Implementation science communications最新文献

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Correction: Matters arising: a commentary on "Failing to succeed: advancing mechanistic understanding of implementation strategies through retrospective and prospective use of causal pathway diagrams" by Austad et al. 2025. 更正:出现的问题:奥斯塔德等人在2025年对“未能成功:通过回顾性和前瞻性使用因果路径图来推进对实施策略的机制理解”的评论。
IF 3.5
Implementation science communications Pub Date : 2026-06-23 DOI: 10.1186/s43058-026-01018-6
Bo Kim, Cara C Lewis
{"title":"Correction: Matters arising: a commentary on \"Failing to succeed: advancing mechanistic understanding of implementation strategies through retrospective and prospective use of causal pathway diagrams\" by Austad et al. 2025.","authors":"Bo Kim, Cara C Lewis","doi":"10.1186/s43058-026-01018-6","DOIUrl":"10.1186/s43058-026-01018-6","url":null,"abstract":"","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":"7 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13289425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The PIECES multi-site comparative case study protocol: mixed methods implementation evaluation of adapting, implementing and tailoring primary cancer prevention programmes in diverse contexts. PIECES多站点比较案例研究方案:在不同背景下调整、实施和定制初级癌症预防规划的混合方法实施评估。
IF 3.5
Implementation science communications Pub Date : 2026-06-23 DOI: 10.1186/s43058-026-01002-0
Nikita Hensen, Rixt A Smit, Anna Barrero, Jasmijn Breunese, Genc Burazeri, Saverio Caini, Esteve Fernández, Giuseppe Gorini, Lena Grams, Clara Garcia Mercader, Bethany Hipple Walters, Hanne Karolina Hinderaker, Monika Janda, Alba Jiménez-Rueda, Jassia Iqbal Jaffery, Julia Kahlhöfer, Robin Maria Francisca Kenter, Pauline Lödding, Lisa Macaulay, Kateryna Marushko, Marina Ramiro-Pareta, Rachel O'Donnell, Victoria Porthe, Caridad Pontes, Jordi Piera-Jiménez, Gentiana Qirjako, Padraic Rocliffe, Sean Semple, Sigrid A Troelstra, Hidde P van der Ploeg, Marc C Willemsen, Catherine Woods, Alban Ylli, Christiaan Vis, Cristina Martínez, Femke van Nassau
{"title":"The PIECES multi-site comparative case study protocol: mixed methods implementation evaluation of adapting, implementing and tailoring primary cancer prevention programmes in diverse contexts.","authors":"Nikita Hensen, Rixt A Smit, Anna Barrero, Jasmijn Breunese, Genc Burazeri, Saverio Caini, Esteve Fernández, Giuseppe Gorini, Lena Grams, Clara Garcia Mercader, Bethany Hipple Walters, Hanne Karolina Hinderaker, Monika Janda, Alba Jiménez-Rueda, Jassia Iqbal Jaffery, Julia Kahlhöfer, Robin Maria Francisca Kenter, Pauline Lödding, Lisa Macaulay, Kateryna Marushko, Marina Ramiro-Pareta, Rachel O'Donnell, Victoria Porthe, Caridad Pontes, Jordi Piera-Jiménez, Gentiana Qirjako, Padraic Rocliffe, Sean Semple, Sigrid A Troelstra, Hidde P van der Ploeg, Marc C Willemsen, Catherine Woods, Alban Ylli, Christiaan Vis, Cristina Martínez, Femke van Nassau","doi":"10.1186/s43058-026-01002-0","DOIUrl":"10.1186/s43058-026-01002-0","url":null,"abstract":"<p><strong>Background: </strong>Effective implementation of evidence-based programmes in real-world settings requires the capacity to adapt programmes and tailor implementation strategies to local contexts. Many primary cancer prevention (PCP) programmes that are effective in controlled settings struggle in routine practice. Although several frameworks outline principles of adaptation and tailoring, practical guidance on how to operationalise these processes remains limited. The PIECES project aims to help address this gap by developing, implementing, and evaluating structured support for tailored implementation of PCP programmes. Within the PIECES project, a toolkit was co-developed with practitioners and researchers to provide theory- and evidence-informed guidance for adapting, tailoring, implementing, and evaluating PCP programmes. The toolkit aims to strengthen implementation competencies through structured planning, collaborative learning, and evidence-informed decision-making. This paper presents the protocol for the PIECES study which evaluates the toolkit's usability, feasibility, and mechanisms of impact of PCP programmes across diverse healthcare and community settings.