International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition最新文献

IMPROVING THE LONG-TERM DURABILITY OF POLYMERS USED IN BIOMEDICAL APPLICATIONS. 提高生物医学应用中所用聚合物的长期耐久性。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2023-10-01 Epub Date: 2024-02-05 DOI: 10.1115/IMECE2023-112796

Mohammad Motaher Hossain, Ravi Chandra Madasani

{"title":"IMPROVING THE LONG-TERM DURABILITY OF POLYMERS USED IN BIOMEDICAL APPLICATIONS.","authors":"Mohammad Motaher Hossain, Ravi Chandra Madasani","doi":"10.1115/IMECE2023-112796","DOIUrl":"10.1115/IMECE2023-112796","url":null,"abstract":"Hydrophobic surfaces can improve the long-term mechanical response of polymers by delaying their degradation caused by moisture absorption over time. This improvement in long-term mechanical performance can significantly increase the lifespan of polymers used in various biomedical applications, such as total joint replacement prostheses applications. Although a number of surface modification techniques have been developed over the years, such as introduction of various textures on the surface; their specific influences on hydrophobicity enhancement as well as long-term mechanical performance are yet to be fully understood. In this study, surface textures, with variation in type and geometry, are introduced on model Ultrahigh Molecular Weight Polyethylene (UHMWPE) and High Density Polyethylene (HDPE) surfaces to study the effect of surface modification on hydrophobicity and long-term mechanical performance under environmental conditions. The results show that introduction of surface textures significantly improves the hydrophobicity of model polymers. Texture length or diameter significantly affects the improvement in hydrophobicity. However, texture spacing does not have significant influence on the improvement in hydrophobicity. How this improvement in hydrophobicity facilitates improving the long-term mechanical performance under environmental conditions is investigated. The study provides useful guidelines to improve the long-term mechanical response of polymers for various applications, including biomedical applications.","PeriodicalId":73488,"journal":{"name":"International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition","volume":"2023 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11093517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HYDROPHOBICITY IMPROVEMENTS OF POLYMERS USED IN BIOMEDICAL APPLICATIONS. 用于生物医学应用的聚合物的疏水性改进。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2022-10-01 Epub Date: 2023-02-08 DOI: 10.1115/IMECE2022-95610

Mohammad Motaher Hossain, Vinay Reddy Lokasani

{"title":"HYDROPHOBICITY IMPROVEMENTS OF POLYMERS USED IN BIOMEDICAL APPLICATIONS.","authors":"Mohammad Motaher Hossain, Vinay Reddy Lokasani","doi":"10.1115/IMECE2022-95610","DOIUrl":"10.1115/IMECE2022-95610","url":null,"abstract":"Improvement in hydrophobicity is important for polymers used in various applications such as biomedical applications, as it can delay their degradation due to long-term exposure to moisture environments. Although a number of surface modification techniques have been developed over the years to improve hydrophobicity, their specific influences on hydrophobicity enhancement as well as long-term mechanical and tribological performances are yet to be fully understood. In this study, surface textures, with variation in type and geometry, are introduced on Ultrahigh Molecular Weight Polyethylene (UHMWPE) and High Density Polyethylene (HDPE) surfaces to study the effect of surface modification on hydrophobicity and long-term mechanical and tribological performances. Based on the theoretical study using Wenzel and Cassie-Baxter models, surface textures of various types and dimension are introduced on UHMWPE and HDPE surfaces. The results show that introduction of surface textures significantly improves the hydrophobicity of polymers. Specific relationship between texture type and geometry, and improvement in hydrophobicity is explored. Based on the comparison between experimental results and theoretical models, transition state modeling seems to be more suitable in describing the change in hydrophobicity with the addition of surface texture. The study provides useful guidelines to improve hydrophobicity of polymers for biomedical applications.","PeriodicalId":73488,"journal":{"name":"International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition","volume":"2022 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205070/pdf/nihms-1897956.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9522331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUATION OF NEEDLE DRIVER DESIGNS FOR ROBOT-ASSISTED NEEDLE INSERTIONS UNDER MRI GUIDANCE. MRI引导下机器人辅助针头插入的针头驱动器设计评估。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2022-10-01 Epub Date: 2023-02-08 DOI: 10.1115/IMECE2022-96678

