Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society最新文献

Role of 3D imaging and tissue-clearing method in gastrointestinal neoplasms: Will it offer a glimpse into the future of endoscopic diagnostics? 三维成像和组织清除法在胃肠道肿瘤中的作用：它能让人看到内窥镜诊断的未来吗？

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-04-08 DOI: 10.1111/den.15033

Kazunori Takada

引用次数: 0

Ergonomic endoscopy: Path to your sustainable endoscopy practice.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-04-07 DOI: 10.1111/den.15032

Takahiro Utsumi, Yasushi Sano, Hiroshi Seno

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Efficacy and safety of remimazolam for sedation during endoscopic procedures in Japanese: A prospective phase III clinical trial.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-04-03 DOI: 10.1111/den.15030

Hisatomo Ikehara, Ryoji Ichijima, Yoji Takeuchi, Jun Kanazawa, Takuya Wada, Kosuke Okuwaki, Tomoya Ueda, Hirofumi Kogure, Chika Kusano, Hiroyuki Ono

{"title":"Efficacy and safety of remimazolam for sedation during endoscopic procedures in Japanese: A prospective phase III clinical trial.","authors":"Hisatomo Ikehara, Ryoji Ichijima, Yoji Takeuchi, Jun Kanazawa, Takuya Wada, Kosuke Okuwaki, Tomoya Ueda, Hirofumi Kogure, Chika Kusano, Hiroyuki Ono","doi":"10.1111/den.15030","DOIUrl":"https://doi.org/10.1111/den.15030","url":null,"abstract":"Objectives: Remimazolam is a general anesthetic with a short elimination half-life and its pharmacokinetics are less affected by liver and kidney function. It may be useful for sedation during endoscopic procedures in patients. This single-arm clinical trial aimed to evaluate the efficacy and safety of remimazolam for sedation in patients undergoing endoscopic procedures.Methods: Patients undergoing endoscopic procedures were included in this study. Remimazolam was administered intravenously with opioid analgesics, and the endoscopic procedure was started after an efficient level of sedation (Modified Observer's Assessment of Alertness/Sedation score ≤3) was achieved. The primary end-point for efficacy was the sedation success rate during the endoscopic procedures. Data on adverse events were collected for safety evaluation.Results: Sixty-two patients were included in the analysis. The sedation success rate of 93.5% (84.3-98.2%) exceeded the threshold success rate of 80% (P = 0.004). In all, 98.4% of patients were appropriately sedated before endoscope insertion. The median time from the first dose of remimazolam to achieving sedation was 4.0 min, while the median time from the end of the endoscopic procedure to being deemed ready to leave the room was 2.0 min. Adverse events were observed in 22 cases (35.5%). The severity of adverse events was moderate in five cases (8.1%), mild in 17 cases (27.4%), and there was no severe case.Conclusion: Sedation with remimazolam plus opioid analgesics was effective and well tolerated, regardless of endoscopic procedure site. These findings suggest that remimazolam is a useful sedative during endoscopic procedures.","PeriodicalId":72813,"journal":{"name":"Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gel-immersion-assisted endoscopic injection sclerotherapy under observation with Texture and Color enhancement imaging for esophageal varices. 食管静脉曲张的凝胶浸泡辅助内窥镜注射硬化剂疗法与纹理和色彩增强成像观察。

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-04-03 DOI: 10.1111/den.15029

Tsunetaka Kato, Takuto Hikichi, Takumi Yanagita

引用次数: 0

Dual thin grasping forceps-assisted over-the-scope clip closure for delayed perforation in the remnant stomach after endoscopic submucosal dissection.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-04-03 DOI: 10.1111/den.15022

Minami Hashimoto, Takuto Hikichi, Takumi Yanagita

引用次数: 0

Type 2 and type 3 gastric neuroendocrine tumors have high risk of lymph node metastasis: Systematic review and meta-analysis.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-04-01 DOI: 10.1111/den.15026

