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Exosomes, the Key Players in Cell-To-Cell Communication as the Universal Nano-Sized Disease Sensors of the Future 外泌体是细胞间通信的关键参与者,是未来的通用纳米级疾病传感器
ECS sensors plus Pub Date : 2023-07-21 DOI: 10.1149/2754-2726/ace981
K. Mohammadi, S. Badilescu, Anirban Ghosh, M. Packirisamy
{"title":"Exosomes, the Key Players in Cell-To-Cell Communication as the Universal Nano-Sized Disease Sensors of the Future","authors":"K. Mohammadi, S. Badilescu, Anirban Ghosh, M. Packirisamy","doi":"10.1149/2754-2726/ace981","DOIUrl":"https://doi.org/10.1149/2754-2726/ace981","url":null,"abstract":"Exosomes are nanovesicles shed by cells into the extracellular space. From an engineering point of view, exosomes can be assimilated to a complex system, that is, an arrangement of parts that together exhibit a behavior that the individual constituents do not. The authors argue that the unique composition of exosomes as well as their involvement in cell-to-cell communication and monitoring a multitude of diseases, justify entirely looking at exosomes, in the future, as universal sensors of diseases. In this paper, after the short background information on exosomes, the authors show how they are involved in the progress of different diseases.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46894623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engineering Biosensors and Biomedical Detection Devices from 3D-Printed Technology 来自3d打印技术的工程生物传感器和生物医学检测设备
ECS sensors plus Pub Date : 2023-07-10 DOI: 10.1149/2754-2726/ace5bd
Minghui Liang, Xiang Liu, Yuying Chong, Ziyun Ye, Lei Zhao, Qiang Yu, Kai Tang, Anqi Geng, Bo Hu, Guanqun Ge, Shifang Yuan
{"title":"Engineering Biosensors and Biomedical Detection Devices from 3D-Printed Technology","authors":"Minghui Liang, Xiang Liu, Yuying Chong, Ziyun Ye, Lei Zhao, Qiang Yu, Kai Tang, Anqi Geng, Bo Hu, Guanqun Ge, Shifang Yuan","doi":"10.1149/2754-2726/ace5bd","DOIUrl":"https://doi.org/10.1149/2754-2726/ace5bd","url":null,"abstract":"Limitation of 3D construction ability, complex preparation processes and developing customer demands have promoted people to find low-cost, rapid prototyping, and simple operation methods to produce novel functional devices in the near future. Among various techniques, 3D-printed technology is a promising candidate for the fabrication of biosensors and biomedical detection devices with a wide variety of potential applications. This review offers four important 3D printing techniques for biosensors and biomedical detection devices and their applications. The principle and printing process of 3D-printed technologies will be generalized, and the printing performance of many 3D printers will be compared. Despite the resolution restrictions of 3D-printed, these technologies have already shown promising applications in many biosensors and biomedical detection devices, such as 3D-printed microfluidic devices, 3D-printed optical devices, 3D-printed electrochemical devices, and 3D-printed integrated devices. Some of the most representative examples will also be discussed here, demonstrating that 3D-printed technology can rationally design biosensors and biomedical detection devices and achieve important applications in microfluidic, optical, electrochemical, and integrated devices.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41987633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editors’ Choice—Luminescent Oxygen Sensors: Valuable Tools for Spatiotemporal Exploration of Metabolism in In Vitro Systems 编辑的选择-发光氧传感器:在体外系统代谢的时空探索有价值的工具
ECS sensors plus Pub Date : 2023-07-05 DOI: 10.1149/2754-2726/ace202
Tyler Z Sodia, K. Cash
