Emerging trends in drugs, addictions, and health最新文献

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LSTM and CNN hybrid model for enhanced fingerprint recognition LSTM与CNN混合模型增强指纹识别
Emerging trends in drugs, addictions, and health Pub Date : 2025-04-11 DOI: 10.1016/j.etdah.2025.100174
Nahla Abdulnabee Sameer , Bashar M. Nema
{"title":"LSTM and CNN hybrid model for enhanced fingerprint recognition","authors":"Nahla Abdulnabee Sameer ,&nbsp;Bashar M. Nema","doi":"10.1016/j.etdah.2025.100174","DOIUrl":"10.1016/j.etdah.2025.100174","url":null,"abstract":"<div><div>The paper introduces an advanced hybrid model combining Convolutional Neural Networks (CNN) and Long Short-Term Memory (LSTM) networks to enhance fingerprint detection and matching within large datasets. The CNN component is employed for feature extraction and learning from image data, while the LSTM component is utilized for sequence prediction in temporal series, yielding optimal results compared to existing methods based on specific criteria. This hybrid approach achieves a fingerprint recognition accuracy of 99.85 %. The proposed method effectively reduces errors in recognition and false rejection rates in fingerprint recognition systems, thereby improving overall usability and security. The integration of CNN and LSTM in fingerprint recognition signifies a substantial advancement in biometric authentication technology, with potential applications in law enforcement, border security, and access control systems.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100174"},"PeriodicalIF":0.0,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steroid and illicit drug abuse in the health and fitness community: A systematic review of evidence 健康和健身社区的类固醇和非法药物滥用:证据的系统回顾
Emerging trends in drugs, addictions, and health Pub Date : 2025-04-01 DOI: 10.1016/j.etdah.2025.100172
Abdullah Al Hamid, Latifah Alomani, Alhanoof Aljuresan, Wasan Alahmad, Zainab Alluwaim
{"title":"Steroid and illicit drug abuse in the health and fitness community: A systematic review of evidence","authors":"Abdullah Al Hamid,&nbsp;Latifah Alomani,&nbsp;Alhanoof Aljuresan,&nbsp;Wasan Alahmad,&nbsp;Zainab Alluwaim","doi":"10.1016/j.etdah.2025.100172","DOIUrl":"10.1016/j.etdah.2025.100172","url":null,"abstract":"<div><h3>Background and aims</h3><div>Anabolic androgenic steroids (AAS) have become a significant concern within the health and fitness community, particularly among athletes seeking enhanced performance. This systematic review investigates the prevalence, motivation, physiological and psychological effects, and risks of AAS use while identifying gaps in knowledge surrounding these substances.</div></div><div><h3>Methods</h3><div>A systematic search of PubMed, Google Scholar, Scopus, and Web of Science was conducted for studies published between 2014 and 2024. Inclusion criteria focused on research exploring athletes’ experiences with AAS, specifically side effects and usage patterns. Data extraction followed a standardized template, and study quality was assessed using the Joanna Briggs Institute (JBI) and Critical Appraisal Skills Programme (CASP) tools.</div></div><div><h3>Findings</h3><div>From 13,387 identified records, 56 studies met the inclusion criteria. AAS use was prevalent across various regions and demographics, with rates ranging from 6.4 % to 29.3 % globally among gym participants, depending on the population and setting. In Saudi Arabia, the prevalence was notably high at 29.3 %, reflecting unique regional factors. Motivations for AAS use consistently included enhancing physical performance, improving body image, and achieving a competitive edge. Awareness of AAS-related risks was alarmingly low across all regions, with only 38.1 % of users recognizing health concerns such as hypertension and hair loss. Misuse was universally associated with severe physical and physiological complications, including cardiovascular issues, and psychological disorders like depression and aggression.</div></div><div><h3>Conclusions</h3><div>AAS misuse is a complex issue driven by performance goals and societal pressures. Targeted educational interventions are urgently needed to enhance awareness of the associated risks and legal implications. Future research should prioritize strategies to mitigate misuse and foster healthier practices within fitness communities.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100172"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of substance use on oral health: Analyzing the DMFT index among addiction treatment patients in Bojnurd City 物质使用对口腔健康的影响:博伊诺德市成瘾治疗患者DMFT指数分析
Emerging trends in drugs, addictions, and health Pub Date : 2025-03-29 DOI: 10.1016/j.etdah.2025.100173