Yohei Ogata, Waku Hatta, Takeshi Kanno, Masahiro Saito, Xiaoyi Jin, Naoki Asano, Tomoyuki Koike, Akira Imatani, Yuhong Yuan, Atsushi Masamune

{"title":"Type 2 and type 3 gastric neuroendocrine tumors have high risk of lymph node metastasis: Systematic review and meta-analysis.","authors":"Yohei Ogata, Waku Hatta, Takeshi Kanno, Masahiro Saito, Xiaoyi Jin, Naoki Asano, Tomoyuki Koike, Akira Imatani, Yuhong Yuan, Atsushi Masamune","doi":"10.1111/den.15026","DOIUrl":"https://doi.org/10.1111/den.15026","url":null,"abstract":"Objectives: Lymph node metastasis (LNM) is crucial in determining treatment strategies for gastric neuroendocrine tumors (gNETs). While type 3 is considered more aggressive than types 1 and 2 within the clinical subtype of gNETs, the supporting data were insufficient, due to their rarity. We aimed to study the prevalence and risk factors associated with LNM in gNETs.Methods: We searched electronic databases from 1990 to 2023 to identify case-control and cohort studies regarding gNETs resected either endoscopically or surgically. The primary outcome measured was the pooled prevalence of LNM in gNETs. Secondary outcomes included categorizing the prevalence of LNM by clinical subtypes and identifying pathological risk factors associated with LNM in gNETs.Results: We included 28 studies, involving 1742 patients, among whom 240 had LNM (pooled prevalence rate, 11.8%; 95% confidence interval 7.6-17.9%). The pooled prevalence rates of LNM for type 1, type 2, and type 3 gNETs were 6.0%, 38.5%, and 23.2%, respectively. Type 2 (odds ratio [95% confidence interval] 11.53 [3.46-38.49]) and type 3 (6.88 [3.79-12.49]) gNETs exhibited a higher risk for LNM compared to type 1. Pathological risk factors for LNM included tumor size >10 mm (4.18 [1.91-9.17]), tumor invasion into the muscularis propria or deeper (11.21 [3.50-35.92]), grade 2/grade 3 (5.96 [2.65-13.40]), and lymphovascular invasion (34.50 [6.70-177.51]).Conclusion: We demonstrated that type 2 gNETs, as well as type 3, had a high risk of LNM. Additionally, four pathological risk factors associated with LNM were identified.","PeriodicalId":72813,"journal":{"name":"Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic removal of migrated gastric band ring after Fobi pouch gastric bypass.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-03-26 DOI: 10.1111/den.15017

Povilas Kavaliauskas, Aurelijus Grigaliunas, Gintautas Brimas

引用次数: 0

Revolutionizing gastroesophageal reflux disease diagnosis and treatment: Promise of EPSIS and EARTh.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-03-26 DOI: 10.1111/den.15027

Hironari Shiwaku

引用次数: 0

Clinical Practice Guidelines for post-ERCP pancreatitis 2023.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-03-25 DOI: 10.1111/den.15004

Shuntaro Mukai, Yoshifumi Takeyama, Takao Itoi, Tsukasa Ikeura, Atsushi Irisawa, Eisuke Iwasaki, Akio Katanuma, Katsuya Kitamura, Mamoru Takenaka, Morihisa Hirota, Toshihiko Mayumi, Toshio Morizane, Ichiro Yasuda, Shomei Ryozawa, Atsushi Masamune

