Current research in medical sciences最新文献

{"title":"Effect of the Combination of Native Herb with Motherwort on Anti-Inflammatory, Anti-Fatigue, and Hypertensive Hypoxia Tolerance","authors":"Han‐jun Ma, Shibo Zhao, Yuxin Wei, Zong-Qing He, Q. Wei, Xue‐Yi Huang, Qi Wei, Liyu Su, Suoyi Huang","doi":"10.56397/crms.2023.06.04","DOIUrl":"https://doi.org/10.56397/crms.2023.06.04","url":null,"abstract":"Objective: To investigate the in vivo anti-inflammatory, anti-fatigue, and hypertensive hypoxia tolerance effects of earth ginseng with motherwort and its combination on mice. Methods: Male mice were divided into 6 groups according to their body weight: blank control group, native ginseng group, motherwort group, and three experimental groups with a 1:1 ratio of native ginseng and motherwort. 1.5, 4.5, and 7.5 g-kg-1 -d-1 were given to the three experimental groups. The blank control group was instilled with saline, and the earth ginseng group and motherwort group were given 1.5 g-kg -d-1-1 of the corresponding extracts. After 21 d of continuous gavage, the ear swelling test by xylene, the weight swimming test, and the high-pressure hypoxia tolerance test were performed. Also, the experimental indexes were measured, the liver weight was weighed, and the liver weight coefficient was calculated. Results: In the anti-inflammatory experiment, there was a significant difference in the swelling inhibition effect between the two single-flavored groups compared with the control group, the low-dose group compared with the two single-flavored groups, and the medium- and high-dose groups compared with the low-dose group (P < 0.05). In the weight swimming experiment and high-pressure hypoxia tolerance experiment, compared with the control group, the mice in the earth ginseng group and the motherwort group showed a significant improvement in weight swimming time and high-pressure hypoxia tolerance time (P＜0.05); compared with the two single herb groups, the mice in the low dose group showed a statistically significant improvement in weight swimming time and high-pressure hypoxia tolerance time (P＜0.05); compared with the low dose group, the mice in the high dose group showed a statistically significant improvement in weight swimming time and high-pressure hypoxia tolerance time (P＜0.05). Compared with the low-dose group, the high-dose group had a statistically significant (P < 0.05) improvement in weight-bearing swimming time and hyperbaric hypoxia tolerance time. Compared with the control group, the liver weight coefficient of the earth ginseng group was statistically significant (P＜0.05); compared with the two single herb groups, the liver weight coefficient of the low-dose group was statistically significant (P＜0.05); compared with the low-dose group, the liver weight coefficient of the middle and high-dose groups were statistically significant (P＜0.05). Conclusion: Native herbal medicine and its combination have significant anti-inflammatory, anti-fatigue, and high-pressure hypoxia tolerance effects, and the anti-inflammatory effect was positively correlated with the increase of the extract concentration; the anti-fatigue and high-pressure hypoxia tolerance effects were the best in the high-dose group.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84876020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress Based on Serious Complication of Stroke in Patients with Chronic Kidney Disease","authors":"Yunchuan Tian, Qingyang Zhu, Yonglian Tang, Rongkun Li, Jiang Xiao","doi":"10.56397/crms.2023.06.07","DOIUrl":"https://doi.org/10.56397/crms.2023.06.07","url":null,"abstract":"Patients with chronic renal insufficiency (CKD) in the uremic stage can suffer various degrees of damage to various organ systems throughout the body, with the nervous system being common and severe. Chronic kidney disease (CKD) complicated with stroke has a high incidence and poor prognosis, which brings a heavy burden to patients and society. Understanding the risk factors of uremic patients complicated with stroke and taking preventive measures as soon as possible is of great significance for controlling the progress of the disease. The risk factors of uremic patients complicated with stroke are complex and diverse. Traditional risk factors include hypertension, diabetes, atrial fibrillation, dyslipidemia, etc. Non traditional risk factors such as genetic susceptibility, uremia, anemia, mineral and bone abnormalities can also promote the occurrence of stroke. In addition, dialysis related risk factors such as insufficient cerebral perfusion, increased arterial stiffness, and increased blood pressure variability can also cause stroke. Therefore, it is important to identify the risk factors of stroke in uremic patients as early as possible and take targeted preventive measures.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87592498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Description and Treatment Progress of Postpartum Body Pain in Chinese Medicine","authors":"Yinhang Fu, Yingchun Tai, Yiyao Yang","doi":"10.56397/crms.2023.06.06","DOIUrl":"https://doi.org/10.56397/crms.2023.06.06","url":null,"abstract":"Postpartum body pain is one of the common postpartum diseases, the damage to the patient’s physical and mental health can not be ignored. The recognition and treatment of postpartum body pain in traditional Chinese medicine mainly take qi and blood, Zang-fu organs and ying wei as the main points of syndrome differentiation. Its main etiology and pathogenesis are postpartum deficiency of qi and blood, wind-cold and dampness evil invading human body, the dysfunction of each viscera and the disharmony of camp and health. According to the cause, the treatment can be summarized as supplementing qi and blood, harmonizing Yingwei, dispelling wind and dispersing cold, activating collages and relieving pain, regulating zang fu organs and so on. TCM treatment focuses on the holistic view, and its systematic treatment through early intervention, multiple means and multiple approaches has the advantages of high safety, significant efficacy and low recurrence rate. Clinical syndrome differentiation is not limited to one of the above types, but this article can provide treatment ideas for this disease.