{"title":"A Narrative Synthesis Review of Legislation Banning Gender-Affirming Care.","authors":"Jessie Melina Garcia Gutiérrez, Emerson Dusic, Audren J K Bambilla, Arjee Javellana Restar","doi":"10.1007/s40124-024-00320-y","DOIUrl":"10.1007/s40124-024-00320-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>In recent years, there has been a drastic increase in legislation across US states that aims to ban gender-affirming care (GAC) for transgender and nonbinary (trans) youth. We synthesized the literature on bans on GAC, its impacts on medical and mental health providers, trans communities, particularly trans youth and their caregivers (e.g., parents/families), and provided recommendations for future research and advocacy.</p><p><strong>Recent findings: </strong>We highlight several adverse impacts of legislation banning GAC, including: an increase in professional tensions for medical and mental health providers that work with trans youth and worse mental health outcomes for trans youth and their caregivers due to loss of autonomy in accessing evidence-based GAC.</p><p><strong>Summary: </strong>Bans on GAC undermine evidenced-based practices and are resulting in negative health effects for trans communities and youth. Research evidence highlights the need to examine effects of bans at the intersections of gender identity, socioeconomic status, race, and ethnicity.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"12 3","pages":"44-51"},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11935454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Norovirus on Children and Adolescents: Implications for Ongoing Vaccine Development.","authors":"Ming Tan","doi":"10.1007/s40124-025-00355-9","DOIUrl":"10.1007/s40124-025-00355-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>This article highlights the heightened vulnerability of children and adolescents to norovirus infection and discusses the implications for ongoing vaccine development efforts.</p><p><strong>Recent findings: </strong>Young children remain highly vulnerable to norovirus infections and are at an increased risk of severe disease. However, a recent Phase 2b clinical trial in infants failed to demonstrate meaningful protection or other clinical benefits. Similarly, low protective efficacy was observed in adults in a separate Phase 2b clinical evaluation, raising concerns about the complexity of norovirus vaccine development, particularly for young children.</p><p><strong>Summary: </strong>Norovirus continues to pose a significant global health threat, affecting individuals of all ages and contributing to considerable morbidity, mortality, and socioeconomic burden. Children and adolescents are especially vulnerable, as they often spend time in closed or semi-closed environments such as daycare centers and schools, settings commonly associated with norovirus outbreaks. The lack of an FDA-approved norovirus vaccine underscores the urgent need for effective preventive strategies. Several vaccine candidates, utilizing diverse platforms, have advanced to Phase 2 clinical trials and beyond, targeting various age groups. While some have shown promise in adults, a recent Phase 2b clinical trial of a VLP-based vaccine in infants failed to demonstrate sufficient efficacy, and another Phase 2b study of an adenovirus-vectored vaccine reported low efficacy in adults. These findings suggest that novel approaches and strategies may be required to overcome the current challenges in norovirus vaccine development.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 1","pages":"21"},"PeriodicalIF":2.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Courtney A Smith, Anna Pulminskas, Julia Rogers, Anna Fischer, Chelsea Deitelzweig, Chiagoziem Ohamadike, Leslie Lawley, Howa Yeung
{"title":"Managing common dermatologic needs in transgender and gender-diverse adolescents.","authors":"Courtney A Smith, Anna Pulminskas, Julia Rogers, Anna Fischer, Chelsea Deitelzweig, Chiagoziem Ohamadike, Leslie Lawley, Howa Yeung","doi":"10.1007/s40124-025-00344-y","DOIUrl":"10.1007/s40124-025-00344-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>Transgender and gender-diverse (TGD) adolescents often face dermatologic concerns during gender-affirming care but may face limited access to dermatologists. This review aims to provide practical guidance for pediatricians on managing common dermatologic needs in TGD adolescents, including acne, hair growth promotion or removal, and post-surgical scarring within the context of gender-affirming care.</p><p><strong>Recent findings: </strong>Acne management should consider the impact of testosterone therapy and chest binding, with treatment options including topical retinoids, benzoyl peroxide, oral antibiotics, combined oral contraceptives, and spironolactone. Topical minoxidil may be considered for the promotion of facial, and scalp hair growth. Hair removal methods and complications such as pseudofolliculitis barbae should be discussed with TGD adolescents seeking temporary or permanent hair removal. Hypertrophic scarring and keloids may occur after gender-affirming chest reconstruction, with management involving topical silicone gel and adhesive silicone sheeting.</p><p><strong>Summary: </strong>TGD adolescents may struggle to identify specialists trained in gender-affirming dermatologic care and may delay or avoid care due to past mistreatment in clinical settings. Pediatricians play a key role in managing the dermatologic concerns of TGD adolescents by creating a gender-affirming, safe, and supportive care environment and facilitating early dermatology referrals when appropriate.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason M Nagata, Oliver Huang, Jacqueline O Hur, Elizabeth J Li, Christiane K Helmer, Emily Weinstein, Megan A Moreno
{"title":"Health Benefits of Social Media Use in Adolescents and Young Adults.","authors":"Jason M Nagata, Oliver Huang, Jacqueline O Hur, Elizabeth J Li, Christiane K Helmer, Emily Weinstein, Megan A Moreno","doi":"10.1007/s40124-025-00357-7","DOIUrl":"10.1007/s40124-025-00357-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>Although attention has increased on the negative aspects of social media use in adolescents and young adults, social media can have health benefits. This review explores positive health aspects of social media and delivers guidance to clinicians on how to balance attention to the negatives and positives of social media use.</p><p><strong>Recent findings: </strong>Recent findings show social media can play an important role in social connection and identity development in adolescents and young adults. The platforms are also important for mental health support and accessing health information.</p><p><strong>Summary: </strong>Clinicians should have open-ended conversations with adolescents and young adults to understand their social media use patterns. They can use the American Academy of Pediatrics 5 Cs of media use and the family media plan to guide conversations on social media use.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 1","pages":"22"},"PeriodicalIF":2.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eosinophilic Esophagitis, Then and Now: A Review","authors":"Roopali Mittal","doi":"10.1007/s40124-023-00309-z","DOIUrl":"https://doi.org/10.1007/s40124-023-00309-z","url":null,"abstract":"","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139218136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bracken, Rebecca Lenihan, A. Khanijau, E. Carrol
{"title":"The Aetiology and Global Impact of Paediatric Sepsis","authors":"A. Bracken, Rebecca Lenihan, A. Khanijau, E. Carrol","doi":"10.1007/s40124-023-00305-3","DOIUrl":"https://doi.org/10.1007/s40124-023-00305-3","url":null,"abstract":"","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"39 23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manu R. Varma, Ana L. Vasquez Choy, Rakesh Donthula, Brian Feingold
{"title":"Novel Diagnostics for Pediatric Heart Transplant Rejection","authors":"Manu R. Varma, Ana L. Vasquez Choy, Rakesh Donthula, Brian Feingold","doi":"10.1007/s40124-023-00310-6","DOIUrl":"https://doi.org/10.1007/s40124-023-00310-6","url":null,"abstract":"","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"36 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139240353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}