{"title":"Clinical Practice Guidelines for post-ERCP pancreatitis 2023.","authors":"Shuntaro Mukai, Yoshifumi Takeyama, Takao Itoi, Tsukasa Ikeura, Atsushi Irisawa, Eisuke Iwasaki, Akio Katanuma, Katsuya Kitamura, Mamoru Takenaka, Morihisa Hirota, Toshihiko Mayumi, Toshio Morizane, Ichiro Yasuda, Shomei Ryozawa, Atsushi Masamune","doi":"10.1111/den.15004","DOIUrl":"https://doi.org/10.1111/den.15004","url":null,"abstract":"The Clinical Practice Guidelines for post-ERCP pancreatitis (PEP) 2023 provide updated recommendations for the prevention, diagnosis, and management of PEP. Endoscopic retrograde cholangiopancreatography (ERCP), a valuable procedure for diagnosing and treating pancreatobiliary diseases, can result in PEP as the most common adverse event. Since the first guidelines were published in 2015, advances in techniques and new research findings have necessitated this revision. The guidelines developed using the GRADE methodology target adult patients undergoing ERCP. They offer a comprehensive framework for clinicians to minimize the risk of PEP. For high-risk patients, endoscopic ultrasound before ERCP is recommended to avoid unnecessary procedures. The guidelines also discuss procedural and patient-related risk factors for PEP, highlighting that operator experience does not significantly affect PEP rates if performed under the supervision of skilled endoscopists. The diagnostic criteria include monitoring serum pancreatic enzyme levels postprocedure, and early computed tomography is advised in suspected cases. For treatment, the guidelines recommend following acute pancreatitis protocols. Key preventive measures include the use of temporary pancreatic duct stents and rectal nonsteroidal anti-inflammatory drugs, both of which are supported by strong evidence for reducing the incidence of PEP. Overall, these guidelines aim to enhance clinical outcomes by reducing PEP incidence and improving its management through evidence-based practices.","PeriodicalId":72813,"journal":{"name":"Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guidelines for endoscopic management of nonvariceal upper gastrointestinal bleeding (second edition).

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Pub Date : 2025-03-21 DOI: 10.1111/den.15019

Mitsuhiro Fujishiro, Mikitaka Iguchi, Satoshi Ono, Kohei Funasaka, Yasuhisa Sakata, Tatsuya Mikami, Mikinori Kataoka, Shunji Shimaoka, Tomoki Michida, Yoshinori Igarashi, Shinji Tanaka

{"title":"Guidelines for endoscopic management of nonvariceal upper gastrointestinal bleeding (second edition).","authors":"Mitsuhiro Fujishiro, Mikitaka Iguchi, Satoshi Ono, Kohei Funasaka, Yasuhisa Sakata, Tatsuya Mikami, Mikinori Kataoka, Shunji Shimaoka, Tomoki Michida, Yoshinori Igarashi, Shinji Tanaka","doi":"10.1111/den.15019","DOIUrl":"https://doi.org/10.1111/den.15019","url":null,"abstract":"The Japan Gastroenterological Endoscopy Society has prepared Guidelines for Endoscopic Practice in Nonvariceal Upper Gastrointestinal Bleeding as part of the initiative to develop evidence-based endoscopic practice guidelines. Hemorrhagic gastroduodenal (peptic) ulcers are the primary cause of nonvariceal upper gastrointestinal bleeding. With the advent of a super-aged society, the cases caused by Helicobacter pylori are on the decline, whereas those caused by drugs (e.g. aspirin) have been increasing. Endoscopic hemostasis is currently the first-line treatment for nonvariceal upper gastrointestinal bleeding, and various methods have been devised for this purpose. It is recommended to stabilize the vital signs of the patient before and after endoscopic hemostasis with appropriate management based on an assessment of the severity of illness, in addition to the administration of acid secretion inhibitors. These guidelines describe the evaluation and initial treatment of nonvariceal upper gastrointestinal bleeding, as well as the selection of endoscopic hemostasis for nonvariceal upper gastrointestinal bleeding and its management after endoscopic hemostasis. This is achieved by classifying nonvariceal upper gastrointestinal bleeding into two main categories, namely, peptic ulcer and other types of gastrointestinal bleeding. We prepared statements for any available literature with supporting evidence, including the levels of evidence and recommendations. New evidence has been pooled since the publication of the first edition in this area; however, the levels of evidence and recommendations mostly remain low.","PeriodicalId":72813,"journal":{"name":"Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0