Fatemeh Farazi , Faezeh Kaviyani , Hassan Saadati , Ruhollah Shakeri , Hamid Tavakoli Ghouchani
{"title":"The impact of substance use on oral health: Analyzing the DMFT index among addiction treatment patients in Bojnurd City","authors":"Fatemeh Farazi ,&nbsp;Faezeh Kaviyani ,&nbsp;Hassan Saadati ,&nbsp;Ruhollah Shakeri ,&nbsp;Hamid Tavakoli Ghouchani","doi":"10.1016/j.etdah.2025.100173","DOIUrl":"10.1016/j.etdah.2025.100173","url":null,"abstract":"<div><h3>Background</h3><div>Substance use presents significant health challenges for users, including oral and dental disorders. This study aimed to investigate the Decayed, Missing, and Filled Teeth (DMFT) index and its associated factors in individuals affected by substance use.</div></div><div><h3>Methods</h3><div>This cross-sectional study included 223 voluntary participants who attended addiction treatment clinics in Bojnurd City. Following completion of the demographic questionnaire, the participants underwent oral examinations under adequate illumination on a standard chair, and their DMFT index was recorded.</div></div><div><h3>Results</h3><div>The mean age of the study participants was 50.21 years. A statistically significant positive correlation was observed between age and the DMFT index (<em>P</em> &lt; 0.001). Place of residence had a notable association with DMFT, with urban residents exhibiting lower DMFT scores than others (<em>P</em> &lt; 0.001). Employed participants had lower DMFT scores than homemakers and unemployed participants (<em>P</em> &lt; 0.001). Participants with lower educational levels had higher DMFT index scores (<em>P</em> = 0.001). The type of substance used showed a significant relationship with DMFT (<em>P</em> &lt; 0.001), and the duration of substance use demonstrated a direct and significant correlation with DMFT (<em>P</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The results of this study indicate a high DMFT index among individuals who used substances, with missing teeth comprising the majority of the DMFT index.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100173"},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143806937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning in oncology: Transforming cancer diagnosis, prognosis, and treatment 肿瘤学中的深度学习:改变癌症的诊断、预后和治疗
Emerging trends in drugs, addictions, and health Pub Date : 2025-02-14 DOI: 10.1016/j.etdah.2025.100171
Tiago Cunha Reis
{"title":"Deep learning in oncology: Transforming cancer diagnosis, prognosis, and treatment","authors":"Tiago Cunha Reis","doi":"10.1016/j.etdah.2025.100171","DOIUrl":"10.1016/j.etdah.2025.100171","url":null,"abstract":"<div><div>Deep learning (DL) has emerged as a transformative force in oncology, offering unprecedented capabilities in cancer diagnosis, treatment planning, and prognosis. The integration of DL models with vast and complex datasets, including genomic, transcriptomic, and imaging data, has paved the way for more precise and personalized cancer care. In particular, DL's application in drug efficacy and toxicity prediction is gaining traction, addressing the critical challenge of high drug failure rates in clinical development. By leveraging large datasets and sophisticated algorithms, DL models can predict drug responses and optimize treatment strategies, ultimately improving patient outcomes. Additionally, DL-driven automation in medical imaging processing and report generation is revolutionizing radiology, enhancing diagnostic accuracy and consistency. This review explores the current advancements in DL applications across various aspects of oncology, emphasizing the potential of AI-driven tools to enhance the accuracy, efficiency, and personalization of cancer care. Despite the significant progress, challenges such as model validation, ethical considerations, and the need for transparent AI systems remain. Addressing these challenges will be crucial in realizing the full potential of DL in transforming oncology practices.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100171"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introducing CounseLLMe: A dataset of simulated mental health dialogues for comparing LLMs like Haiku, LLaMAntino and ChatGPT against humans 介绍CounseLLMe:一个模拟心理健康对话的数据集,用于将俳句、LLaMAntino和ChatGPT等法学硕士与人类进行比较
Emerging trends in drugs, addictions, and health Pub Date : 2025-01-31 DOI: 10.1016/j.etdah.2025.100170
Edoardo Sebastiano De Duro, Riccardo Improta, Massimo Stella
