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Data Driven vigiPoint Identification Study of Adverse Event Reporting Patterns for Zimbabwe Reports in VigiBase WHO Global Database of Individual Case Safety Reports for Medicines and Vaccines 世卫组织全球药品和疫苗个案安全报告数据库中津巴布韦报告的不良事件报告模式的数据驱动的vigiPoint识别研究
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.121
Priscilla P.M. Nyambayo, Michael S. Gold, Ushma C. Mehta
{"title":"Data Driven vigiPoint Identification Study of Adverse Event Reporting Patterns for Zimbabwe Reports in VigiBase WHO Global Database of Individual Case Safety Reports for Medicines and Vaccines","authors":"Priscilla P.M. Nyambayo, Michael S. Gold, Ushma C. Mehta","doi":"10.26502/fjhs.121","DOIUrl":"https://doi.org/10.26502/fjhs.121","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Biochemical Parameters in COVID-19 and non-COVID-19 Individuals in Gandaki Province, Nepal 尼泊尔甘达基省COVID-19与非COVID-19人群生化指标比较
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.122
Anusha Thapa, Raksha Malla, Rebika Koirala, Sanjeeb Shrestha, Nischal Chimal, Sundar Adhikari, A. Nagila
{"title":"Comparison of Biochemical Parameters in COVID-19 and non-COVID-19 Individuals in Gandaki Province, Nepal","authors":"Anusha Thapa, Raksha Malla, Rebika Koirala, Sanjeeb Shrestha, Nischal Chimal, Sundar Adhikari, A. Nagila","doi":"10.26502/fjhs.122","DOIUrl":"https://doi.org/10.26502/fjhs.122","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Support of Patients Admitted with COVID-19 at Public Hospitals in South Africa by the Family Members 家庭成员对南非公立医院收治的COVID-19患者的支持
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.092
Lu Tr, Malwela T, Ndou Nd, Ramathuba Du, Maputle Ms, Mbedzi T
{"title":"Support of Patients Admitted with COVID-19 at Public Hospitals in South Africa by the Family Members","authors":"Lu Tr, Malwela T, Ndou Nd, Ramathuba Du, Maputle Ms, Mbedzi T","doi":"10.26502/fjhs.092","DOIUrl":"https://doi.org/10.26502/fjhs.092","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic Dermatofibrosarcoma Protuberans in a Young African Lady: A Case Report 非洲年轻女性转移性皮肤纤维肉瘤隆突1例报告
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.146
Motsepe TA, Maritz SM
{"title":"Metastatic Dermatofibrosarcoma Protuberans in a Young African Lady: A Case Report","authors":"Motsepe TA, Maritz SM","doi":"10.26502/fjhs.146","DOIUrl":"https://doi.org/10.26502/fjhs.146","url":null,"abstract":"Dermatofibrosarcoma protuberans (DFSP) is a rare tumour that originates from the dermal fibroblasts. It is often a benign lesion with a low metastatic potential. However, if left untreated, it can become locally aggressive and infiltrate surrounding fascia, muscles and bones. Distant metastases, though uncommon, are usually to the lungs with lymph node involvement being extremely rare. Below is a case of a young African lady who at presentation had a locally advanced DFSP with extensive metastases to distant lymph nodes and the lungs.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135507262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributing Factors to The Awareness of Health Risks of Geophagy Among Pregnant Women in Lubumbashi 卢本巴希孕妇对食土危害认识的影响因素
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.133
Cham LC, Kayeme Z, Bokanya I, Tambwe MA, Bito V, Kakoma SZ
{"title":"Contributing Factors to The Awareness of Health Risks of Geophagy Among Pregnant Women in Lubumbashi","authors":"Cham LC, Kayeme Z, Bokanya I, Tambwe MA, Bito V, Kakoma SZ","doi":"10.26502/fjhs.133","DOIUrl":"https://doi.org/10.26502/fjhs.133","url":null,"abstract":"Geophagy is widely practiced during pregnancy especially in Africa. In Lubumbashi geophagic material contains high levels of toxic metallic elements next to the eggs, larvae, or adult species of the geohelminths and micro toxins. Despite the health risks uncounted, pregnant women still consume clay. Whether pregnant geophagists are aware of the risks-related to geophagia is unknown. A case- control study of 104 geophagists and 107 no geophagists pregnant women was conducted from September 1st, 2022, to February 28th, 2023The pregnant women consecutively enlisted were attending the prenatal care in four medical institutions in Lubumbashi and completed an interview-based questionnaire. 51.7% of the study population were not aware of the health risks of geophagia and consumed large amounts of clay during the early stages of the pregnancy. Identified health risks related to geophagy were mainly helminthic infestation and anemia. The degree of awareness is related to the level of women education and societal/marital status. Our results demonstrate that despite the identified related health risks and the awareness of them, geophagia remains common practice during pregnancy in Lubumbashi. A holistic prevention approach should be implemented to reduce the consequences of geophagy among pregnant women.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135651090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
(-)-Agelastatin A is a Potent Modulator of Osteopontin Expression in Normal and Dystrophic Canine Myoblasts (-)- agelastatin A是正常和营养不良犬成肌细胞中骨桥蛋白表达的有效调节剂
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.143