{"title":"Editors’ Choice—Luminescent Oxygen Sensors: Valuable Tools for Spatiotemporal Exploration of Metabolism in In Vitro Systems","authors":"Tyler Z Sodia, K. Cash","doi":"10.1149/2754-2726/ace202","DOIUrl":"https://doi.org/10.1149/2754-2726/ace202","url":null,"abstract":"A common biological theme on Earth is the importance of oxygen, regardless of an organism’s metabolic capabilities. This commonality makes the quantification of O2 essential in understanding life as we know it. There are many sensing methods that enable researchers to measure this important analyte, but not all sensors are compatible with every system. This perspective highlights common O2 sensing formats (and recent innovations) with the goal of guiding the reader towards a sensor choice for their desired application. We emphasize the importance of exploring unfamiliar metabolic processes, commercializing new sensors, and establishing collaborations for maximizing innovation and accelerating discovery.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47175372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cephalopods as a Natural Sensor-Display Feedback System Inspiring Adaptive Technologies 头足类作为一种自然传感器显示反馈系统的自适应技术
ECS sensors plus Pub Date : 2023-06-01 DOI: 10.1149/2754-2726/acdbdc
Lasanthi Sumathirathne, Taehwan Kim, Duncan Q. Bower, L. Deravi
{"title":"Cephalopods as a Natural Sensor-Display Feedback System Inspiring Adaptive Technologies","authors":"Lasanthi Sumathirathne, Taehwan Kim, Duncan Q. Bower, L. Deravi","doi":"10.1149/2754-2726/acdbdc","DOIUrl":"https://doi.org/10.1149/2754-2726/acdbdc","url":null,"abstract":"Nature is full of exemplary species that have evolved personalized sensors and actuating systems that interface with and adapt to the world around them. Among them, cephalopods are unique. They employ fast-sensing systems that trigger structural changes to impart color changes through biochemical and optoelectronic controls. These changes occur using specialized optical organs that receive and respond to signals (light, temperature, fragrances, sound, and textures) in their environments. We describe features that enable these functions, highlight engineered systems that mimic them, and discuss strategies to consider for future cephalopod-inspired sensor technologies.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48833747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review—Environmental Biosensors for Agro-Safety Based on Electrochemical Sensing Mechanism with an Emphasis on Pesticide Screening 综述——以农药筛选为重点的基于电化学传感机制的农业安全环境生物传感器
ECS sensors plus Pub Date : 2023-06-01 DOI: 10.1149/2754-2726/acde5d
V. N. Dhamu, Durgasha C. Poudyal, Manish Samson, A. Paul, S. Muthukumar, Shalini Prasad
{"title":"Review—Environmental Biosensors for Agro-Safety Based on Electrochemical Sensing Mechanism with an Emphasis on Pesticide Screening","authors":"V. N. Dhamu, Durgasha C. Poudyal, Manish Samson, A. Paul, S. Muthukumar, Shalini Prasad","doi":"10.1149/2754-2726/acde5d","DOIUrl":"https://doi.org/10.1149/2754-2726/acde5d","url":null,"abstract":"Climate change directly affects all aspects of the environment and accounts for changes in our surroundings seen or unseen. With the growing need for accountability in the agricultural commercial and regulatory spheres, there is a widely accepted consensus that there needs to be quantitative information on the different environmental entities to understand and solve challenges posed towards food production and agricultural activities. The main purpose of the creation of this article is to propagate an era of quantitative metrics to better assess environmental health which can adversely impact human health. This review assesses 3 different environmental vectors prone to pollution and in high contact with human entities. This review also discusses different electrochemical sensing platforms used as biosensors for the detection of a wide myriad of pollutants with an adverse effect on human health. Furthermore, the breakdown of each section includes a survey of the evolution and design of various sensor platforms that are aimed towards a comprehensive monitoring platform for pollutant screening with an emphasis on agro-safety and environmental health. Detailed pesticide screening case-studies are also explored for a better understanding of the current electrochemical biosensors that exist for the sole purpose of environmental monitoring.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44684875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Perspective-The Feasibility of Continuous Protein Monitoring in Interstitial Fluid. 透视间质液中蛋白质连续监测的可行性。
