ECS sensors plusPub Date : 2022-03-15DOI: 10.1149/2754-2726/ac5ddd
Raluca-Ioana Ștefan-van Staden
{"title":"Perspective—Challenges in Biomedical Analysis: From Classical Sensors to Stochastic Sensors","authors":"Raluca-Ioana Ștefan-van Staden","doi":"10.1149/2754-2726/ac5ddd","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5ddd","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42853764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-11DOI: 10.1149/2754-2726/ac5cdf
Fernanda Da Silva Santos, Leandro Vitor Silva, Paulo Victor Soares Campos, Carolina Medeiros Strunkis, Camilla Machado Gentil Ribeiro, M. O. Salles
{"title":"Review—Recent Advances of Electrochemical Techniques in Food, Energy, Environment, and Forensic Applications","authors":"Fernanda Da Silva Santos, Leandro Vitor Silva, Paulo Victor Soares Campos, Carolina Medeiros Strunkis, Camilla Machado Gentil Ribeiro, M. O. Salles","doi":"10.1149/2754-2726/ac5cdf","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5cdf","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47170699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-10DOI: 10.1149/2754-2726/ac5c7a
Dalton L. Glasco, A. Sheelam, Nguyen H. B. Ho, Art Matthew Mamaril, Melissa King, J. G. Bell
{"title":"Editors’ Choice—Review—3D Printing: An Innovative Trend in Analytical Sensing","authors":"Dalton L. Glasco, A. Sheelam, Nguyen H. B. Ho, Art Matthew Mamaril, Melissa King, J. G. Bell","doi":"10.1149/2754-2726/ac5c7a","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5c7a","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44778567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-08DOI: 10.1149/2754-2726/ac5b9f
T. Hyodo, Wataru Sakata, T. Ueda, Y. Shimizu
{"title":"Effects of Surface Modification of Platinum Electrodes with Gold on Hydrogen-Sensing Properties of Diode-Type Sensors","authors":"T. Hyodo, Wataru Sakata, T. Ueda, Y. Shimizu","doi":"10.1149/2754-2726/ac5b9f","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5b9f","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43121688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-04DOI: 10.1149/2754-2726/ac5ac6
Vishal Chaudhary, A. Kaushik, H. Furukawa, A. Khosla
{"title":"Review—Towards 5th Generation AI and IoT Driven Sustainable Intelligent Sensors Based on 2D MXenes and Borophene","authors":"Vishal Chaudhary, A. Kaushik, H. Furukawa, A. Khosla","doi":"10.1149/2754-2726/ac5ac6","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5ac6","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46545416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-01DOI: 10.1149/2754-2726/ac60b2
Julia Chung, Lior Sepunaru, Kevin W Plaxco
{"title":"On the Disinfection of Electrochemical Aptamer-Based Sensors.","authors":"Julia Chung, Lior Sepunaru, Kevin W Plaxco","doi":"10.1149/2754-2726/ac60b2","DOIUrl":"https://doi.org/10.1149/2754-2726/ac60b2","url":null,"abstract":"<p><p>Electrochemical aptamer-based (EAB) sensors encompass the only biosensor approach yet reported that is simultaneously: (1) independent of the chemical or enzymatic reactivity of its target, rendering it general; (2) continuous and real-time; and (3) selective enough to deploy <i>in situ</i> in the living body. Consistent with this, <i>in vivo</i> EAB sensors supporting the seconds-resolved, real-time measurement of multiple drugs and metabolites have been reported, suggesting the approach may prove of value in biomedical research and the diagnosis, treatment, and monitoring of disease. However, to apply these devices in long-duration animal models, much less in human patients, requires that they be free of any significant pathogen load. Thus motivated, here we have characterized the compatibility of EAB sensors with standard sterilization and high-level disinfection techniques. Doing so, we find that, while many lead to significant sensor degradation, treatment with CIDEX OPA (0.55% <i>ortho-</i>phthalaldehyde) leads to effective disinfection without causing any detectable loss in sensor performance.</p>","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703871/pdf/nihms-1798110.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9667587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-01DOI: 10.1149/2754-2726/ac5fb3
Alexander Scott, R. Pandey, Survanshu Saxena, Enas A. Osman, Yingfu Li, L. Soleymani
{"title":"A Smartphone Operated Electrochemical Reader and Actuator that Streamlines the Operation of Electrochemical Biosensors","authors":"Alexander Scott, R. Pandey, Survanshu Saxena, Enas A. Osman, Yingfu Li, L. Soleymani","doi":"10.1149/2754-2726/ac5fb3","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5fb3","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48807273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-03-01Epub Date: 2022-04-07DOI: 10.1149/2754-2726/ac5b2e
Ruolan Fan, Yanfeng Li, Kwang-Won Park, Jiale Du, Lin Hui Chang, Eric R Strieter, Trisha L Andrew
{"title":"A Strategy for Accessing Nanobody-Based Electrochemical Sensors for Analyte Detection in Complex Media.","authors":"Ruolan Fan, Yanfeng Li, Kwang-Won Park, Jiale Du, Lin Hui Chang, Eric R Strieter, Trisha L Andrew","doi":"10.1149/2754-2726/ac5b2e","DOIUrl":"10.1149/2754-2726/ac5b2e","url":null,"abstract":"<p><p>Nanobodies are single variable domain antibodies isolated from camelids and are rapidly distinguishing themselves as ideal recognition elements in biosensors due to their comparative stability, ease of production and isolation, and high binding affinities. However, transducing analyte binding by nanobodies in real time is challenging, as most nanobodies do not directly produce an optical or electrical signal upon target recognition. Here, we report a general strategy to fabricate sensitive and selective electrochemical sensors incorporating nanobodies for detecting target analytes in heterogeneous media, such as cell lysate. Graphite felt can be covalently functionalized with recombinant HaloTag-modified nanobodies. Subsequent encapsulation with a thin layer of a hydrogel using a vapor deposition process affords encapsulated electrodes that directly display a decrease in current upon antigen binding, without added redox mediators. Differential pulse voltammetry affords clear and consistent decreases in electrode current across multiple electrode samples for specific antigen concentrations. The change in observed current vs increasing antigen concentration follows Langmuir binding characteristics, as expected. Importantly, selective and repeatable target binding in unpurified cell lysate is only demonstrated by the encapsulated electrode, with an antigen detection limit of ca. 30 pmol, whereas bare electrodes lacking encapsulation produce numerous false positive signals in control experiments.</p>","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40683836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ECS sensors plusPub Date : 2022-02-15DOI: 10.1149/2754-2726/ac5523
A. Turner
{"title":"Perspective—An Age of Sensors","authors":"A. Turner","doi":"10.1149/2754-2726/ac5523","DOIUrl":"https://doi.org/10.1149/2754-2726/ac5523","url":null,"abstract":"","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64430059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}