Laura Stamm, Breanna De Leon, Da'Jon M Stoudemire, Milena E Insalaco, Ahona Shirin, Madalayne Martin-Olenski, Carley Daley, Kristefer Stojanovski
{"title":"The Impact of Politicization on Adolescent Medicine Care: A Rapid Review.","authors":"Laura Stamm, Breanna De Leon, Da'Jon M Stoudemire, Milena E Insalaco, Ahona Shirin, Madalayne Martin-Olenski, Carley Daley, Kristefer Stojanovski","doi":"10.1007/s40124-026-00379-9","DOIUrl":"10.1007/s40124-026-00379-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>Increased politicization of health care, exemplified by bans on gender-affirming and reproductive care, has significantly impacted adolescents' ability to receive safe care. We conducted a rapid review of evidence examining politicized health legislation's impact on adolescents' right to health, focusing on reproductive, gender-affirming, and eating disorder care.</p><p><strong>Recent findings: </strong>Politicization of care has impacted adolescents' right to health by creating financial barriers and changes in geographic access. For example, state legislative ban on abortion and gender-affirming care have created care deserts in which adolescents are forced to travel to receive care. These changes have resulted in delays in care, loss of bodily autonomy, and negative impacts on physical and mental health.</p><p><strong>Summary: </strong>The findings of this rapid review have important implications for adolescent medicine clinical practices. Providers caring for adolescents require institutional support and resources to address increased patient psychosocial concerns and potentially higher patient volume as a result of restrictive legislation. Ultimately, policy advocacy is necessary to change legislation disrupting adolescents' right to health.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s40124-026-00379-9.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"14 1","pages":"7"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13346270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason M Nagata, Sahana Nayak, William Choi, Char Potes, Alexander Heuer, Zain Memon, Jonanne Talebloo, Elizabeth J Li, Kevin Bao, Christiane K Helmer, Megan A Moreno, Jason M Lavender
{"title":"Health Benefits of Video Games in Adolescents and Young Adults.","authors":"Jason M Nagata, Sahana Nayak, William Choi, Char Potes, Alexander Heuer, Zain Memon, Jonanne Talebloo, Elizabeth J Li, Kevin Bao, Christiane K Helmer, Megan A Moreno, Jason M Lavender","doi":"10.1007/s40124-026-00376-y","DOIUrl":"10.1007/s40124-026-00376-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>Although studies of outcomes associated with video gaming in adolescence and young adulthood largely focus on potential harms, video game use may also promote certain health benefits. This review synthesizes the positive health outcomes associated with video gaming, while providing recommendations to clinicians for considering and evaluating both beneficial and adverse effects.</p><p><strong>Recent findings: </strong>Recent evidence suggests that video gaming may strengthen the development of cognitive and executive functioning in adolescents and young adults. Moreover, video game use may also contribute positively to social connection and personal identity formation.</p><p><strong>Summary: </strong>Clinicians should engage in open, nonjudgmental dialogue with youth to better explore the context and patterns of their video gaming. The American Academy of Pediatrics' 5 Cs framework and Family Media Plan offer evidence-based frameworks that can be referenced to facilitate thoughtful discussions about video game use.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"14 1","pages":"2"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12945946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason M Nagata, Jacqueline O Hur, Thang Diep, Hasan Alsamman, Eliot D Lee, Alexander Heuer, Henry Huynh, Sahana Nayak, Ryan McBain, Jonathan Cantor, Jason M Lavender
{"title":"Generative Artificial Intelligence Use and Adolescent Mental Health.","authors":"Jason M Nagata, Jacqueline O Hur, Thang Diep, Hasan Alsamman, Eliot D Lee, Alexander Heuer, Henry Huynh, Sahana Nayak, Ryan McBain, Jonathan Cantor, Jason M Lavender","doi":"10.1007/s40124-026-00388-8","DOIUrl":"10.1007/s40124-026-00388-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>To synthesize recent literature on the relationships between generative artificial intelligence (GenAI) use and adolescents' mental health, with particular attention to problematic use and psychiatric vulnerabilities.</p><p><strong>Recent findings: </strong>Emerging evidence suggests associations between GenAI use and a range of adolescent mental health outcomes, including depression, anxiety, psychosis-related experiences, externalizing behaviors, eating disorder risk, and suicidality. Problematic patterns of use, including dependency and emotional reliance, may be particularly relevant among adolescents with preexisting psychiatric vulnerabilities. Current evidence suggests that these relationships may be bidirectional: psychological distress can motivate GenAI use for companionship, emotional support, or escape, while problematic use may reinforce maladaptive beliefs, displace real-world relationships, and amplify existing vulnerabilities. However, evidence remains predominantly cross-sectional, limiting causal inference.</p><p><strong>Summary: </strong>GenAI may interact with and amplify underlying psychiatric vulnerabilities during adolescence, highlighting the importance of understanding patterns and motivations of use. Pediatricians and other clinicians caring for adolescents could consider not only the frequency of GenAI use but also motivations for use, problematic dependency, and socioemotional reliance. Identifying high-risk usage patterns of GenAI through longitudinal research, particularly among youth with preexisting psychiatric risks, may inform the development of tailored screening, intervention, and prevention strategies.