Integrative physiological and behavioral science : the official journal of the Pavlovian Society最新文献_第3页

An acute stressor enhances sensitivity to a chemical irritant and increases 51CrEDTA permeability of the colon in adult rats. 急性应激源增强成年大鼠对化学刺激物的敏感性，并增加结肠51CrEDTA的通透性。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2005-01-01 DOI: 10.1007/BF02734187

Anne Marita Milde, Gülen Arslan, J Bruce Overmier, Arnold Berstad, Robert Murison

{"title":"An acute stressor enhances sensitivity to a chemical irritant and increases 51CrEDTA permeability of the colon in adult rats.","authors":"Anne Marita Milde, Gülen Arslan, J Bruce Overmier, Arnold Berstad, Robert Murison","doi":"10.1007/BF02734187","DOIUrl":"https://doi.org/10.1007/BF02734187","url":null,"abstract":"We investigated the effect of prior acute stress on colonic permeability induced by a chemical irritant known to induce symptoms similar to inflammatory bowel disease in rodents. Adult male rats (n = 12) were stressed by a single session of ten unpredictable, uncontrollable foot shocks, and half were home cage controls (n = 12). Twenty-nine days later, half of each treatment group was exposed to 4% DSS (dextran sulphate sodium) solution in their drinking water for 48 hours while half received pure water over two periods separated by 17 days. After food deprivation overnight and light isoflurane anaesthesia the following morning, the animals were given a colonic infusion of 2000 nCi (nanocurie) 51CrEDTA (51Cr-labelled ethylenediaminetetraacetic acid) and then placed individually in metabolic cages for a six hours continuous urine collection. Radioactivity in urine was measured by a gamma counter and percentage recovery of 51CrEDTA calculated as an indicator of colonic mucosal permeability. Results concluded that pre-shocked animals exposed to DSS showed significantly higher mucosal permeability than the pre-shocked animals given water, and the non-shocked animals given either DSS or water. Pre-shock in combination with two exposures to a chemical irritant separated by 17 days had a pronounced effect on colonic permeability, indicating that stress should be considered a possible initiating or contributory factor to increased intestinal permeability related to a mucosal challenge.","PeriodicalId":73397,"journal":{"name":"Integrative physiological and behavioral science : the official journal of the Pavlovian Society","volume":"40 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02734187","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9158920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Effects of emotional valence and arousal manipulation on eyeblink classical conditioning and autonomic measures. 情绪效价和唤醒操纵对眨眼经典条件反射和自主测量的影响。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2005-01-01 DOI: 10.1007/BF02734188

Jo Anne Tracy, Richard M McFall, Joseph E Steinmetz

引用次数: 5

The effects of phenytoin on the performance of rats in a delayed match-to-place task. 苯妥英对大鼠延迟匹配-位置任务表现的影响。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2005-01-01 DOI: 10.1007/BF02734185

D L Samuelson, L L Arnold, T M Mowery, N A Mesnard, P E Garraghty

引用次数: 4

Autonomic activity, pain, and perceived health in patients on sick leave due to stress-related illnesses. 由于压力相关疾病而请病假的病人的自主神经活动、疼痛和感知健康。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2005-01-01 DOI: 10.1007/BF02734184

Marina Heiden, Margareta Barnekow-Bergkvist, Minori Nakata, Eugene Lyskov

{"title":"Autonomic activity, pain, and perceived health in patients on sick leave due to stress-related illnesses.","authors":"Marina Heiden, Margareta Barnekow-Bergkvist, Minori Nakata, Eugene Lyskov","doi":"10.1007/BF02734184","DOIUrl":"https://doi.org/10.1007/BF02734184","url":null,"abstract":"Objective: The aim of the present study was to compare autonomic activity, pressure-pain thresholds, and subjective assessments of health and behavior between patients with stress-related illnesses and healthy control subjects.Methods: Twenty sick-listed patients with stress-related illnesses and 20 age- and gender-matched healthy subjects performed tests of autonomic regulation and algometric tests, and completed questionnaires about physical and mental health and behavioral patterns.Results: Patients exhibited higher autonomic reactivity to cognitive and physical laboratory tasks (p < 0.05), and had lower pressure-pain thresholds in the shoulders and lower back than healthy control subjects (p < 0.05). Furthermore, the patients rated considerably poorer health and health behavior than the control subjects (p < 0.05).Conclusions: The results indicate an engagement of the autonomic nervous system in stress-related illnesses. Furthermore, they show that patients with stress-related illnesses experience symptoms of musculoskeletal pain, and it is therefore recommended that assessments of musculoskeletal pain be incorporated in the clinical examinations and the rehabilitation of patients with stress-related illnesses.","PeriodicalId":73397,"journal":{"name":"Integrative physiological and behavioral science : the official journal of the Pavlovian Society","volume":"40 1","pages":"3-16"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02734184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9457821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Is there a link between Irritable Bowel Syndrome and left-handedness?: An exploratory study. 肠易激综合症和左撇子之间有联系吗?一项探索性研究。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2005-01-01 DOI: 10.1007/BF02734189

