reale

{"title":"An exploratory investigation of some statistical summaries of oximeter oxygen saturation data from preterm babies.","authors":"Dominic S Lee, Marina Zahari, Glynn Russell, Brian A Darlow, Carl J Scarrott, Marco Reale","doi":"10.5402/2011/296418","DOIUrl":"https://doi.org/10.5402/2011/296418","url":null,"abstract":"Aim. To explore the potential usefulness of the mean, standard deviation (SD), and coefficient of variation (CV = SD/mean) of oximeter oxygen saturations in the clinical care of preterm babies. Methods. This was an exploratory investigation involving 31 preterm babies at 36 weeks postmenstrual age. All babies were healthy, but two were considered to be clinically unstable and required greater attention. Each baby's oxygen saturations were recorded using an oximeter and summarized by the mean, SD, and CV. The potential usefulness of each measure was assessed by its ability to distinguish the two unstable babies from the others. This was achieved using box plots and hierarchical clustering together with the Calinski-Harabasz (CH) index to quantify clustering performance (higher CH index indicates stronger clustering outcome). Results. The box plots flagged both unstable babies as outliers and none of the other babies. Successful clustering of the stable and unstable babies was achieved using the CV (CH = 72.8) and SD (CH = 63.3) but not with the mean. Conclusion. Taking the box plots and clustering results together, it seems plausible that variability might be more effective than mean level for detecting instability in oxygen saturation in preterm babies and that the combination of variability and level through the CV might be even better.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2011 ","pages":"296418"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2011/296418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30505256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

High-sensitivity C reactive protein: associations with cardiovascular risk factors and tracking in female adolescents and young adults. 高敏感性C反应蛋白:与心血管危险因素的关联及其在女性青少年和年轻人中的追踪

ISRN pediatrics Pub Date : 2011-01-01 Epub Date: 2011-01-24 DOI: 10.5402/2011/707206

John A Morrison, Charles J Glueck, Stephen R Daniels, Ping Wang, Davis M Stroop, Paul S Horn

{"title":"High-sensitivity C reactive protein: associations with cardiovascular risk factors and tracking in female adolescents and young adults.","authors":"John A Morrison, Charles J Glueck, Stephen R Daniels, Ping Wang, Davis M Stroop, Paul S Horn","doi":"10.5402/2011/707206","DOIUrl":"https://doi.org/10.5402/2011/707206","url":null,"abstract":"Objective. We assessed adolescent anthropometry, lipids, insulin, glucose, and blood pressures to identify factors associated with high-sensitivity C-reactive protein (hsCRP) and its tracking in young adults. Methods. Ten-year prospective study of 589 schoolgirls, 321 black, 268 white. Results. HsCRP did not differ (P > .08) by race or oral contraceptive use. HsCRP tracked from age 16 to 25 (r = 0.77), 16 to 26 (r = 0.50), 24 to 26 (r = 0.66), and 25 to 26 (r = 0.71), all P ≤ .02. By stepwise regression, at age 16, waist circumference accounted for 44.8% of hsCRP variance; BMI accounted for 33.1%, 34.4%, and 31.1% at ages 24, 25, and 26, P < .0001 for all. Changes in cholesterol and BMI were associated with change in hsCRP from age 24-26 (partial R(2) = 12.3% P < .0001, 6.6% P = .0012). Changes in BMI and triglyceride (partial R(2) = 8.5% P = .0001, 3.3%, P = .0045) were associated with change in hsCRP from age 25 to 26. Conclusions. HsCRP tracks from age 16 to 26, with BMI, waist circumference, and cholesterol as major determinants.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2011 ","pages":"707206"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2011/707206","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30556938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Knowledge and Practice Gaps among Pediatric Nurses at a Tertiary Care Hospital Karachi Pakistan. 巴基斯坦卡拉奇一家三级医院儿科护士的知识和实践差距。

ISRN pediatrics Pub Date : 2011-01-01 Epub Date: 2011-05-03 DOI: 10.5402/2011/460818

Rozina Roshan Essani, Tazeen Saeed Ali

{"title":"Knowledge and Practice Gaps among Pediatric Nurses at a Tertiary Care Hospital Karachi Pakistan.","authors":"Rozina Roshan Essani, Tazeen Saeed Ali","doi":"10.5402/2011/460818","DOIUrl":"https://doi.org/10.5402/2011/460818","url":null,"abstract":"The advancement in medical science has created health care environments that require nursing professionals who posses specialized clinical knowledge and skills to provide care and deal with critically and acutely ill children. This study explored gaps between knowledge and practice as perceived by the registered nurses of pediatric units by further recommending the changes suggested by them. A descriptive exploratory study design under the quantitative research methodology was utilized using universal sampling of all pediatric nurses working at a tertiary care hospital in Karachi, Pakistan. The gaps between knowledge and practice, as perceived by the participants, were categorized into five major categories: (1) medication (34%), (2) skills (28.3%), (3) knowledge (13.36%), (4) handling of code blue and intubations (12.6%), and (5) operating medical devices (11.58%). As a result, anxiety and incompetency were notably seen in the participants which had great amount of impact on the level of care provided to the patients. The implications of the findings for quality patient care were also analyzed.","PeriodicalId":73521,"journal":{"name":"ISRN pediatrics","volume":"2011 ","pages":"460818"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2011/460818","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30505260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Potential contributors to the canadian pediatric obesity epidemic. 加拿大儿童肥胖流行的潜在因素。

ISRN pediatrics Pub Date : 2011-01-01 Epub Date: 2011-12-05 DOI: 10.5402/2011/917684

Travis Saunders

引用次数: 25