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"14 1","pages":"16"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13612636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Hypertriglyceridemia: Lipoprotein Metabolism, Etiology, and Management.","authors":"Hidenori Moriyama, J Nina Ham","doi":"10.1007/s40124-025-00349-7","DOIUrl":"10.1007/s40124-025-00349-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>Hypertriglyceridemia increases the risk of both atherosclerotic cardiovascular disease and acute pancreatitis. While management of dyslipidemia has long been a focus in the care of adult patients, relatively recent recommendations for universal pediatric lipid screening have facilitated earlier and more widespread diagnoses of dyslipidemia in youth. This review highlights lipoprotein metabolism, etiologic classifications, and management strategies to guide clinicians in identifying and treating hypertriglyceridemia in children and adolescents.</p><p><strong>Recent findings: </strong>Novel therapies targeting lipoprotein pathways, particularly angiopoietin-like 3 and apolipoprotein C-III inhibitors, show promise in reducing triglyceride levels among patients with inherited or treatment-refractory conditions. These agents build upon established options (fibrates, omega-3 fatty acid preparations, and statins) that have been adapted from adult practice for pediatric use.</p><p><strong>Summary: </strong>A comprehensive approach to pediatric hypertriglyceridemia integrates lifestyle interventions with pharmacotherapy for those whose levels remain elevated. Timely identification of underlying etiologies, such as obesity, medication-induced hypertriglyceridemia, and rare genetic mutations, is vital. Intervention for extremely high triglyceride levels can mitigate acute pancreatitis risk, while even modest reductions may improve long-term cardiovascular outcomes. By combining appropriate screening, prompt evaluation, and individualized therapies, clinicians can reduce both immediate and long-term complications, thereby improving overall cardiometabolic health in children and adolescents.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12524095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145310100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate Citron-Zafrin, Rachelle Gandica, Natasha Leibel
{"title":"Latest Updates in Prevention and Screening of Type 1 Diabetes Mellitus.","authors":"Kate Citron-Zafrin, Rachelle Gandica, Natasha Leibel","doi":"10.1007/s40124-025-00351-z","DOIUrl":"10.1007/s40124-025-00351-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>We describe the latest guidelines for classification of stages of type 1 diabetes (T1D) and updates regarding screening and prevention of T1D in the pediatric population.</p><p><strong>Recent findings: </strong>Preclinical diabetes is now staged and there are both completed and ongoing trials that have identified therapeutic targets to potentially delay the onset of clinical T1D and the need for insulin therapy. The approval of teplizumab as the first FDA approved pharmacologic agent to delay progression of T1D, makes screening increasingly important.</p><p><strong>Summary: </strong>Type 1 diabetes (T1D) is a chronic disease caused by autoimmune destruction of pancreatic beta cells, resulting in insulin deficiency. Screening for T1D is offered in clinical trials for high-risk individuals, such as family members of those with T1D. Advantages to screening for T1D include prevention of life-threatening diabetic ketoacidosis (DKA) and reduction in the risk of associated morbidity and mortality. T1D is now classified in stages that are defined by the presence of pancreatic autoantibodies and dysglycemia. Teplizumab is a humanized anti-CD3 monoclonal antibody and is the first pharmacologic agent approved by the US Food and Drug Administration (FDA) to delay progression of T1D. Additionally, there have been many trials aimed at identifying additional therapeutic targets to delay onset of clinical T1D and the need for insulin therapy.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145497212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Body Image, Disordered Eating, and Eating Disorders in Gender Diverse Youth.","authors":"Alexandra Allam, Samuel B Seidman, Blair Uniacke","doi":"10.1007/s40124-025-00341-1","DOIUrl":"10.1007/s40124-025-00341-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>We examine the prevalence of body image disturbance, disordered eating, and eating disorders (EDs) among gender diverse youth, and discuss implications and recommendations for providers encountering these intersecting issues in their practice.</p><p><strong>Recent findings: </strong>Increasing evidence demonstrates that transgender and non-binary youth experience greater rates of body image issues, as well as disordered eating and EDs. Gender dysphoria in combination with these body, shape, weight, and food concerns are associated with elevated rates of other comorbid psychiatric problems, each of which place gender diverse youth at risk for adverse outcomes. Routine assessment of gender dysphoria and EDs is necessary for earlier and therefore more successful interventions. Likewise, targeting symptoms of both gender dysphoria and EDs concurrently is critical for optimal results.</p><p><strong>Summary: </strong>Body dissatisfaction, disordered eating and EDs are often related to and comorbid with gender dysphoria, all of which are prevalent among gender diverse youth. Such symptoms are associated with additional psychiatric issues, including depression, anxiety, and suicidal ideation in this population. For earlier intervention and better outcomes, routine screening in primary care settings is necessary, as are referrals to providers who are equipped to treat both gender- and eating-related problems simultaneously.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jia Tan, Byourak Shabane, Etan Orgel, Steven D Mittelman