Guanyun Liu, Yanzhou Wang, Gang Li, Kevin Cleary, Iulian Iordachita

引用次数: 0

DEMONSTRATION AND EXPERIMENTAL VALIDATION OF PLASTIC-ENCASED RESONANT ULTRASONIC PIEZOELECTRIC ACTUATOR FOR MRI-GUIDED SURGICAL ROBOTS. mri引导手术机器人用塑料封装谐振式超声压电驱动器的演示与实验验证。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2018-11-09 DOI: 10.1115/IMECE2018-87963

P. Carvalho, K. Gandomi, C. Nycz, G. Fischer

{"title":"DEMONSTRATION AND EXPERIMENTAL VALIDATION OF PLASTIC-ENCASED RESONANT ULTRASONIC PIEZOELECTRIC ACTUATOR FOR MRI-GUIDED SURGICAL ROBOTS.","authors":"P. Carvalho, K. Gandomi, C. Nycz, G. Fischer","doi":"10.1115/IMECE2018-87963","DOIUrl":"https://doi.org/10.1115/IMECE2018-87963","url":null,"abstract":"Intra-operative medical imaging based on magnetic resonance imaging (MRI) coupled with robotic manipulation of surgical instruments enables precise feedback-driven procedures. Electrically powered non-ferromagnetic motors based on piezoelectric elements have shown to be well suited for MRI robots. However, even avoiding ferrous materials, the high metal content on commercially available motors still cause distortions to the magnetic fields. We construct semi-custom piezoelectric actuators wherein the quantity of conductive material is minimized and demonstrate that the distortion issues can be partly addressed through substituting several of these components for plastic equivalents, while maintaining motor functionality. Distortion was measured by assessing the RMS change in position of 49 centroid points in a 12.5mm square grid of a gelatin-filled phantom. The metal motor caused a distortion of up to 4.91mm versus 0.55mm for the plastic motor. An additional SNR drop between motor off and motor spinning of approximately 20% was not statistically different for metal versus plastic (p=0.36).","PeriodicalId":73488,"journal":{"name":"International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75691456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A BIOMECHANICAL AND THERMAL ANALYSIS FOR BONE AUGMENTATION OF THE PROXIMAL FEMUR. 股骨近端骨增强的生物力学和热分析。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2018-11-09 DOI: 10.1115/IMECE2018-88583

Amirhossein Farvardin, Mahsan Bakhtiari Nejad, Michael Pozin, M. Armand

引用次数: 3

OCT-BASED THREE DIMENSIONAL MODELING OF STENT DEPLOYMENT. 基于oct的支架部署三维建模。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2017-11-01 DOI: 10.1115/IMECE2017-72146

Pengfei Dong, David Prabhu, David L Wilson, Hiram G Bezerra, Linxia Gu

引用次数: 2

A MULTISCALE COMPUTATIONAL MODEL FOR THE GROWTH OF THE CRANIAL VAULT IN CRANIOSYNOSTOSIS. 颅缝闭合症颅穹窿生长的多尺度计算模型。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2014-11-01 DOI: 10.1115/IMECE2014-38728

Chanyoung Lee, Joan T Richtsmeier, Reuben H Kraft

引用次数: 3

INSIGHTS INTO THE MECHANICS OF CYTOKINETIC RING ASSEMBLY USING 3D MODELING. 洞察使用3d建模的细胞动力学环组装的力学。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2014-01-01 DOI: 10.1115/IMECE2014-39006

