Acta chirurgica Scandinavica. Supplementum最新文献

{"title":"Will interventional angiology replace vascular surgery?","authors":"R L Dalman, L M Taylor, J M Porter","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"25-35"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13297403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The practical consequences of research in arteriosclerosis.","authors":"M R Tyrrell,&nbsp;J H Wolfe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite the impressive volume of work that has been undertaken, the successful medical therapy of arteriosclerosis continues to elude us--preventive measures and surgical treatment of its complications persist as the primary modalities of treatment. While research into the fundamental pathophysiology surrounding arteriosclerosis is not complete and our understanding is plagued by the current plethora of confusing and contradictory reports, the cellular mechanisms underlying this process are gradually being clarified. As yet, this basic research has had limited impact for vascular surgical patients, who have benefited more as a result of epidemiological studies. For instance, we are more diligent in looking for occult disease, less ready to operate on obvious lesions, and more persuasive in our attempts to alter the patient's lifestyle--particularly smoking habits.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13347777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standards for the cost-benefit approach to vascular surgery.","authors":"D Bergqvist,&nbsp;S Jendteg,&nbsp;B Lindgren","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"105-10"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13269357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interferons.","authors":"G V Alm","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The interesting and complex biology of the interferon (IFN) system is briefly reviewed. Some encouraging results from the application of IFNs to therapy of human disease, as well as therapeutic problems are also pointed out. It is likely that increased knowledge of the functions of the IFN system will facilitate development of more efficient therapeutic strategies, involving e.g., mobilization of the patient's own ability to produce IFN, new combination therapies and circumvention of side effects such as development of antibodies neutralizing IFNs and autoimmunity.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"549 ","pages":"35-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13613009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunotherapy of tumors with monoclonal antibodies.","authors":"L Lindholm","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"549 ","pages":"46-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13790718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathophysiological mechanisms of thromboembolism.","authors":"B Risberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The first section of this review describes the hemostatic balance as it is regulated at the blood-tissue interface. Endothelial cells have a nonthrombogenic surface during resting conditions. In diseased states, such as trauma or infection, the endothelial cells become perturbated and the anticoagulant activity is transformed into a procoagulant activity. Recent data have demonstrated that endothelial cells have surface receptors and the capacity for initiating coagulation and propagating the coagulation cascade. The second part of this review discusses the role of the fibrinolytic system in thromboembolism. Defects in the system have been found to be pathogenetic factors in postoperative deep vein thrombosis. Several studies have indicated that this surgical sequela does not occur in patients with an active fibrinolytic system. These results suggest that screening patients for fibrinolytic abnormalities may identify those persons at high risk for the development of postoperative deep vein thrombosis.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"550 ","pages":"104-14"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13794259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological response modifiers in treatment of cancer with special reference to GI cancer: present status and future aspects. 1988 Oncology Symposium. Göteborg, Sweden, March 13-17.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"549 ","pages":"1-83"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14064572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The upper gastrointestinal microflora in relation to gastric diseases and gastric surgery.","authors":"S Sjöstedt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The upper gastrointestinal microflora was evaluated in relation to gastric diseases and gastric surgery. Postoperative septic complications and microorganisms found in primary infections were studied in 750 gastric operations. The overall rate of primary infections was 23%. Enterobacteriaceae, enterococci and Bacteroides fragilis were more frequently found in postoperative infections in patients with gastric bleeding or carcinoma. The microbial colonization of the oropharynx, esophagus and stomach was studied in 60 patients. Patients with gastritis, carcinoma and a history of gastric resection harboured more microorganisms in their stomachs than patients with gastric or duodenal ulcers. Patients with gastric carcinoma were colonized with the highest numbers of different microorganisms. The microbial colonization in 23 patients with gastric carcinoma was studied. The tumor was colonized in all patients. Clostridium species were isolated from 57% of the patients. Antibiotic agents used as prophylaxis in gastric cancer surgery should cover both aerobic and anaerobic microorganisms, including B. fragilis. The effect of 400 mg ofloxacin on the microflora in gastric juice was evaluated in 24 patients undergoing gastric surgery. Both the aerobic and anaerobic flora were suppressed on the day of surgery, but increased in number afterwards. There was a significant correlation between gastric pH and the number of microorganisms isolated in the gastric juice. The degree of Campylobacter pylori colonization in relation to other microorganisms on antral mucosal biopsies was investigated in 53 patients with dyspeptic symptoms. Microbial colonization was found in 94% of the patients. Microorganisms other than C. pylori were found irrespective of the diagnoses. C. pylori was with one exception only found in patients with gastritis. No relation between the gastric pH and the microbial colonization of the mucosa was found. The relationship between hospital and catchment area utilization of antimicrobial agents and antibiotic susceptibility of isolated bacteria in primary infections after gastric operations were studied. Over 80% of the antibiotics were used in the catchment area. No major problems with bacterial resistance to antimicrobial agents were found. The pattern of bacterial resistance reflected the use of antimicrobial agents in the catchment area more than that in the hospital.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"551 ","pages":"1-57"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13880580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of soft tissue sarcomas with interferon with special reference to general features of interferon therapy.","authors":"P Gröhn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"549 ","pages":"50-1"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13613010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on hybridoma technology in radioimmunodetection and therapy.","authors":"T Stigbrand","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"549 ","pages":"40-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13790717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}