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"150 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76025999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Perception and Feasibility of Community Health Influencers, Promoters and Service (CHIPS) Program Among Community Health Workers in Nkanu West and Awgu Local Government Areas, Enugu State, Nigeria","authors":"N. Ugwunna, K. Enwonwu, C. Ani, B. Anozie, O. Arising, V. Aroh","doi":"10.56397/crms.2023.06.11","DOIUrl":"https://doi.org/10.56397/crms.2023.06.11","url":null,"abstract":"Background: Primary health care (PHC) is the bedrock of our National Health Policy. PHC has two components: Community level and Primary health care facility level. Universal Health Cover cannot be achieved without significant investment in the community level component. Hitherto, the community component of PHC remains a neglected area of PHC program. CHIPS, a community-based programme was designed to allow traditional institution to select individuals who will administer basic medical needs and referring people in their communities to designated medical facilities when necessary. Method: This is a cross-sectional descriptive community-based study that was conducted among community health workers in Nkanu West and Awgu Local Government Areas of Enugu State Nigeria using self-administered questionnaire. Convenience sampling technique was used to select community health workers in the two local government areas. Results: 77.4% of the study population were not aware of the program. 26.9% are of the opinion that the families in the communities will welcome the idea of home visits. 23.3% perceived the implementation process to be slow, there was poor community awareness (22.0%), poor community participation (19.3%) and no community mobilization (19.3%) yet. Conclusion: From our study, the response rate on how best to organize CHIPS and the challenges it may face, is low. The striking thing is that the challenges of the past community health workers are still that of the present. So it is of utmost importance to constructively look at the content of the planning, implementation and its evaluation, and then draw strength from the weaknesses of the already existing community health programs.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74086332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Hypogalactia Modern Treatment of Traditional Chinese Medicine","authors":"Yiyao Yang, Yingchun Tai, Yinhang Fu","doi":"10.56397/crms.2023.06.13","DOIUrl":"https://doi.org/10.56397/crms.2023.06.13","url":null,"abstract":"Postpartum hypogalactia was postpartum clinical common disease, mainly in breastfeeding, maternal milk little, or no milk, enough to feed the baby. Modern medicine thinks, milk secreted by the body’s neural and humoral regulation, hypothalamus and pituitary gland secretion of various hormones. Sucking and emptying of the breast is vital to maintain breast lactation. According to Chinese medicine, breast milk is produced by the body's qi, blood and fluids and depends on the flow of qi, which is the only way to produce enough milk to feed the baby. Maternal nutrition, sleep, mood can affect the normal secretion of milk juice. Breastfeeding is good for maternal and child are, in recent years, more and more get advocate and support. Hypogalactia of modern treatment has added new means and methods, including breast massage, “Three principles”, that is, the earlier they touch, early sucking, opened early milk; Acupuncture and cupping therapy; Psychological nursing intervention; Low frequency pulse for instrument and other advanced equipment. This paper mainly on postpartum hypogalactia heal 1 healing progress were reviewed, in order to provide reference for clinical treatment, better exert advantages of modern treatment of traditional Chinese medicine.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78672660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress in the Research of Reflux Nephropathy","authors":"Yunchuan Tian, Jiang Xiao, Yonglian Tang, Rongkun Li, Qingyang Zhu","doi":"10.56397/crms.2023.06.01","DOIUrl":"https://doi.org/10.56397/crms.2023.06.01","url":null,"abstract":"Reflux nephropathy (RN) is a renal disease caused by Vesicoureteral Reflux (VUR) and Intrarenal Reflux (IRR), resulting in renal cortical scar (localized atrophy) and focal glomerulosclerosis. RN is one of the important causes of end-stage renal diseases (ESRD). The most basic pathological feature of RN is kidney scarring. Common clinical manifestations are persistent or recurrent urinary tract infection, albuminuria, hypertension, nocturia, polyuria, lumbago, urinary calculi, etc. Due to the hidden condition of RN, doctors in various departments, especially in pediatrics, nephrology and urology, must strengthen their understanding and understanding of this disease, so as to facilitate the early detection and diagnosis of this disease. Correct conservative treatment of Western medicine, surgical treatment when necessary, and reasonable integrated treatment of Chinese and Western medicine are of great significance for the prevention and treatment of the progression from RN to ESRD.