发布求助
文献互助 智能选刊 最新文献

Genome instability & disease最新文献

筛选
英文 中文
MicroRNA-mediated reprogramming of glucose, fatty acid and amino acid metabolism in cancer 微rna介导的肿瘤中葡萄糖、脂肪酸和氨基酸代谢重编程
Genome instability & disease Pub Date : 2022-08-26 DOI: 10.1007/s42764-022-00078-x
Jie Ding, Yifan Wen, Xu Yuan, Xianghuo He
{"title":"MicroRNA-mediated reprogramming of glucose, fatty acid and amino acid metabolism in cancer","authors":"Jie Ding, Yifan Wen, Xu Yuan, Xianghuo He","doi":"10.1007/s42764-022-00078-x","DOIUrl":"https://doi.org/10.1007/s42764-022-00078-x","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"4 1","pages":"47-69"},"PeriodicalIF":0.0,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48090782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FAM135B: a new player in DNA damage response FAM135B：DNA损伤反应的新参与者
Genome instability & disease Pub Date : 2022-08-22 DOI: 10.1007/s42764-022-00079-w
C. Song, Lin Deng
{"title":"FAM135B: a new player in DNA damage response","authors":"C. Song, Lin Deng","doi":"10.1007/s42764-022-00079-w","DOIUrl":"https://doi.org/10.1007/s42764-022-00079-w","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"3 1","pages":"238-240"},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46296393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accurate prediction of stomach adenocarcinomas of poorest and best prognosis with a combination of gene expression and clinical signatures 结合基因表达和临床特征准确预测胃腺癌最差和最佳预后
Genome instability & disease Pub Date : 2022-08-19 DOI: 10.1007/s42764-022-00077-y
Lingyu Qiu, Huayu Kang, Jie-lin Yang, Yidong Zheng, Aiyue Chen, Chunlin Chen, Xinlong Wang, Qiongfang Fang, Weifang Zhu, Ou Sha, Yejun Wang
{"title":"Accurate prediction of stomach adenocarcinomas of poorest and best prognosis with a combination of gene expression and clinical signatures","authors":"Lingyu Qiu, Huayu Kang, Jie-lin Yang, Yidong Zheng, Aiyue Chen, Chunlin Chen, Xinlong Wang, Qiongfang Fang, Weifang Zhu, Ou Sha, Yejun Wang","doi":"10.1007/s42764-022-00077-y","DOIUrl":"https://doi.org/10.1007/s42764-022-00077-y","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"3 1","pages":"227-237"},"PeriodicalIF":0.0,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43653131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Centrosome, microtubule and DNA damage response 中心体，微管和DNA损伤反应
Genome instability & disease Pub Date : 2022-06-01 DOI: 10.1007/s42764-022-00068-z
Dingwei Li, Xiuwen Liu, Qiang Chen
{"title":"Centrosome, microtubule and DNA damage response","authors":"Dingwei Li, Xiuwen Liu, Qiang Chen","doi":"10.1007/s42764-022-00068-z","DOIUrl":"https://doi.org/10.1007/s42764-022-00068-z","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"3 1","pages":"163-171"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52772854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Genotoxicity testing and recent advances 基因毒性测试及其最新进展
Genome instability & disease Pub Date : 2022-02-01 DOI: 10.1007/s42764-021-00058-7
Yang Luan, M. Honma
{"title":"Genotoxicity testing and recent advances","authors":"Yang Luan, M. Honma","doi":"10.1007/s42764-021-00058-7","DOIUrl":"https://doi.org/10.1007/s42764-021-00058-7","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"3 1","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52772613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The role of ral signaling and post translational modifications (PTMs) of Ras in cancer Ras的信号转导和翻译后修饰(PTMs)在癌症中的作用
Genome instability & disease Pub Date : 2022-02-01 DOI: 10.1007/s42764-022-00059-0
Mohammad Reza Zinatizadeh, Peyman Kheirandish Zarandi, Mahsa Keshavarz-Fathi, Mohammadmehdi Yousefi, N. Rezaei
{"title":"The role of ral signaling and post translational modifications (PTMs) of Ras in cancer","authors":"Mohammad Reza Zinatizadeh, Peyman Kheirandish Zarandi, Mahsa Keshavarz-Fathi, Mohammadmehdi Yousefi, N. Rezaei","doi":"10.1007/s42764-022-00059-0","DOIUrl":"https://doi.org/10.1007/s42764-022-00059-0","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"3 1","pages":"22-32"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52772688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dynamic recruitment of UFM1-specific peptidase 2 to the DNA double-strand breaks regulated by WIP1. 在 WIP1 的调控下，UFM1 特异性肽酶 2 被动态招募到 DNA 双链断裂处。