</p><p><strong>Methods: </strong>The PIECES study uses a multi-site pre-post comparative case study design with a mixed-methods implementation evaluation across 11 sites in Europe and Australia, reflecting variation in organisational structures, resources, and cultural contexts. The primary outcome is change in implementation competencies among toolkit users. Guided by the UK MRC Process Evaluation Framework and Proctor's implementation outcomes, the process evaluation examines toolkit usability, feasibility, user satisfaction, and perceived impact on implementation processes and outcomes. Quantitative and qualitative data, toolkit log data, and structured field notes will be collected at six-month intervals (2025-2027). In parallel, a realist evaluation will explore how, why, and under what conditions the toolkit supports tailored implementation. Together, these approaches provide complementary descriptive and explanatory insights into the mechanisms and contextual factors shaping tailored implementation of PCP programmes.</p><p><strong>Discussion: </strong>This study is expected to contribute to implementation science by evaluating a structured, evidence-informed tool designed to strengthen capacity for tailored implementation of PCP programmes. Its multi-country design offers a natural field-laboratory to explore how implementation support tools function across varying contexts. By integrating process and realist evaluation approaches, the study is designed to generate practical and theoretical evidence to inform scalable, context-sensitive strategies and enhance the sustainability and impact of evidence-based prevention efforts.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov ID NCT06718322.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing the collaborative chronic care model for mental health: a nonrandomized clinical trial. 实施精神卫生协作慢性护理模式:一项非随机临床试验。
IF 3.5
Implementation science communications Pub Date : 2026-06-22 DOI: 10.1186/s43058-026-00995-y
Christopher J Miller, Jennifer L Sullivan, Kelly Stolzmann, Rebecca A Raciborski, Madisen Brown, Hannah M Bailey, Samantha L Connolly, Alexandra L Morena, Maura Dougherty, Alexandria Henderson, Andrea Rehmert, Lauren M Sippel, Bo Kim
{"title":"Implementing the collaborative chronic care model for mental health: a nonrandomized clinical trial.","authors":"Christopher J Miller, Jennifer L Sullivan, Kelly Stolzmann, Rebecca A Raciborski, Madisen Brown, Hannah M Bailey, Samantha L Connolly, Alexandra L Morena, Maura Dougherty, Alexandria Henderson, Andrea Rehmert, Lauren M Sippel, Bo Kim","doi":"10.1186/s43058-026-00995-y","DOIUrl":"10.1186/s43058-026-00995-y","url":null,"abstract":"<p><strong>Background: </strong>Collaborative chronic care models (CCMs) are an evidence-based way to structure care in outpatient mental health settings. This project investigated whether implementation facilitation (IF) can enhance CCM-consistent outpatient mental health care and reduce mental health hospitalizations compared with centralized technical assistance (CTA).</p><p><strong>Methods: </strong>This was a stepped wedge hybrid 2 implementation-effectiveness trial in outpatient mental health clinics at eight US Department of Veterans Affairs (VA) medical centers (four waves, two sites each) conducted from 2022 to 2024. Staff participants included clinicians involved in delivering team-based outpatient mental health care. The patient sample consisted of US military veterans treated by 42 participating mental health teams. IF was used for 8-9 months to increase alignment with CCM principles at each participating site. All the sites (including eight comparison sites that were nonrandomized but matched on key variables) had access to CTA. The coprimary outcomes were (a) alignment with CCM-based care evaluated using the Role Clarity and Team Primacy subscales of the Team Development Measure [TDM], and (b) mental health hospitalizations extracted from the electronic health record during the year following initiation of IF.</p><p><strong>Results: </strong>The sample included n = 20,835 patients at participating sites and n = 60,221 patients at comparison sites. The pre-implementation TDM was completed by 134 staff members, and post-implementation TDM was completed by 109 staff members. Role Clarity and Team Primacy subscales of the TDM demonstrated small, nonstatistically significant improvement after completing IF (p = 0.33[t-value: 0.97] and 0.14 [t-value: 1.48], respectively). Multivariate generalized linear mixed models indicated participating sites had similar mental health hospitalization rates following IF initiation compared to sites receiving CTA alone.