Epilepsy research and treatment最新文献_第6页

Epilepsy, antiseizure therapy, and sleep cycle parameters. 癫痫，抗癫痫治疗和睡眠周期参数。

Epilepsy research and treatment Pub Date : 2013-01-01 Epub Date: 2013-08-07 DOI: 10.1155/2013/670682

Vladimir Shvarts, Steve Chung

引用次数: 40

Diagnosis and management of epileptic encephalopathies in children. 儿童癫痫性脑病的诊断和治疗。

Epilepsy research and treatment Pub Date : 2013-01-01 Epub Date: 2013-07-22 DOI: 10.1155/2013/501981

Puneet Jain, Suvasini Sharma, Manjari Tripathi

引用次数: 27

How sleep activates epileptic networks? 睡眠如何激活癫痫网络？

Epilepsy research and treatment Pub Date : 2013-01-01 Epub Date: 2013-09-12 DOI: 10.1155/2013/425697

Peter Halász

{"title":"How sleep activates epileptic networks?","authors":"Peter Halász","doi":"10.1155/2013/425697","DOIUrl":"10.1155/2013/425697","url":null,"abstract":"Background. The relationship between sleep and epilepsy has been long ago studied, and several excellent reviews are available. However, recent development in sleep research, the network concept in epilepsy, and the recognition of high frequency oscillations in epilepsy and more new results may put this matter in a new light. Aim. The review address the multifold interrelationships between sleep and epilepsy networks and with networks of cognitive functions. Material and Methods. The work is a conceptual update of the available clinical data and relevant studies. Results and Conclusions. Studies exploring dynamic microstructure of sleep have found important gating mechanisms for epileptic activation. As a general rule interictal epileptic manifestations seem to be linked to the slow oscillations of sleep and especially to the reactive delta bouts characterized by A1 subtype in the CAP system. Important link between epilepsy and sleep is the interference of epileptiform discharges with the plastic functions in NREM sleep. This is the main reason of cognitive impairment in different forms of early epileptic encephalopathies affecting the brain in a special developmental window. The impairment of cognitive functions via sleep is present especially in epileptic networks involving the thalamocortical system and the hippocampocortical memory encoding system. ","PeriodicalId":72948,"journal":{"name":"Epilepsy research and treatment","volume":" ","pages":"425697"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40263055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical febrile seizures, mesial temporal lobe epilepsy, and dual pathology. 不典型热性癫痫，内侧颞叶癫痫，双重病理。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2012-04-23 DOI: 10.1155/2012/342928

Nathalie T Sanon, Sébastien Desgent, Lionel Carmant

引用次数: 19

Epileptic encephalopathy in children with risk factors for brain damage. 儿童癫痫性脑病的脑损伤危险因素。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2012-07-12 DOI: 10.1155/2012/747565

Josefina Ricardo-Garcell, Thalía Harmony, Eneida Porras-Kattz, Miguel J Colmenero-Batallán, Jesús E Barrera-Reséndiz, Antonio Fernández-Bouzas, Erika Cruz-Rivero

{"title":"Epileptic encephalopathy in children with risk factors for brain damage.","authors":"Josefina Ricardo-Garcell, Thalía Harmony, Eneida Porras-Kattz, Miguel J Colmenero-Batallán, Jesús E Barrera-Reséndiz, Antonio Fernández-Bouzas, Erika Cruz-Rivero","doi":"10.1155/2012/747565","DOIUrl":"https://doi.org/10.1155/2012/747565","url":null,"abstract":"In the study of 887 new born infants with prenatal and perinatal risk factors for brain damage, 11 children with West syndrome that progressed into Lennox-Gastaut syndrome and another 4 children with Lennox-Gastaut syndrome that had not been preceded by West syndrome were found. In this study we present the main findings of these 15 subjects. In all infants multifactor antecedents were detected. The most frequent risk factors were prematurity and severe asphyxia; however placenta disorders, sepsis, and hyperbilirubinemia were also frequent. In all infants MRI direct or secondary features of periventricular leukomalacia were observed. Followup of all infants showed moderate to severe neurodevelopmental delay as well as cerebral palsy. It is concluded that prenatal and perinatal risk factors for brain damage are very important antecedents that should be taken into account to follow up those infants from an early age in order to detect and treat as early as possible an epileptic encephalopathy.","PeriodicalId":72948,"journal":{"name":"Epilepsy research and treatment","volume":" ","pages":"747565"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/747565","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30889199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Epilepsy, mental health disorder, or both? 癫痫、精神健康障碍，还是两者都有?