{"title":"Introducing CounseLLMe: A dataset of simulated mental health dialogues for comparing LLMs like Haiku, LLaMAntino and ChatGPT against humans","authors":"Edoardo Sebastiano De Duro,&nbsp;Riccardo Improta,&nbsp;Massimo Stella","doi":"10.1016/j.etdah.2025.100170","DOIUrl":"10.1016/j.etdah.2025.100170","url":null,"abstract":"<div><div>We introduce CounseLLMe as a multilingual, multi-model dataset of 400 simulated mental health counselling dialogues between two state-of-the-art Large Language Models (LLMs). These conversations - of 20 quips each - were generated either in English (using OpenAI’s GPT 3.5 and Claude-3’s Haiku) or Italian (with Claude-3’s Haiku and LLaMAntino) and with prompts tuned with the help of a professional in psychotherapy. We investigate the resulting conversations through comparison against human mental health conversations on the same topic of depression. To compare linguistic features, knowledge structure and emotional content between LLMs and humans, we employed textual forma mentis networks, i.e. cognitive networks where nodes represent concepts and links indicate syntactic or semantic relationships between concepts in the dialogues’ quips. We find that the emotional structure of LLM-LLM English conversations matches the one of humans in terms of patient-therapist trust exchanges, i.e. 1 in 5 LLM-LLM quips contain trust along 10 conversational turns versus the <span><math><mrow><mn>24</mn><mo>%</mo></mrow></math></span> rate found in humans. ChatGPT and Haiku’s simulated English patients can also reproduce human feelings of conflict and pessimism. However, human patients display non-negligible levels of anger/frustration that is missing in LLMs. Italian LLMs’ conversations are worse in reproducing human patterns. All LLM-LLM conversations reproduced human syntactic patterns of increased absolutist pronoun usage in patients and second-person, trust-inducing, pronoun usage in therapists. Our results indicate that LLMs can realistically reproduce several aspects of human patient-therapist conversations and we thusly release CounseLLMe as a public dataset for novel data-informed opportunities in mental health and machine psychology.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100170"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A systematic review on the effectiveness of anti-doping education for university students 大学生反兴奋剂教育效果的系统评价
Emerging trends in drugs, addictions, and health Pub Date : 2025-01-14 DOI: 10.1016/j.etdah.2024.100168
Adam R. Nicholls , Lambros Lazuras , Michael Petrou , Ornella Corazza , Carlos Santos , António Júlio Nunes , Michał Rynkowski , João F. Martins , Thomas Zandonai , Uta Kühn , Łukasz Tota
{"title":"A systematic review on the effectiveness of anti-doping education for university students","authors":"Adam R. Nicholls ,&nbsp;Lambros Lazuras ,&nbsp;Michael Petrou ,&nbsp;Ornella Corazza ,&nbsp;Carlos Santos ,&nbsp;António Júlio Nunes ,&nbsp;Michał Rynkowski ,&nbsp;João F. Martins ,&nbsp;Thomas Zandonai ,&nbsp;Uta Kühn ,&nbsp;Łukasz Tota","doi":"10.1016/j.etdah.2024.100168","DOIUrl":"10.1016/j.etdah.2024.100168","url":null,"abstract":"<div><h3>Background</h3><div>Doping poses a threat to the integrity of sport and the health of athletes who dope, including university students. In this systematic review, we identified the content of anti-doping education that universities provide, the disciplines mainly targeted by such education (e.g., sports science, medicine, physiotherapy, etc.), and the effectiveness of anti-doping education on university students’ anti-doping knowledge, attitudes, and other related constructs.</div></div><div><h3>Method</h3><div>We systematically searched the literature using nine different search engines, manually searched relevant journals, and used pearl growing.</div></div><div><h3>Results</h3><div>This review included four studies comprising 1,410 university students. The content of the education programmes varied, although information about prohibited substances and rules was included in all interventions. Two studies targeted a specific cohort of students (e.g., medical and sports science students), whereas the other two recruited university students without specifying the subject discipline. All intervention programmes had a positive impact on doping knowledge, two studies had a positive effect on anti-doping attitudes, and one study impacted morality.</div></div><div><h3>Conclusions</h3><div>These four studies are essential, but methodological limitations mean that better-designed education interventions for university students are required. Researchers could assess the effectiveness of education interventions on anti-doping knowledge and key psycho-social variables among this population.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opioid use and opioid overdose in the Netherlands – a 10 years retrospective study of naloxone administration in Dutch emergency departments 荷兰阿片类药物使用和阿片类药物过量——荷兰急诊科纳洛酮用药10年回顾性研究