</p><p><strong>Conclusion: </strong>This trial revealed that IF to enhance CCM-consistent clinical practices in outpatient mental health teams was associated with small improvements in team functioning that did not achieve statistical significance. Mental health hospitalization rates did not differ for sites using IF versus CTA. TDM-based assessments of team functioning at baseline were similar to post-implementation results from a prior trial, suggesting that CTA to support team-based care may have increased team functioning in these settings prior to trial initiation.</p><p><strong>Trial registration: </strong>NCT05997836. Retrospectively registered 18 August 2023: https://clinicaltrials.gov/study/NCT05997836?term=NCT05997836%26rank=1 . Ethical approval: This evaluation was conducted as a quality improvement activity for VA and was deemed by the R&D Committee at the VA Boston Healthcare System not to be research; therefore, it was not subject to IRB review.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148304153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing an adapted patient safety bundle for pregnancy-related severe hypertension to improve recognition, response, and respectful care in the outpatient setting. 实施适合妊娠相关的严重高血压患者安全束,以提高在门诊环境的认识,反应和尊重护理。
IF 3.5
Implementation science communications Pub Date : 2026-06-22 DOI: 10.1186/s43058-026-01012-y
E Nicole Teal, Narges Farahi, Jennifer Leeman, Feng-Chang Lin, Kimberly Harper, Alexandra F Lightfoot, M Kathryn Menard
{"title":"Implementing an adapted patient safety bundle for pregnancy-related severe hypertension to improve recognition, response, and respectful care in the outpatient setting.","authors":"E Nicole Teal, Narges Farahi, Jennifer Leeman, Feng-Chang Lin, Kimberly Harper, Alexandra F Lightfoot, M Kathryn Menard","doi":"10.1186/s43058-026-01012-y","DOIUrl":"10.1186/s43058-026-01012-y","url":null,"abstract":"<p><strong>Background: </strong>Severe hypertension (HTN) during pregnancy is highly associated with adverse perinatal outcomes, yet many cases occur in outpatient settings where standardized management is lacking. We used a community-engaged approach to adapt an evidence-based inpatient HTN bundle for outpatient care, creating the Outpatient HTN (O-HTN) Bundle. This study aimed to evaluate the feasibility, acceptability, and impact of three implementation strategies (1) identifying and preparing champions, (2) providing ongoing training, and (3) simulation.</p><p><strong>Methods: </strong>We conducted a pre-post pilot study in three Federally Qualified Health Centers (FQHCs) from 9/2021-6/2022. Multidisciplinary clinical teams comprised of a medical assistant, nurse, provider (midwife or physician), and pharmacy staff received training on the O-HTN Bundle and participated in pre- and post-training simulations. Simulations involved a patient actor presenting with severe HTN during a prenatal visit. Trained observers used a checklist to evaluate clinical team fidelity to the O-HTN Bundle algorithm. Observers, clinical team members, and the patient actor assessed provision of respectful care via a Respectful Care Reflection Tool. The primary outcome was fidelity to the O-HTN Bundle; secondary outcomes included respectful care and feasibility and acceptability of the implementation strategies. Feasibility was defined by engagement in trainings/simulations. Acceptability was assessed with a study-specific survey. Paired t-tests compared fidelity and respectful care scores pre- and post-training. Descriptive statistics summarized acceptability and feasibility data.</p><p><strong>Results: </strong>The implementation strategies were feasible; 19 clinical teams participated, representing 59% of all prenatal providers across the three FQHCs. All 19 teams participated in the O-HTN Bundle training and pre- and post-training simulations. The strategies were also effective: mean fidelity scores improved from 78% pre-training to 95% post-training (p = 0.006). Significant gains were made on severe HTN identification, treatment, and escalation to higher level of care. Respectful care scores also improved, though not significantly. Survey results indicated acceptability of the training and simulation model.</p><p><strong>Conclusion: </strong>In this pilot study, clinic champions, training, and simulation were feasible, acceptable, and effective strategies to improve fidelity to the O-HTN Bundle and thus response to severe HTN in pregnancy. These findings support broader implementation of the O-HTN Bundle.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148304138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bayesian adaptive designs for the optimisation of implementation strategies: a virtual re-execution of the Physically Active Children in Education (PACE) trials. 优化实施策略的贝叶斯自适应设计:教育中身体活跃儿童(PACE)试验的虚拟重新执行。