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75723564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Processes and Hygiene to Protect Against Spread and Mutations of COVID-19","authors":"E. Bryndin, I. Bryndina","doi":"10.56397/crms.2023.06.02","DOIUrl":"https://doi.org/10.56397/crms.2023.06.02","url":null,"abstract":"Our planet is a living being that has its own protective viral mechanism. Viruses are activated when people intervene too zealously in the natural processes on the planet and worsen the environment. With a decrease in the spiritual level of society, deterioration of the environment, climate change, pollution of water and soil and other catastrophic violations of natural processes on the planet, an epidemic and the process of mutation of viruses begins, as a result of which more and more of their species and strains appear. The coronavirus is becoming more and more infectious, more and more often affects the young and, according to some reports, aggravates the course of the disease. COVID-19 acquires variability and increases infectiousness in people with weak immunity. Mutations of COVID-19 and infection will stop if the path of transmission of coronavirus from person to person is interrupted. To do this, you need to observe natural and medical protective measures, acquire appropriate knowledge and skills and have protective equipment available.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75495022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in the Diagnosis and Treatment of Cardiogenic Shock in Chinese Medicine and Research","authors":"Ming-Hao Sun, Yuewei Li, Shibo Zhao, Zhonggang Wu, Xiuling Wei","doi":"10.56397/crms.2023.06.05","DOIUrl":"https://doi.org/10.56397/crms.2023.06.05","url":null,"abstract":"Cardiogenic shock belongs to a group of acute and critical illnesses in cardiovascular medicine with a high mortality rate and poor prognosis. Traditional Chinese medicine, as the crystallization of traditional wisdom of Chinese medicine, has made certain progress in the treatment of cardiogenic shock and in improving the prognosis of such patients. This article reviews the latest research results and related reports on the treatment of cardiogenic shock in Chinese medicine, intending to provide front-line clinical workers with treatment ideas and references.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74108283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Health Literacy (LHL) Facts","authors":"Abdul Kader Mohiuddin","doi":"10.56397/crms.2023.06.03","DOIUrl":"https://doi.org/10.56397/crms.2023.06.03","url":null,"abstract":"In order to access, comprehend, and use information to make decisions about their health, people must possess certain personal traits and social resources, which are referred to as health literacy. It can assist us in maintaining good health, preventing illness, and effectively managing existing illnesses. The degree to which a person can locate, comprehend, and make use of information and services to support health-related decisions and actions for themselves and others is known as personal health literacy. Low health literacy is linked to more hospitalizations, more use of emergency care, less use of preventative services, and a worsened ability to understand labels and health messages, a worsened state of health, higher mortality, and more expensive medical care.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81572556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bibliometric Analysis of Tea and Bone from 1989 to 2023","authors":"Dongping Wan, Rui Tang, Shihang Cao, Qiang Zan","doi":"10.56397/crms.2023.06.14","DOIUrl":"https://doi.org/10.56397/crms.2023.06.14","url":null,"abstract":"Background: An increasing body of research has demonstrated a close association between the timing, type, and quantity of tea consumption and bone metabolism and skeletal health. However, to date, there has been a scarcity of systematic literature reviews and quantitative analyses in this field. This project aims to employ a bibliometric approach to systematically analyze and summarize the research on tea and bone health from 1989 to 2023. By visualizing the research hotspots and trends, we seek to gain a comprehensive understanding of the current status of research in this area. Methods: Relevant research articles were retrieved from the Web of Science Core Collection (WoSCC). The collected articles were then subjected to statistical and visualization analyses using CiteSpace and VOSviewer. Key aspects analyzed included the annual publication output, active countries, prolific institutions, authors, core journals, references, and keywords. Results: In total, 932 articles were selected from the WOSCC database, showing an increasing trend in annual publication output. The highest number of publications originated from China (240 articles, accounting for 25.75%), followed by the USA (196 articles, accounting for 21.03%) and Japan (105 articles, accounting for 11.27%). Among institutions, Texas Tech University emerged as the most prolific in terms of productivity, while author Shen, Chwan-Li contributed the highest number of publications (27 articles). The research hotspots in the field of tea and bone studies were identified as osteogenic differentiation, inflammation, and mesenchymal stem cells. Conclusions: The field of tea and bone research is experiencing a vibrant expansion, with ongoing investigations focusing on the intricate connections between tea and inflammation, as well as the mechanisms underlying tea’s impact on bone cell differentiation. However, further exploration is warranted to elucidate and delve deeper into these mechanisms in order to enhance our comprehension in this area.","PeriodicalId":72751,"journal":{"name":"Current research in medical sciences","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79414002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}