Global health journal (Amsterdam, Netherlands)最新文献

{"title":"Parsing pathways from chronic illness to self-rated health in Egypt: the role of mental well-being","authors":"Yusra Alkasasbeh","doi":"10.1016/j.glohj.2025.11.006","DOIUrl":"10.1016/j.glohj.2025.11.006","url":null,"abstract":"<div><h3>Objective</h3><div>Chronic noncommunicable conditions are a major driver of poor health in low- and middle-income countries, yet the mental health pathways through which these illnesses shape perceived health remain underexamined. This study investigates whether recent mental well-being—measured using the World Health Organization Five-Item Well-Being Index (WHO-5)—mediates the association between chronic illness and self-rated health (SRH) among Egyptian adults aged 32–65.</div></div><div><h3>Methods</h3><div>This study uses nationally representative data from the 2023 Egypt Labor Market Panel Survey (<em>n</em> = 23,044) and estimates survey-weighted Ordinary Least Squares models predicting SRH (1 = very good/excellent to 5 = very bad). The key independent variable is chronic illness status. Mediation analysis is conducted using the Sobel–Goodman method with 1000 bootstrap replicates. All models adjust for sociodemographic covariates including age, sex, education, marital status, and regional residence.</div></div><div><h3>Results</h3><div>Chronic illness is associated with significantly worse SRH (<em>β</em> = 0.59, standard error [<em>SE</em>] = 0.02, <em>P</em> &lt; 0.001). When mental well-being is added to the model, the chronic illness coefficient declines to 0.50 (<em>SE</em> = 0.02, <em>P</em> &lt; 0.001), and WHO-5 is independently associated with better SRH (<em>β</em> = ‒0.22, <em>SE</em> = 0.01, <em>P</em> &lt; 0.001). The indirect effect via WHO-5 is 0.08 (<em>SE</em> = 0.01, <em>P</em> &lt; 0.001), indicating that 14.2% of the total association is mediated through recent psychological well-being.</div></div><div><h3>Conclusion</h3><div>Although most of the self-rated health disadvantage linked to chronic illness flows through somatic and functional channels, mental well-being accounts for a meaningful share. Incorporating WHO-5 screening and stepped referral into chronic care could improve subjective health outcomes in Egypt. Mental health integration should be viewed as a critical component of equitable noncommunicable disease strategies.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 323-329"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat exposure, physiological strain, and wet bulb globe temperature prediction among outdoor agricultural workers in Pak Chong, Thailand","authors":"Pirutchada Musigapong ,&nbsp;Tosaphol Ratniyomchai ,&nbsp;Kiattisak Batsungnoen ,&nbsp;Thanatchai Kulworawanichpong ,&nbsp;Aduldatch Sailabaht","doi":"10.1016/j.glohj.2025.11.004","DOIUrl":"10.1016/j.glohj.2025.11.004","url":null,"abstract":"<div><h3>Objective</h3><div>This study assessed heat exposure, physiological responses, and the risk of chronic kidney disease among outdoor agricultural workers in Pak Chong, Thailand, and developed a predictive model for Wet Bulb Globe Temperature (WBGT).</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 170 agricultural workers. Field WBGT was measured at 33 locations in April and July and corrected for Clothing Adjustment Factor to determine effective WBGT. Core temperature, skin temperature, heart rate, blood pressure, and body weight were monitored before, during, and after work shifts. Urine dipstick and microalbumin tests were performed to evaluate dehydration and kidney disorder. Workloads were classified according to American Conference of Governmental Industrial Hygienists (ACGIH) metabolic rate categories. Meteorological data were used to train machine learning models—including linear regression, decision tree, random forest, and extreme gradient boosting—to predict WBGT values.</div></div><div><h3>Results</h3><div>Effective WBGT at fruit gardens and field crops sites frequently exceeded ACGIH limits for moderate-to-heavy work. Workers’ systolic/diastolic blood pressure and heart rate increased during work (transient cardiovascular strain) while body temperature remained stable. Post-shift, 34.7% showed moderate dehydration; microalbumin screening was positive in 31/170 (18.2%) suggesting possible early renal involvement but not chronic kidney disease diagnosis. Among the predictive models, extreme gradient boosting achieved the best performance (root mean square error = 0.798 °C, mean absolute error = 0.576 °C, <em>R²</em> = 0.81). The most influential predictors were air temperature, sunshine duration, and site-specific factors.