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Image Enhanced Endoscopy in Esophageal Squamous Cell Carcinoma 影像增强内镜在食管鳞状细胞癌中的应用
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-11-13 DOI: 10.1177/26345161231211752
Shaleen Vasavada, Sharmila Anandasabapathy
{"title":"Image Enhanced Endoscopy in Esophageal Squamous Cell Carcinoma","authors":"Shaleen Vasavada, Sharmila Anandasabapathy","doi":"10.1177/26345161231211752","DOIUrl":"https://doi.org/10.1177/26345161231211752","url":null,"abstract":"Esophageal Squamous Cell Carcinoma (ESCC) accounts for a significant portion of esophageal cancer cases worldwide, particularly in high-risk regions like China, Iran, and eastern Africa. It is often diagnosed at advanced stages, leading to poor prognosis and limited treatment options. Image-enhanced endoscopy enables precise visualization of abnormal mucosa, aiding in targeted biopsies for early detection of ESCC and reducing unnecessary sampling. Various techniques have emerged including lugol’s chromoendoscopy, narrow-band imaging, confocal laser endomicroscopy, and high-resolution microendoscopy. This article also discusses advancements in post-processing imaging technology and the novel role of Artificial Intelligence (AI) in improving diagnostic accuracy. While image enhanced endoscopy is promising, challenges such as training, standardization, and long-term validation remain. Implementing image enhanced endoscopy, combined with advancements in AI, has the potential to transform ESCC diagnosis and significantly improve patient outcomes, especially in high-risk populations.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empiric Esophageal Dilation for the Treatment of Non-Obstructive Dysphagia 经验性食管扩张术治疗非阻塞性吞咽困难
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-11-09 DOI: 10.1177/26345161231211749
Katherine Macmillan, Yianni Protopapadakis, Gary A. Abrams, Madhusudhan Sunkavalli
{"title":"Empiric Esophageal Dilation for the Treatment of Non-Obstructive Dysphagia","authors":"Katherine Macmillan, Yianni Protopapadakis, Gary A. Abrams, Madhusudhan Sunkavalli","doi":"10.1177/26345161231211749","DOIUrl":"https://doi.org/10.1177/26345161231211749","url":null,"abstract":"Background: Non-obstructive dysphagia is a commonly encountered clinical problem. Methods: We retrospectively analyzed a single tertiary hospital system electronic database from January 2021 to October 2021 for patients undergoing EGD with dilation using ICD-10 codes 43248 and 42450. Results: Of the 411 patients meeting inclusion criteria, 75% of these patients had improvement with empiric dilation. The presence of a superficial mucosal tear post dilation was statistically significant. Conclusion: Empiric dilation is a useful tool for patients with non-obstructive dysphagia.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135290737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invited Commentary: Reflux Disease Questionnaire Scoring and Utilization: A Scoping Review 特邀评论:反流疾病问卷评分和使用:范围审查
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-11-06 DOI: 10.1177/26345161231211769
George Malcolm Taylor, Vic Velanovich
{"title":"Invited Commentary: Reflux Disease Questionnaire Scoring and Utilization: A Scoping Review","authors":"George Malcolm Taylor, Vic Velanovich","doi":"10.1177/26345161231211769","DOIUrl":"https://doi.org/10.1177/26345161231211769","url":null,"abstract":"","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135681984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Gastroparesis on Medical Therapy for Gastroesophageal Reflux Disease (GERD) 胃轻瘫对胃食管反流病药物治疗的影响
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-11-06 DOI: 10.1177/26345161231211758
Alexander Reddy, C. Prakash Gyawali, Amit Patel
{"title":"The Impact of Gastroparesis on Medical Therapy for Gastroesophageal Reflux Disease (GERD)","authors":"Alexander Reddy, C. Prakash Gyawali, Amit Patel","doi":"10.1177/26345161231211758","DOIUrl":"https://doi.org/10.1177/26345161231211758","url":null,"abstract":"Symptoms suspicious for gastroesophageal reflux disease (GERD) represent frequent indications for medical presentation, as do symptoms potentially compatible with delayed gastric emptying. In this clinical setting, care must be taken to characterize patient symptoms accurately, and also appropriately evaluate for pathophysiologic processes including visceral hypersensitivity, rumination syndrome, supragastric belching, cannabinoid hyperemesis, and cyclic vomiting syndrome. While proton pump inhibitors (PPI) are the foundation of medical management of GERD, delayed gastric emptying is a downstream factor that can promote gastroesophageal reflux and warrants tailored clinical management. Specifically, patients with refractory symptoms in the setting of GERD and delayed gastric emptying may benefit from personalized adjunct medical therapy with prokinetics.