Global health journal (Amsterdam, Netherlands)最新文献

{"title":"Are the coronavirus disease 2019 (COVID-19)-themed applications launched during the pandemic sustainable?","authors":"Fauzi Budi Satria","doi":"10.1016/j.glohj.2022.07.004","DOIUrl":"10.1016/j.glohj.2022.07.004","url":null,"abstract":"<div><p>Many digital applications (Apps) were launched during the coronavirus disease 2019 (COVID-19) pandemic for various purposes such as information sharing, risk assessment, self-management of symptoms, contact tracing, home monitoring, and decision making. Since the quality of COVID-19-themed Apps varied and was less reliable based on measurements using the mobile Apps rating scale method, some of these Apps are considered useful while some are said to have the potential to harm users. This suggests the need for authorized institutions to validate and ensure the safety and security of these Apps before it was launched in public. This is necessary considering the potential dangers arising from App inaccuracies, as well as the potential misuse of user data due to data breaches. With these considerations in mind, we consider that the vaccine passport is an App with a COVID-19 theme that must be refined and applied sustainably amid the ongoing global crisis and the uncertainty of this pandemic.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 180-182"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40579251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a multifaceted intervention for the improvement of nutritional status and nutrition knowledge of children in poverty-stricken areas in Shaanxi Province, China","authors":"Cai Zhao ,&nbsp;Lu Ma ,&nbsp;Liwang Gao ,&nbsp;Yan Wu ,&nbsp;Yating Yan ,&nbsp;Wen Peng ,&nbsp;Youfa Wang","doi":"10.1016/j.glohj.2022.07.009","DOIUrl":"10.1016/j.glohj.2022.07.009","url":null,"abstract":"<div><h3>Objectives</h3><p>Compare the differences between the intervention and control groups in changes of primary outcomes (body mass index [BMI] and waist-to-height ratio [WHtR]) and secondary outcomes (nutrition knowledge of children and parents), from baseline to the 6- and 12-month follow-ups; examine the associations of changes in nutrition knowledge of children and their parents with children's changes in BMI and WHtR.</p></div><div><h3>Data sources</h3><p>Data collected from four schools in two poverty-stricken counties in northern Shaanxi Province in 2020‒2021.</p></div><div><h3>Methods</h3><p>A multifaced intervention program targeted children (promoting healthy diet and nutrition education) and their parents (promoting nutrition knowledge) was conducted in the interventional group. Four schools, with two in each group, were randomly allocated to the intervention or control group, with 814 eligible children aged 7.1 to 12.8 years. The control group conducted myopia promotion. Differences in changes of BMI and WHtR between groups were compared with <em>t</em>-test. Mixed-effects model was used to examine the associations between changes in nutrition knowledge of children and parents with changes in children's BMI and WHtR.</p></div><div><h3>Results</h3><p>At the 6-month follow-up, the difference in changes in BMI between the intervention and control groups was 0.4 kg/m ² (<em>P</em> &lt; 0.001). At the 12-month follow-up, the difference in changes in BMI and WHtR between intervention and control groups was 0.1 kg/m² (<em>P</em> &lt; 0.001) and 0.01 kg/m² (<em>P</em> &lt; 0.001). In the intervention group, the nutrition knowledge awareness rate of children increased from 16.9% (69/409) at baseline to 21.3% (87/409) at 6-month, and 22.7% (93/409) at 12-month. The awareness rate of nutrition knowledge of parents also fluctuated, from 5.6% (23/409) to 6.6% (27/409) and 5.4% (22/409). However, the difference in changes in nutrition knowledge between intervention and control groups was non-significant. The 6-month follow-up changes in children's nutrition knowledge scores were negatively associated with changes in BMI in girls (<em>β</em> = −0.26, 95% confidence interval [<em>CI</em>]: −0.38 to −0.14, <em>P</em> &lt; 0.001), while positively associated with changes in WHtR in boys (<em>β</em> = 0.003, 95% <em>CI</em>: −0.0002 to 0.005, <em>P</em> = 0.035). The 12-month follow-up changes in children's nutrition knowledge scores were positively associated with changes in children's WHtR (<em>β</em> = 0.003, 95% <em>CI</em>: 0.0004 to 0.01, <em>P</em> = 0.018).</p></div><div><h3>Conclusions</h3><p>The intervention strategies did not reduce the BMI and WHtR of children, and the nutrition knowledge of children and parents increased after the intervention in intervention group. Changes in nutrition knowledge of children and their parents are associated with changes in children's BMI or WHtR. Interventions with a ne","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 156-163"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000537/pdfft?md5=3d985bf4e3061658a104f4fefab0eeed&pid=1-s2.0-S2414644722000537-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49207845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scoping review: obese elderly women with breast cancer and physical activity/exercise","authors":"Mark Stephan Felix","doi":"10.1016/j.glohj.2022.07.011","DOIUrl":"10.1016/j.glohj.2022.07.011","url":null,"abstract":"<div><h3>Objective</h3><p>Obesity and breast cancer (BC) are diseases of concern, especially within the context of an aging population. This scoping review is aimed at mapping out the literature on the subject of elderly women (EW) with breast cancer, obesity and physical activity/exercise (PAE) to identify gaps in the present extant literature, and to suggest directions for future research.