IF 3.5
Implementation science communications Pub Date : 2026-06-22 DOI: 10.1186/s43058-026-01000-2
Erin Nolan, Elizabeth Holliday, Christopher Oldmeadow, Alix Hall, Lucy Leigh, Nicole Nathan, Daniel Barker
{"title":"Bayesian adaptive designs for the optimisation of implementation strategies: a virtual re-execution of the Physically Active Children in Education (PACE) trials.","authors":"Erin Nolan, Elizabeth Holliday, Christopher Oldmeadow, Alix Hall, Lucy Leigh, Nicole Nathan, Daniel Barker","doi":"10.1186/s43058-026-01000-2","DOIUrl":"10.1186/s43058-026-01000-2","url":null,"abstract":"<p><strong>Background: </strong>Current designs used to optimise implementation strategies (e.g., sequential cluster randomised controlled trials (cRCTs) and multi-arm cRCTs) are inefficient and resource intensive. Bayesian adaptive designs may offer a more efficient alternative.</p><p><strong>Methods: </strong>We conducted a virtual trial re-execution to assess the impact of using a Bayesian adaptive design for optimising an existing implementation strategy (Physically Active Children in education (PACE)) used to support the delivery of school-based physical activity. The two previous, sequential, two-arm cRCTs used to optimise PACE were combined into a single three-arm cRCT. We assessed the performance of a fixed version of this trial design compared to an adaptive version incorporating one, two, or three interim analyses in a virtual re-execution. Adaptions included arm dropping and early stopping for futility, noninferiority, or efficacy.</p><p><strong>Results: </strong>All adaptive designs stopped early for noninferiority, declaring the lower cost treatment as the optimal arm at interim analysis one. This was the same conclusion obtained in the fixed version of the three-arm cRCT and the original sequential two-arm cRCTs. Using adaptive designs, the same conclusion was reached using 50-75% fewer clusters. The adaptive trials would have taken approximately 40% less time than the sequential two-arm cRCTs, not accounting for the time to analyse the interim analysis. However, the treatment effect was biased towards the lower cost treatment, and this bias (away from the full-sample posterior estimate) increased when fewer clusters were randomised. The first 18 schools randomised were Catholic schools, and they responded better to the lower cost treatment compared to government schools. When the distribution of school type was balanced at each interim (i.e. matched the final sample proportions) the bias towards the lower cost treatment was reduced.</p><p><strong>Conclusions: </strong>Bayesian adaptive designs offer improved efficiency for trials aiming to optimise implementation strategies, reducing the time and sample size needed to find the optimal strategy. However, care is required to ensure confounding demographics are balanced at each interim analysis to reduce the risk of making a type 1 or 2 error or an incorrect adaptive design decision (e.g. dropping an effective arm, incorrectly stopping early).</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148304164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What influenced the use of embedded genetic expertise by non-genetic clinicians: a qualitative study using the diffusion of innovations theory and theoretical domains framework. 是什么影响了非遗传临床医生使用嵌入式遗传专业知识:一项使用创新理论和理论领域框架扩散的定性研究。
IF 3.5
Implementation science communications Pub Date : 2026-06-22 DOI: 10.1186/s43058-026-01026-6
Trang Thu Do, Belinda Dawson McClaren, Clara Gaff, Melissa Martyn
