Current drug abuse reviews最新文献_第6页

Crisis intervention related to the use of psychoactive substances in recreational settings--evaluating the Kosmicare Project at Boom Festival. 与娱乐场所使用精神活性物质相关的危机干预——Boom Festival上Kosmicare项目的评估。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473708666150107115515

Maria Carmo Carvalho, Mariana Pinto de Sousa, Paula Frango, Pedro Dias, Joana Carvalho, Marta Rodrigues, Tania Rodrigues

{"title":"Crisis intervention related to the use of psychoactive substances in recreational settings--evaluating the Kosmicare Project at Boom Festival.","authors":"Maria Carmo Carvalho, Mariana Pinto de Sousa, Paula Frango, Pedro Dias, Joana Carvalho, Marta Rodrigues, Tania Rodrigues","doi":"10.2174/1874473708666150107115515","DOIUrl":"https://doi.org/10.2174/1874473708666150107115515","url":null,"abstract":"Kosmicare project implements crisis intervention in situations related to the use of psychoactive substances at Boom Festival (Portugal). We present evaluation research that aims to contribute to the transformation of the project into an evidence-based intervention model. It relies on harm reduction and risk minimization principles, crisis intervention models, and Grof's psychedelic psychotherapy approach for crisis intervention in situations related to unsupervised use of psychedelics. Intervention was expected to produce knowledge about the relation between substance use and mental health impact in reducing potential risk related to the use of psychoactive substances and mental illness, as well as an impact upon target population's views of themselves, their relationship to substance use, and to life events in general. Research includes data on process and outcome indicators through a mixed methods approach, collected next to a sample of n=176 participants. Sample size varied considerably, however, among different research measures. 52% of Kosmicare visitors reported LSD use. Over 40% also presented multiple drug use. Pre-post mental state evaluation showed statistically significant difference (p<.05) confirming crisis resolution. Crisis episodes that presented no resolution were more often related with mental health outburst episodes, with psychoactive substance use or not. Visitors showed high satisfaction with intervention (n=58) and according to follow-up (n=18) this perception was stable over time. Crisis intervention was experienced as very significant. We discuss limitations and implications of evaluating natural setting based interventions, and the relation between psychoactive substance use and psychopathology. Other data on visitor's profile and vulnerability to crisis showed inconclusive. ","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"7 2","pages":"81-100"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32954743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Opioid neonatal abstinence syndrome: controversies and implications for practice. 阿片类药物新生儿戒断综合征:争议和影响的做法。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473707666141015215141

Kim Wolff, Raul Perez-Montejano

{"title":"Opioid neonatal abstinence syndrome: controversies and implications for practice.","authors":"Kim Wolff, Raul Perez-Montejano","doi":"10.2174/1874473707666141015215141","DOIUrl":"https://doi.org/10.2174/1874473707666141015215141","url":null,"abstract":"The Opioid Neonatal Abstinence Syndrome (NAS) is a term used to describe a cluster of signs and symptoms seen in infants experiencing withdrawal from opioid drugs. Despite a substantial literature the relationship between maternal methadone dose, NAS and the method of assessment of NAS symptoms has not been agreed. The following review will address current and historical controversies surrounding these issues and will examine the evidence concerned with the evaluation of neonates exposed to methadone in utero. The key findings are as follows: A variety of NAS scales are used to assess the severity of neonatal withdrawal symptoms including locally adapted validated tools. Inconsistencies in the use of NAS scales have included the timing, duration and frequency of administration; the degree to which observers were trained to reliability; the use of NAS scales designed for term neonates to assess pre-term neonates who may have a qualitatively different expression of abstinence symptoms and; the research setting in which the tool was administered. There is a lack of research investigating the observant bias' effect upon scoring NAS, the basis for treatment decisions and the influence of concomitant maternal use of non-opioid drugs late in pregnancy. We also discuss the implications of the lack of recognition of NAS symptoms leading to possible under reporting and inappropriate, early neonatal discharge from hospital. In addition, this paper also discusses the merits and problems of conducting research in this area and highlights gaps in our knowledge and areas for further research. ","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"7 1","pages":"44-58"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874473707666141015215141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32753261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Driving while hungover: the necessity of biomarkers of the alcohol hangover state. 醉驾:酒精宿醉状态生物标志物的必要性。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/187447370701141117112550

Joris C Verster, Aurora J A E van de Loo, Luke A Downey

引用次数: 2

Psilocybin-occasioned mystical experiences in the treatment of tobacco addiction. 裸盖菇碱引起的治疗烟草成瘾的神秘体验。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473708666150107121331

