Acta chirurgica Scandinavica. Supplementum最新文献

{"title":"The limits of vascular interventional radiology.","authors":"I Enge","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"21-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13297402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet-induced thermogenesis. An experimental study in healthy and obese individuals.","authors":"A Thörne","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Diet-induced thermogenesis (DIT) denotes the increase in energy expenditure that occurs in response to food ingestion. The purpose of the present study was to examine the possible influence of age, training state and sympatho-adrenal activity on the early phase of DIT in healthy individuals and further to study whether the magnitude of DIT is reduced in human obesity and, if so, to what extent DIT is influenced by weight reduction induced by surgical treatment, i.e. gastric banding or vertical banded gastroplasty. In addition, the effect of an artificial abdominal insulation on the DIT reaction was examined in healthy subjects in order to find out if the spontaneously enhanced thermal insulation of the body in obese individuals may be accompanied by a reduced DIT. The subjects were studied in the basal state and during 2-3 hours after a mixed meal. The energy expenditure was determined by indirect calorimetry. Blood temperature and blood flow in the hepatic vein were measured and splanchnic oxygen uptake and blood-drained heat from the splanchnic region were calculated. The meal was in liquid form, consisting of 17% kJ protein, 28% kJ lipids and 55% kJ carbohydrates, corresponding to either 60% of the individually measured 24-h resting energy expenditure or to 40% of the individually predicted basal metabolic rate. DIT was expressed as the average increase in energy expenditure above the basal level (means +/- SEM). After a 60% meal it was less (21 +/- 3%, P less than 0.01) in 8 elderly (70 +/- 1 years) and 7 middle-aged (51 +/- 3 yrs) individuals (24 +/- 2%, P less than 0.05) than in 10 young (27 +/- 1 yrs) men (29 +/- 2%). Its magnitude was similar (n.s.) in 7 well-trained men with a higher (58 +/- 2 ml/min/kg BW) maximal oxygen uptake (25 +/- 2%) and 7 sedentary individuals with a lower (39 +/- 2 ml/min/kg BW) aerobic capacity (29 +/- 2%). An intravenous pharmacological inhibition of the beta-adrenergic receptor function failed to influence the DIT in 10 men, irrespective of whether the beta-blockade was instituted by a selective-beta-1 antagonist (atenolol) or a non-selective blocker (propranolol). The DIT was 29 +/- 1% with and 29 +/- 2% (n.s.) without a beta-blockade and it was 29% in 2 subjects after 1 week of oral propranolol medication.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"558 ","pages":"6-59"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13331270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in vascular surgery 1990. International symposium. May 27-29, 1990, Oslo, Norway. Proceedings.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"1-256"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13516391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacologic profile of a low molecular weight heparin (enoxaparin): experimental and clinical validation of the prophylactic antithrombotic effects.","authors":"J Fareed,&nbsp;J M Walenga,&nbsp;M Lassen,&nbsp;L Borris,&nbsp;D Hoppensteadt,&nbsp;R Murphy,&nbsp;A Ahsan,&nbsp;S Weber,&nbsp;L N Jorgensen,&nbsp;O Hauch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some 10 low molecular weight heparin products are currently available for commercial use. Enoxaparin and fraxiparin appear to be the most developed low molecular weight heparins. Many well-designed clinical trials have been carried out for different clinical indications with both of these products. As shown in both experimental and clinical settings, the prophylactic antithrombotic efficacy of enoxaparin is distinct from other low molecular weight heparins. Enoxaparin has provided consistently impressive clinical results. Moreover, at comparable dosages, other products have exhibited safety/efficacy profiles different from that of enoxaparin. The clinical performance of each low molecular weight heparin is characteristic of only that particular agent. Besides the commercially available low molecular weight heparin preparations, some 14 other agents are under development at this time. Although each product has similar basic characteristics, their biological actions should be studied carefully. Apart from differences in the physicochemical properties, the pharmacologic actions of these agents may differ significantly. Only results from valid clinical trials will show similarities or differences between the low molecular weight heparins. Other manufacturers should follow the lead of enoxaparin and conduct their own clinical trials on each of their products.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"556 ","pages":"75-90"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13122156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacokinetics of low molecular weight heparins.","authors":"L Bara,&nbsp;M Samama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>When measured in terms of biological activities (using only markers of molecules with affinity for antithrombin III), the pharmacokinetics of low molecular weight heparins are clearly different from those of unfractionated heparin after intravenous and subcutaneous injections. The plasmatic anti-Factor Xa activity half-life, whatever the injected dose of the different low molecular weight heparins, is about two to four times longer than for unfractionated heparin while anti-Factor IIa plasmatic half-life is only slightly longer for enoxaparin than for unfractionated heparin. Preferential endothelial cell binding of high molecular weight heparin chains that possess greater anti-Factor IIa activity may partly explain these differences. When measured in terms of radioactive markers of molecules with either high or low affinity for antithrombin III, in native form or degraded after endocytosis by endothelial cells, using 99 m technetium labelled heparins in human volunteers, the pharmacokinetics in blood, urine and organs are similar whatever the heparin used (enoxaparin or unfractionated heparin). The radioactive half-life was longer than that of the biological activity. These results suggest that enoxaparin binds less than unfractionated heparin to proteins other than antithrombin III and that enoxaparin is partly eliminated in urine as active metabolites.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"556 ","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13120761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Which is the best vascular prosthesis below the inguinal ligament?","authors":"D Charlesworth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prostheses made of P.T.F.E give reasonable results when used as femoropopliteal bypass below the inguinal ligament and above the knee joint in patients with good \"run-off\". Human umbilical vein will probably give similar results but with reservations about its degradability. A compliant tube made from a non biodegradable stable polymer and which has a non thrombogenic internal surface seems to offer the most likely improvement.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"49-50"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13297404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis, treatment and prevention of aorto-enteric fistulas.","authors":"J Goldstone,&nbsp;C C Cunningham","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"165-72"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13347768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal reconstruction of the renal arteries.","authors":"S E Bergentz,&nbsp;D Bergqvist,&nbsp;H Weibull","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"227-35"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13347773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can prosthetic graft infection be avoided? If not, how do we treat it?","authors":"R A Yeager,&nbsp;G L Moneta,&nbsp;L M Taylor,&nbsp;D B McConnell,&nbsp;J M Porter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Most arterial prosthetic graft infections can be prevented although a few will inevitably still occur. Maintaining a high index of suspicion for graft infection permits prompt diagnosis which provides the opportunity for early surgical management and improved potential for a good result. Aortic graft infection is best managed with extra-anatomical prosthetic bypass through clean tissue followed by graft excision. Results with this surgical approach are improving. Recently, authors advocating in situ grafting for graft enteric fistula as well as others recommending nonresectional therapy for localized prosthetic graft infections, have obtained encouraging results comparable to the best series of more standard excisional therapy. Because prosthetic graft infection remains a difficult surgical problem, any potentially useful management innovations warrant serious consideration and analysis with extended follow-up.</p>","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"155-63"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13348491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical versus medical treatment for symptomatic carotid atherosclerosis.","authors":"C Warlow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7309,"journal":{"name":"Acta chirurgica Scandinavica. Supplementum","volume":"555 ","pages":"223-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13517026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}