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Practical Considerations for Machine Learning-Enabled Discoveries in Spatial Transcriptomics 空间转录组学中机器学习发现的实用考虑因素
GEN biotechnology Pub Date : 2024-06-13 DOI: 10.1089/genbio.2023.0050
Alex J. Lee, Robert Cahill, Reza Abbasi-Asl
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引用次数: 0
Yeasty HAC Does the Trick 酵母菌 HAC 起作用
GEN biotechnology Pub Date : 2024-06-13 DOI: 10.1089/genbio.2024.0026
Joshua S James, Alba Ballerini, Yizhi Cai
{"title":"Yeasty HAC Does the Trick","authors":"Joshua S James, Alba Ballerini, Yizhi Cai","doi":"10.1089/genbio.2024.0026","DOIUrl":"https://doi.org/10.1089/genbio.2024.0026","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141348462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Massive Attack: Can Biotechnology Turn a Bonanza of Data into a Boon? 大举进攻：生物技术能否将大量数据转化为财富？
GEN biotechnology Pub Date : 2024-06-13 DOI: 10.1089/genbio.2024.0027
Mike May
{"title":"Massive Attack: Can Biotechnology Turn a Bonanza of Data into a Boon?","authors":"Mike May","doi":"10.1089/genbio.2024.0027","DOIUrl":"https://doi.org/10.1089/genbio.2024.0027","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
T-Cell Differentiation from Hematopoietic Progenitor Cells Using 3D Thymic-like Hydrogels 利用三维胸腺样水凝胶从造血祖细胞分化出 T 细胞
GEN biotechnology Pub Date : 2024-06-13 DOI: 10.1089/genbio.2024.0010
Asel Primbetova, Han Hsuan Hsu, Alexander Baker, Ross Jones, Carla Zimmerman, Molly S. Shoichet, Peter W. Zandstra
{"title":"T-Cell Differentiation from Hematopoietic Progenitor Cells Using 3D Thymic-like Hydrogels","authors":"Asel Primbetova, Han Hsuan Hsu, Alexander Baker, Ross Jones, Carla Zimmerman, Molly S. Shoichet, Peter W. Zandstra","doi":"10.1089/genbio.2024.0010","DOIUrl":"https://doi.org/10.1089/genbio.2024.0010","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141347148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deoxycholate-Based Composite Microparticles for Localized Adipocytolysis 用于局部脂肪溶解的脱氧胆酸盐基复合微粒
GEN biotechnology Pub Date : 2024-06-13 DOI: 10.1089/genbio.2024.0017
Daniel Kupor, Michael L. Felder, Hanieh Safari, O. Eniola-Adefeso
{"title":"Deoxycholate-Based Composite Microparticles for Localized Adipocytolysis","authors":"Daniel Kupor, Michael L. Felder, Hanieh Safari, O. Eniola-Adefeso","doi":"10.1089/genbio.2024.0017","DOIUrl":"https://doi.org/10.1089/genbio.2024.0017","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141345392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Bioorthogonal Stimulated Raman Scattering Imaging Uncovers Lipid Metabolic Dynamics in Drosophila Brain During Aging, by Li et al. GEN Biotechnol 2023;2(3):247-261; doi: 10.1089/genbio.2023.0017.correx 更正：生物正交刺激拉曼散射成像揭示果蝇大脑衰老过程中的脂质代谢动态》，作者：Li 等。 GEN Biotechnol 2023；2（3）：247-261；doi：10.1089/genbio.2023.0017.correx
GEN biotechnology Pub Date : 2024-03-25 DOI: 10.1089/genbio.2023.0017.correx
{"title":"Correction to: Bioorthogonal Stimulated Raman Scattering Imaging Uncovers Lipid Metabolic Dynamics in Drosophila Brain During Aging, by Li et al. GEN Biotechnol 2023;2(3):247-261; doi: 10.1089/genbio.2023.0017.correx","authors":"","doi":"10.1089/genbio.2023.0017.correx","DOIUrl":"https://doi.org/10.1089/genbio.2023.0017.correx","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140381664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Addressing Scientific Misconduct: An Interview with Elisabeth Bik, by Bik and Thomas, GEN Biotechnol 2024;3(1):19–22; doi: 10.1089/genbio.2024.29132.ebi 更正：解决科学不端行为：采访伊丽莎白-比克》，作者：比克和托马斯，《GEN Biotechnol 2024》；3（1）：19-22；doi：10.1089/genbio.2024.29132.ebi