ECS sensors plus Pub Date : 2023-06-01 Epub Date: 2023-04-28 DOI: 10.1149/2754-2726/accd7e
Thomas Young, Vincent Clark, Netzahualcóyotl Arroyo-Currás, Jason Heikenfeld
{"title":"Perspective-The Feasibility of Continuous Protein Monitoring in Interstitial Fluid.","authors":"Thomas Young,&nbsp;Vincent Clark,&nbsp;Netzahualcóyotl Arroyo-Currás,&nbsp;Jason Heikenfeld","doi":"10.1149/2754-2726/accd7e","DOIUrl":"10.1149/2754-2726/accd7e","url":null,"abstract":"<p><p>Real-time continuous monitoring of proteins in-vivo holds great potential for personalized medical applications. Unfortunately, a prominent knowledge gap exists in the fundamental biology regarding protein transfer and correlation between interstitial fluid and blood. Additionally, technological sensing will require affinity-based platforms that cannot be robustly protected in-vivo and will therefore be challenged in sensitivity, longevity, and fouling over multi-day to week timelines. Here we use electrochemical aptamer sensors as a model system to discuss further research necessary to achieve continuous protein sensing.</p>","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":"2 2","pages":"027001"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9456291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Review—Basic and Advanced Inertial Navigation Fluid-Based Technology 综述-基于流体的基本和先进惯性导航技术
ECS sensors plus Pub Date : 2023-04-27 DOI: 10.1149/2754-2726/acd0c0
R. Elaswad, N. El-Sheimy, A. A. Mohamad
{"title":"Review—Basic and Advanced Inertial Navigation Fluid-Based Technology","authors":"R. Elaswad, N. El-Sheimy, A. A. Mohamad","doi":"10.1149/2754-2726/acd0c0","DOIUrl":"https://doi.org/10.1149/2754-2726/acd0c0","url":null,"abstract":"The article reviews most published inertial sensor technologies, including dynamically tuned, optical, MEMS vibratory, mechanical, solid-state, and fluid-based. The working principles of the technologies are elaborated. Also, the advantages and disadvantages of those sensors are laid out. Owing to its excellent overall performance, such as its simple structure, low cost, large measurement range, etc, the current review focuses on the state-of-the-art of fluid-based technology of accelerometers and gyroscopes. The sensing elements of the fluid-based technology that are used in the accelerometer and gyroscope are explained. Moreover, a comparison and analysis of those sensing elements are presented. The comparison shows that the thermal resistor has five orders of magnitude which is the highest dynamic range. However, the porous transducer is higher in bandwidth which is almost 120 Hz. Furthermore, the particle imaging velocimetry gyroscope (PIVG) is reviewed. The PIVG is an innovative technology that is used to measure the angular rate where fluid is used as proof of mass. The review shows that the PIVG is low-cost and almost drift-free. Additionally, compared to commercially available gyroscopes, PIVG provides a superior signal-to-noise ratio (SNR).","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44581462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Watch-Type Dual-Mode Wearable Health Device 手表型双模可穿戴健康设备
ECS sensors plus Pub Date : 2023-03-24 DOI: 10.1149/2754-2726/acc74d
Hyusim Park, Liem H. T. Nguyen, Shanthala Lakshminarayana, Yuze Sun, Sungyong Jung
{"title":"Watch-Type Dual-Mode Wearable Health Device","authors":"Hyusim Park, Liem H. T. Nguyen, Shanthala Lakshminarayana, Yuze Sun, Sungyong Jung","doi":"10.1149/2754-2726/acc74d","DOIUrl":"https://doi.org/10.1149/2754-2726/acc74d","url":null,"abstract":"Wearable devices can be found as numerous types of health devices ranging from monitoring hazardous environments to detecting physiological signals. Its utilities have also shown encouraging improvements toward personalized healthcare. Thus, many kinds of wearable health devices (WHD) have been reported and developed. Those reports highlight their efficiency in monitoring harmful environmental factors and various diseases for diagnostic and treatment purposes. This paper proposes a watch-type of dual-mode WHD that can perform gaseous phase detection to monitor dangerous environmental situations such as bad air quality and aqueous phase detection to measure physiological signals from human sweat or blood. The proposed system was fabricated on a printed circuit board and its size is 3 cm × 3 cm which is suitable as a wearable device. It also consumes very low power and has capabilities of wired/wireless charging and wired/wireless communication. Furthermore, customized windows and Android applications have been developed to visualize obtained data in a user’s computer or smartphone. The system was tested both electrically and chemically and showed promising results as the WHD.