</div></div><div><h3>Conclusions</h3><div>Agricultural workers in Pak Chong are frequently exposed to heat stress that exceeds ACGIH standards, predisposing them to dehydration and kidney impairment. The findings support evidence-based preventive strategies such as regulated work–rest cycles, hydration management, and medical surveillance. Moreover, the validated WBGT prediction tool offers a practical approach for real-time monitoring and proactive climate adaptation to protect outdoor workers in heat-prone environments.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 291-300"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of private equity investments in Indian healthcare: a critical political economy perspective on equity, access, and rising health costs","authors":"Vivek Nenmini Dileep","doi":"10.1016/j.glohj.2025.12.001","DOIUrl":"10.1016/j.glohj.2025.12.001","url":null,"abstract":"<div><h3>Background</h3><div>The Indian healthcare sector has undergone significant transformations due to private equity (PE) investments. The influx of capital has facilitated the expansion of infrastructure and improvement in services, particularly in urban and semi-urban areas. However, this transformation raises critical concerns regarding equity in healthcare access, rising health costs, and the potential commercialization of healthcare services.</div></div><div><h3>Methods</h3><div>Employing a critical political economy approach, this study examines the effects of PE investments in Indian healthcare. It integrates theories from Antonio Gramsci, David Harvey and Nancy Fraser to analyze the implications of these investments. The research draws on secondary data from industry reports, government statistics and academic literature to assess the trends, impacts and policy responses related to PE in healthcare.</div></div><div><h3>Results</h3><div>PE investments have led to increased privatization, rising healthcare costs and a focus on profit-driven models. Despite expanding infrastructure, access to quality healthcare remains inequitable, particularly for marginalized and rural populations. The analysis highlights the tension between capital accumulation and public health needs, showing how PE investments prioritize profitability over equity. The commodification of healthcare reflects broader neoliberal policies that undermine public health objectives and exacerbate inequalities.</div></div><div><h3>Conclusion</h3><div>While PE investments drive innovation and expansion, they also pose challenges to affordability and equitable access. Policy interventions are necessary to regulate PE investments and ensure that healthcare remains accessible and equitable for all.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 259-264"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and determinants of preterm birth and neonatal mortality in Ghana (2008–2022): a WHO antenatal care guidelines analysis","authors":"Kasuni H.M. Akalanka ,&nbsp;Kelly Lin ,&nbsp;Jing Sun","doi":"10.1016/j.glohj.2025.11.005","DOIUrl":"10.1016/j.glohj.2025.11.005","url":null,"abstract":"<div><h3>Background</h3><div>Preterm birth and neonatal mortality continue to pose significant public health challenges in Ghana. This study explores their temporal trends and associated determinants from 2008 to 2022.</div></div><div><h3>Methods</h3><div>Birth record data from the Ghana Demographic and Health Surveys (2008, 2014, and 2022) were used to analyse trends and determinants in neonatal mortality and preterm birth aligned with World Health Organization antenatal care (ANC) guidelines using Pearson’s Chi-square test and multivariate logistic regression with statistical significance at <em>P</em> &lt; 0.05 and 95 % confidence intervals (<em>CI</em>).