发布求助
文献互助 智能选刊 最新文献

Genome instability & disease最新文献

筛选
英文 中文
MiR-146a induces the aging of mesenchymal stem cell via CASK MiR-146a 通过 CASK 诱导间充质干细胞衰老
Genome instability & disease Pub Date : 2024-01-17 DOI: 10.1007/s42764-023-00119-z
Yanxia Zhu, Jia Liu, Yiyang Liu, Junyu Su, Kangling Xu, Guangqian Zhou
{"title":"MiR-146a induces the aging of mesenchymal stem cell via CASK","authors":"Yanxia Zhu, Jia Liu, Yiyang Liu, Junyu Su, Kangling Xu, Guangqian Zhou","doi":"10.1007/s42764-023-00119-z","DOIUrl":"https://doi.org/10.1007/s42764-023-00119-z","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of H3K27me3 methylation in cancer development H3K27me3 甲基化在癌症发展中的作用
Genome instability & disease Pub Date : 2024-01-04 DOI: 10.1007/s42764-023-00118-0
Longjiang Di, Weiguo Zhu
{"title":"The role of H3K27me3 methylation in cancer development","authors":"Longjiang Di, Weiguo Zhu","doi":"10.1007/s42764-023-00118-0","DOIUrl":"https://doi.org/10.1007/s42764-023-00118-0","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139384701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
H3K9me3 asymmetry: epigenetic choreography in DNA replication for genomic stability H3K9me3 不对称：DNA 复制中的表观遗传学编排促进基因组稳定
Genome instability & disease Pub Date : 2023-11-28 DOI: 10.1007/s42764-023-00117-1
Wei-Guo Zhu
{"title":"H3K9me3 asymmetry: epigenetic choreography in DNA replication for genomic stability","authors":"Wei-Guo Zhu","doi":"10.1007/s42764-023-00117-1","DOIUrl":"https://doi.org/10.1007/s42764-023-00117-1","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139217688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Chromatin-based DNA replication initiation regulation in eukaryotes 更正：真核生物中基于染色质的 DNA 复制启动调控
Genome instability & disease Pub Date : 2023-11-27 DOI: 10.1007/s42764-023-00114-4
Lei Hao, Ruixin Fang, Haizhen Long
{"title":"Correction: Chromatin-based DNA replication initiation regulation in eukaryotes","authors":"Lei Hao, Ruixin Fang, Haizhen Long","doi":"10.1007/s42764-023-00114-4","DOIUrl":"https://doi.org/10.1007/s42764-023-00114-4","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139233348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An integrated pan-cancer analysis of leucine-rich repeat containing protein 59: a potential biomarker for prognostic and immunotherapy 富含亮氨酸重复蛋白 59 的泛癌症综合分析：预后和免疫疗法的潜在生物标记物
Genome instability & disease Pub Date : 2023-11-21 DOI: 10.1007/s42764-023-00113-5
Meiqi Zeng, Xia Wang, Xiaona Wang, Yuning Zhang, Zhenguang Ying, Lixin Xia, Feng Gao, Xianxiong Chen, Kin Yip Tam, Long Xu, Ou Sha
{"title":"An integrated pan-cancer analysis of leucine-rich repeat containing protein 59: a potential biomarker for prognostic and immunotherapy","authors":"Meiqi Zeng, Xia Wang, Xiaona Wang, Yuning Zhang, Zhenguang Ying, Lixin Xia, Feng Gao, Xianxiong Chen, Kin Yip Tam, Long Xu, Ou Sha","doi":"10.1007/s42764-023-00113-5","DOIUrl":"https://doi.org/10.1007/s42764-023-00113-5","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139251459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PDHE1α in DNA damage repair: a critical chromatin acetylation regulator PDHE1α在DNA损伤修复中的作用:一个关键的染色质乙酰化调节因子
Genome instability & disease Pub Date : 2023-11-11 DOI: 10.1007/s42764-023-00112-6
Bingsong Huang, Yuping Chen, Jian Yuan
{"title":"PDHE1α in DNA damage repair: a critical chromatin acetylation regulator","authors":"Bingsong Huang, Yuping Chen, Jian Yuan","doi":"10.1007/s42764-023-00112-6","DOIUrl":"https://doi.org/10.1007/s42764-023-00112-6","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135041705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of protein arginine methylation 5 in DNA damage repair and cancer therapy 蛋白精氨酸甲基化5在DNA损伤修复和癌症治疗中的作用