</p></div><div><h3>Data sources</h3><p>A total of four articles were finalized from an initial 2905 articles found via searches on the <em>Annals of Internal Medicine</em> by American College of Physicians (ACP)™, BioMed Central (BMC)™, <em>BMJ</em> Journals™, <em>Journal of the American Medical Association</em> (JAMA)™, PubMed™, SAGE™, ScienceDirect™, SpringerLink (e-journals)™, Taylor and Francis Online™, and Wiley Online Library™ databases.</p></div><div><h3>Methods</h3><p>Recognized structural frameworks for scoping reviews were utilized to guide the methodology and technical aspects of this paper. Data extraction was conducted via a charting table.</p></div><div><h3>Results</h3><p>Research gaps identified include a paucity in research on the subject of obesity and breast cancer among elderly women; there is a limitation of the types of methodologies used in the research on this subject indicating vast opportunities for future studies using different methodologies; lack of use of the alternative types of physical activity and exercise such as Tai Chi, Qigong and Yoga; lack of focus on the older elderly population; and areas of social support from family and friends for obese elderly with breast cancer to engage in physical activity and exercise.</p></div><div><h3>Conclusion</h3><p>Future research would address the urgent need within academia to address the research gap of PAE and EWBC. Such research should use a diverse range of both quantitative and qualitative research methodologies, while including eastern exercise regimens such as Tai Chi, Qigong and Yoga as a means of studying PAE among EWBC. Additionally, future research may focus on the “old elderly” as a demographic group of study as well as how social support may encourage PAE among EWBC.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 129-135"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000550/pdfft?md5=e78b43833b0f02a11422b44d4d92aebf&pid=1-s2.0-S2414644722000550-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46105684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metaverse, token economies, and non-communicable diseases","authors":"Jane Thomason","doi":"10.1016/j.glohj.2022.07.001","DOIUrl":"https://doi.org/10.1016/j.glohj.2022.07.001","url":null,"abstract":"<div><p>Rapid advancements in technology and computing power, combined with the convergence of Blockchain, artificial intelligence, Internet of Things, extended reality, gamification, and decentralized finance, have led to recent growth in interest in the metaverse. Indeed today, there are more than 160 metaverse projects, and Citi estimates it could be a 13 trillion USD industry by 2030. While many have not yet grasped the relevance of the metaverse for industries, the opportunity to leverage the metaverse for health and wellness is substantial. In obesity and non-communicable disease (NCDs), there is potential to deploy the metaverse using gamification and incentives, as well as for education and care. This perspective article explores how the metaverse could be used to prevent and manage obesity and NCDs.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 164-167"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000458/pdfft?md5=94a1e528e28dc71b9afbe4b7312b8ec1&pid=1-s2.0-S2414644722000458-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138219283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community-level survey of coronavirus disease 2019 (COVID-19) preventive measures in Kwara State, Nigeria: good knowledge vs poor attitude","authors":"Nusirat Elelu ,&nbsp;Olaolu Bilewu ,&nbsp;Fatima Sanusi ,&nbsp;Ahmad Ibrahim Al-Mustapha","doi":"10.1016/j.glohj.2022.07.002","DOIUrl":"10.1016/j.glohj.2022.07.002","url":null,"abstract":"<div><h3>Background</h3><p>The public knowledge and adherence to the established coronavirus disease 2019 (COVID-19) precautionary measures are crucial to Nigeria's war against the pandemic. Public health education on its preventive practices at the grassroots level was initially crucial to achieving a lower COVID-19 incidence in Kwara State, Nigeria.</p></div><div><h3>Methods</h3><p>We assessed the knowledge of, and adherence to COVID-19 precautionary measures at the community level among 795 respondents from the three senatorial zones of Kwara State.</p></div><div><h3>Results</h3><p>54.5% (433/795) of the respondents were aged between 21 and 40 years, and 45.9% (365/795) of the respondents had a bachelor's degree or higher. Study participants had a good knowledge of COVID-19, its symptoms, and its mode of transmission. 91.8% of the respondents (730/795) had a positive perception of the COVID-19 preventive measures while 96.1% (763/795) of the respondents agreed that maintaining social distance was important in curbing the COVID-19 pandemic. However, only 38% (302/795) of them used face masks and only 25.7% (204/795) of the respondents used hand sanitizers. In addition, only 31.9% (253/795) of the respondents isolated themselves when they were ill. Multi-variable logistic regression analysis revealed that education, occupation, gender, and ethnicity were significantly associated with positive COVID-19 preventive practices among residents of Kwara State. Civil servants were more likely (<em>AOR</em>: 3.14; 95% confidence interval [<em>CI</em>]: 0.67 to 14.82; <em>P</em> = 0.034) to have positive preventive attitudes than other respondents. Study participants with tertiary education and those that were Yoruba (ethnicity) were 14.81 times more likely (95% <em>CI</em>: 4.29 to 51.05; <em>P</em> = 0.001) and 5.19 times more likely (95% <em>CI</em>: 1.82 to 14.84; <em>P</em> = 0.007) to have positive attitudes towards the laid-down COVID-19 preventive measures respectively.