</div></div><div><h3>Results</h3><div>Preterm birth rate and neonatal mortality rate decreased from 13.0 % to 9.1 % and 27.6 to 23.7 per 1000 live births from 2008 to 2022 respectively. Lack of iron supplementation (odds ratio [<em>OR</em>]1.127, 95 % <em>CI</em>: 1.047 to 1.967) a nutritional intervention maternal assessments (moderate/severe anaemia (<em>OR</em> 1.423, 95 % <em>CI</em>: 1.178 to 2.051), preventive measures (Untreated malaria (<em>OR</em> 1.449, 95 % <em>CI</em>: 1.104 to 2.411) or deworming (<em>OR</em> 1.267, 95 % <em>CI</em>: 0.970 to 1.645) were associated with increased preterm birth risk. Attending &lt; 8 ANC visits raised the odds of preterm birth (<em>OR</em> 1.24, 95 % <em>CI</em>: 1.03 to 1.257) and neonatal mortality (<em>OR</em> 1.583, 95 % <em>CI</em>: 1.120 to 2.480).</div></div><div><h3>Conclusion</h3><div>Despite reductions in preterm birth and neonatal mortality rates, substantial gaps in antenatal care remain. Strengthening the implementation of World Health Organization ANC guidelines is critical to reducing preterm birth and neonatal mortality in Ghana.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 344-354"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic disparities in outpatient treatment utilization among Indonesian older adults: findings from the 2015 and 2020 National Socioeconomic Survey","authors":"Mardiana Dwi Puspitasari ,&nbsp;Mugia Bayu Rahardja","doi":"10.1016/j.glohj.2025.12.002","DOIUrl":"10.1016/j.glohj.2025.12.002","url":null,"abstract":"<div><h3>Introduction</h3><div>With an aging population, Indonesia must monitor health inequities and promote healthy aging. This study explores the trends and disparities in outpatient treatment utilization among Indonesian older adults across socioeconomic position (SEP), following the implementation of universal health coverage in 2014.</div></div><div><h3>Methods</h3><div>The unit of analysis includes 27,708 and 29,905 non-institutionalized Indonesian older adults aged 60 and over with poor self-rated health status residing in 413 and 514 districts, respectively. The data were obtained from the combined datasets of the 2015 National Socioeconomic Survey (SUSENAS) and 2014 Village Data Census (PODES), as well as the 2020 SUSENAS and 2021 PODES.. Outpatient treatment utilization is the outcome variable. SEP is assessed by household wealth index and educational attainment. The slope index of inequality (SII) is calculated using multilevel-adjusted prevalence estimates (<em>P</em> &lt; 0.05).</div></div><div><h3>Results</h3><div>After adjusting for age, health insurance, and percentage of villages in district with primary care services, older adults in the highest SEP accessed outpatient more than those in the lowest SEP in both 2015 (<em>P</em> &lt; 0.001 for education and for wealth) and 2020 (<em>P</em> &lt; 0.001 for education and for wealth). The SII revealed a statistically significant increase in the disparity in outpatient between the highest and lowest educational levels from 2015 (14.1 %, <em>P</em> &lt; 0.001) to 2020 (16.9 %, <em>P</em> &lt; 0.001). The proportions of older adults with both the highest (−7.2 %, <em>P</em> &lt; 0.001) and lowest (−9.4 %, <em>P</em> &lt; 0.001) education levels accessing outpatient decreased. Between 2015 and 2020, the SII demonstrated a statistically significant decrease in the disparity between the highest (15.2 %, <em>P</em> = 0.01) and lowest (12.4 %, <em>P</em> = 0.03) wealth groups. The proportion of older adults in both the highest (−7.1 %, <em>P</em> &lt; 0.001) and lowest (−5.8 %, <em>P</em> &lt; 0.001) wealth groups accessing outpatient declined.</div></div><div><h3>Conclusion</h3><div>Macro-level policy interventions aimed at increasing outpatient treatment coverage should target all older adults, regardless of SEP. Further research into the broader macro-social context is warranted.