Gut microbiome (Cambridge, England)最新文献_第2页

Regular consumption of lacto-fermented vegetables has greater effects on the gut metabolome compared with the microbiome. 与微生物组相比，经常食用乳酸发酵蔬菜对肠道代谢组的影响更大

Gut microbiome (Cambridge, England) Pub Date : 2023-06-29 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.9

Kylene Guse, Ashok Sharma, Emily Weyenberg, Sam Davison, Yiwei Ma, Yuni Choi, Abigail J Johnson, Chi Chen, Andres Gomez

{"title":"Regular consumption of lacto-fermented vegetables has greater effects on the gut metabolome compared with the microbiome.","authors":"Kylene Guse, Ashok Sharma, Emily Weyenberg, Sam Davison, Yiwei Ma, Yuni Choi, Abigail J Johnson, Chi Chen, Andres Gomez","doi":"10.1017/gmb.2023.9","DOIUrl":"10.1017/gmb.2023.9","url":null,"abstract":"The industrialisation of Western food systems has reduced the regular consumption of lacto-fermented vegetables (LFV). Consuming LFV may exert health benefits through the alteration of the gut microbiome, but the mechanisms involved remain unclear. To start understanding the possible benefits of LFV, we compared faecal microbial diversity and composition, as well as dietary habits between individuals who regularly consume LFV (n = 23) and those who do not (n = 24). We utilised microbial DNA amplicon sequencing (16S rRNA and ITS2) and untargeted metabolomics (LC-MS) to analyse stool samples. Study participants also provided three consecutive days of dietary data. Results show minor effects on microbiome composition; with the enrichment of a few microorganisms potentially associated with vegetable ferments, such as Leuconostoc mesenteroides and Rhodotorula mucilaginosa (P < 0.05), in LFV consumers. However, LFV consumption had greater effects on the faecal metabolome, with higher abundances of butyrate, acetate, and valerate (P < 0.05) and significantly greater metabolome diversity (P < 0.001). Overall, the observations of minor changes in the faecal microbiome and greater effects on the faecal metabolome from LFV consumption warrant further investigations on the health significance of LFV as regular components of the daily diet in humans.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e11"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49226842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The intestinal microbiota as an ally in the treatment of Alzheimer's disease. 肠道菌群在治疗阿尔茨海默病中的作用

Gut microbiome (Cambridge, England) Pub Date : 2023-06-19 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.8

Sabrina Sehn Hilgert, Daniel Penteado Martins Dias

{"title":"The intestinal microbiota as an ally in the treatment of Alzheimer's disease.","authors":"Sabrina Sehn Hilgert, Daniel Penteado Martins Dias","doi":"10.1017/gmb.2023.8","DOIUrl":"10.1017/gmb.2023.8","url":null,"abstract":"The evolution of the understanding of the intestinal microbiota and its influence on our organism leverages it as a potential protagonist in therapies aimed at diseases that affect not only the intestine but also neural pathways and the central nervous system itself. This study, developed from a thorough systematic review, sought to demonstrate the influence of the intervention on the intestinal microbiota in subjects with Alzheimer's disease. Clinical trials using different classes of probiotics have depicted noteworthy remission of symptoms, whose measurement was performed based on screenings and scores applied before, during, and after the period of probiotics use, allowing the observation of changes in functionality and symptomatology of patients. On the other hand, faecal microbiota transplantation requires further validation through clinical trials, even though it has already been reported in case studies as promising from the symptomatology point of view. The current compilation of studies made it possible to demonstrate the potential influence of the intestinal microbiota on Alzheimer's pathology. However, new clinical studies with a larger number of participants are needed to obtain further clarification on pathophysiological correlations.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e9"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48841928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The gut microbiota-neuroimmune crosstalk and neuropathic pain: a scoping review. 肠道微生物群-神经免疫串扰和神经性疼痛:范围综述

Gut microbiome (Cambridge, England) Pub Date : 2023-06-19 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.7

Gayani Nawarathna, Kausar S Fakhruddin, Ali I S A Shorbagi, Lakshman P Samaranayake