Madison Feng, Sara Mata López, Peter P. Nghiem
{"title":"(-)-Agelastatin A is a Potent Modulator of Osteopontin Expression in Normal and Dystrophic Canine Myoblasts","authors":"Madison Feng, Sara Mata López, Peter P. Nghiem","doi":"10.26502/fjhs.143","DOIUrl":"https://doi.org/10.26502/fjhs.143","url":null,"abstract":"(-)-Agelastatin A [(-)-AA] is a naturally occurring alkaloid of marine sponge origin that is a potent modulator of osteopontin. The latter is a multifunctional cytokine expressed in many types of cells and is involved with several important cellular processes, including adhesion, proliferation, immune response stimulation, and so on. As such, modulating OPN could be of therapeutic benefit for various diseases. On that note, (-)-AA has been shown to reduce OPN in xenografted human tumors in nude mice. Additionally, an OPN genotype was associated loss of ambulation in Duchenne muscular dystrophy (DMD) boys and its expression associated with pathology. In this study, we analyzed OPN expression in normal and canine DMD stem cells (myoblasts) after AA treatment. When suspended in 1,2-propanediol (3-deoxy-DL-glycerol), (-)-AA elicited a dose-dependent decrease in OPN mRNA expression in canine DMD myoblasts at doses ranging from 0.01nM – 30nM. There was also a dose-dependent cell detachment after 24 hours of AA treatment with concentrations of 10nM and greater. Further studies are warranted to determine if (-)-AAis safe and can provide therapeutic benefit in animal models of DMD.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatitis E Virus (HEV) Seroprevalences in Pigs and among pork Butchers in two regions of Northern Togo 多哥北部两个地区猪群和肉贩戊型肝炎病毒(HEV)血清流行情况
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.116
Komi V-M. Setondji, K. A. Traore, Jean B. Ouoba, E. Taale, Bruno L. Ouoba, Bissah K. Nyakou, Judith Akpandja, Nicolas Kpanegue, P. Roques, Simplice D. Karou, N. Barro
{"title":"Hepatitis E Virus (HEV) Seroprevalences in Pigs and among pork Butchers in two regions of Northern Togo","authors":"Komi V-M. Setondji, K. A. Traore, Jean B. Ouoba, E. Taale, Bruno L. Ouoba, Bissah K. Nyakou, Judith Akpandja, Nicolas Kpanegue, P. Roques, Simplice D. Karou, N. Barro","doi":"10.26502/fjhs.116","DOIUrl":"https://doi.org/10.26502/fjhs.116","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Cancer in an Elderly Man with Cervical Radiculopathy: A Case Report 老年男性颈神经根病罕见癌1例报告
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.097
Sunder Sham, H. Hosseini, Beatriz Caraballo Bordon, D. Morrar, A. Bendari, R. Al-Refai, M. Abdelwahed, M. Harshan
{"title":"A Rare Cancer in an Elderly Man with Cervical Radiculopathy: A Case Report","authors":"Sunder Sham, H. Hosseini, Beatriz Caraballo Bordon, D. Morrar, A. Bendari, R. Al-Refai, M. Abdelwahed, M. Harshan","doi":"10.26502/fjhs.097","DOIUrl":"https://doi.org/10.26502/fjhs.097","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Profile of Patients of Acute Rheumatic Fever in a Specialized Center 某专科医院急性风湿热患者临床分析
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.131
Md. Saidul Alam, Mohammad Abdul Hye, Shuperna Ahmed, Mohammad Aminul Islam, Md. Arifur Rahman, Shamsi Sumaiya Ashique, Lohani Md Tajul Islam, Mohammad Jobayer
{"title":"Clinical Profile of Patients of Acute Rheumatic Fever in a Specialized Center","authors":"Md. Saidul Alam, Mohammad Abdul Hye, Shuperna Ahmed, Mohammad Aminul Islam, Md. Arifur Rahman, Shamsi Sumaiya Ashique, Lohani Md Tajul Islam, Mohammad Jobayer","doi":"10.26502/fjhs.131","DOIUrl":"https://doi.org/10.26502/fjhs.131","url":null,"abstract":"Background: Acute rheumatic fever (ARF) is an important preventable health problem in developing countries. Early detection of clinical manifestations leads to better management of the disease. The study was designed to analyze the clinical characteristics of patients of ARF in a specialized center.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135441123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcriptome and SARS-CoV-2 Biological Network Directed Analysis for Better Therapeutic Development 转录组和SARS-CoV-2生物网络定向分析有助于更好的治疗开发
Fortune journal of health sciences Pub Date : 2023-01-01 DOI: 10.26502/fjhs.142
Om Prakash Sharma, Ruchika Sharma, Vinay Chandil
{"title":"Transcriptome and SARS-CoV-2 Biological Network Directed Analysis for Better Therapeutic Development","authors":"Om Prakash Sharma, Ruchika Sharma, Vinay Chandil","doi":"10.26502/fjhs.142","DOIUrl":"https://doi.org/10.26502/fjhs.142","url":null,"abstract":"Background: It has been almost 3.5 years since the first SARS-CoV-2 virus was first reported in the city of Wuhan. While the FDA has approved a number of drugs for Covid-19, the presence of the disease and its symptoms underscores the continued demand for an improved treatment option to effectively address the existing challenges. In this study, our goal is to identify pivotal protein targets, strongly correlated across lung, blood, and peripheral blood mononuclear cell (PBMC) transcriptomics datasets, to suggest promising targets for comprehensive therapeutic development across multiple tissues.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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