Christine P Dancey, E A Attree, György Bàrdos, Agota Kovacs

{"title":"Is there a link between Irritable Bowel Syndrome and left-handedness?: An exploratory study.","authors":"Christine P Dancey, E A Attree, György Bàrdos, Agota Kovacs","doi":"10.1007/BF02734189","DOIUrl":"https://doi.org/10.1007/BF02734189","url":null,"abstract":"Recent research has found that people with Irritable Bowel Syndrome (IBS) and those with Inflammatory Bowel Disease (IBD) show a relative deficit in verbal IQ, compared to their own performance IQ, and the IQ of a healthy comparison group. It has been suggested that the elevated prevalence of left-handedness shown in previous studies investigating people with IBD is due to compromised left-hemisphere development. This may be associated with a decrement in certain cognitive functions such as verbal IQ. A shift in brain dominance from left to right has been found in many atopic and immunological diseases as well as in autonomic dysfunctions. It was uncertain whether this would apply to people with IBS, a functional disorder in which the cause or causes remain unclear. Therefore, the aim of this preliminary study was to investigate whether people with IBS have an increased prevalence of left-handedness. It was found that there was an association between IBS and left-handedness, showing that further research on this association both in IBS and other functional disorders (as well as on the similarities between IBS and IBD) is warranted.","PeriodicalId":73397,"journal":{"name":"Integrative physiological and behavioral science : the official journal of the Pavlovian Society","volume":"40 1","pages":"55-9"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02734189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9457390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Leverpress escape/avoidance training increases neurotrophin levels in rat brain. 杠杆逃避/回避训练增加大鼠脑中的神经营养物质水平。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2005-01-01 DOI: 10.1007/BF02734186

David S Albeck, Kevin D Beck, Ling-Hsuan Kung, Kazuhiro Sano, Francis X Brennan

{"title":"Leverpress escape/avoidance training increases neurotrophin levels in rat brain.","authors":"David S Albeck, Kevin D Beck, Ling-Hsuan Kung, Kazuhiro Sano, Francis X Brennan","doi":"10.1007/BF02734186","DOIUrl":"https://doi.org/10.1007/BF02734186","url":null,"abstract":"In addition to their well-known role in neural development, the neurotrophins BDNF and NGF help mediate the plasticity that occurs in the brain to promote learning. Exposure to learning procedures often leads to increases in neurotrophins, while exposure to stress often results in decreases. It is unclear how the neurotrophins would respond to an aversive learning task. Therefore, BDNF and NGF content in the dorsal striatum, hippocampus, and basal forebrain was measured following discrete trial lever-press escape/avoidance conditioning. Conditioning significantly increased levels of both neurotrophins in hippocampus and basal forebrain, relative to home cage controls (HCC). Contrary to expectations, the dorsal striatum did not show any significant changes. However, significant correlations were observed between dorsal striatal neurotrophins and aspects of avoidance performance. This may indicate that the dorsal striatum is involved in the performance aspects of the task. Results are discussed in terms of the role of neurotrophins in the acquisition of new information, and the neural structures involved in different types of memory.","PeriodicalId":73397,"journal":{"name":"Integrative physiological and behavioral science : the official journal of the Pavlovian Society","volume":" ","pages":"28-34"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02734186","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25866205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Effects of lipopolysaccharide on consolidation of partial learning in the Y-maze. 脂多糖对y型迷宫部分学习巩固的影响。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2004-10-01 DOI: 10.1007/BF02734171