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 330-336"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare utilization patterns in Indonesia: insights from the 2023 National Socio-economic Survey","authors":"Haerawati Idris,&nbsp;Rizqa Fitri Damaiasa,&nbsp;Hamzah Hasyim","doi":"10.1016/j.glohj.2025.12.004","DOIUrl":"10.1016/j.glohj.2025.12.004","url":null,"abstract":"<div><h3>Objective</h3><div>Unmet need for health services in Indonesia has increased significantly, reaching 6.09 % and representing the highest rate observed over the past 5 years. The number of people who have health complaints but do not access health services will certainly affect the degree of public health. This study investigates patterns of outpatient and inpatient healthcare utilization in Indonesia</div></div><div><h3>Methods</h3><div>This was a cross-sectional study using data from the 2023 National Socio-Economic Survey. The analysis included respondents aged ≥ 19 years 211,583 for outpatient services and 806,982 for inpatient services. Univariate, bivariate chi-square, and multivariate log-binomial regression analyses were conducted to identify determinants of healthcare utilization, including demographic, socioeconomic, and regional factors.</div></div><div><h3>Results</h3><div>Outpatient services were utilized by 34.0 % of respondents, while inpatient services were utilized by 3.6 %. Outpatient services were predominantly used by elderly individuals (aged ≥ 60 years), whereas inpatient services were more commonly utilized by those with health complaints.</div></div><div><h3>Conclusion</h3><div>The study underscores the importance of targeted health education initiatives and government-sponsored screening programs to address healthcare disparities and promote early detection of health issues. By improving awareness and equitable healthcare access, these efforts can contribute to effective health management and better public health outcomes</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 285-290"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"If Europe lived the same lifestyle: insights into cardiovascular risk from the European Social Survey","authors":"Michal Valko ,&nbsp;Mark David Walker ,&nbsp;April Htoon ,&nbsp;Jocelyn Dumlao ,&nbsp;Hakan Lane ,&nbsp;Isabella G. Lee ,&nbsp;Huda Amer ,&nbsp;Janka Bursova","doi":"10.1016/j.glohj.2025.11.002","DOIUrl":"10.1016/j.glohj.2025.11.002","url":null,"abstract":"<div><h3>Background</h3><div>Cardiovascular disease remains the leading cause of mortality across the European region. Despite marked regional variations, cross-national differences in underlying risk factors have received comparatively little attention.</div></div><div><h3>Objective</h3><div>To use European Social Survey, a unique cross-European dataset, to examine regional patterns in prevalence and lifestyle risks.</div></div><div><h3>Methods</h3><div>This study employs clustering analysis and nested logistic modelling. Counterfactual analysis was conducted to illustrate how lifestyle modifications could reduce risk.</div></div><div><h3>Results</h3><div>The prevalence of heart problems was highest in Latvia (25.6 %, 95 % <em>CI</em>: 23.0 to 28.2), Lithuania (17.6 %, 95 % <em>CI</em>: 15.5 to 19.7), and Bulgaria (14.9 %, 95 % <em>CI</em>: 13.4 to 19.4). Regionally, heart problems were higher in Northern and Eastern Europe (15 % and 11.9 %) than Western and Southern Europe (10.8 % and 9.5 %). Among the risk factors, modelling emphasised the importance of modifiable factors including education, body mass index and physical activity.</div></div><div><h3>Conclusion</h3><div>The results underline that cardiovascular disease is influenced by interrelated socioeconomic, environmental and lifestyle determinants. Public policy interventions could be targeted at those countries where greatest reductions are obtainable and concentrate on interventions on those lifestyle traits identified. The study utilised a social science dataset, thereby illustrating how multidisciplinary resources can benefit epidemiological research.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 301-313"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of emotional labor in occupational identity and work engagement among Portuguese firefighters: implications for crisis management","authors":"Ana Luísa Sousa Pinto ,&nbsp;Carla Maria Santos de Carvalho ,&nbsp;Soraia Alexandra de Sousa Oliveira ,&nbsp;Ana Karina Sousa Fernandes","doi":"10.1016/j.glohj.2025.12.005","DOIUrl":"10.1016/j.glohj.2025.12.005","url":null,"abstract":"<div><h3>Objective</h3><div>To examine how emotional labor demands and strategies influence work engagement and occupational identity among Portuguese volunteer firefighters.