Genome instability & disease Pub Date : 2023-11-08 DOI: 10.1007/s42764-023-00111-7
Qikun Gao, Ziyi Liu, Jinyang Liu, Xuyang Yan, Junfei Dai, Zixuan Zhang, Rongxiao Li, Shiva Basnet, Changzheng Du
{"title":"The role of protein arginine methylation 5 in DNA damage repair and cancer therapy","authors":"Qikun Gao, Ziyi Liu, Jinyang Liu, Xuyang Yan, Junfei Dai, Zixuan Zhang, Rongxiao Li, Shiva Basnet, Changzheng Du","doi":"10.1007/s42764-023-00111-7","DOIUrl":"https://doi.org/10.1007/s42764-023-00111-7","url":null,"abstract":"Abstract Protein arginine methylation, a post-translational modification (PTM), is fundamental in regulating protein function and stability. Among the nine protein methyl transferases (PRMT), PRMT5 plays a critical role in promoting oncogenic processes including tumor proliferation, invasiveness, immune escape and DNA damage repair through different signaling pathways. It is also a target in cancer therapy, with numerous inhibitors in clinical trial. In this review, we focus on the biological functions of PRMT5 in DNA damage repair and maintenance of genome stability in cancer, and summarize the development advance of PRMT5 inhibitors in cancer therapy.","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135390057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemotherapy-induced neuronal DNA damage: an intriguing toolbox to elucidate DNA repair mechanisms in the brain 化疗诱导的神经元DNA损伤:阐明大脑中DNA修复机制的有趣工具箱
Genome instability & disease Pub Date : 2023-11-06 DOI: 10.1007/s42764-023-00110-8
Aishwarya Babu, Madhusoodanan Urulangodi
{"title":"Chemotherapy-induced neuronal DNA damage: an intriguing toolbox to elucidate DNA repair mechanisms in the brain","authors":"Aishwarya Babu, Madhusoodanan Urulangodi","doi":"10.1007/s42764-023-00110-8","DOIUrl":"https://doi.org/10.1007/s42764-023-00110-8","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135584770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chromatin-based DNA replication initiation regulation in eukaryotes 真核生物染色质DNA复制起始调控
Genome instability & disease Pub Date : 2023-10-13 DOI: 10.1007/s42764-023-00108-2
Lei Hao, Ruixin Fang, Haizhen Long
{"title":"Chromatin-based DNA replication initiation regulation in eukaryotes","authors":"Lei Hao, Ruixin Fang, Haizhen Long","doi":"10.1007/s42764-023-00108-2","DOIUrl":"https://doi.org/10.1007/s42764-023-00108-2","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135853654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel insights into DNA damage repair defects in HPV-positive head and neck squamous cell carcinoma: from the molecular basis to therapeutic opportunities 对hpv阳性头颈部鳞状细胞癌DNA损伤修复缺陷的新见解:从分子基础到治疗机会
Genome instability & disease Pub Date : 2023-10-11 DOI: 10.1007/s42764-023-00109-1
Qi Liu, Nan Zuo, Xinghan Li, Yongqiang Deng, Lanlan Wei, Lin Ma
{"title":"Novel insights into DNA damage repair defects in HPV-positive head and neck squamous cell carcinoma: from the molecular basis to therapeutic opportunities","authors":"Qi Liu, Nan Zuo, Xinghan Li, Yongqiang Deng, Lanlan Wei, Lin Ma","doi":"10.1007/s42764-023-00109-1","DOIUrl":"https://doi.org/10.1007/s42764-023-00109-1","url":null,"abstract":"","PeriodicalId":73144,"journal":{"name":"Genome instability & disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136063683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信