Foregut (Thousand Oaks, Calif.)最新文献_第8页

Topic: Esophagus Benign-GERD, Achalasia, Motility Abstract ID: 50 Esophageal Functional Testing in Lung Transplant Recipients With Esophagogastric Junction Outflow Disorders 题目:食管良性-胃反流，贲门失弛缓，运动[ID: 50]肺移植术后食管胃交界流出障碍患者的食管功能检测

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-09-01 DOI: 10.1177/26345161231189160

Andrés Latorre-Rodríguez, Madison Golla, Ross Bremner, Sumeet Mittal

引用次数: 0

10 Critical Steps of Hiatal Hernia Repair and Anti-Reflux Surgery: An Expert Consensus and Literature Review 裂孔疝修补和抗反流手术的10个关键步骤:专家共识和文献综述

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-08-02 DOI: 10.1177/26345161231190069

Madison Tyle, Madison Noom, Alec Bigness, A. Saad, R. Acho, Abdul-Rahman F. Diab, J. Sujka, C. DuCoin

{"title":"10 Critical Steps of Hiatal Hernia Repair and Anti-Reflux Surgery: An Expert Consensus and Literature Review","authors":"Madison Tyle, Madison Noom, Alec Bigness, A. Saad, R. Acho, Abdul-Rahman F. Diab, J. Sujka, C. DuCoin","doi":"10.1177/26345161231190069","DOIUrl":"https://doi.org/10.1177/26345161231190069","url":null,"abstract":"Background: There is significant variability in the treatment of hiatal hernias, which has led to various perspectives regarding the proper manner of dissection, repair, and reconstruction. We sought to evaluate and analyze expert opinions, survey data, and the literature to define the critical steps in hiatal hernia repair. Methods: A focus group (focus) of expert foregut surgeons defined and agreed upon a sequence of critical steps of a hiatal hernia repair. Using the data from the focus group, an anonymous survey was compiled and distributed to members of the American Foregut Society (AFS). The survey data (survey) was then compared to the focus for agreement. The compiled focus and survey data was interpreted as expert recommendation (expert). A literature review (literature) was then conducted and compared to expert data for agreement and evaluation of discordance. This was used to define the critical steps of hiatal hernia repair. Results: Of the 10 identified critical steps, there was agreement on 9 of 10 steps between focus and survey. The 1 step with discordance was supported by the literature. Conclusions: Ten critical steps have been identified to help produce a succinct and reproducible approach to hiatal hernia repair. It is believed that adherence to these steps will allow the surgeon to achieve a safe and successful hiatal repair.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"108 1","pages":"270 - 281"},"PeriodicalIF":0.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66050916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patterns of Esophageal Motility and Bolus Transit in Children With Repaired Esophageal Atresia 食管闭锁修复后儿童食管运动模式及丸输送

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-08-01 DOI: 10.1177/26345161231190569

C. Bingham, E. White, M. Papadopoulos, M. Mutalib

{"title":"Patterns of Esophageal Motility and Bolus Transit in Children With Repaired Esophageal Atresia","authors":"C. Bingham, E. White, M. Papadopoulos, M. Mutalib","doi":"10.1177/26345161231190569","DOIUrl":"https://doi.org/10.1177/26345161231190569","url":null,"abstract":"Esophageal dysmotility is common after esophageal atresia (EA) repair. Esophageal manometry (HRM) is the gold standard to investigate motility. We aim to characterize esophageal dysmotility and bolus transit for liquid and solids in children with repaired EA. Retrospective analysis of HRM from children with repaired EA. Five liquid and 5 solid swallows per child were assessed for the standard manometric measurement and peristalsis pattern. Impedance tracings were used to assess bolus transit. Ninety measurements were assessed from 9 patients, 44% Females. Mean age was 10.5 (±4.6) years. All children had dysphagia and anastomotic strictures were excluded. None of the children had intact peristalsis, 44.4% of the liquid swallows were failed, 33.3% fragmented and 22.2% ineffective. 44.4% of the solid swallows were failed, 44.4% fragmented and 11.1% ineffective. 33.3% had incomplete bolus transit in the whole esophagus, 44.4% in the upper and 11% in the lower esophagus. Mean peristalsis break for liquid was 7 cm (±2.1) and for solid was 5.9 cm (±3.2) P .025. Impaired esophageal motility is universal post EA repair. Failed and ineffective peristalsis predominate with incomplete bolus transit and large peristalsis breaks after liquid and solid swallows. HRM can provide clinical guidance, diagnostic and prognostic information post EA repair.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49218204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophageal Dilation: Pearls and Pitfalls 食管扩张:珍珠和陷阱

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-08-01 DOI: 10.1177/26345161231189687

K. DeVault

引用次数: 0

Ineffective Esophageal Motility: Discard or Discover? 无效的食管运动:抛弃还是发现?