</p></div><div><h3>Conclusion</h3><p>The poor community adherence to the COVID-19 preventive practices could pre-dispose Kwara to more COVID-19 cases. More community engagement activities are needed to fully curb the spread of the COVID-19. Public health education should focus on preventive measures, vaccine acceptance, and community monitoring of COVID-19.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 168-173"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40584815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of overweight and obesity and preventive strategies in Pacific countries: a systematic review","authors":"Tanebu Julia Tong ,&nbsp;Masoud Mohammadnezhad ,&nbsp;Nasser Salem Alqahtani","doi":"10.1016/j.glohj.2022.07.005","DOIUrl":"10.1016/j.glohj.2022.07.005","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to explore more on contributing factors and prevention of overweight and obesity among Pacific islanders.</p></div><div><h3>Methods</h3><p>Using Cochrane library guideline, four electronic databases, PubMed, Embase, Scopus and CINAHL, were systematically searched from 2010 to 2020. Search strategy included key concepts, free text terms, and database-controlled vocabulary terms to identify articles on determinants and preventative strategies of overweight and obesity in the Pacific countries. A data extraction sheet was developed to extract relevant information required for analysis and theme development for this study.</p></div><div><h3>Results</h3><p>A total of 22 articles were summarized and categorized. Determinants of overweight and obesity identified two themes: environmental related factors 13.6% (3/22) and sociocultural related factors 27.3% (6/22). The preventative strategies of overweight and obesity was categorized into behavioural change 22.7% (5/22), school-related 18.2% (4/22), and policies 50% (11/22). The quality assessment of articles showed “Good” 68.2% (15/22), and “Fair” 31.8% (7/22).</p></div><div><h3>Conclusion</h3><p>This study highlighted two contributing, non-medication factors affecting overweight and obesity are both environmental and socio-cultural issues. Overweight and obesity preventative strategies identified in the Pacific context considered behavioural change, knowledge enhancement, and policy development. Further research should aim at exploring the current preventative strategies in-depth, to appreciate the most feasible and recommended preventative approach within the Pacific society.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 122-128"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000495/pdfft?md5=1fe5a1344d8a5f278718e889b1abfb47&pid=1-s2.0-S2414644722000495-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41649719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fighting obesity and non-communicable diseases needs different perspectives and new actions","authors":"Wen Peng ,&nbsp;Youfa Wang","doi":"10.1016/j.glohj.2022.07.010","DOIUrl":"10.1016/j.glohj.2022.07.010","url":null,"abstract":"","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 115-117"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000549/pdfft?md5=2aeacfa41c68de1065c91653c8ce073b&pid=1-s2.0-S2414644722000549-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47758174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity intervention efforts in China and the 2022 World Obesity Day","authors":"Wen Peng ,&nbsp;Jianduan Zhang ,&nbsp;Haixia Zhou ,&nbsp;An Zhang ,&nbsp;Yanxiang Wang ,&nbsp;Xiangyang Tian ,&nbsp;Deliang Wen ,&nbsp;Youfa Wang","doi":"10.1016/j.glohj.2022.07.007","DOIUrl":"10.1016/j.glohj.2022.07.007","url":null,"abstract":"<div><p>Obesity has become a serious public health problem globally. China has the world's largest number of people with obesity or overweight. More than 50% of adults and about 20% of children and adolescents in China are overweight or obese. Over the past 20 years, China has made many efforts in obesity intervention, while obesity rates continued rising. In recent years, China has taken more actions for obesity prevention. The World Obesity Day (WOD) was established in 2015 by the World Obesity Federation, and is a unified day of action calling for a cohesive, cross-sector response to fight obesity. WOD has drawn increasing attention in recent years. China formally joined the WOD activities this year, promoted by The Obesity Prevention and Control Section of Chinese Nutrition Society, which cooperated closely with other organizations in carrying out a series of activities during the 2022 WOD. These efforts aimed to encourage the whole society to pay attention to the obesity problem and take more practical actions. The activities include: (1) The 2022 “World Obesity Day” China Summit; (2) a specifically developed WOD obesity prevention education video; and (3) the launch of <em>The Expert Consensus on Obesity Prevention and Treatment in China</em>. These can serve as examples for other organizations and countries to consider in future intervention efforts. To fight the global obesity epidemic, all counties and people need to act. Countries can learn from each other's successful practices.