International journal of physical medicine & rehabilitation最新文献

{"title":"Positive Effect of Impairment-Oriented Training on N-Acetylaspartate Levels of Ipsilesional Motor Cortex in Subcortical Stroke: A Case Study.","authors":"Ali Ahmed, C. Cirstea","doi":"10.4172/2329-9096.1000325","DOIUrl":"https://doi.org/10.4172/2329-9096.1000325","url":null,"abstract":"BACKGROUND AND PURPOSE\u0000We investigated the effects of an intensive impairment-oriented training on neuronal state (assessed by proton MR spectroscopy, 1H-MRS) of the spared motor and premotor cortices in the injured (ipsilesional) hemisphere and clinical impairment in a patient with chronic subcortical stroke.\u0000\u0000\u0000METHODS\u0000One survivor of a single ischemic stroke located outside of the motor and premotor cortices (assessed on T1-weighted MRI) was studied at six months after stroke. We used functional MRI-guided 1H-MRS to quantify the levels of N-acetylaspartate (NAA - a putative neuronal marker) in the hand representation within ipsilesional primary motor cortex (M1), dorsal premotor cortex (dPM) and supplementary motor area (SMA), and Fugl-Meyer (normal=66 points) test to assess the arm motor impairment immediately before and after a motor training paradigm. Training comprised intensive variable practice (1080 repetitions over 12 day-period) of a reach-to-grasp task with the impaired hand while focusing the learner's attention on an altered movement component, i.e., decreased elbow extension.\u0000\u0000\u0000RESULTS\u0000At baseline, the patient was severely impaired (Fugl-Meyer score=25 points) and exhibited lower level of NAA in all areas (M1, 9.2 mM vs. 11.6 ± 2.0 mM in healthy controls; dPM, 8.9 mM vs. 12.2 ± 1.9 mM; SMA, 7.4 mM vs. 11.0 ± 2.3 mM). After training, the patient improved clinically (by 6 points) and displayed higher levels of NAA across all areas (by 0.6-3.3 mM).\u0000\u0000\u0000CONCLUSIONS\u0000Our data demonstrated that the radiologically normal-appearing ipsilesional motor and premotor areas have the resources to boost behavioral output in response to an intervention. We hope that these data will act as a starting point for further research to test the potential of 1H-MRS measures to provide a biomarker of neuroplasticity in response to restorative therapies in chronic stroke.","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9096.1000325","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70279087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Balance Deficits in People with Parkinson Disease; is the Sensory Organization Test Enough?","authors":"G. Gera, DL Freeman, MT Blackinton, F. Horak, L. King","doi":"10.4172/2329-9096.1000322","DOIUrl":"https://doi.org/10.4172/2329-9096.1000322","url":null,"abstract":"Background and Purpose Balance deficits in people with Parkinson’s disease can affect any of the multiple systems encompassing balance control. Thus, identification of the specific deficit is crucial in customizing balance rehabilitation. The sensory organization test, a test of sensory integration for balance control, is sometimes used in isolation to identify balance deficits in people with Parkinson’s disease. More recently, the Mini-Balance Evaluations Systems Test, a clinical scale that tests multiple domains of balance control, has begun to be used to assess balance in patients with Parkinson’s disease. The purpose of our study was to compare the use of Sensory Organization Test and Mini-Balance Evaluations Systems Test in identifying balance deficits in people with Parkinson’s disease. Methods 45 participants (27M, 18F; 65.2 ± 8.2 years) with idiopathic Parkinson’s disease participated in the cross-sectional study. Balance assessment was performed using the Sensory Organization Test and the Mini-Balance Evaluations Systems Test. People were classified into normal and abnormal balance based on the established cutoff scores (normal balance: Sensory Organization Test >69; Mini-Balance Evaluations Systems Test >73). Results More subjects were classified as having abnormal balance with the Mini-Balance Evaluations Systems Test (71% abnormal) than with the Sensory Organization Test (24% abnormal) in our cohort of people with Parkinson’s disease. There were no subjects with a normal Mini-Balance Evaluations Systems Test score but abnormal Sensory Organization Test score. In contrast, there were 21 subjects who had an abnormal Mini-Balance Evaluations Systems Test score but normal Sensory Organization Test scores. Discussion and Conclusions Findings from this study suggest that investigation of sensory integration deficits, alone, may not be able to identify all types of balance deficits found in patients with Parkinson’s disease. Thus, a comprehensive approach should be used to test of multiple balance systems to provide customized rehabilitation.","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9096.1000322","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70279544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review of Cerebral Palsy Registries/Surveillance Groups: Relationships between Registry Characteristics and Knowledge Dissemination.","authors":"Donna S Hurley, Theresa Sukal-Moulton, Deborah Gaebler-Spira, Kristin J Krosschell, Larissa Pavone, Akmer Mutlu, Julius Pa Dewald, Michael E Msall","doi":"10.4172/2329-9096.1000266","DOIUrl":"10.4172/2329-9096.1000266","url":null,"abstract":"<p><p>The aims of this study were to provide a comprehensive summary of the body of research disseminated by Cerebral Palsy (CP) registries and surveillance programs from January 2009 through May 2014 in order to describe the influence their results have on our overall understanding of CP. Secondly, registries/surveillance programs and the work they produced were evaluated and grouped using standardized definitions and classification systems.