{"title":"Reflections and experiences in conducting a European survey in relation to clinician practices with vascular access devices for systemic anti-cancer therapy","authors":"Caitriona Duggan , Martha Killilea , Veronica McInerney , Onagh O’Grady , Jacqueline Daly , Aoife Lowery","doi":"10.1016/j.enfcle.2025.502248","DOIUrl":"10.1016/j.enfcle.2025.502248","url":null,"abstract":"<div><h3>Background</h3><div>Intravenous infusion is the principal way of providing systemic anti-cancer therapy (SACT) for the vast majority of malignant diseases with approximately one million infusions conducted worldwide each day. A recent scoping review discovered a significant deficit in the literature covering clinical aspects of vascular access device (VAD) selection, insertion, and, in particular, training and education. To answer some of these questions, we are conducting a survey throughout Europe to investigate healthcare professionals' current practices surrounding vascular access devices used for systemic anti-cancer therapy.</div></div><div><h3>Methods</h3><div>This methods paper describes the actions that a research team studying vascular access took to carry out a comprehensive survey across Europe. The purpose of this paper is to share some reflections regarding the survey design. It also covers the steps involved in creating a high-quality questionnaire, the extent, quality, and impact of Public Patient Involvement (PPI) in survey design, the methodologies used to measure the questionnaire's face and content validity, and the experiences gained about stakeholder engagement and dissemination.</div></div><div><h3>Conclusion</h3><div>This paper summarizes some of the findings acquired from integrating and interacting with PPI during different stages of clinical research. It also provides practical tactics for managing a large global team of collaborators, as well as an explanation of the many methodologies used to increase the survey's validity and accuracy.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 4","pages":"Article 502248"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miguel Ángel Rodríguez-Calero , Peter J. Carr , Paulo Santos-Costa , Ian Blanco-Mavillard
{"title":"Infusion sets and vascular access as a strategy to address future challenges in intravenous therapy","authors":"Miguel Ángel Rodríguez-Calero , Peter J. Carr , Paulo Santos-Costa , Ian Blanco-Mavillard","doi":"10.1016/j.enfcle.2025.502217","DOIUrl":"10.1016/j.enfcle.2025.502217","url":null,"abstract":"<div><div>This special article addresses a highly relevant issue in healthcare, where the demand for care and attention has significantly increased, coinciding with a progressively aging population and the prevalence of multiple chronic conditions. These factors pose considerable challenges for contemporary healthcare systems. Vascular access devices, including peripheral intravenous catheters, are widely utilized for intravenous therapy in hospitals; however, they are associated with risks and complications. Nearly 50% of these catheters are removed in an unplanned manner, which exacerbates the problem of catheter-associated bloodstream infections, leading to serious consequences such as increased mortality and higher hospital costs.</div><div>Despite the interventions proposed by governmental organizations aimed at reducing these complications and enhancing healthcare quality, achieving this goal requires comprehensive knowledge and resources. This includes the use of various lancing devices and technologies, highlighting the imperative need for coordinated and collaborative actions by multidisciplinary teams. Moreover, the importance of professional specialization is crucial for transforming work dynamics into effective collaborative practices. In this context, Infusion and Vascular Access Devices (IVADs) have the potential to improve patient health, alleviate the discomfort associated with catheterization, and enhance patient satisfaction. They present a promising solution for optimizing the delivery of intravenous therapy and addressing future challenges in this field.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 4","pages":"Article 502217"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Ferraz-Torres , Maria Elena Sancho-Sena , Amaya Eguillor de la Torre , Laura Cambra Vidart , Maria Belén Suarez-Mier , Maria Ines Corcuera-Martinez
{"title":"Analysis of risk factors associated with phlebitis in peripheral venous catheters. Zero Phlebitis Project","authors":"Marta Ferraz-Torres , Maria Elena Sancho-Sena , Amaya Eguillor de la Torre , Laura Cambra Vidart , Maria Belén Suarez-Mier , Maria Ines Corcuera-Martinez","doi":"10.1016/j.enfcle.2025.502298","DOIUrl":"10.1016/j.enfcle.2025.502298","url":null,"abstract":"<div><h3>Introduction</h3><div>It is necessary to know the rate of phlebitis associated with its use and the risk factors associated with peripheral vascular catheter management that directly influence the presence of phlebitis.</div></div><div><h3>Methodology</h3><div>observational descriptive study, carried out after the implementation of the Zero Phlebitis Project in a large-capacity (>1,000 beds) urban tertiary hospital of reference in Navarra. The implementation of the Zero Phlebitis Project was carried out progressively, incorporating 4 units (2 medical and 2 surgical) per year, ending in February 2023. Subsequently, data collection for the present study began in May 2023.