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-07-28 DOI: 10.1177/26345161231188345

Anand S. Jain

引用次数: 0

Survival Trends and Profiling of Gastric Mixed Adenoneuroendocrine Carcinoma (gMANEC) in the Current Era 当代胃混合型腺神经内分泌癌（gMANEC）的生存趋势和特征

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-07-18 DOI: 10.1177/26345161231188677

Shreya Gupta, James D. Mcdonald, A. J. Rossi, Jonathan M. Hernandez, Jeremy L. Davis, A. Blakely

{"title":"Survival Trends and Profiling of Gastric Mixed Adenoneuroendocrine Carcinoma (gMANEC) in the Current Era","authors":"Shreya Gupta, James D. Mcdonald, A. J. Rossi, Jonathan M. Hernandez, Jeremy L. Davis, A. Blakely","doi":"10.1177/26345161231188677","DOIUrl":"https://doi.org/10.1177/26345161231188677","url":null,"abstract":"Gastric mixed adenoneuroendocrine carcinoma (gMANEC) is a histopathologic diagnosis with at least 30% each of exocrine and endocrine components. Although prognosis is thought to be driven by the relative exocrine or endocrine dominance, gMANEC has been clinically treated as gastric adenocarcinoma (gAC). The overall survival of gMANEC as compared to gastric neuroendocrine carcinoma (gNEC) or gAC remains undefined. Using the National Cancer Database, patients with gastric tumors were queried from 2004 to 2016 for gMANEC, gNEC, and gAC histologies. Demographic and clinicopathologic features were recorded. Univariate and multivariate Cox proportional hazards analyses were performed to delineate factors associated with overall survival (OS). Overall, 404 patients diagnosed with gMANEC were identified. Patients had a median age 68 years, were majority male, and predominantly Caucasian. Gastric MANEC was more frequently poorly differentiated (73%vs 52% (gAC) vs 20% (gNEC), P < .001) with lymphovascular invasion (57%vs 38%vs 27%, P < .001) and lymph node involvement (59%vs 49%vs 36%, P < .001); these factors were associated with worse OS on univariable analysis. Finally, tumors >5 cm and lymph node involvement were independent predictors of worse survival. The median OS of patients with gMANEC was 41.5 months. Gastric MANEC and gAC have a similarly dismal prognosis and thus should be continued to treat like gAC. Pathologic nodal metastasis, tumor size and grade are useful prognostic factors.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46997543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of the SARS-CoV-2 Pandemic on Treatment Pathways and Outcomes of Esophagogastric Cancer: A Pre- Versus Post-Pandemic Comparison of International Prospective Cohort Data SARS-CoV-2大流行对食管胃癌治疗途径和结局的影响:国际前瞻性队列数据的大流行前后比较

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-07-17 DOI: 10.1177/26345161231175981

E. Griffiths, S. Kamarajah

{"title":"Impact of the SARS-CoV-2 Pandemic on Treatment Pathways and Outcomes of Esophagogastric Cancer: A Pre- Versus Post-Pandemic Comparison of International Prospective Cohort Data","authors":"E. Griffiths, S. Kamarajah","doi":"10.1177/26345161231175981","DOIUrl":"https://doi.org/10.1177/26345161231175981","url":null,"abstract":"Introduction: This study aimed to characterize the outcomes of esophagogastric (OG) cancer patients and compare perioperative outcomes with pre-pandemic data. Methods: Three international prospective cohort studies were included in this analysis. First, COVIDSurg-Cancer (n = 1999) included patients with an OG cancer planned for surgery from the start of the pandemic up to 14th April 2020 with follow-up until 31st August 2020. Treatment pathways and outcomes were compared against patients undergoing treatment for OG cancers before the pandemic, Oesophagogastric Anastomosis Audit (OGAA, n = 2246) and GlobalSurg 3 (n = 1256) study. The surgical composite outcome was defined as in patients achieving margin negative resection, resectability and no postoperative mortality. Results: This study included 1999 patients during the COVID-19 pandemic, of which 32.4% had a change from standard pre-pandemic management. Patients with delay to surgery had significantly higher rates of no surgery (24.7%vs 7.5%, P < .001) and less likely to have achieve a composite outcome (57.8%vs 73.4%, P < .001) than those without any delay in surgery. There was no significant difference in 30-day mortality (3.5% vs 3.4%; OR: 0.98, CI95%: 0.69-1.37) or anastomotic leak rate (10.9% vs 10.2%%; OR: 1.11, CI95%: 0.90-1.37) but higher reoperation rates (13.6% vs 10.4%; OR: 1.59, CI95%: 1.30-1.92) in patients between pre-pandemic and pandemic cohorts. Conclusion: The pandemic appears to have led to widespread changes in management pathways affecting one-third of patients. Developing elective surgical pathways resilient to periods of system “stress” are key to minimizing future harm from treatment delay for OG cancer patients.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90313877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and Outcomes of Bariatric Surgery in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis 炎症性肠病患者减肥手术的安全性和结果:系统回顾和荟萃分析

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-07-12 DOI: 10.1177/26345161231185780