GEN biotechnology Pub Date : 2024-03-15 DOI: 10.1089/genbio.2024.29132.ebi.correx
{"title":"Correction to: Addressing Scientific Misconduct: An Interview with Elisabeth Bik, by Bik and Thomas, GEN Biotechnol 2024;3(1):19–22; doi: 10.1089/genbio.2024.29132.ebi","authors":"","doi":"10.1089/genbio.2024.29132.ebi.correx","DOIUrl":"https://doi.org/10.1089/genbio.2024.29132.ebi.correx","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Metabolic Engineering to Enhance Provitamin D3 Accumulation in Edible Tomatoes (DOI: 10.1089/genbio.2023.0015) 更正：通过代谢工程提高食用番茄中维生素 D3 的积累 (DOI: 10.1089/genbio.2023.0015)
GEN biotechnology Pub Date : 2024-02-20 DOI: 10.1089/genbio.2023.0015.correx
{"title":"Correction to: Metabolic Engineering to Enhance Provitamin D3 Accumulation in Edible Tomatoes (DOI: 10.1089/genbio.2023.0015)","authors":"","doi":"10.1089/genbio.2023.0015.correx","DOIUrl":"https://doi.org/10.1089/genbio.2023.0015.correx","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140448474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Fluorescent Sex-Sorting Technique for Insects with the Demonstration in Drosophila melanogaster. 以黑腹果蝇为示范的昆虫荧光性别分类技术。
GEN biotechnology Pub Date : 2024-02-01 Epub Date: 2024-02-15 DOI: 10.1089/genbio.2023.0041
Junru Liu, Danny Rayes, Omar S Akbari
{"title":"A Fluorescent Sex-Sorting Technique for Insects with the Demonstration in <i>Drosophila melanogaster</i>.","authors":"Junru Liu, Danny Rayes, Omar S Akbari","doi":"10.1089/genbio.2023.0041","DOIUrl":"10.1089/genbio.2023.0041","url":null,"abstract":"<p><p>Recent advances in insect genetic engineering offer alternative genetic biocontrol solutions to control populations of pests and disease vectors. While success has been achieved, sex-sorting remains problematic for scaling many genetic biocontrol interventions. Here, we describe the development of a genetically stable sex-sorting technique for female and male selection with a proof of concept in <i>Drosophila melanogaster</i> termed SEPARATOR (Sexing Element Produced by Alternative RNA-splicing of A Transgenic Observable Reporter). This elegant approach utilizes dominantly expressed fluorescent proteins and differentially spliced introns to ensure sex-specific expression. The system has the potential for adaptability to various insect species and application for high-throughput insect sex-sorting.</p>","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10895710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139984733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Physical View of the Origin of Genetic Engineering 基因工程起源的物理学观点
GEN biotechnology Pub Date : 2023-12-07 DOI: 10.1089/genbio.2023.0037
Anna Yakimova, Denis Baranovskii, Sergei A. Ivanov, Peter Shegay, A. D. Kaprin, Ilya D. Klabukov
{"title":"The Physical View of the Origin of Genetic Engineering","authors":"Anna Yakimova, Denis Baranovskii, Sergei A. Ivanov, Peter Shegay, A. D. Kaprin, Ilya D. Klabukov","doi":"10.1089/genbio.2023.0037","DOIUrl":"https://doi.org/10.1089/genbio.2023.0037","url":null,"abstract":"","PeriodicalId":73134,"journal":{"name":"GEN biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138591361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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