John Michael Holden, J Bruce Overmier, Elizabeth Todd Cowan, Lisa Matthews

引用次数: 18

The classical origins of Pavlov's conditioning. 巴甫洛夫条件反射的经典起源。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2004-10-01 DOI: 10.1007/BF02734167

Robert E Clark

引用次数: 42

Fear develops to the conditioned stimulus and to the context during classical eyeblink conditioning in rats. 在大鼠经典眨眼条件反射过程中，恐惧向条件刺激和情境发展。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2004-10-01 DOI: 10.1007/BF02734168

Gabrielle B Britton, Lori B Astheimer

{"title":"Fear develops to the conditioned stimulus and to the context during classical eyeblink conditioning in rats.","authors":"Gabrielle B Britton, Lori B Astheimer","doi":"10.1007/BF02734168","DOIUrl":"https://doi.org/10.1007/BF02734168","url":null,"abstract":"In classical eyeblink conditioning, non-specific emotional responses to the aversive shock unconditioned stimulus (US), which are presumed to coincide with the development of fear, occur early in conditioning and precede the emergence of eyeblink responses. This two-process learning model was examined by concurrently measuring fear and eyeblink conditioning in the freely moving rat. Freezing served as an index of fear in animals and was measured during the inter-trial intervals in the training context and during a tone conditioned stimulus (CS) presented in a novel context. Animals that received CS-US pairings exhibited elevated levels of fear to the context and CS early in training that decreased over sessions, while eyeblink conditioned responses (CRs) developed gradually during acquisition and decreased during extinction. Random CS-US presentations produced a similar pattern of fear responses to the context and CS as paired presentations despite low eyeblink CR percentages, indicating that fear responding was decreased independent of high levels of learned eyeblink responding. The results of paired training were consistent with two-process models of conditioning that postulate that early emotional responding facilitates subsequent motor learning, but measures from random control animals demonstrate that partial CS-US contingencies produce decrements in fear despite low levels of eyeblink CRs. These findings suggest a relationship between CS-US contingency and fear levels during eyeblink conditioning, and may serve to clarify further the role that fear conditioning plays in this simple paradigm.","PeriodicalId":73397,"journal":{"name":"Integrative physiological and behavioral science : the official journal of the Pavlovian Society","volume":" ","pages":"295-306"},"PeriodicalIF":0.0,"publicationDate":"2004-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02734168","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25695548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Amygdala and periaqueductal gray lesions only partially attenuate unconditional defensive responses in rats exposed to a cat. 杏仁核和导水管周围灰质损伤仅部分减弱猫对大鼠的无条件防御反应。

Integrative physiological and behavioral science : the official journal of the Pavlovian Society Pub Date : 2004-10-01 DOI: 10.1007/BF02734170

Beatrice M de Oca, Michael S Fanselow

{"title":"Amygdala and periaqueductal gray lesions only partially attenuate unconditional defensive responses in rats exposed to a cat.","authors":"Beatrice M de Oca, Michael S Fanselow","doi":"10.1007/BF02734170","DOIUrl":"https://doi.org/10.1007/BF02734170","url":null,"abstract":"Defensive responses to a cat were observed in rats given excitotoxic lesions of the central nucleus of the amygdala (ACe), dorsolateral periaqueductal gray (dlPAG), ventral periaqueductal gray (vPAG), or sham lesions. Rats were placed adjacent to a compartment containing a cat. Sham-lesioned rats avoided the area nearest the cat and preferred the area furthest away from the cat. They also exhibited numerous defensive responses including, climbing, escape from the apparatus, and freezing. Rats with lesions of the ACe reacted like the sham lesioned rats by preferring the area of the apparatus furthest from the cat, however they climbed and escaped significantly less than sham lesioned rats. Avoidance of the area adjacent to the cat was attenuated in rats with lesions of the vPAG. Climbing along the walls of the apparatus was also attenuated in rats with lesions of the vPAG. Escapes from the apparatus were not significantly reduced by lesions of the vPAG and dlPAG. Thus, ACe lesions attenuated climbing and eliminated escapes, but did not impair locomotion of the rat away from the cat.","PeriodicalId":73397,"journal":{"name":"Integrative physiological and behavioral science : the official journal of the Pavlovian Society","volume":" ","pages":"318-33"},"PeriodicalIF":0.0,"publicationDate":"2004-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02734170","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25694832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13