Emerging trends in drugs, addictions, and health Pub Date : 2025-01-03 DOI: 10.1016/j.etdah.2024.100164
Bram Kok , Joris Holkenborg , Alba van der Have , Brigitte van de Kerkhof – van Bon , Joris Datema , Pieter Veenstra , Djoke Douma-den Hamer , Cornelis Kramers
{"title":"Opioid use and opioid overdose in the Netherlands – a 10 years retrospective study of naloxone administration in Dutch emergency departments","authors":"Bram Kok ,&nbsp;Joris Holkenborg ,&nbsp;Alba van der Have ,&nbsp;Brigitte van de Kerkhof – van Bon ,&nbsp;Joris Datema ,&nbsp;Pieter Veenstra ,&nbsp;Djoke Douma-den Hamer ,&nbsp;Cornelis Kramers","doi":"10.1016/j.etdah.2024.100164","DOIUrl":"10.1016/j.etdah.2024.100164","url":null,"abstract":"<div><h3>Background</h3><div>The number of opioid users in the Netherlands has doubled in the last two decades. To assess if the rise in use also means a rise in severe opioid intoxications, we studied the number of opioid intoxications necessitating naloxone administration in Dutch emergency departments during the last 10 years.</div></div><div><h3>Methods</h3><div>a multi-center retrospective cohort study that uses information of Dutch emergency department visits between 2011 and 2020 was conducted. Information on type of opioid, reason for use, and duration of use was collected. A severe opioid intoxication was defined as a patient with an opioid toxidrome in whom a rapid improvement of symptoms occurred after administration of naloxone.</div></div><div><h3>Results</h3><div>Five emergency departments participated in this study. The number of episodes of naloxone administrations was 311 in 292 unique patients. 187 cases were considered a severe opioid intoxication. Mean annual incidence was 19.5 cases with a maximum annual incidence of 28 cases. The opioid mostly involved was oxycodone in 69 cases (37 %); followed by methadone in 41 cases (22 %) and fentanyl in 26 cases (14 %). 127 cases (68 %) were using opioids since &gt;3 months. 176 cases (94 %) were admitted of whom 96 to the intensive care unit. Twenty three cases died within 30 days (12 %).</div></div><div><h3>Conclusion</h3><div>There is no clear increase in naloxone administration in Dutch emergency departments to treat opioid intoxication between 2011 and 2020. The almost twofold increase in prescription opioids in the Netherlands during the study period is not accompanied by an increase in opioid intoxications in the emergency department.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Made in China: The international supply of illicit Semaglutide and weight-loss medicines online 中国制造:非法西马鲁肽和减肥药的国际在线供应
Emerging trends in drugs, addictions, and health Pub Date : 2024-12-26 DOI: 10.1016/j.etdah.2024.100169
Luke A. Turnock , Evelyn Hearne , Lambros Lazuras
{"title":"Made in China: The international supply of illicit Semaglutide and weight-loss medicines online","authors":"Luke A. Turnock ,&nbsp;Evelyn Hearne ,&nbsp;Lambros Lazuras","doi":"10.1016/j.etdah.2024.100169","DOIUrl":"10.1016/j.etdah.2024.100169","url":null,"abstract":"<div><h3>Background</h3><div>The use of GLP-1 medicines for weight-loss purposes is increasingly widespread. While these drugs are available as prescription medicines in the UK, there is an expansive illicit market for their supply operating online. This study investigates the scope and impact of illicit weight-loss medicines supplied online through a scoping review of an e-commerce platform – Made-in-China.com – where a large number of Chinese-based sellers are advertising GLP-1 medicines and related weight-loss drugs to European consumers.</div></div><div><h3>Methods</h3><div>The researchers undertook a preliminary examination of available product and supplier pages on Made-in-China.com through a search of 10 key terms relating to weight-loss medicines, and qualitative analysis of product and seller pages for the first 30 results returned for each term. Data from these pages was analysed thematically. All searches were conducted in a single month in 2024.</div></div><div><h3>Findings</h3><div>document how the platform operates, including ease of access, the extent of weight-loss medicine listings offered, and how product is promoted by sellers, including warnings of product being ‘for research use’, as well as physique-related promotional imagery. We explore the potential harms of counterfeit semaglutide being sold in branded packaging that suggests it may be ‘legitimate’, as well as how sellers advertise their ‘legitimacy’ to potential buyers through details of shipping practices, images of lab equipment, and claims of lab tests to verify product quality.