{"title":"Metabolic Implications of Childhood Cancer.","authors":"Jia Tan, Byourak Shabane, Etan Orgel, Steven D Mittelman","doi":"10.1007/s40124-025-00348-8","DOIUrl":"10.1007/s40124-025-00348-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>Childhood cancer patients and survivors often suffer from obesity and metabolic syndrome. The purpose of this review is to evaluate the available data on how body composition and metabolism are affected by childhood cancer and its treatment.</p><p><strong>Recent findings: </strong>Though severity varies among cancers and treatments, childhood cancer patients often exhibit acute changes in metabolism and body composition during the induction of therapy. Particularly prevalent is a decrease in lean mass accompanied by excess adiposity, often called sarcopenic obesity. These metabolic burdens can last for decades after therapy and contribute to future morbidity and mortality. A few promising studies show that dietary and physical activity interventions may reduce these outcomes.</p><p><strong>Summary: </strong>Body composition and metabolic effects occur during cancer treatment and can increase the risk of chronic disease in survivors. More studies are needed to best plan monitoring and intervention strategies to prevent metabolic syndrome and its sequelae in childhood cancer survivors. the course of the disease.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Danzo, Yomna Anan, Kacie Kidd, Gina Sequeira, Nicole F Kahn
{"title":"Supporting Adolescents Bereaved by Sibling Suicide: A Review of Needs, Gaps, and Opportunities.","authors":"Sarah Danzo, Yomna Anan, Kacie Kidd, Gina Sequeira, Nicole F Kahn","doi":"10.1007/s40124-025-00363-9","DOIUrl":"10.1007/s40124-025-00363-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>Suicide is a leading cause of death among adolescents. However, while there is a growing focus on suicide prevention efforts, there has been very little research on how to support young people bereaved by suicide, particularly adolescent siblings. Given the impact of suicide on the entire family, as well as the increased risk of mental health problems and suicidal behaviors during adolescence, we sought to review the current literature through a family systems lens to identify what is known, current gaps, and needs for future work to be able to better support adolescents bereaved by sibling suicide.</p><p><strong>Recent findings: </strong>Overall, very few studies have examined the impact of sibling suicide on adolescents, and even fewer examine interventions for adolescents who have lost a sibling to suicide.</p><p><strong>Summary: </strong>Findings highlight a critical need for more work focused on developing and rigorously evaluating interventions for adolescents bereaved by sibling suicide. Additional program development and research in this area is critical to improve long term outcomes for adolescents and their families, and to ultimately reduce suicide risk among surviving adolescent siblings.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 1","pages":"26"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic Implications of PCOS.","authors":"Amna Naveed, Rachana Shah, Angelina Bernier, Valeriia Muradova, Eray Savgan Gurol, Melanie Cree, Rachel Whooten","doi":"10.1007/s40124-025-00364-8","DOIUrl":"10.1007/s40124-025-00364-8","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS) is a common endocrine condition among women, with associated cardiometabolic comorbidities. While there are limitations to both the diagnosis of PCOS and cardiometabolic disease within adolescence, there is evidence that adolescents with PCOS have greater risk for insulin resistance, cardiovascular and adipose tissue dysfunction, and hepatic steatosis. This review aims to explore the risk of metabolic disease in adolescents with PCOS and its association with disease phenotypes, offering insight into the evolution of this metabolic risk into adulthood. These findings reinforce the critical need for timely diagnosis of PCOS, combined with targeted lifestyle interventions, to mitigate cardiometabolic risk and shift the trajectory of long-term health outcomes.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Building Strong Foundations: Bone Health in Pediatric Patients with Diabetes.","authors":"Cara V Tillotson, Melissa D Garganta","doi":"10.1007/s40124-025-00365-7","DOIUrl":"10.1007/s40124-025-00365-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>Skeletal development begins in childhood with all bone accrual complete by early adulthood, making bone health an important topic in pediatric medicine. This is especially true for patients with diabetes as these and other chronic conditions are associated with increased lifelong risk of fracture. The purpose of this review is to give a broad overview of bone health in diabetes including etiology, pathogenesis, and current recommendations for management.</p><p><strong>Recent findings: </strong>Studies continue to demonstrate lifelong increased risk of osteoporotic fractures in patients with diabetes. Like all diabetes complications, tight glycemic control, nutrition, and exercise play crucial roles in the prevention of this diabetes complication. Bisphosphonate therapy for osteoporosis in pediatrics is limited to those with a history of fragility fractures.</p><p><strong>Opinion statement: </strong>Pediatricians should promote lifestyle modifications to optimize bone health for all patients with diabetes, including ensuring adequate nutrition (vitamin D and calcium intake), exercise, and glycemic control. Dual-energy x-ray absorptiometry (DXA) scan should be considered for any patient with diabetes and a history of clinically significant fracture (vertebral fracture, low impact long-bone fracture, or multiple fractures). Referral to an endocrinologist with experience in osteoporosis treatment is appropriate for any patient with diabetes and a history of pathologic fracture.</p>","PeriodicalId":72740,"journal":{"name":"Current pediatrics reports","volume":"13 ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146203985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}