</div></div><div><h3>Results</h3><div>687 catheters were included, 48.3% (332) catheters were implanted in men versus 51.7% (355) in women with a mean age of 68 (SD 18.64). A phlebitis rate of 11.93% was detected, with catheter caliber and insertion site factors being directly related to the presence of phlebitis.</div></div><div><h3>Conclusions</h3><div>The presence of phlebitis is marked by both modifiable factors, being recommended the use of small caliber devices and the forearm area the indicated ones to decrease the rate of phlebitis.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 4","pages":"Article 502298"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saloa Unanue-Arza , Orlaith Hernon , Selene Lurueña-Rodríguez , Caitriona Duggan , Victoria Armenteros-Yeguas , Peter J. Carr
{"title":"Quality of life instruments for patients with peripherally inserted vascular access devices: A scoping review","authors":"Saloa Unanue-Arza , Orlaith Hernon , Selene Lurueña-Rodríguez , Caitriona Duggan , Victoria Armenteros-Yeguas , Peter J. Carr","doi":"10.1016/j.enfcle.2025.102145","DOIUrl":"10.1016/j.enfcle.2025.102145","url":null,"abstract":"<div><h3>Objective</h3><div>To identify studies that assess the quality of life of people with a peripheral intravenous catheter (PIVC), a midline catheter (MC) and a peripheral insertion central catheter (PICC).</div></div><div><h3>Method</h3><div>Using a scoping review design we included studies that reported the quality of life of adult patients with the aforementioned vascular access devices. With a specific keyword search strategy performed in December 2023 we searched, CINAHL, Embase, Cochrane, Scopus and ProQuest databases. There were no restrictions on the date of publication and studies in English, Spanish or Portuguese were included. Following our inclusion an exclusion criteria, extracted findings reported with the patterns, advances, gaps, evidence for practice and research framework.</div></div><div><h3>Results</h3><div>Of 6317 sources we included 151 papers for full text screening and included 21 studies for data extraction and interpretation. PICCs were the primary catheter reported in seven studies. All remaining studies included more than one device. The most frequently used questionnaire was European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (eight studies) followed by the Short Form Health Survey, the Karnofsky scale, Functional Living Index-Cancer questionnaire, Palliative Care Outcome Scale FACT-B questionnaire. In eight studies a researcher developed without validated questions were used alone or combined with other validated instruments.</div></div><div><h3>Conclusion</h3><div>There are no validated questionnaires measuring patient quality of life with specifically for three of the most commonly inserted vascular access devices used in healthcare to date. Opportunities exist to develop and validate a patient related and catheter device specific quality of life instrument.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 4","pages":"Article 102145"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical trial: Comparison of pressurized infusion saline systems with and without heparin for the maintenance of vascular access in critically ill patients","authors":"Mònica Maqueda-Palau , Jaime González-Sánchez","doi":"10.1016/j.enfcle.2025.502187","DOIUrl":"10.1016/j.enfcle.2025.502187","url":null,"abstract":"<div><h3>Aim</h3><div>To evaluate the efficacy of 0.9% saline solution versus heparinized solution for maintaining the patency of intravascular catheters.</div></div><div><h3>Method</h3><div>Single-center, randomized, controlled, single-blind clinical trial. Population: patients with intravascular arterial and/or central venous catheters. Variables: age, sex, admission diagnosis, catheter type and location, duration of catheter placement, catheter functionality, reason for removal, antiplatelet treatment, Activated Partial Thromboplastin Time (APTT), and International Normalized Ratio (INR) values. Data collection was carried out using an ad hoc questionnaire. SPSS v.26 software was used for statistical analysis, including descriptive analysis (median and IQR), Mann-Whitney U test, variable association (chi-square test), and logistic regression. A p-value < 0.05 was considered the indicator of a significant difference.</div></div><div><h3>Results</h3><div>Data were collected from 373 patients, of whom 68,4% were male. Heparin was administered to 202 patients (54,2%) and 0.9% saline to 171 patients (45,8%). A total of 595 catheters were analyzed: 221 (37,1%) arterial catheters, 229 (38,5%) centrally inserted central venous catheters, and 145 (24,4%) peripherally inserted central venous catheters. A total of 51 complications (8,6%) were detected, with a higher incidence in the heparin group (10,4% versus 6,3%). Among all complications, significant differences were observed by catheter type, with an incidence of 11,8% in arterial catheters, compared to 7,4% in centrally inserted central venous catheters and 5,5% in peripherally inserted central venous catheters.</div></div><div><h3>Conclusions</h3><div>No significant differences were observed in maintaining catheter patency between systems using heparinized pressurization and those using 0.9% saline solution.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 4","pages":"Article 502187"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enrique Castro-Sánchez , Ismael Fernández-Fernández , Ian Blanco-Mavillard