</div></div><div><h3>Discussion</h3><div>We consider how public health policy should address the potential harms arising from this website, with particular focus on the easy access to counterfeit prescription-only medicines provided by platforms such as made-in-china.com, which are likely to be substandard and pose a potential risk to users. We also consider the difficulties of regulating international drug supply in the context of differing legal jurisdictions, and the need to educate the public on the risks of illicit market GLP-1 medicines.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100169"},"PeriodicalIF":0.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “A meta-analysis on the relationship between the use of electronic media and psychological well-being” [Emerging Trends in Drugs, Addictions, and Health, 4 (2024) Article 100162] “关于使用电子媒体与心理健康之间关系的荟萃分析”的勘误表[毒品、成瘾和健康的新趋势,4(2024)第100162条]
Emerging trends in drugs, addictions, and health Pub Date : 2024-12-26 DOI: 10.1016/j.etdah.2024.100167
Dong Liu , Roy F. Baumeister , Chia-chen Yang
{"title":"Corrigendum to “A meta-analysis on the relationship between the use of electronic media and psychological well-being” [Emerging Trends in Drugs, Addictions, and Health, 4 (2024) Article 100162]","authors":"Dong Liu ,&nbsp;Roy F. Baumeister ,&nbsp;Chia-chen Yang","doi":"10.1016/j.etdah.2024.100167","DOIUrl":"10.1016/j.etdah.2024.100167","url":null,"abstract":"","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100167"},"PeriodicalIF":0.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use patterns of classic, novel, and herbal opioids 使用经典、新型和草药类阿片的模式
Emerging trends in drugs, addictions, and health Pub Date : 2024-12-14 DOI: 10.1016/j.etdah.2024.100166
Elisabeth Prevete , Natasha L. Mason , Kim P. C. Kuypers , Eef L. Theunissen , Pablo Mallaroni , Massimo Pasquini , Johannes G. Ramaekers
{"title":"Use patterns of classic, novel, and herbal opioids","authors":"Elisabeth Prevete ,&nbsp;Natasha L. Mason ,&nbsp;Kim P. C. Kuypers ,&nbsp;Eef L. Theunissen ,&nbsp;Pablo Mallaroni ,&nbsp;Massimo Pasquini ,&nbsp;Johannes G. Ramaekers","doi":"10.1016/j.etdah.2024.100166","DOIUrl":"10.1016/j.etdah.2024.100166","url":null,"abstract":"<div><h3>Background</h3><div>Data on use patterns and psychological and physical effects of novel synthetic opioids (NSOs) and herbal opioids like kratom <em>(Mitragyna speciosa)</em> lags behind that of classic opioids.</div></div><div><h3>Aims</h3><div>This study aimed to describe use patterns, adverse events, subjective experience and motivation of use with classic, novel and herbal opioids.</div></div><div><h3>Methods</h3><div>A two-part survey was used. The first part examined the prevalence, use patterns (dosage, administration route, duration of effects), and associated adverse events of classic, novel and herbal opioids. The second part delved into detailed retrospective experiences of survey responders with an opioid of preferred choice, mostly kratom.</div></div><div><h3>Results</h3><div>Between May 2020 and February 2023, 467 respondents started the survey, of which 310 met the inclusion criteria. Of these, 52 % (<em>N</em> = 161) completed the first part, 65.6 % (<em>N</em> = 105) started the second part of which 72 completed. Most respondents were male, highly educated, based in North America or Europe, often using multiple opioids. A total of twenty-seven different compounds were reported, of which hydrocodone/dihydrocodeine, kratom, acetylfentanyl, and U-47700 were used the most. A wide range of doses was reported for each compound. Median effect durations ranged between 3 and 4 h for most of the compounds. Administration routes varied, with oral intake being most prevalent. Fentanyl analogues were often administered intravenously. Physical/psychological adverse events were frequently reported by users of oxycodone, kratom, acetylfentanyl, and U-47700. User reports revealed that both kratom and classic opioids were used for recreational and medical purposes, including ameliorating pain, addiction/withdrawal, anxiety, and mood enhancement.</div></div><div><h3>Conclusion</h3><div>Psychological and physical adverse events were widely present among classic, novel and herbal opioids suggesting a need for risk monitoring worldwide. Similarities between classic opioids and kratom include medical utility as well as addictive potential.</div></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"5 ","pages":"Article 100166"},"PeriodicalIF":0.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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