{"title":"What influenced the use of embedded genetic expertise by non-genetic clinicians: a qualitative study using the diffusion of innovations theory and theoretical domains framework.","authors":"Trang Thu Do, Belinda Dawson McClaren, Clara Gaff, Melissa Martyn","doi":"10.1186/s43058-026-01026-6","DOIUrl":"10.1186/s43058-026-01026-6","url":null,"abstract":"<p><strong>Background: </strong>While employing change agents is a widely used strategy to support implementation of evidence-based practices in healthcare, the perspectives of the target users of this intervention are under-explored. Within a genomic care setting in Australia, we examined non-genetic clinicians' views of and experience with embedded genetic counsellors employed as external change agents to support the adoption of genomics in clinical care.</p><p><strong>Methods: </strong>We conducted qualitative interviews with 16 non-genetic healthcare professionals involved in different models of genomic care, all of which employed genetic counsellors as external change agents to provide embedded genetic expertise and support in non-genetic specialty clinics. The Diffusion of Innovations (DOI) theory and the Theoretical Domains Framework (TDF) were drawn upon to guide the study design and data analysis to explore the enablers/barriers to non-genetic clinicians' use of genetic expertise and the wider implementation context of the change agent approach.</p><p><strong>Results: </strong>The TDF domain 'Belief about Consequences' was a positive influence on non-genetic specialists' view of the embedded change agents, when they believed that the change agents positively impacted patient outcomes and the clinicians' knowledge and practice of using genomics in routine care. Meanwhile, major barriers were related to 'Environmental Context & Resources,' e.g. time constraints and logistic hurdles of involving change agents. Perceived attributes related to 'complexity' and 'observability' of genetic expertise were critical factors influencing the decision to put the support to actual use, impacting the diffusion of the genomic innovation.</p><p><strong>Conclusions: </strong>Our study offers insights into behavioural influences and contextual conditions shaping clinicians' decisions to interact with genetic counsellor change agents and incorporate (or not) their expertise into their routine care. Such understandings can inform future design and implementation of interventions that use change agents to support the adoption of innovations, such as genomics, effectively and sustainably.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13543347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148304212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delivering effective non-invasive ventilation in amyotrophic lateral sclerosis using intensive remote support (DENIM): protocol for an embedded process evaluation in a hybrid type 3 implementation-effectiveness trial. 使用密集远程支持(DENIM)为肌萎缩性侧索硬化症患者提供有效的无创通气:一项混合3型实施-有效性试验的嵌入式过程评估方案。
IF 3.5
Implementation science communications Pub Date : 2026-06-20 DOI: 10.1186/s43058-026-01023-9
Carla Girling, Gemma Ryan, Mike Bradburn, Thais Caprioli, Shoba Dawson, Emily Fisher, Noa Haynes, Esther Herbert, Harry Hill, Daniel Hind, Carl May, Stephen Bianchi, Matthew Cox, Georgios Kaltsakas, Charlotte Massey, Emily Mayberry, Ben Messer, David Needham, Rebecca Playle, Christopher McDermott, Alys Wyn Griffiths, Esther Hobson
{"title":"Delivering effective non-invasive ventilation in amyotrophic lateral sclerosis using intensive remote support (DENIM): protocol for an embedded process evaluation in a hybrid type 3 implementation-effectiveness trial.","authors":"Carla Girling, Gemma Ryan, Mike Bradburn, Thais Caprioli, Shoba Dawson, Emily Fisher, Noa Haynes, Esther Herbert, Harry Hill, Daniel Hind, Carl May, Stephen Bianchi, Matthew Cox, Georgios Kaltsakas, Charlotte Massey, Emily Mayberry, Ben Messer, David Needham, Rebecca Playle, Christopher McDermott, Alys Wyn Griffiths, Esther Hobson","doi":"10.1186/s43058-026-01023-9","DOIUrl":"10.1186/s43058-026-01023-9","url":null,"abstract":"<p><strong>Background: </strong>Non-invasive ventilation (NIV) is the only intervention that significantly improves survival and quality of life in motor neuron disease, extending life by 8-13 months. However, at least half of patients are unable to reach the recommended ≥ 4 h daily NIV use, and current NHS services provide insufficient follow-up for intensive optimisation. Delivering Effective Non-Invasive ventilation in Motor neuron disease using intensive remote support (DENIM) is a stepped-wedge cluster randomised trial. This protocol describes a process evaluation embedded within DENIM aiming to understand how and why the implementation strategy works (or does not work) across different contexts.