</div></div><div><h3>Methods</h3><div>Participants completed the Emotional Work Requirements Scale, Emotional Labour Scale, Utrecht Work Engagement Scale, and Social Identity Scale. Multiple linear regression analyses were conducted to assess the predictive effects of emotional labor demands and strategies on work engagement and occupational identity.</div></div><div><h3>Results</h3><div>Emotional labor explained 11.8 % of the variance in work engagement and 10.9 % in occupational identity. Positive emotion expression significantly predicted higher work engagement and a stronger occupational identity, while the suppression of negative emotions predicted a weaker occupational identity. Other emotional labor dimensions were not significant.</div></div><div><h3>Conclusions</h3><div>Findings underscore the dual role of emotional labor—as a resource when positive emotions are expressed and as a strain when negative emotions are habitually suppressed. Targeted interventions to promote authentic positive expression and effective emotional processing may enhance firefighters’ well-being, strengthen crisis team performance, and benefit the communities they serve. Further research is needed to deepen the understanding of emotional labor in crisis response contexts.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 337-343"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “The intersection of mpox outbreak and mental health: a bibliometric analysis of current research trends” [Global Health Journal 9 (2025) 124–135]","authors":"Ovinuchi Ejiohuo ,&nbsp;Cyril Onwuelazu Uteh ,&nbsp;Olubusola O. Olaleye ,&nbsp;Samuel Adefisoye Lawal ,&nbsp;Abdulkadir Yusif Maigoro ,&nbsp;Helen Onyeaka","doi":"10.1016/j.glohj.2025.07.001","DOIUrl":"10.1016/j.glohj.2025.07.001","url":null,"abstract":"","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Page 359"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Wolbachia-containing mosquito release on dengue control: a systems dynamics approach for health policy development","authors":"Laura Valentina Bocanegra-Villegas ,&nbsp;Sandra Patricia Usaquen-Perilla ,&nbsp;Mauricio Alejandro Gómez-Figueroa","doi":"10.1016/j.glohj.2025.11.003","DOIUrl":"10.1016/j.glohj.2025.11.003","url":null,"abstract":"<div><h3>Background</h3><div>This article examines the impact of the release of <em>Wolbachia</em>-infected population replacement mosquitoes as an innovative strategy for managing and controlling dengue in the Americas, using an approach based on the system dynamics methodology. The introduction of <em>Wolbachia</em>-carrying mosquitoes aims to reduce dengue transmission by interfering with the reproductive capacity of mosquitoes, thus limiting the spread of the virus.</div></div><div><h3>Objective</h3><div>the objective of this study is to analyze how this intervention affects not only the incidence of dengue but also the health care system, evaluating changes in the demand for medical services and the costs associated with treatment in health care institutions. Specifically, it looks at the cost per visit to an Epidemiologist, a Family Doctor, diagnostic tests, and hospitalization.</div></div><div><h3>Methods</h3><div>the study uses simulation scenarios to model the potential impact of the <em>Wolbachia</em>-based intervention in reducing dengue cases and its associated health and economic burden. The scenarios also assess the optimization of resources and improvements in the health system's response to epidemic outbreaks. The simulation model utilizes real data from the Americas region to enhance the accuracy and relevance of the results.</div></div><div><h3>Conclusion</h3><div>The results the potential of the release of <em>Wolbachia</em>-carrying mosquitoes to significantly mitigate the health and economic burden of dengue, with a maximum saving of 60.15% in the best simulation scenario. The approach not only highlights scientific innovation but also demonstrates its potential influence on public policy design. The findings support the implementation of sustainable strategies to maximize the benefits of this intervention and ensure its effective integration into public health programs, contributing to better long-term dengue management.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 4","pages":"Pages 314-322"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145845683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}