Intensive care medicine. Paediatric and neonatal最新文献

{"title":"Sensitivity of ICD coding for sepsis in children-a population-based study.","authors":"Olga Endrich,&nbsp;Karen Triep,&nbsp;Luregn J Schlapbach,&nbsp;Klara M Posfay-Barbe,&nbsp;Ulrich Heininger,&nbsp;Eric Giannoni,&nbsp;Martin Stocker,&nbsp;Anita Niederer-Loher,&nbsp;Christian R Kahlert,&nbsp;Giancarlo Natalucci,&nbsp;Christa Relly,&nbsp;Thomas Riedel,&nbsp;Christoph Aebi,&nbsp;Christoph Berger,&nbsp;Philipp K A Agyeman","doi":"10.1007/s44253-023-00006-1","DOIUrl":"https://doi.org/10.1007/s44253-023-00006-1","url":null,"abstract":"<p><strong>Background: </strong>International Classification of Diseases 10th edition (ICD-10) is widely used to describe the burden of disease.</p><p><strong>Aim: </strong>To describe how well ICD-10 coding captures sepsis in children admitted to the hospital with blood culture-proven bacterial or fungal infection and systemic inflammatory response syndrome.</p><p><strong>Methods: </strong>Secondary analysis of a population-based, multicenter, prospective cohort study on children with blood culture-proven sepsis of nine tertiary pediatric hospitals in Switzerland. We compared the agreement of validated study data on sepsis criteria with ICD-10 coding abstraction obtained at the participating hospitals.</p><p><strong>Results: </strong>We analyzed 998 hospital admissions of children with blood culture-proven sepsis. The sensitivity of ICD-10 coding abstraction was 60% (95%-CI 57-63) for sepsis; 35% (95%-CI 31-39) for sepsis with organ dysfunction, using an explicit abstraction strategy; and 65% (95%-CI 61-69) using an implicit abstraction strategy. For septic shock, the sensitivity of ICD-10 coding abstraction was 43% (95%-CI 37-50). Agreement of ICD-10 coding abstraction with validated study data varied by the underlying infection type and disease severity (<i>p</i> < 0.05). The estimated national incidence of sepsis, inferred from ICD-10 coding abstraction, was 12.5 per 100,000 children (95%-CI 11.7-13.5) and 21.0 per 100,000 children (95%-CI 19.8-22.2) using validated study data.</p><p><strong>Conclusions: </strong>In this population-based study, we found a poor representation of sepsis and sepsis with organ dysfunction by ICD-10 coding abstraction in children with blood culture-proven sepsis when compared against a prospective validated research dataset. Sepsis estimates in children based on ICD-10 coding may thus severely underestimate the true prevalence of the disease.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s44253-023-00006-1.</p>","PeriodicalId":73402,"journal":{"name":"Intensive care medicine. Paediatric and neonatal","volume":"1 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9713556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}