{"title":"Implementation sciences: Transformative potential for the advancement of nurses in vascular access care","authors":"Enrique Castro-Sánchez , Ismael Fernández-Fernández , Ian Blanco-Mavillard","doi":"10.1016/j.enfcle.2025.502306","DOIUrl":"10.1016/j.enfcle.2025.502306","url":null,"abstract":"<div><div>This special article addresses the complexity of vascular access care and explores how implementation science can act as a catalyst to optimize vascular nursing practice. Although vascular access care is crucial, its quality is often unsatisfactory due to the diversity of procedures, technologies, and the need to adapt to each patient. Despite numerous improvement interventions, high complication rates and suboptimal use of these vascular devices persist.</div><div>Implementation science can be a crucial strategy to overcome these identified challenges, recognizing the behaviors of healthcare professionals, especially nurses, and their relevance to ensure quality care within the local and organizational context. In this sense, it is challenging to integrate implementation science into the nursing practice of vascular care, such as resistance to change and resource constraints, but it also offers opportunities for innovation and interdisciplinary collaboration. We suggest reevaluating specialized nursing roles to focus on implementation of interventions and optimizing care decisions related to vascular access. This integration requires the development of new competencies and an understanding of the organizational context, key elements to ensure the sustainability and effectiveness of interventions.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 4","pages":"Article 502306"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144669032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel Alves, Ana Paula Moreira, Teresa Sousa, Paulo Teles, Filipe Goncalves, Bruno Miguel Magalhães, Carla Sílvia Fernandes
{"title":"Exergames rehabilitation program for postoperative cancer patients undergoing abdominal surgery: A quasi-experimental study.","authors":"Isabel Alves, Ana Paula Moreira, Teresa Sousa, Paulo Teles, Filipe Goncalves, Bruno Miguel Magalhães, Carla Sílvia Fernandes","doi":"10.1016/j.enfcle.2025.502212","DOIUrl":"https://doi.org/10.1016/j.enfcle.2025.502212","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to describe and test a program implemented by a nurse for cancer patients in the postoperative period of abdominal surgery using Wii Fit games. It explored the relationship between the type of game, its duration, and the score obtained with variables such as quality of life, fatigue, balance, anxiety, and depression.</p><p><strong>Methods: </strong>A quasi-experimental project was conducted using a one-group pretest-posttest design to assess the effects of a rehabilitation program utilizing Nintendo Wii Fit. The games included were Wii Fit Aerobics - Basic Step, Wii Fit - Balance Games Penguin Slide, Wii Fit Training Plus - Birds Eye Bulls Eye, and Wii Fit - Hula Hoop. Data were collected 48h post-surgery and on the 7th day post-surgery.</p><p><strong>Results: </strong>Thirty-five patients participated in the study. The evaluation revealed that the scores and durations of the games had significantly related to the outcomes on the scales, with the \"Wii Fit Aerobics - Basic Step\" and \"Wii Fit - Hula Hoop\" games having the most significant impact across multiple aspects.</p><p><strong>Conclusions: </strong>The study demonstrated that the rehabilitation program had a positive effect on the study population, administered by a rehabilitation nurse. The use of exergames may offer a viable solution to the challenges of traditional rehabilitation methods, particularly for cancer patients in the postoperative period.</p>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":" ","pages":"502212"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship between the care need levels of patients hospitalized in the pediatric surgery service and the caregiving burden of their parents: A cross-sectional study.","authors":"Duygu Karaarslan, Nazan Kavak Çelik, Dilek Ergin","doi":"10.1016/j.enfcle.2025.502210","DOIUrl":"10.1016/j.enfcle.2025.502210","url":null,"abstract":"<p><strong>Objectives: </strong>The study was conducted to determine the relationship between the level of care needs of pediatric patients hospitalized in the pediatric surgery service and the caregiving burden of their parents.</p><p><strong>Methods: </strong>A cross-sectional observational study was conducted on an estimated non-probabilistic sample of 126 children and their parents, who were hospitalized in the pediatric surgery service between May and December 2022. For the children, the inclusion criteria were to be between 0 and 18 years of age, to be hospitalized in the pediatric surgery service of a university hospital and not to present communication difficulties. In order to include parents, they had to meet the criteria of remaining in the hospital after surgery. Descriptive and inferential analyses were performed using non-parametric tests with SPSS software. The study was approved by the research ethics committee.