Genome instability & disease Pub Date : 2022-01-01 Epub Date: 2022-08-10 DOI: 10.1007/s42764-022-00076-z
Bo Qin, Jia Yu, Fei Zhao, Jinzhou Huang, Qin Zhou, Zhenkun Lou
{"title":"Dynamic recruitment of UFM1-specific peptidase 2 to the DNA double-strand breaks regulated by WIP1.","authors":"Bo Qin, Jia Yu, Fei Zhao, Jinzhou Huang, Qin Zhou, Zhenkun Lou","doi":"10.1007/s42764-022-00076-z","DOIUrl":"10.1007/s42764-022-00076-z","url":null,"abstract":"<p><p>The ufmylation ligase-UFL1 promotes ATM activation by monoufmylating H4 at K31 in a positive-feedback loop after double-strand breaks (DSB) occur, whereas UFM1 Specific Peptidase 2 (UfSP2) suppresses ATM activation, but the mechanism of recruitment of UfSP2 to the DSB finetuning DNA damage response is still not clear. Here, we report that UfSP2 foci formation is delayed compared to UFL1 foci formation following the radiation insult. Mechanistically, UfSP2 binds to the MRN complex in absence of DSB. Irradiation-induced phosphorylation of UfSP2 by ATM leads to the dissociation of UfSP2 from the MRN complex. This phosphorylation can be removed by the phosphatase WIP1, thereby UfSP2 is recruited to the DSBs, deufmylating H4 and suppressing ATM activation. In summary, we identify a mechanism of delicately negative modulation of ATM activation by UfSP2 and rewires ATM activation pathways.</p>","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"3 4","pages":"217-226"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10096568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Chromosome instability induced by mutations in TAD anchors leads to tumors 更正:由TAD锚点突变引起的染色体不稳定导致肿瘤
Genome instability & disease Pub Date : 2021-12-01 DOI: 10.1007/s42764-021-00054-x
A. N. Luchnik
{"title":"Correction to: Chromosome instability induced by mutations in TAD anchors leads to tumors","authors":"A. N. Luchnik","doi":"10.1007/s42764-021-00054-x","DOIUrl":"https://doi.org/10.1007/s42764-021-00054-x","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"2 1","pages":"330"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43045507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Terpenoids-enriched fraction of Celastrus orbiculatus sensitizes gemcitabine by disrupting Chk1/RAD51-mediated DNA damage response in pancreatic cancer 环芹的萜类化合物富集部分通过破坏Chk1/ rad51介导的胰腺癌DNA损伤反应使吉西他滨增敏
Genome instability & disease Pub Date : 2021-11-24 DOI: 10.1007/s42764-021-00055-w
Yang Zhao, Zhuangzhuang Jiang, Tengyang Ni, Wei Jiang, Kehui Zhou, Yuping Liu, Yanqing Liu, Tao Li
{"title":"Terpenoids-enriched fraction of Celastrus orbiculatus sensitizes gemcitabine by disrupting Chk1/RAD51-mediated DNA damage response in pancreatic cancer","authors":"Yang Zhao, Zhuangzhuang Jiang, Tengyang Ni, Wei Jiang, Kehui Zhou, Yuping Liu, Yanqing Liu, Tao Li","doi":"10.1007/s42764-021-00055-w","DOIUrl":"https://doi.org/10.1007/s42764-021-00055-w","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"2 6","pages":"358-373"},"PeriodicalIF":0.0,"publicationDate":"2021-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147884076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Correction to: TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity 修正:TIP60将SUV39H1招募到染色质上，以维持异染色质基因组的稳定性并抵抗过氧化氢诱导的细胞毒性
Genome instability & disease Pub Date : 2021-08-01 DOI: 10.1007/s42764-020-00029-4
Bo Tu, Yantao Bao, Ming Tang, Qian Zhu, Xiaopeng Lu, Hui Wang, Tianyun Hou, Ying Zhao, Ping Zhang, Wei-Guo Zhu
{"title":"Correction to: TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity","authors":"Bo Tu, Yantao Bao, Ming Tang, Qian Zhu, Xiaopeng Lu, Hui Wang, Tianyun Hou, Ying Zhao, Ping Zhang, Wei-Guo Zhu","doi":"10.1007/s42764-020-00029-4","DOIUrl":"https://doi.org/10.1007/s42764-020-00029-4","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":"2 1","pages":"261"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s42764-020-00029-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45688098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书