</p><p><strong>Method: </strong>The process evaluation employs a convergent mixed-methods multiple-case study design across twelve NHS ventilation services. We developed a programme theory informed by Normalization Process Theory (NPT), the Consolidated Framework for Implementation Research and Expert Recommendations for Implementing Change, which states how the DENIM implementation strategy is expected to achieve normalisation of evidence-based NIV practice. Data collection across twelve sites include: ethnographic observations of patient-staff interactions; semi-structured interviews with staff (n = 24-48) and patients/carers (n = 24) exploring implementation experiences; the NoMAD questionnaire measuring normalisation perceptions from healthcare professionals within the services and NIV adherence data from participants' ventilators. Barriers and facilitators to research participation for underserved populations including ethnic minorities, those with low digital literacy, and women over 80 with bulbar onset disease will also be identified. Qualitative data will be analysed using NPT-informed thematic analysis. Integration occurs at three levels (design, methods, interpretation) with joint display tables presenting quantitative and qualitative findings alongside meta-inferences.</p><p><strong>Discussion: </strong>This process evaluation will generate explanatory insights into how implementation strategies can address the evidence-to-practice gap in complex, technology-supported care for progressive diseases, with implications for health equity and wider NHS digital transformation.</p><p><strong>Trial registration: </strong>ISRCTN10105285. 16/04/2025.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Tracing the threads: a system dynamics and network diffusion model of kangaroo care implementation in neonatal care. 更正:追踪线索:袋鼠式护理在新生儿护理中实施的系统动力学和网络扩散模型。
IF 3.5
Implementation science communications Pub Date : 2026-06-19 DOI: 10.1186/s43058-026-01017-7
Emanuela Nyantakyi, Per Block, Lauren Clack, Marie-Therese Schultes
{"title":"Correction: Tracing the threads: a system dynamics and network diffusion model of kangaroo care implementation in neonatal care.","authors":"Emanuela Nyantakyi, Per Block, Lauren Clack, Marie-Therese Schultes","doi":"10.1186/s43058-026-01017-7","DOIUrl":"10.1186/s43058-026-01017-7","url":null,"abstract":"","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":"7 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13281572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factor selection in configurational comparative analysis - guidance for implementation researchers. 构型比较分析中的因素选择——对实施研究人员的指导。
IF 3.5
Implementation science communications Pub Date : 2026-06-19 DOI: 10.1186/s43058-026-00981-4
Laura Caci, Kathrin Blum, Lauren Clack, Bianca Albers
{"title":"Factor selection in configurational comparative analysis - guidance for implementation researchers.","authors":"Laura Caci, Kathrin Blum, Lauren Clack, Bianca Albers","doi":"10.1186/s43058-026-00981-4","DOIUrl":"10.1186/s43058-026-00981-4","url":null,"abstract":"<p><strong>Background: </strong>Configurational comparative methods (CCMs) are designed for the systematic comparison of case data to identify necessary and sufficient conditions for an outcome. The complex interplay of contextual factors, implementation strategies, and intervention components makes CCMs particularly suitable for implementation studies. Factor selection is a stage in CCMs during which researchers determine a limited set of variables of interest for analysis. Guidance that helps implementation researchers to select a manageable set of factors from a plethora of potentially interesting components is warranted but lacking, especially, for pre-data collection. We provide such guidance with an emphasis on (1) intentional data collection, and (2) broad engagement of interest-holders across different stages of factor selection.</p><p><strong>Methods: </strong>Our suggested approach consists of four stages: (1) factor identification, (2) factor prioritization, (3) factor determination, and (4) factor operationalization. Throughout these stages, we highlight opportunities for engaging interest-holders.