</p><p><strong>Method: </strong>A systematic review search in PubMed, CINAH and Embase for original articles published from 1 January 2009 to 20 May 2014 originating from or supported by population based CP registries and surveillance programs or population based national registries including CP were included. Articles were grouped by 2009 World CP Registry Congress aim, registry/surveillance program classification, geographical region, and the International Classification of Function, Disability and Health (ICF) domain. Registry variables were assessed using the ICF-CY classification.</p><p><strong>Results: </strong>Literature searches returned 177 articles meeting inclusion criteria. The majority (69%) of registry/surveillance program productivity was related to contributions as a Resource for CP Research. Prevention (23%) and Surveillance (22%) articles were other areas of achievement, but fewer articles were published in the areas of Planning (17%) and Raising the Profile of CP (2%). There was a range of registry/surveillance program classifications contributing to this productivity, and representation from multiple areas of the globe, although most of the articles originated in Europe, Australia, and Canada. The domains of the ICF that were primarily covered included body structures and function at the early stages of life. Encouragingly, a variety of CP registry/surveillance program initiatives included additional ICF domains of participation and environmental and personal factors.</p><p><strong>Interpretation: </strong>CP registries and surveillance programs, including novel non-traditional ones, have significantly contributed to the understanding of how CP affects individuals, families and society. Moving forward, the global CP registry/surveillance program community should continue to strive for uniformity in CP definitions, variables collected and consistency with international initiatives like the ICF so that databases can be consolidated for research use. Adaptation to new technologies can improve access, reduce cost and facilitate information transfer between registrants, researchers and registries/surveillance programs. Finally, increased efforts in documenting variables of individuals with CP into adulthood should be made in order to expand our understanding of CP across the lifespan.</p>","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70279458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Link between Musculoskeletal Pain, Lifestyle Behaviors, Exercise Self-Efficacy, and Quality of Life in Overweight and Obese Individuals.","authors":"Pouran D Faghri,&nbsp;Winnie Sy Chin,&nbsp;Tania B Huedo-Medina","doi":"10.4172/2329-9096.1000255","DOIUrl":"https://doi.org/10.4172/2329-9096.1000255","url":null,"abstract":"<p><strong>Objective: </strong>To determine the extent musculoskeletal (MS) pain in the low back and knee (weight-bearing (WB) joints), shoulder and wrist (non-weight bearing joints), and exercise self-efficacy mediates associations between overweight and obesity levels based on BMI (4 levels: overweight, obese class I, II, or III), physical function, emotional role, social interference, and physical activity (PA) levels.</p><p><strong>Design: </strong>Cross-sectional study.</p><p><strong>Setting: </strong>Four long-term nursing home facilities in the Northeast U.S.</p><p><strong>Participants: </strong>99 overweight or obese (BMI > 25) nursing home employees.</p><p><strong>Interventions: </strong>Self-reported survey administered to employees who met inclusion and exclusion criteria.</p><p><strong>Main outcome measures: </strong>General health status, physical function, emotional role, Exercise Self-Efficacy Scale (ESE), physical activity (PA), and frequency of pain at each joint.</p><p><strong>Results: </strong>Reported pain frequency were 66.3%, 54.4%, 42.2%, and 24.1% for lower back, knee, shoulder, and wrist, respectively. Higher obesity levels were associated with lower physical function (r=-0.109, p=0.284). PA decreased with higher obesity levels (r=-0.248, p<0.05), particularly in moderate PA (r=-0.293, p<0.05). Obesity was associated with a lower ESE (r=-0.239, p<0.05). Wrist pain significantly mediated the effect of obesity on moderate physical function, emotional role, and ESE. ESE was a significant mediator between obesity and moderate and vigorous PA.</p><p><strong>Conclusions: </strong>Overweight and obese nursing home employees are at higher risk for developing musculoskeletal disorders due to high demand, low control jobs, and the associated biomedical compromises while working. To increase the effectiveness of weight loss interventions for this population, the mediating effects of MS pain with higher levels of obesity should be considered.