{"title":"The gut microbiota-neuroimmune crosstalk and neuropathic pain: a scoping review.","authors":"Gayani Nawarathna, Kausar S Fakhruddin, Ali I S A Shorbagi, Lakshman P Samaranayake","doi":"10.1017/gmb.2023.7","DOIUrl":"10.1017/gmb.2023.7","url":null,"abstract":"Environmental stressors can disrupt the gut-brain relationship and alter the gut microbial composition, potentially leading to chronic pain, including neuropathic pain (NP). To understand this complex relationship, we conducted a systematic scoping review to examine the gut microbial-neuroimmune connection to NP and the potential therapeutic targets. The review includes English-language manuscripts in databases such as MEDLINE, Cochrane, and DOAJ between January 2000 and April 2022. Out of the 48 full texts examined, only 15 articles met the inclusion criteria. These included a randomised controlled trial involving 327 individuals, an in vitro, and 13 animal model studies. The findings suggest that the gut flora plays a role in the immunological, neurological, and metabolic signalling pathways associated with NP. Animal studies have been the primary focus in this area, indicating that an imbalanced-gut microbiome and subsequent activation of biochemical and neuro-immunologic pathways may influence the development of NP. This review provides a comprehensive summary of the gut microbiome-immune-NP axis and identifies potential therapeutic targets. However, since most of the evidence comes from animal studies, future research should include clinical trials to gain a better understanding of the role of gut microbiota in NP and discover new therapeutic strategies.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48871637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modulation of gut microbiota by diet and probiotics: potential approaches to prevent gestational diabetes mellitus. 饮食和益生菌对肠道微生物群的调节：预防妊娠期糖尿病的潜在途径

Gut microbiome (Cambridge, England) Pub Date : 2023-06-13 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.6

Marisa Carreira Cruz, Sarah Azinheiro, Sónia Gonçalves Pereira

{"title":"Modulation of gut microbiota by diet and probiotics: potential approaches to prevent gestational diabetes mellitus.","authors":"Marisa Carreira Cruz, Sarah Azinheiro, Sónia Gonçalves Pereira","doi":"10.1017/gmb.2023.6","DOIUrl":"10.1017/gmb.2023.6","url":null,"abstract":"Gestational diabetes mellitus (GDM) is a rising global health problem that affects approximately 6% of pregnant women. Lifestyle interventions, particularly diet, and exercise are the first-line treatment, followed by pharmacotherapy, but with associated side effects to both mother and offspring. Modulation of gut microbiota may help prevent or manage GDM. Some gut bacterial groups associated with GDM are also associated with inflammatory biomarkers and gut dysbiosis. Available literature reports that low-glycaemic index diet reduces maternal fasting and 2-hour postprandial glucose and maintains a beneficial gut bacterial composition. Pre- and probiotics can aid GDM therapy by modulating gut microbiota to eubiotic status and improving glucose metabolism. Probiotics as adjuvant GDM therapy should consider bacterial strains, dosage, and treatment duration. Limitations in their use require further studies to develop specific probiotic-based GDM supplement therapy that impacts glycaemic control and inflammatory status by reducing fasting plasma glucose, insulin resistance, and improving lipid profiles of pregnant women.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e17"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47641360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

White kidney bean extract as a nutraceutical: effects on gut microbiota, alpha-amylase inhibition, and user experiences. 白芸豆提取物作为营养品：对肠道微生物群、α-淀粉酶抑制和用户体验的影响

Gut microbiome (Cambridge, England) Pub Date : 2023-06-01 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.5

David Houghton, Oliver M Shannon, Peter I Chater, Matthew D Wilcox, Jeffrey P Pearson, Kyle Stanforth, Cara Jordan, Leah Avery, Alasdair P Blain, Abraham Joel, Ruth Jeffers, Ruth Nolan, Andrew Nelson, Christopher J Stewart, Fiona C Malcomson

{"title":"White kidney bean extract as a nutraceutical: effects on gut microbiota, alpha-amylase inhibition, and user experiences.","authors":"David Houghton, Oliver M Shannon, Peter I Chater, Matthew D Wilcox, Jeffrey P Pearson, Kyle Stanforth, Cara Jordan, Leah Avery, Alasdair P Blain, Abraham Joel, Ruth Jeffers, Ruth Nolan, Andrew Nelson, Christopher J Stewart, Fiona C Malcomson","doi":"10.1017/gmb.2023.5","DOIUrl":"10.1017/gmb.2023.5","url":null,"abstract":"White kidney bean extract (WKBE) is a nutraceutical often advocated as an anti-obesity agent. The main proposed mechanism for these effects is alpha-amylase inhibition, thereby slowing carbohydrate digestion and absorption. Thus, it is possible that WKBE could impact the gut microbiota and modulate gut health. We investigated the effects of supplementing 20 healthy adults with WKBE for 1 week in a randomised, placebo-controlled crossover trial on the composition of the gut microbiota, gastrointestinal (GI) inflammation (faecal calprotectin), GI symptoms, and stool habits. We conducted in vitro experiments and used a gut model system to explore potential inhibition of alpha-amylase. We gained qualitative insight into participant experiences of using WKBE via focus groups. WKBE supplementation decreased the relative abundance of Bacteroidetes and increased that of Firmicutes, however, there were no significant differences in post-intervention gut microbiota measurements between the WKBE and control. There were no significant effects on GI inflammation or symptoms related to constipation, or stool consistency or frequency. Our in vitro and gut model system analyses showed no effects of WKBE on alpha-amylase activity. Our findings suggest that WKBE may modulate the gut microbiota in healthy adults, however, the underlying mechanism is unlikely due to active site inhibition of alpha-amylase.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e8"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49657845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbial gut dysbiosis induced by xenobiotics in model organisms and the relevance of experimental criteria: a minireview. 模式生物中由异种生物诱导的微生物肠道失调和实验标准的相关性:综述