</p><p><strong>Results: </strong>We illustrate all stages using experience from a multinational hybrid implementation-effectiveness trial in the field of infection prevention. First, we conducted a systematic review to identify potentially relevant factors. Second, we applied the Nominal Group Technique in meetings with interest-holders to prioritize previously identified factors. Third, we conducted two project workshops to decide on a final set of factors. Fourth, we operationalized factors into measurable units and assessed them using qualitative and quantitative methods.</p><p><strong>Conclusions: </strong>We present a methodology and applied case example for pre-data collection factor selection for CCMs. The proposed method comprises four stages, each requiring implementation researchers to balance scientific rigor with pragmatism, while ensuring meaningful engagement of interest-holders. This guidance closes a gap in existing recommendations, which have primarily focused on factor selection during data analysis. Making CCMs more accessible and increasing their use should remain a central priority in implementation science.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A scoping review of obesity policies and reimbursement landscape: global insights and lessons for Thailand. 对肥胖政策和报销情况的范围审查:泰国的全球见解和教训。
IF 3.5
Implementation science communications Pub Date : 2026-06-19 DOI: 10.1186/s43058-026-00985-0
Petch Rawdaree, Nisita Jirawutkornkul, Parnnaphat Luksameesate, Dilok Piyayotai
{"title":"A scoping review of obesity policies and reimbursement landscape: global insights and lessons for Thailand.","authors":"Petch Rawdaree, Nisita Jirawutkornkul, Parnnaphat Luksameesate, Dilok Piyayotai","doi":"10.1186/s43058-026-00985-0","DOIUrl":"10.1186/s43058-026-00985-0","url":null,"abstract":"<p><strong>Background: </strong>Obesity is one of the world's leading health burdens. The prevalence of overweight and obesity continues to rise globally, creating significant healthcare and socioeconomic challenges. Effective strategies are essential to address this crisis.</p><p><strong>Objective: </strong>To thematically map global obesity management strategies and policies, focusing on policy- and system-level features relevant to national implementation, to inform context-sensitive policy considerations in Thailand and similar health systems.</p><p><strong>Methods: </strong>A scoping review was conducted to map global obesity management policies and identify key themes, challenges, success factors, and future directions. Electronic databases, including PubMed, EMBASE, and Scopus, were searched for relevant documents published between January 1, 2004, and June 30, 2024. The gray literature was also reviewed to assess the reimbursement status of obesity medications.</p><p><strong>Results: </strong>The analysis identified three main policy domains: public policy, food security and healthy environments, and healthcare system support. Through the scoping review and thematic synthesis, 19 distinct policy themes were identified. High-income countries generally demonstrated more comprehensive and integrated strategies compared to middle-income countries. Regarding medical reimbursement for obesity treatment, coverage for bariatric surgery was more commonly available across settings, whereas reimbursement for anti-obesity medications remained limited. For example, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were reimbursed for obesity indications in selected high-income countries, including Denmark and the United Kingdom. In contrast, in countries such as the United States, China, and Thailand (restricted to the Civil Servant Medical Benefit Scheme), these agents were reimbursed primarily for type 2 diabetes rather than for weight management.</p><p><strong>Conclusions: </strong>Integrated strategies that combine prevention and treatment, supported by interagency collaboration, are critical for effective obesity management. Additionally, designing policies that align with the social, cultural, and economic context of each country is crucial for achieving sustainable obesity management.</p>","PeriodicalId":73355,"journal":{"name":"Implementation science communications","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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