Albert Garcia-Romeu, Roland R Griffiths, Matthew W Johnson

{"title":"Psilocybin-occasioned mystical experiences in the treatment of tobacco addiction.","authors":"Albert Garcia-Romeu, Roland R Griffiths, Matthew W Johnson","doi":"10.2174/1874473708666150107121331","DOIUrl":"https://doi.org/10.2174/1874473708666150107121331","url":null,"abstract":"Psilocybin-occasioned mystical experiences have been linked to persisting effects in healthy volunteers including positive changes in behavior, attitudes, and values, and increases in the personality domain of openness. In an open-label pilot-study of psilocybin-facilitated smoking addiction treatment, 15 smokers received 2 or 3 doses of psilocybin in the context of cognitive behavioral therapy (CBT) for smoking cessation. Twelve of 15 participants (80%) demonstrated biologically verified smoking abstinence at 6-month follow-up. Participants who were abstinent at 6 months (n=12) were compared to participants still smoking at 6 months (n=3) on measures of subjective effects of psilocybin. Abstainers scored significantly higher on a measure of psilocybin-occasioned mystical experience. No significant differences in general intensity of drug effects were found between groups, suggesting that mystical-type subjective effects, rather than overall intensity of drug effects, were responsible for smoking cessation. Nine of 15 participants (60%) met criteria for \"complete\" mystical experience. Smoking cessation outcomes were significantly correlated with measures of mystical experience on session days, as well as retrospective ratings of personal meaning and spiritual significance of psilocybin sessions. These results suggest a mediating role of mystical experience in psychedelic-facilitated addiction treatment. ","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"7 3","pages":"157-64"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342293/pdf/nihms-648744.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32954739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 324

A review of lysergic acid diethylamide (LSD) in the treatment of addictions: historical perspectives and future prospects. 麦角酸二乙胺(LSD)治疗成瘾的回顾:历史观点和未来展望。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473708666150107120522

Mitchell B Liester

引用次数: 28

Older adults prescribed methadone: a review of the literature across the life span from opiate initiation to methadone maintenance treatment. 老年人处方美沙酮:回顾整个生命周期从阿片类药物开始到美沙酮维持治疗的文献。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473708666150107151010

Nick Doukas

引用次数: 3

Cannabis concerns: increased potency, availability and synthetic analogues. 大麻问题:增强效力、可获得性和合成类似物。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473708666150113165140

Luke A Downey, Joris C Verster

{"title":"Cannabis concerns: increased potency, availability and synthetic analogues.","authors":"Luke A Downey, Joris C Verster","doi":"10.2174/1874473708666150113165140","DOIUrl":"https://doi.org/10.2174/1874473708666150113165140","url":null,"abstract":"Over the past 10 to 15 years, the evidence concerning the consequences of cannabis smoking has detailed a number of negative health outcomes. Over the same period, a wide variety of alternative cannabis products (synthetic cannabis and cannabis extracts) have been developed and consumed for a variety of purposes. Whilst the impact of cannabis smoking on behavior in the short-term, and the psychiatric, behavioral, physiological effects of extended usage of cannabis in the longer term have been observed to produce a number of societally and individually concerning outcomes; consumption of cannabis recreationally, continues. Despite cannabis being considered a relatively innocuous recreational drug, current evidence suggests it can adversely impact mental health. Sustained use of cannabis has been shown to significantly increase the risk of developing schizophrenia and other psychiatric disorders (Szoke et al. 2014). Possibly more concerning, the legalization of cannabis in some countries, the approval of cannabis products for usage to treat symptoms associated with medical conditions, and the development of synthetic cannabinoid products provides increased avenues for people to expose themselves to cannabis and its psychoactive effects.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"7 2","pages":"67-8"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874473708666150113165140","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32971406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Introduction to 'beneficial effects of psychedelics with a special focus on addictions'. 介绍“迷幻药的有益作用，特别关注上瘾”。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/187447370703150220182741

J. Breeksema, R. Kortekaas

引用次数: 0

Introduction to 'beneficial effects of psychedelics with a special focus on addictions'. 介绍“迷幻药的有益作用，特别关注上瘾”。

Current drug abuse reviews Pub Date : 2014-01-01

Joost J Breeksema, Rudie Kortekaas

引用次数: 0

Treatments for co-occurring depression and substance use in young people: a systematic review. 年轻人并发抑郁症和药物使用的治疗:系统综述。

Current drug abuse reviews Pub Date : 2014-01-01 DOI: 10.2174/1874473707666141015220608

Mark Deady, Maree Teesson, Frances J Kay-Lambkin

{"title":"Treatments for co-occurring depression and substance use in young people: a systematic review.","authors":"Mark Deady, Maree Teesson, Frances J Kay-Lambkin","doi":"10.2174/1874473707666141015220608","DOIUrl":"https://doi.org/10.2174/1874473707666141015220608","url":null,"abstract":"Background: Depression and problematic substance use represent two of the major social and health problems facing young people internationally. Frequently, these conditions co-occur and this co-occurrence is associated with greater functional impact, poorer treatment outcomes, and increased costs to both society and the individual.Objective: This review aims to identify peer-reviewed published trials of interventions for co-occurring substance use and depression delivered to young people, describe these interventions, and critique the methodological quality of the studies.Method: Eleven electronic databases were searched. The reference lists of relevant review papers were searched manually for additional studies not identified by the electronic database search.Results: Initially, 1,976 studies were identified, of which 22 were classified as trial studies of youth-based treatment interventions for co-occurring substance use and depression. Ten of these studies met criteria for review. The majority (60%) utilized a pharmacotherapy component, but found it to be generally no better than placebo when both groups received adjunct counselling. METHODological quality of studies varied.Conclusions: There is a dearth of trials of interventions for co-occurring depression and substance use disorders in young people. The limited data available is promising regarding the overall effectiveness of a psychological counselling approach. Given the importance of early intervention, and the difficulties faced when engaging youth in treatment, there is a need for further focused effort amongst this group. This may require more innovative techniques in intervention design and implementation. Recent advances in Internet- and mobile phone-based therapies present a potential avenue for further research.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"7 1","pages":"3-17"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874473707666141015220608","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32752837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13