Gut microbiome (Cambridge, England) Pub Date : 2023-04-11 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.3

Beatriz Ibarra-Mendoza, Bruno Gomez-Gil, Miguel Betancourt-Lozano, Luciana Raggi, Beatriz Yáñez-Rivera

{"title":"Microbial gut dysbiosis induced by xenobiotics in model organisms and the relevance of experimental criteria: a minireview.","authors":"Beatriz Ibarra-Mendoza, Bruno Gomez-Gil, Miguel Betancourt-Lozano, Luciana Raggi, Beatriz Yáñez-Rivera","doi":"10.1017/gmb.2023.3","DOIUrl":"10.1017/gmb.2023.3","url":null,"abstract":"The gut microbiota is a dynamic ecosystem involved in multiple physiological processes that affect host health. Several factors affect intestinal microbial communities including dietary exposure to xenobiotics, which is highly concerning due to their widespread distribution. Current knowledge of this topic comes from culture-dependent methods, 16S rRNA amplicon fingerprinting, and metagenomics, but a standardised procedures framework remains lacking. This minireview integrates 45 studies from a systematic search using terms related to gut microbiota and its disruption. Only publications encompassing dietary-oral exposure and experimental gut microbiota assessments were included. The results were divided and described according to the biological model used and the disruption observed in the gut microbiota. An overall dysbiotic effect was unclear due to the variety of contaminants and hosts evaluated and the experimental gaps between publications. More standardised experimental designs, including WGS and physiological tests, are needed to establish how a particular xenobiotic can alter the gut microbiota and how the results can be extrapolated.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e7"},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45827195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbiota and probiotics: chances and challenges - a symposium report. 微生物群和益生菌:机遇和挑战-研讨会报告

Gut microbiome (Cambridge, England) Pub Date : 2023-03-27 eCollection Date: 2023-01-01 DOI: 10.1017/gmb.2023.4

Carrie Helen Stevenson Ruxton, Chiyuki Kajita, Paola Rocca, Bruno Pot

{"title":"Microbiota and probiotics: chances and challenges - a symposium report.","authors":"Carrie Helen Stevenson Ruxton, Chiyuki Kajita, Paola Rocca, Bruno Pot","doi":"10.1017/gmb.2023.4","DOIUrl":"10.1017/gmb.2023.4","url":null,"abstract":"The 10th International Yakult Symposium was held in Milan, Italy, on 13-14 October 2022. Two keynote lectures covered the crewed journey to space and its implications for the human microbiome, and how current regulatory systems can be adapted and updated to ensure the safety of microorganisms used as probiotics or food processing ingredients. The remaining lectures were split into sections entitled \"Chances\" and \"Challenges.\" The \"Chances\" section explored opportunities for the science of probiotics and fermented foods to contribute to diverse areas of health such as irritable bowel syndrome, major depression, Parkinson's disease, immune dysfunction, infant colic, intensive care, respiratory infections, and promoting healthy longevity. The \"Challenges\" section included selecting appropriate clinical trial participants and methodologies to minimise heterogeneity in responses, how to view probiotics in the context of One Health, adapting regulatory frameworks, and understanding how substances of bacterial origin can cross the blood-brain barrier. The symposium provided evidence from cutting-edge research that gut eubiosis is vital for human health and, like space, the microbiota deserves further exploration of its vast potential.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":"e6"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11406417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42603753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The gut microbiota is an emerging target for improving brain health during ageing. 肠道微生物群是改善老年期大脑健康的一个新兴目标。

Gut microbiome (Cambridge, England) Pub Date : 2023-01-01 Epub Date: 2022-12-12 DOI: 10.1017/gmb.2022.11

Marcus Boehme, Katherine Elizabeth Guzzetta, Caroline Wasén, Laura Michelle Cox

引用次数: 0

Association of Habitual Intake of Probiotic Supplements and Yogurt with Characteristics of the Gut Microbiome in the Multiethnic Cohort Adiposity Phenotype Study. 多民族肥胖表型研究中益生菌补充剂和酸奶的习惯性摄入与肠道微生物组特征的关系

Gut microbiome (Cambridge, England) Pub Date : 2023-01-01 Epub Date: 2023-07-13 DOI: 10.1017/gmb.2023.10