</p><p><strong>Results: </strong>The children participating in the study 72.2% (n = 91) were boys. Of the children, 89.7% (n = 113) were hospitalized for 1-10 days, 53.9% (n = 68) were hospitalized due to outpatient surgery and 79.4% (n = 100) were hospitalized for postoperative reasons. The total mean score obtained from the overall Pediatric Surgery Service Patient Classification Scale by children hospitalized in the pediatric surgery service was 28.95 ± 6.25 (level III), and the mean score obtained from the overall Zarit Caregiver Burden Scale by the mothers was 34.04 ± 10.78 (moderate level). There was a significant and positive relationship between the caregiving burden of the mothers and the level of care needs of the children (r = 0.550, P < .001).</p><p><strong>Conclusion: </strong>The mean scores obtained from the overall pediatric surgery service were at a moderate level. There was a significant, positive relationship between these 2 scales.</p>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":" ","pages":"502210"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorgina Serra-López, Antonia Miranda, Ana Soria, Nuria López, Eduardo Castañón, Margarita Majem
{"title":"Clinical practice guide for nurses that optimizes nurse's comprehensive care of patients undergoing immunotherapy.","authors":"Jorgina Serra-López, Antonia Miranda, Ana Soria, Nuria López, Eduardo Castañón, Margarita Majem","doi":"10.1016/j.enfcle.2025.502193","DOIUrl":"https://doi.org/10.1016/j.enfcle.2025.502193","url":null,"abstract":"<p><strong>Introduction: </strong>Immunotherapy is revolutionizing oncological treatment, but its unique toxicity profile emphasizes the need for multidisciplinary teams involving nurses. In the absence of guidelines tailored for nurses, a comprehensive guide focusing on patient history and care is presented.</p><p><strong>Objective: </strong>To outline the methodology for creating a practical guide for nurses, aimed at improving care for patients undergoing oncologic immunotherapy by focusing on comprehensive support and complementing pharmacological treatment.</p><p><strong>Method: </strong>A guide was developed following Evidence-Based Nursing principles, with the involvement of experts from Spanish oncology scientific societies. Through evidence searches, external review, and editing, robust and applicable recommendations were ensured.</p><p><strong>Results: </strong>The guide focuses on toxicity management, incorporating an algorithm for its handling, along with detailed descriptions and recommendations for early symptom identification from the nursing perspective.</p><p><strong>Conclusion: </strong>The guide emphasizes the essential role of oncology nurses in immunotherapy, highlighting their contribution from advanced roles. Endorsed by scientific societies, it serves as an evidence-based resource.</p>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":" ","pages":"502193"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality of life and emotional state of patients who are candidates for CAR-T therapy: Role of the advanced practice nurse","authors":"Mercedes Montoro-Lorite , Gloria García , Cristina Moreno-García , Ariadna Domènech , Pilar Ayora , Carla Ramos","doi":"10.1016/j.enfcle.2025.502188","DOIUrl":"10.1016/j.enfcle.2025.502188","url":null,"abstract":"<div><h3>Introduction</h3><div>CAR-T therapy is indicated in patients with refractory disease who usually present comorbidities, toxicities associated with previous treatments, and disease instability. Additionally, they must travel close to the infusion center, incurring financial and psychosocial costs. Our study aims to describe the quality of life and psycho-emotional state of candidates for CAR-T therapy.</div></div><div><h3>Methods</h3><div>An observational study was conducted from January to December 2022. The inclusion criteria were being 18 years or older, eligible for CAR-T therapy, and able to understand Spanish. Sociodemographic, clinical variables and Hospital Anxiety and Depression and quality of life scales were collected.</div></div><div><h3>Results</h3><div>One hundred and four participants were recruited, among them, seventy percent did not live in their usual residence. Seventy-five percent of the participants had depression, 76% anxiety, and 78% emotional function impairment. No statistically significant differences between the presence of anxiety/depression associated with not residing in their usual address (p 0.056) or receiving psychological care in their center of origin (p 0.583) were found. However, a correlation between the presence of anxiety/depression among participants referred to the psychology service by the Advanced Practice Nurse (APN) (p < 0.001) was found.</div></div><div><h3>Conclusions</h3><div>In conclusion, assessing the quality of life and psycho-emotional state of candidates for CAR-T therapy with validated scales allows us to identify candidates presenting anxiety and depression with the goal of improving the management of their emotional health. The APN's role is crucial in detecting complications and facilitating early referral to the psychology team.</div></div>","PeriodicalId":72917,"journal":{"name":"Enfermeria clinica (English Edition)","volume":"35 3","pages":"Article 502188"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}