</p>","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9096.1000255","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35664455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Semantic Encoding Strategy Training after Traumatic Brain Injury is Correlated with Frontal Brain Activation Change.","authors":"Rebecca J Lepping, William M Brooks, Brenda A Kirchhoff, Laura E Martin, Monica Kurylo, Linda Ladesich, Jo Ann Lierman, George Varghese, Cary R Savage","doi":"10.4172/2329-9096.1000254","DOIUrl":"10.4172/2329-9096.1000254","url":null,"abstract":"<p><strong>Background: </strong>Traumatic Brain Injury (TBI) is frequently associated with chronic, treatment-resistant memory problems, and is one of the leading causes of disability in otherwise healthy adults. Cognitive rehabilitation therapies are used with the goal of improving memory functioning; however, not all patients benefit. Prefrontal cortex (PFC) is critical for employing effective memory strategies. We hypothesized that memory improvement after a brief cognitive intervention would be associated with increases in PFC activation during a memory task.</p><p><strong>Methods: </strong>The current study used behavioral analyses and functional magnetic resonance imaging (fMRI) to examine the effects of two days of intensive semantic encoding strategy training on memory performance and brain activation patterns in patients in the post-acute stage of TBI. fMRI data were collected before and after training while participants learned word lists.</p><p><strong>Results: </strong>Post-training vs. pre-training changes in total recall and semantic clustering during recall were positively correlated with post-training vs. pre-training changes in neural activation in PFC.</p><p><strong>Conclusions: </strong>These results suggest that variability in treatment response to cognitive training after TBI may be due in part to variability in PFC function, and that some survivors of TBIs may benefit from treatments specifically targeting the PFC.</p>","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38296279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality and Quantity of Rehabilitation Exercises Delivered By A 3-D Motion Controlled Camera: A Pilot Study","authors":"R. Komatireddy, A. Chokshi, Jeanna Basnett, Michael Casale, D. Goble, T. Shubert","doi":"10.4172/2329-9096.1000214","DOIUrl":"https://doi.org/10.4172/2329-9096.1000214","url":null,"abstract":"Introduction Tele-rehabiliation technologies that track human motion could enable physical therapy in the home. To be effective, these systems need to collect critical metrics without PT supervision both in real time and in a store and forward capacity. The first step of this process is to determine if PTs (PTs) are able to accurately assess the quality and quantity of an exercise repetition captured by a tele-rehabilitation platform. The purpose of this pilot project was to determine the level of agreement of quality and quantity of an exercise delivered and assessed by the Virtual Exercise Rehabilitation Assistant (VERA), and seven PTs. Methods Ten healthy subjects were instructed by a PT in how to perform four lower extremity exercises. Subjects then performed each exercises delivered by VERA which counted repetitions and quality. Seven PTs independently reviewed video of each subject’s session and assessed repetitions quality. The percent difference in total repetitions and analysis of the distribution of rating repetition quality was assessed between the VERA and PTs. Results The VERA counted 426 repetitions across 10 subjects performing the four different exercises while the mean repetition count from the PT panel was 426.7 (SD = 0.8). The VERA underestimated the total repetitions performed by 0.16% (SD = 0.03%, 95% CI 0.12 – 0. 22). Chi square analysis across raters was χ2 = 63.17 (df = 6, p<.001), suggesting significant variance in at least one rater. Conclusion The VERA count of repetitions was accurate in comparison to a seven member panel of PTs. For exercise quality the VERA was able to rate 426 exercise repetitions across 10 patients and four different exercises in a manner consistent with five out of seven experienced PTs.","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9096.1000214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70279441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in Delivery and Exercise Content of Physical Therapy Rehabilitation Following Total Knee Replacement Surgery: A Cross-Sectional Observation Study","authors":"C. Oatis, Wenjun Li, Jessica M. DiRusso, Mindy J. Hoover, K. K. Johnston, Monika K. Butz, A. Phillips, Kimberly M. Nanovic, Elizabeth C. Cummings, M. Rosal, D. Ayers, P. Franklin","doi":"10.4172/2329-9096.S5-002","DOIUrl":"https://doi.org/10.4172/2329-9096.S5-002","url":null,"abstract":"Objective Prevalence of total knee replacement (TKR) is large and growing but functional outcomes are variable. Physical therapy (PT) is integral to functional recovery following