{"title":"Screening by the Fantana Law: How a Normal Marshmallow Study May Avoid Manometry.","authors":"John E Pandolfino, Eric D Shah","doi":"10.1177/26345161261447630","DOIUrl":"10.1177/26345161261447630","url":null,"abstract":"","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"6 2","pages":"163-164"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13337328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148439283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment, treatment, and prevention of complications in eosinophilic esophagitis.","authors":"Evan S Dellon","doi":"10.1177/26345161261455806","DOIUrl":"10.1177/26345161261455806","url":null,"abstract":"<p><p>There are multiple potential complications of eosinophilic esophagitis (EoE). These range from symptom-specific to disease-progression related, which result in fibrostenosis. Clinical manifestations of strictures and narrowing are further complicated by esophageal food impaction (EFI) and esophageal perforation, which can be spontaneous or iatrogenic. This life-threatening complication of EoE is rare and risk can be minimized with careful endoscopic technique during procedures to remove food impactions and during esophageal dilation. Complications of progression can be mitigated with effective EoE treatment and structured patient follow-up and monitoring. This paper reviews this spectrum of EoE complications and discusses assessment, management and prevention.</p>","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13313054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric D Shah, Christy M Dunst, Michael M Awad, Amit Patel, Pichamol Jirapinyo, Rita M Knotts, Walter W Chan, C Prakash Gyawali
{"title":"American Foregut Society Education Committee: Development Of The Advanced Foregut Fellowship Program for Gastroenterology Trainees.","authors":"Eric D Shah, Christy M Dunst, Michael M Awad, Amit Patel, Pichamol Jirapinyo, Rita M Knotts, Walter W Chan, C Prakash Gyawali","doi":"10.1177/26345161261434388","DOIUrl":"10.1177/26345161261434388","url":null,"abstract":"<p><strong>Background: </strong>Foregut disorders, including gastroesophageal reflux disease (GERD), esophageal motility disorders, and obesity, represent a significant and growing clinical and economic burden. The evolution of nuanced diagnostics (e.g., impedance planimetry) and advanced endoscopic therapeutics (e.g., per-oral endoscopic myotomy [POEM], transoral incisionless fundoplication, endobariatrics) has created a training gap not addressed by standard gastroenterology or advanced endoscopy fellowships. Specialized expertise in managing these complex foregut disorders is a critical area of clinical need.</p><p><strong>Methods: </strong>The American Foregut Society (AFS) Education Committee developed a core curriculum for a one-year advanced fellowship program focused on foregut disorders. This advanced program is designed for graduates of three-year accredited gastroenterology fellowship training programs. We define a competency-based assessment framework based on domain-specific Entrustable Professional Activities (EPAs) that integrate the six Accreditation Council for Graduate Medical Education (ACGME) Core Competencies.</p><p><strong>Results: </strong>The Advanced GI Foregut Fellowship curriculum is comprised of three domains: esophageal motility; reflux, mucosal disease, and cancer; and, obesity and metabolic disorders. Fellows will be expected to achieve Level 4 (practice-ready) entrustment in at least two of these domains. Each domain features training to independent proficiency in patient evaluation, diagnostic testing, and therapeutic intervention.</p><p><strong>Conclusion: </strong>The AFS-sponsored Advanced GI Foregut Fellowship is proposed as a pilot program to formally train gastroenterologists to lead interdisciplinary foregut centers. We describe the curriculum, a novel GME assessment framework, and a strategy for implementation and evaluation. The pilot program will be used to determine appropriate training threshold volumes required to achieve competence.</p>","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Image Enhanced Endoscopy in Esophageal Squamous Cell Carcinoma","authors":"Shaleen Vasavada, Sharmila Anandasabapathy","doi":"10.1177/26345161231211752","DOIUrl":"https://doi.org/10.1177/26345161231211752","url":null,"abstract":"Esophageal Squamous Cell Carcinoma (ESCC) accounts for a significant portion of esophageal cancer cases worldwide, particularly in high-risk regions like China, Iran, and eastern Africa. It is often diagnosed at advanced stages, leading to poor prognosis and limited treatment options. Image-enhanced endoscopy enables precise visualization of abnormal mucosa, aiding in targeted biopsies for early detection of ESCC and reducing unnecessary sampling. Various techniques have emerged including lugol’s chromoendoscopy, narrow-band imaging, confocal laser endomicroscopy, and high-resolution microendoscopy. This article also discusses advancements in post-processing imaging technology and the novel role of Artificial Intelligence (AI) in improving diagnostic accuracy. While image enhanced endoscopy is promising, challenges such as training, standardization, and long-term validation remain. Implementing image enhanced endoscopy, combined with advancements in AI, has the potential to transform ESCC diagnosis and significantly improve patient outcomes, especially in high-risk populations.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"131 33","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Macmillan, Yianni Protopapadakis, Gary A. Abrams, Madhusudhan Sunkavalli