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2011-12-15 DOI: 10.1155/2012/163731

Vadim Beletsky, Seyed M Mirsattari

引用次数: 52

Anatomy of the temporal lobe. 颞叶解剖。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2012-03-29 DOI: 10.1155/2012/176157

J A Kiernan

{"title":"Anatomy of the temporal lobe.","authors":"J A Kiernan","doi":"10.1155/2012/176157","DOIUrl":"https://doi.org/10.1155/2012/176157","url":null,"abstract":"Only primates have temporal lobes, which are largest in man, accommodating 17% of the cerebral cortex and including areas with auditory, olfactory, vestibular, visual and linguistic functions. The hippocampal formation, on the medial side of the lobe, includes the parahippocampal gyrus, subiculum, hippocampus, dentate gyrus, and associated white matter, notably the fimbria, whose fibres continue into the fornix. The hippocampus is an inrolled gyrus that bulges into the temporal horn of the lateral ventricle. Association fibres connect all parts of the cerebral cortex with the parahippocampal gyrus and subiculum, which in turn project to the dentate gyrus. The largest efferent projection of the subiculum and hippocampus is through the fornix to the hypothalamus. The choroid fissure, alongside the fimbria, separates the temporal lobe from the optic tract, hypothalamus and midbrain. The amygdala comprises several nuclei on the medial aspect of the temporal lobe, mostly anterior the hippocampus and indenting the tip of the temporal horn. The amygdala receives input from the olfactory bulb and from association cortex for other modalities of sensation. Its major projections are to the septal area and prefrontal cortex, mediating emotional responses to sensory stimuli. The temporal lobe contains much subcortical white matter, with such named bundles as the anterior commissure, arcuate fasciculus, inferior longitudinal fasciculus and uncinate fasciculus, and Meyer's loop of the geniculocalcarine tract. This article also reviews arterial supply, venous drainage, and anatomical relations of the temporal lobe to adjacent intracranial and tympanic structures.","PeriodicalId":72948,"journal":{"name":"Epilepsy research and treatment","volume":" ","pages":"176157"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/176157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30866934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 139

A review of the epidemiology of temporal lobe epilepsy. 颞叶癫痫流行病学回顾。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2011-12-29 DOI: 10.1155/2012/630853

Jose F Téllez-Zenteno, Lizbeth Hernández-Ronquillo

引用次数: 0

Déjà experiences in temporal lobe epilepsy. Déjà在颞叶癫痫方面的经验。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2012-03-20 DOI: 10.1155/2012/539567

Nathan A Illman, Chris R Butler, Celine Souchay, Chris J A Moulin

{"title":"Déjà experiences in temporal lobe epilepsy.","authors":"Nathan A Illman, Chris R Butler, Celine Souchay, Chris J A Moulin","doi":"10.1155/2012/539567","DOIUrl":"10.1155/2012/539567","url":null,"abstract":"Historically, déjà vu has been linked to seizure activity in temporal lobe epilepsy, and clinical reports suggest that many patients experience the phenomenon as a manifestation of simple partial seizures. We review studies on déjà vu in epilepsy with reference to recent advances in the understanding of déjà vu from a cognitive and neuropsychological standpoint. We propose a decoupled familiarity hypothesis, whereby déjà vu is produced by an erroneous feeling of familiarity which is not in keeping with current cognitive processing. Our hypothesis converges on a parahippocampal dysfunction as the locus of déjà vu experiences. However, several other temporal lobe structures feature in reports of déjà vu in epilepsy. We suggest that some of the inconsistency in the literature derives from a poor classification of the various types of déjà experiences. We propose déjà vu/déjà vécu as one way of understanding déjà experiences more fully. This distinction is based on current models of memory function, where déjà vu is caused by erroneous familiarity and déjà vécu by erroneous recollection. Priorities for future research and clinical issues are discussed.","PeriodicalId":72948,"journal":{"name":"Epilepsy research and treatment","volume":" ","pages":"539567"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/539567","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30886658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 50

Neuropathology of temporal lobe epilepsy. 颞叶癫痫的神经病理学。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2012-04-12 DOI: 10.1155/2012/624519

Fahd Al Sufiani, Lee Cyn Ang

引用次数: 111