TKR but little is known about the quantity or content of PT delivered. Purposes of this study were to describe the amount and exercise content of PT provided in the terminal episode of PT care following TKR and to examine factors associated with utilization and content. Methods Subjects included participants in a clinical trial of behavioral interventions for patients undergoing primary unilateral TKR who had completed the 6-month study evaluation. PT records were requested from 142 consecutive participants who had completed their post-TKR rehabilitation, 102 in/out patient care, and 40 in homecare. Information on utilization and exercises was extracted from a retrospective review of the PT records. Results We received 90 (88%) outpatient and 27 (68%) homecare PT records. Records showed variability in timing, amount and content of PT. Patients receiving outpatient PT had more visits and remained in PT longer (p<0.001). Exercises known in the TKR literature were utilized more frequently in the outpatient setting (p=0.001) than in home care. Records from both settings had limited documentation of strengthening progression. Conclusions The study reveals considerable variability in timing, utilization and exercise content of PT following TKR and suggests sub-optimal exercise for strengthening. While methods we employed document variability, improved systematic PT documentation and in-depth research are needed to identify optimal timing, utilization and content of PT following TKR.","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-9096.S5-002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70279166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Scalable Monitoring System for Wheelchair Tilt-in-Space Usage.","authors":"Tim D Yang, Seth A Hutchinson, Laura A Rice, Kenneth L Watkin, Yih-Kuen Jan","doi":"10.4172/jpmr.1000129","DOIUrl":"10.4172/jpmr.1000129","url":null,"abstract":"","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190843/pdf/nihms490442.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32742700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal Cord Injury and Osteoporosis: Causes, Mechanisms, and Rehabilitation Strategies","authors":"C. Tan, R. Battaglino, L. Morse","doi":"10.4172/2329-9096.1000127","DOIUrl":"https://doi.org/10.4172/2329-9096.1000127","url":null,"abstract":"Spinal cord injury (SCI) has a huge impact on the individual, society and the economy. Though advances in acute care resulted in greatly reduced co-morbidities, there has been much less progress preventing long-term sequelae of SCI. Among the long-term consequences of SCI is bone loss (osteoporosis) due to the mechanical unloading of the paralyzed limbs and vascular dysfunction below the level of injury. Though osteoporosis may be partially prevented via pharmacologic interventions during the acute post-injury phase, there are no clinical guidelines to treat osteoporosis during the chronic phase. Thus there is need for scientific advances to improve the rehabilitative approaches to SCI-related osteoporosis. Recent advances in application of a new technology, functional electrical stimulation, provide a new and exciting opportunity to improve bone metabolism and to provide mechanical strain to the paralyzed lower limbs sufficient to stimulate new bone formation in individuals with SCI. The purpose of this minireview is to delineate our current understanding of SCI-related osteoporosis and to highlight recent literature towards its prevention and treatment.","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70279387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal Cord Injury and Osteoporosis: Causes, Mechanisms, and Rehabilitation Strategies.","authors":"Can Ozan Tan,&nbsp;Ricardo A Battaglino,&nbsp;Leslie R Morse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Spinal cord injury (SCI) has a huge impact on the individual, society and the economy. Though advances in acute care resulted in greatly reduced co-morbidities, there has been much less progress preventing long-term sequelae of SCI. Among the long-term consequences of SCI is bone loss (osteoporosis) due to the mechanical unloading of the paralyzed limbs and vascular dysfunction below the level of injury. Though osteoporosis may be partially prevented via pharmacologic interventions during the acute post-injury phase, there are no clinical guidelines to treat osteoporosis during the chronic phase. Thus there is need for scientific advances to improve the rehabilitative approaches to SCI-related osteoporosis. Recent advances in application of a new technology, functional electrical stimulation, provide a new and exciting opportunity to improve bone metabolism and to provide mechanical strain to the paralyzed lower limbs sufficient to stimulate new bone formation in individuals with SCI. The purpose of this minireview is to delineate our current understanding of SCI-related osteoporosis and to highlight recent literature towards its prevention and treatment.</p>","PeriodicalId":73470,"journal":{"name":"International journal of physical medicine & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32835044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}