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46879189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Modified Fe3O4 Magnetite Core@Shell Type Nanomaterials for Highly-Responsive LPG Sensing: A Comparative Analysis 用于高响应LPG传感的改性Fe3O4磁铁矿Core@Shell型纳米材料的比较分析
ECS sensors plus Pub Date : 2023-03-13 DOI: 10.1149/2754-2726/acc3ab
Shakti Singh, A. Dzeranov, L. Bondarenko, K. Kydralieva, G. Dzhardimalieva, A. Babaytsev, G. Kugabaeva, N. Golubeva, B. Yadav
{"title":"Modified Fe3O4 Magnetite Core@Shell Type Nanomaterials for Highly-Responsive LPG Sensing: A Comparative Analysis","authors":"Shakti Singh, A. Dzeranov, L. Bondarenko, K. Kydralieva, G. Dzhardimalieva, A. Babaytsev, G. Kugabaeva, N. Golubeva, B. Yadav","doi":"10.1149/2754-2726/acc3ab","DOIUrl":"https://doi.org/10.1149/2754-2726/acc3ab","url":null,"abstract":"The present work focuses on the synthesis of Fe3O4 magnetite core@shell type nanoparticles modified with three types of ligands: Magnetite with activated carbon (MAC), Magnetite with silica (tetraethoxysilane, TEOS, and 3-aminopropyltriethoxysilane, APTES) (MTA) and Magnetite with silica, APTES and humic acids (MTAH). The MTAH sample shows greater porosity in comparison to MTA, and MAC samples. The band gap of MTAH is 4.08 eV, which is higher than MTA (2.92 eV), and MAC (2.80 eV). Rietveld quantitative phase analysis of all derivatives was performed and compared with all three samples. The LPG sensing at room temperature shows the highest sensor response of 9.42, in comparison to 3.87 sensor response for MAC, and 4.60 for MTA. This approximately double sensor response increment is justified with the help of band gap, porosity, and size of all 3 the samples. The MTAH sample shows the lowest response-recovery time of 9.33 and 10.78 s respectively in comparison to MAC and MTA samples. In conclusion, this manuscript describes the synthesis procedure of different derivatives of Fe3O4 core@shell materials along with the relation of LPG sensing with different parameters of the materials.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49090336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Progression in Quantum Sensing/Bio-Sensing Technologies for Healthcare 用于医疗保健的量子传感/生物传感技术进展
ECS sensors plus Pub Date : 2023-03-06 DOI: 10.1149/2754-2726/acc190
Vibhas Chugh, Adreeja Basu, A. Kaushik, A. Basu
{"title":"Progression in Quantum Sensing/Bio-Sensing Technologies for Healthcare","authors":"Vibhas Chugh, Adreeja Basu, A. Kaushik, A. Basu","doi":"10.1149/2754-2726/acc190","DOIUrl":"https://doi.org/10.1149/2754-2726/acc190","url":null,"abstract":"The 5th/6th generation bio-sensing technology is an emerging field which connects smart technologies like Artificial Intelligence, Internet of Things and Machine Learning with efficient micro/nano-enabled sensing platform for making point-of-care (POC) devices to investigate health management strategies. Recently, the integration and interfacing between quantum measurement, signaling, and optimized bio-actives has led to investigate the minute biological events with anomalous sensitivity. Such technologies are expected to provide the possibility to measure and record changes at quantum scales with varying pressure, temperature, and electromagnetic fields. Considering current scenarios, this perspective critically highlights state-of-art quantum sensing technology along with their challenges and prospects.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42817259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
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