Weiwen Chai, Gertraud Maskarinec, Unhee Lim, Carol J Boushey, Lynne R Wilkens, V Wendy Setiawan, Loïc Le Marchand, Timothy W Randolph, Isaac C Jenkins, Johanna W Lampe, Meredith A J Hullar

{"title":"Association of Habitual Intake of Probiotic Supplements and Yogurt with Characteristics of the Gut Microbiome in the Multiethnic Cohort Adiposity Phenotype Study.","authors":"Weiwen Chai, Gertraud Maskarinec, Unhee Lim, Carol J Boushey, Lynne R Wilkens, V Wendy Setiawan, Loïc Le Marchand, Timothy W Randolph, Isaac C Jenkins, Johanna W Lampe, Meredith A J Hullar","doi":"10.1017/gmb.2023.10","DOIUrl":"10.1017/gmb.2023.10","url":null,"abstract":"Consumption of probiotics and/or yogurt could be a solution for restoring the balance of the gut microbiota. This study examined associations of regular intake of probiotic supplements or yogurt with the gut microbiota among a diverse population of older adults (N=1,861; 60-72 years). Fecal microbial composition was obtained from 16S rRNA gene sequencing (V1-V3 region). General Linear Models were used to estimate the associations of probiotic supplement or yogurt intake with microbiome measures adjusting for covariates. Compared to non-yogurt consumers (N=1,023), regular yogurt consumers (≥once/week, N=818) had greater Streptococcus (β=0.29, P=0.0003) and lower Odoribacter (β=-0.33, P<0.0001) abundance. The directions of the above associations were consistent across the five ethnic groups but stronger among Japanese Americans (Streptococcus: β=0.56, P=0.0009; Odoribacter: β=-0.62, P=0.0005). Regular intake of probiotic supplements (N=175) was not associated with microbial characteristics (i.e., alpha diversity and the abundance of 152 bacteria genera). Streptococcus is one of the predominant bacteria genera in yogurt products, which may explain the positive association between yogurt consumption and Streptococcus abundance. Our analyses suggest that changes in Odoribacter were independent of changes in Streptococcus abundance. Future studies may investigate whether these microbial genera and their sub-level species mediate potential pathways between yogurt consumption and health.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10927272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45518410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The gut microbiome in children with mood, anxiety, and neurodevelopmental disorders: An umbrella review 患有情绪、焦虑和神经发育障碍儿童的肠道微生物群:综述

Gut microbiome (Cambridge, England) Pub Date : 2023-01-01 DOI: 10.1017/gmb.2023.16

Kaitlin Romano, Ashka N Shah, Anett Schumacher, Clare Zasowski, Tianyi Zhang, Glyneva Bradley-Ridout, Kaitlyn Merriman, John Parkinson, Peter Szatmari, Susan C Campisi, Daphne J Korczak

{"title":"The gut microbiome in children with mood, anxiety, and neurodevelopmental disorders: An umbrella review","authors":"Kaitlin Romano, Ashka N Shah, Anett Schumacher, Clare Zasowski, Tianyi Zhang, Glyneva Bradley-Ridout, Kaitlyn Merriman, John Parkinson, Peter Szatmari, Susan C Campisi, Daphne J Korczak","doi":"10.1017/gmb.2023.16","DOIUrl":"https://doi.org/10.1017/gmb.2023.16","url":null,"abstract":"Abstract Research on the gut microbiome and mental health among children and adolescents is growing. This umbrella review provides a high-level overview of current evidence syntheses to amalgamate current research and inform future directions. Searches were conducted across seven databases for peer-reviewed pediatric (<18 years) review literature. Studies reporting gut microbiome composition and/or biotic supplementation on depression, bipolar disorder, anxiety, attention deficit hyperactivity disorder, autism spectrum disorder (ASD), or obsessive-compulsive disorder (OCD) were included. Deduplication and screening took place in Covidence. A sensitivity analysis was conducted to assess the degree of primary study overlap. Among the 39 included review studies, 23 (59%) were observational and 16 (41%) were interventional. Most reviews (92%) focused on ASD. Over half (56%) of the observational and interventional reviews scored low or critically low for methodological quality. A higher abundance of Clostridium clusters and a lower abundance of Bifidobacterium were consistently observed in ASD studies. Biotic supplementation was associated with ASD symptom improvement. Gut microbiome-mental health evidence syntheses in child and youth depression, anxiety, bipolar disorder, and OCD are lacking. Preliminary evidence suggests an association between specific microbiota and ASD symptoms, with some evidence supporting a role for probiotic supplementation ASD therapy.","PeriodicalId":73187,"journal":{"name":"Gut microbiome (Cambridge, England)","volume":"298 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135595975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0