Hillary Wilson, K. Verhoeff, J. Dang, J. Kung, N. Switzer, D. Birch, K. Madsen, S. Karmali, V. Mocanu

{"title":"Safety and Outcomes of Bariatric Surgery in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis","authors":"Hillary Wilson, K. Verhoeff, J. Dang, J. Kung, N. Switzer, D. Birch, K. Madsen, S. Karmali, V. Mocanu","doi":"10.1177/26345161231185780","DOIUrl":"https://doi.org/10.1177/26345161231185780","url":null,"abstract":"The need for surgical management of severe obesity in the context of inflammatory bowel disease (IBD) is becoming an increasingly common clinical scenario, yet has been met with significant reservation due to the paucity of current data from which to inform evidence-based clinical decision making. The aim of our study was to perform a systematic review to characterize and evaluate the safety and efficacy of bariatric surgery in IBD patients. A medical librarian developed and executed comprehensive searches on November 2, 2021. The population of interest was adult subjects (>18 years) diagnosed with inflammatory bowel disease (IBD) undergoing any type of bariatric surgery. Meta-analysis was used to evaluate outcomes using RevMan 5.4.1. A total of 330 687 patients were identified within the 11 studies included. Within all included studies there were 1595 patients with IBD. Patients had a mean weighted age of 46.0, with a female predominance (n = 1287, 80.7%). The mean duration of follow up was 39.7 months. Metabolic and anthropometric outcomes were only reported in noncomparative studies evaluating only patients with IBD, limiting the ability to complete meta-analysis. Meta-analysis revealed that IBD was associated with increased rates of postoperative complications (RR 2.14; 95% CI 1.87-2.44; P < .00001) in comparison to controls without IBD. While bariatric surgery presents an effective weight loss option for patients with IBD, these patients are associated with higher rates of postoperative complications. This work highlights the need to better delineate the effect of bariatric procedures for patients with IBD with respect to both metabolic and IBD-related outcomes.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47529241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potassium-Competitive Acid Blockers for the Treatment of Gastroesophageal Reflux Disease 钾竞争性酸阻滞剂治疗胃食管反流病

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-07-08 DOI: 10.1177/26345161231181357

J. Kothadia, C. Howden

引用次数: 0

Abdominal Wall Hernias in Patients with Hiatal Hernias: Predictors of Association in a Large Cohort of Patients Hiatal疝患者的腹壁疝：一组患者中相关性的预测因素

Foregut (Thousand Oaks, Calif.) Pub Date : 2023-06-22 DOI: 10.1177/26345161231180010

Nisarg Mehta, Sven E. Eriksson, P. Zheng, I. Sarici, A. Zaidi, B. Jobe, S. Ayazi

{"title":"Abdominal Wall Hernias in Patients with Hiatal Hernias: Predictors of Association in a Large Cohort of Patients","authors":"Nisarg Mehta, Sven E. Eriksson, P. Zheng, I. Sarici, A. Zaidi, B. Jobe, S. Ayazi","doi":"10.1177/26345161231180010","DOIUrl":"https://doi.org/10.1177/26345161231180010","url":null,"abstract":"Hiatal hernia and abdominal wall hernia (AWH) have a common theme of pathogenesis and etiology. This suggests a potential relationship between these 2 types of hernia. However, no large studies have examined such an association. We designed the current study to characterize this association and identify factors associated with this coexistence. A database of patients seen at a large multi-center health network serving 3 states in the mid-Atlantic region of the United States was queried for patients with a documented diagnosis of hiatal hernia (HH) or paraesophageal hernia (PEH). This population was then divided into groups based on whether or not they had a history of another type of AWH (ventral, inguinal/ femoral, umbilical, or incisional hernia). Demographic and clinical data were compared between groups using univariate, followed by multivariable logistic analysis. The final study population consisted of 28 114 patients (66.5% female) with HH/PEH. The prevalence of AWH in this population was 8.2% (n = 2299). Of these 69.1% had only one AWH with the remaining 30.9% having two or more hernias. Multivariable analysis showed male patients with HH/PEH were more likely to have AWH (OR: 1.97; 95% CI: 1.810-2.162, P <0 .0001). The odds of AWH were higher in patients aged 50 to 80 years old compared to younger patients (OR: 1.527; 95% CI: 1.348-1.730, P <0 .0001). Patients with any comorbidity were also more likely to develop AWH (OR: 1.764; 95% CI: 1.566-1.986, P < 0.0001), with obstructive sleep apnea (OSA) being the comorbidity with the highest risk (OR: 1.295; 95% CI: 1.161-1.444, P <0 .0001), followed by obesity (OR: 1.267; 95% CI: 1.156-1.388, P <0 .0001). The prevalence of an AWH in patients with a HH/PEH was 8.2%. Although HH/PEH are more prevalent in females, males with HH/PEH are at higher risk for AWH. Obesity, OSA, tobacco use, hypertension, diabetes, and hypothyroidism are independent risk factors for presence of an AWH in patients with HH/PEH.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49595830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0