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 3","pages":"Pages 118-121"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000513/pdfft?md5=f4f3255986ebbe61546e209ab33f01db&pid=1-s2.0-S2414644722000513-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47782891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of nutritional education on knowledge, attitude and practice regarding anemia among school children in Belgaum, India","authors":"Adhikari Poudel Sasmita ,&nbsp;Angolkar Mubashir ,&nbsp;Naik Vijaya","doi":"10.1016/j.glohj.2022.04.001","DOIUrl":"10.1016/j.glohj.2022.04.001","url":null,"abstract":"<div><h3>Background</h3><p>Anemia is a common public health problem throughout the globe with its main effect not only on health of people but also impact on socioeconomic development. A high prevalence of anemia among school children is an indication of a severe problem highlighting the necessity of proper action to prevent further deterioration. This study sought to study the impact of nutritional education on knowledge, attitude, and practice regarding anemia among school children.</p></div><div><h3>Methods</h3><p>This is an interventional study among school children of Kendriye Vidyalaya, No. 2 Belgaum district, India. Structured and self-administered questionnaires were used to know the knowledge, attitude and practice of student anemia. The data were analyzed using paired <em>t</em>-test and McNemar test.</p></div><div><h3>Results</h3><p>There was significant increment in the mean knowledge and attitude scores of the school children at the post-test evaluation.  Overall increase of 51.2% in mean score of knowledge and overall increase of 20.7% in mean score of attitudes was found (<em>P</em> &lt; 0.05). Increase in frequency of consumption pattern of iron rich foods especially ragi, jaggery, green leafy vegetables and sprouted grains was reported.</p></div><div><h3>Conclusion</h3><p>The nutritional education resulted in improvement of knowledge and change in attitude regarding anemia as well as increase in consumption of foods rich in Iron. Therefore, nutritional education is one of the cost-effective and sustainable method for lowering the cases of anemia.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 2","pages":"Pages 91-94"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2414644722000264/pdfft?md5=e8857746e3f01de31351b687e3703e0f&pid=1-s2.0-S2414644722000264-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48407749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced therapy of overweight or obese polycystic ovary syndrome: a prospective study","authors":"Min Min ,&nbsp;Xiangyan Ruan ,&nbsp;Alfred O. Mueck","doi":"10.1016/j.glohj.2022.04.004","DOIUrl":"10.1016/j.glohj.2022.04.004","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the effects of orlistat combined with drospirenone/ethinylestradiol tablets (DRSP/EE) on anthropometric indices, sexual hormones, hepatorenal function parameters of overweight or obese patients with polycystic ovary syndrome (PCOS).</p></div><div><h3>Methods</h3><p>75 overweight or obese PCOS patients [body mass index (BMI) ≥ 24 kg/m²] were recruited within the Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, from April 2019 to January 2020, for a prospective, randomized, open-labelled comparing study. They were numbered one by one according to the order of recruitement and randomly divided into two groups, group 1 included 50 patients, orlistat plus DRSP/EE; group 2 included 25 patients treated with DRSP/EE alone. Both groups got the same comprehensive intervention in terms of individualized, standardized managment and monitoring of life-style like diet and exercise. The changes of anthropometric indices, sexual hormones, hepatorenal function parameters before and after three months of treatment in the two groups were compared .</p></div><div><h3>Results</h3><p>After three months of treatment, body weight, waist circumference (WC), hip circumference (HC) and BMI of both groups were significantly decreased (<em>P</em> &lt; 0.05). The decrease of body weight, WC, HC and BMI in group 1 was significantly greater than those in group 2 (<em>P</em> &lt; 0.05). Free testosterone and sex hormone–binding globulin in both groups were significantly changed (<em>P</em> &lt; 0.05). There was no significant difference in the hepatorenal function parameters between the two groups after three months treatment (<em>P</em> &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>To our knowledge our study is the first to investigate the effects of orlistat combined with DRSP/EE in overweight or obese PCOS patients comparing with the effect of using DRSP/EE alone. Orlistat combined with DRSP/EE was better than use DRSP/EE alone in getting weight loss, which provides an evidence for the choice of rational drug use in clinical practice.</p></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"6 2","pages":"Pages 75-79"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S241464472200029X/pdfft?md5=998212a9c50fe5dc8c1119511bc9c5c4&pid=1-s2.0-S241464472200029X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43021682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}