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135684538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastric Electrical Stimulation is an Effective Treatment Modality for Symptoms of GERD in Patients With Gastroparesis and VACTERL Association 胃电刺激是胃轻瘫患者胃反流症状的有效治疗方式
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-11-06 DOI: 10.1177/26345161231211017
Andrea Pagan-Bolivar, Prateek Mathur, Le Yu Naing, Abigail Stocker, Samuel Carson, Mary Fallat, Thomas L. Abell
{"title":"Gastric Electrical Stimulation is an Effective Treatment Modality for Symptoms of GERD in Patients With Gastroparesis and VACTERL Association","authors":"Andrea Pagan-Bolivar, Prateek Mathur, Le Yu Naing, Abigail Stocker, Samuel Carson, Mary Fallat, Thomas L. Abell","doi":"10.1177/26345161231211017","DOIUrl":"https://doi.org/10.1177/26345161231211017","url":null,"abstract":"Patients with VACTERL Association have multiple gastrointestinal comorbidities extending into adulthood. The term VACTERL stands for vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula (TEF) with or without esophageal atresia (EA), renal anomalies, and limb abnormalities. Symptoms of gastroesophageal reflux disease (GERD), such as heartburn and acid regurgitation, are common in this population, and patients with EA have a higher risk. Multiple therapies have been suggested to treat symptoms of GERD in patients with gastroparesis and VACTERL Association, including acid suppression therapy and treating the underlying gastroparesis. If left untreated, patients who had EA can experience severe complications, including erosive esophagitis, Barrett’s esophagus (BE), peptic strictures, esophageal cancer, and decrease in quality of life. We present 2 cases of patients with VACTERL Association with prior EA, gastroparesis and underlying symptoms of GERD that were successfully treated with gastric electrical stimulation (GES).","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135683731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presidential Address 2023: “Just by Showing Up” 2023年总统演讲:“只要出现”
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-11-06 DOI: 10.1177/26345161231211577
Reginald Bell
{"title":"Presidential Address 2023: “Just by Showing Up”","authors":"Reginald Bell","doi":"10.1177/26345161231211577","DOIUrl":"https://doi.org/10.1177/26345161231211577","url":null,"abstract":"","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135681660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of Esophageal Squamous Cell Carcinoma 食管鳞状细胞癌的流行病学研究
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-10-26 DOI: 10.1177/26345161231201961
Swathikan Chidambaram, Sheraz Rehan Markar
{"title":"Epidemiology of Esophageal Squamous Cell Carcinoma","authors":"Swathikan Chidambaram, Sheraz Rehan Markar","doi":"10.1177/26345161231201961","DOIUrl":"https://doi.org/10.1177/26345161231201961","url":null,"abstract":"Esophageal squamous cell carcinoma (ESCC) is a leading cause of death worldwide, particularly prevalent in Southern and Eastern Africa, and central Asia. Initial studies identified various factors associated with an increased risk of ESCC, leading to subsequent research investigating the underlying biological mechanisms. This narrative review aims to summarize the role of risk factors in ESCC development and propose future research directions. A systematic literature search was conducted using EMBASE, MEDLINE/PubMed, and CENTRAL databases to identify relevant publications. Included studies updated the epidemiology of ESCC, including the incidence, prevalence and mortality and its variations globally. We reported on socio-demographic impact on these geographic variations. We, then, focused on identifying risk factors associated with ESCC. The identified risk factors were categorized into 5 subcategories: smoking, alcohol, dietary factors, environmental factors and infection. Each subcategory’s risk factors were summarized and explored, providing geographical links for these associations. The review emphasizes the current understanding of several risk factors for ESCC, and specifically makes geographical links, and potential explanations for their associations were explored. However, further research is essential to validate these findings and gain insights into their impact on tumor biology.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135013514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare Utilization, Costs and Other Outcomes of Peroral Endoscopic Myotomy (POEM) Versus Heller Myotomy in the Inpatient Management of Achalasia in The United States: A 2016 to 2020 Nationwide Study 美国经口内窥镜肌切开术(POEM)与Heller肌切开术在贲门失弛缓症住院治疗中的医疗保健利用率、成本和其他结果:一项2016年至2020年的全国性研究