{"title":"Empiric Esophageal Dilation for the Treatment of Non-Obstructive Dysphagia","authors":"Katherine Macmillan, Yianni Protopapadakis, Gary A. Abrams, Madhusudhan Sunkavalli","doi":"10.1177/26345161231211749","DOIUrl":"https://doi.org/10.1177/26345161231211749","url":null,"abstract":"Background: Non-obstructive dysphagia is a commonly encountered clinical problem. Methods: We retrospectively analyzed a single tertiary hospital system electronic database from January 2021 to October 2021 for patients undergoing EGD with dilation using ICD-10 codes 43248 and 42450. Results: Of the 411 patients meeting inclusion criteria, 75% of these patients had improvement with empiric dilation. The presence of a superficial mucosal tear post dilation was statistically significant. Conclusion: Empiric dilation is a useful tool for patients with non-obstructive dysphagia.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":" 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135290737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Gastroparesis on Medical Therapy for Gastroesophageal Reflux Disease (GERD)","authors":"Alexander Reddy, C. Prakash Gyawali, Amit Patel","doi":"10.1177/26345161231211758","DOIUrl":"https://doi.org/10.1177/26345161231211758","url":null,"abstract":"Symptoms suspicious for gastroesophageal reflux disease (GERD) represent frequent indications for medical presentation, as do symptoms potentially compatible with delayed gastric emptying. In this clinical setting, care must be taken to characterize patient symptoms accurately, and also appropriately evaluate for pathophysiologic processes including visceral hypersensitivity, rumination syndrome, supragastric belching, cannabinoid hyperemesis, and cyclic vomiting syndrome. While proton pump inhibitors (PPI) are the foundation of medical management of GERD, delayed gastric emptying is a downstream factor that can promote gastroesophageal reflux and warrants tailored clinical management. Specifically, patients with refractory symptoms in the setting of GERD and delayed gastric emptying may benefit from personalized adjunct medical therapy with prokinetics.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"61 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135684538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Pagan-Bolivar, Prateek Mathur, Le Yu Naing, Abigail Stocker, Samuel Carson, Mary Fallat, Thomas L. Abell
{"title":"Gastric Electrical Stimulation is an Effective Treatment Modality for Symptoms of GERD in Patients With Gastroparesis and VACTERL Association","authors":"Andrea Pagan-Bolivar, Prateek Mathur, Le Yu Naing, Abigail Stocker, Samuel Carson, Mary Fallat, Thomas L. Abell","doi":"10.1177/26345161231211017","DOIUrl":"https://doi.org/10.1177/26345161231211017","url":null,"abstract":"Patients with VACTERL Association have multiple gastrointestinal comorbidities extending into adulthood. The term VACTERL stands for vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula (TEF) with or without esophageal atresia (EA), renal anomalies, and limb abnormalities. Symptoms of gastroesophageal reflux disease (GERD), such as heartburn and acid regurgitation, are common in this population, and patients with EA have a higher risk. Multiple therapies have been suggested to treat symptoms of GERD in patients with gastroparesis and VACTERL Association, including acid suppression therapy and treating the underlying gastroparesis. If left untreated, patients who had EA can experience severe complications, including erosive esophagitis, Barrett’s esophagus (BE), peptic strictures, esophageal cancer, and decrease in quality of life. We present 2 cases of patients with VACTERL Association with prior EA, gastroparesis and underlying symptoms of GERD that were successfully treated with gastric electrical stimulation (GES).","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"67 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135683731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiology of Esophageal Squamous Cell Carcinoma","authors":"Swathikan Chidambaram, Sheraz Rehan Markar","doi":"10.1177/26345161231201961","DOIUrl":"https://doi.org/10.1177/26345161231201961","url":null,"abstract":"Esophageal squamous cell carcinoma (ESCC) is a leading cause of death worldwide, particularly prevalent in Southern and Eastern Africa, and central Asia. Initial studies identified various factors associated with an increased risk of ESCC, leading to subsequent research investigating the underlying biological mechanisms. This narrative review aims to summarize the role of risk factors in ESCC development and propose future research directions. A systematic literature search was conducted using EMBASE, MEDLINE/PubMed, and CENTRAL databases to identify relevant publications. Included studies updated the epidemiology of ESCC, including the incidence, prevalence and mortality and its variations globally. We reported on socio-demographic impact on these geographic variations. We, then, focused on identifying risk factors associated with ESCC. The identified risk factors were categorized into 5 subcategories: smoking, alcohol, dietary factors, environmental factors and infection. Each subcategory’s risk factors were summarized and explored, providing geographical links for these associations. The review emphasizes the current understanding of several risk factors for ESCC, and specifically makes geographical links, and potential explanations for their associations were explored. However, further research is essential to validate these findings and gain insights into their impact on tumor biology.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":"461 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135013514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}