Tamara Carla Bidone, Haosu Tang, Dimitrios Vavylonis

{"title":"INSIGHTS INTO THE MECHANICS OF CYTOKINETIC RING ASSEMBLY USING 3D MODELING.","authors":"Tamara Carla Bidone, Haosu Tang, Dimitrios Vavylonis","doi":"10.1115/IMECE2014-39006","DOIUrl":"https://doi.org/10.1115/IMECE2014-39006","url":null,"abstract":"During fission yeast cytokinesis, actin filaments nucleated by cortical formin Cdc12 are captured by myosin motors bound to a band of cortical nodes. The myosin motors exert forces that pull nodes together into a contractile ring. Cross-linking interactions help align actin filaments and nodes into a single bundle. Mutations in the myosin motor domain and changes in the concentration of cross-linkers alpha-actinin and fimbrin alter the morphology of the condensing network, leading to clumps, rings or extended meshworks. How the contractile tension developing during ring formation depends on the interplay between network morphology, myosin motor activity, cross-linking and actin filament turnover remains to be elucidated. We addressed this question using a 3D computational model in which semiflexible actin filaments (represented as beads connected by springs) grow from formins, can be captured by myosin in neighboring nodes, and get cross-linked with one another through an attractive interaction. We identify regimes of tension generation between connected nodes under a wide set of conditions regarding myosin dynamics and strength of cross-linking between actin filaments. We find conditions that maximize circumferential tension, correlate them with network morphology and propose experiments to test these predictions. This work addresses \"Morphogenesis of soft and living matter\" using computational modeling to simulate cytokinetic ring assembly from the key molecular mechanisms of viscoelastic cross-linked actin networks that include active molecular motors.","PeriodicalId":73488,"journal":{"name":"International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition","volume":"9 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/IMECE2014-39006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33191560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SIMULATION OF DISCRETE BLOOD VESSEL EFFECTS ON THE THERMAL SIGNATURE OF A MELANOMA LESION. 离散血管效应对黑素瘤病变热特征的模拟。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2013-01-01 DOI: 10.1115/IMECE2013-64451

Sri Kamal Kandala, Daxiang Deng, Cila Herman

{"title":"SIMULATION OF DISCRETE BLOOD VESSEL EFFECTS ON THE THERMAL SIGNATURE OF A MELANOMA LESION.","authors":"Sri Kamal Kandala, Daxiang Deng, Cila Herman","doi":"10.1115/IMECE2013-64451","DOIUrl":"https://doi.org/10.1115/IMECE2013-64451","url":null,"abstract":"The effect of the underlying blood vessel on the transient thermal response of the skin surface with and without a melanoma lesion is studied. A 3D computational model of the layers of the skin tissue with cancerous lesion was developed in COMSOL software package. Heat transfer in the skin layers and the lesion is governed by the Pennes bio-heat equation, while the blood vessel is modeled as fully developed pipe flow with constant heat transfer coefficient. The effect of various pertinent parameters, such as diameter of the blood vessel, lateral location of the blood vessel relative to the lesion, flow velocity of the blood, on the skin surface temperature distribution, have been studied in the paper. The results show significant influence of the underlying blood vessel on the temperature of the skin surface and lesion as well as on the surrounding healthy tissue. Thus, a need for development of evaluation criteria for detection of malignant lesions in the presence of blood vessels is is discussed.","PeriodicalId":73488,"journal":{"name":"International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition","volume":"3B ","pages":"V03BT03A038-V03BT03A044"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/IMECE2013-64451","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32759080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Third-Order Muscle Models: The Role of Oscillatory Behavior In Force Control. 三阶肌肉模型:振动行为在力控制中的作用。

International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition Pub Date : 2012-11-01 DOI: 10.1115/IMECE2012-88081

Davide Piovesan, Alberto Pierobon, Ferdinando A Mussa-Ivaldi

{"title":"Third-Order Muscle Models: The Role of Oscillatory Behavior In Force Control.","authors":"Davide Piovesan, Alberto Pierobon, Ferdinando A Mussa-Ivaldi","doi":"10.1115/IMECE2012-88081","DOIUrl":"https://doi.org/10.1115/IMECE2012-88081","url":null,"abstract":"This paper presents the analysis of a third-order linear differential equation representing a muscle-tendon system, including the identification of critical damping conditions. We analytically verified that this model is required for a faithful representation of muscle-skeletal muscles and provided numerical examples using the biomechanical properties of muscles and tendon reported in the literature. We proved the existence of a theoretical threshold for the ratio between tendon and muscle stiffness above which critical damping can never be achieved, thus resulting in an oscillatory free response of the system, independently of the value of the damping. Oscillation of the limb can be compensated only by active control, which requires creating an internal model of the limb mechanics. We demonstrated that, when admissible, over-damping of the muscle-tendon system occurs for damping values included within a finite interval between two separate critical limits. The same interval is a semi-infinite region in second-order models. Moreover, an increase in damping beyond the second critical point rapidly brings the system to mechanical instability.","PeriodicalId":73488,"journal":{"name":"International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition","volume":"2 ","pages":"493-501"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1115/IMECE2012-88081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34303045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8