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-10-06 DOI: 10.1177/26345161231202957
Yassine Kilani, Mohammad Aldiabat, Maryam Mubashir, Saqr Alsakarneh, Ammar Arif Vohra, Yazan Aljabiri, Falak Hamo, Fnu Vikash, Vikash Kumar, Salih Samo
{"title":"Healthcare Utilization, Costs and Other Outcomes of Peroral Endoscopic Myotomy (POEM) Versus Heller Myotomy in the Inpatient Management of Achalasia in The United States: A 2016 to 2020 Nationwide Study","authors":"Yassine Kilani, Mohammad Aldiabat, Maryam Mubashir, Saqr Alsakarneh, Ammar Arif Vohra, Yazan Aljabiri, Falak Hamo, Fnu Vikash, Vikash Kumar, Salih Samo","doi":"10.1177/26345161231202957","DOIUrl":"https://doi.org/10.1177/26345161231202957","url":null,"abstract":"Introduction: Per-Oral Endoscopic Myotomy (POEM) is the recommended first-line treatment for all achalasia subtypes due to its minimally invasive nature. We aim to evaluate the trends of utilization, costs, and outcomes (mortality and complications) of POEM versus Heller Myotomy (HM) in U.S. hospitals. Methods: This is a retrospective study of individuals admitted with a primary diagnosis of achalasia. Data was obtained from Nationwide Inpatient Sample databases from the years 2016 to 2020 using ICD-10 codes. We assessed the therapeutic procedures employed, the trends and outcomes associated with POEM versus HM in terms of hospital utilization, mortality, morbidity, and the baseline characteristics of our study population. Results: A total of 26 880 adult individuals were diagnosed with achalasia. Of these, 11% underwent POEM, while 59% underwent HM. POEM rates increased from 6% to 10% of achalasia admissions, while HM decreased from 49% to 41% during the study period. No significant differences in total hospital charges or length of stay were observed between the 2 procedures. Regarding procedural complications, HM was associated with significantly reduced odds of pneumonia (adjusted Odds Ratio [aOR] = 0.09, 95% CI: 0.02-0.41), pneumoperitoneum (aOR = 0.11, 95% CI: 0.03-0.36), and pneumomediastinum (aOR = 0.21, 95% CI: 0.06-0.68), with no difference in the odds of esophageal perforation (aOR = 1.33, 95% CI: 0.27-6.48) and sepsis (aOR = 2.04, 95% CI: 0.22-18.40). Conclusion: While HM rates are currently declining in the U.S., POEM usage appears to be increasing. Despite being a less invasive measure than HM, POEM remains underutilized in the U.S.","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135350619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technical Considerations in Improving Delayed Gastric Conduit Emptying After Esophagectomy 改善食管切除术后胃导管延迟排空的技术考虑
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-09-29 DOI: 10.1177/26345161231202961
Nathan Alcasid, Jeffrey B. Velotta
{"title":"Technical Considerations in Improving Delayed Gastric Conduit Emptying After Esophagectomy","authors":"Nathan Alcasid, Jeffrey B. Velotta","doi":"10.1177/26345161231202961","DOIUrl":"https://doi.org/10.1177/26345161231202961","url":null,"abstract":"","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135199526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on Medical Therapy for Ineffective Esophageal Motility: A Systematic Review—Surgical Considerations 食道动力不足的药物治疗综述:系统回顾-手术治疗的考虑
Foregut (Thousand Oaks, Calif.) Pub Date : 2023-09-07 DOI: 10.1177/26345161231198623
Roger P. Tatum
{"title":"Commentary on Medical Therapy for Ineffective Esophageal Motility: A Systematic Review—Surgical Considerations","authors":"Roger P. Tatum","doi":"10.1177/26345161231198623","DOIUrl":"https://doi.org/10.1177/26345161231198623","url":null,"abstract":"","PeriodicalId":73049,"journal":{"name":"Foregut (Thousand Oaks, Calif.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45509023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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