Current drug abuse reviews最新文献

Preface. 前言。

Current drug abuse reviews Pub Date : 2018-06-11 DOI: 10.2174/187447371001180611082005

R. Dinis-Oliveira

引用次数: 0

Meet Our Editor-in-Chief 认识我们的总编辑

Current drug abuse reviews Pub Date : 2018-06-11 DOI: 10.2174/187447371001180611081833

R. Dinis-Oliveira

引用次数: 0

Proceeding of the 8th Alcohol Hangover Research Group Meeting. 第八届酒精宿醉研究小组会议纪要。

Current drug abuse reviews Pub Date : 2017-05-17 DOI: 10.2174/1874473709666161229121527

M. Mackus, S. Adams, A. Barzilay, S. Benson, Lauren E. Blau, J. Iversen, Sean J Johnson, A. Keshavarzian, A. Scholey, Gordon S Smith, Constantine J. Trela, V. Vatsalya, J. Verster

{"title":"Proceeding of the 8th Alcohol Hangover Research Group Meeting.","authors":"M. Mackus, S. Adams, A. Barzilay, S. Benson, Lauren E. Blau, J. Iversen, Sean J Johnson, A. Keshavarzian, A. Scholey, Gordon S Smith, Constantine J. Trela, V. Vatsalya, J. Verster","doi":"10.2174/1874473709666161229121527","DOIUrl":"https://doi.org/10.2174/1874473709666161229121527","url":null,"abstract":"Alcohol hangover is one of the most commonly experienced consequences of alcohol consumption. An alcohol hangover develops as the blood alcohol concentrations (BAC) approaches zero, and is characterized by a general feeling of misery. More insight into the pathology of an alcohol hangover needs to be gained, in order to enhance the understanding of the area, and as a potential contribution to the innovation of a preventative or hangover curing treatment. The Alcohol Hangover Research Group (AHRG) was founded to support the area of alcohol hangover. This proceeding describes the latest findings in the area of alcohol hangovers, and future research plans, discussed at the 8th Alcohol Hangover Research Group meeting, held on June 25, 2016, New Orleans, USA. Novel insight in potential causes, consequences, and treatment of alcohol hangover were revealed during the meeting, as well as further research plans to examine biomarkers of recent alcohol consumption, immune functioning, alcohol metabolism, and potential treatments.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"15 1","pages":"106-112"},"PeriodicalIF":0.0,"publicationDate":"2017-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76916272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

A Review of the Physiological Factors Associated with Alcohol Hangover. 与酒精宿醉相关的生理因素综述。

Current drug abuse reviews Pub Date : 2017-05-17 DOI: 10.2174/1874473710666170207152933

C. Tipple, S. Benson, A. Scholey

引用次数: 29

Midazolam Plus Haloperidol as Adjuvant Analgesics to Morphine in Opium Dependent Patients: A Randomized Clinical Trial. 咪达唑仑加氟哌啶醇作为鸦片依赖患者吗啡辅助镇痛药:一项随机临床试验。

Current drug abuse reviews Pub Date : 2017-05-17 DOI: 10.2174/1874473710666170106122455

M. Afzalimoghaddam, Maryam Edalatifard, A. Nejati, M. Momeni, N. Isavi, E. Karimialavijeh

{"title":"Midazolam Plus Haloperidol as Adjuvant Analgesics to Morphine in Opium Dependent Patients: A Randomized Clinical Trial.","authors":"M. Afzalimoghaddam, Maryam Edalatifard, A. Nejati, M. Momeni, N. Isavi, E. Karimialavijeh","doi":"10.2174/1874473710666170106122455","DOIUrl":"https://doi.org/10.2174/1874473710666170106122455","url":null,"abstract":"BACKGROUND\u0000Tolerance to opioids among opium-dependent patients creates obstacles for proper pain management of these patients in the emergency department (ED). The aim of the present study was to investigate the efficacy of intramuscular (IM) haloperidol plus midazolam on morphine analgesia among opium-dependent patients.\u0000\u0000\u0000METHODS\u0000Opium-dependent adults who were admitted to the ED for new-onset severe pain in the limbs or abdomen (within 24 hours of admission and a pain score of over six, using a numerical rating scale [NRS]) were recruited. Participants were randomly assigned into two groups. Group A received morphine 0.05 mg/kg intravenously (IV) and a mixture of midazolam 2.5 mg and haloperidol 2.5 mg (diluted in 5 cc of distilled water, IM); group B received morphine 0.05 mg/kg IV and distilled water 5 cc, IM. Measured outcomes were related to: 1) pain intensity; 2) total doses of morphine; 3) changes in hemodynamic status and level of consciousness of patients. NRS scores (zero to 10) before and one, three and six hours following intervention, as well as total doses of morphine, were recorded.\u0000\u0000\u0000RESULTS\u0000We recruited 68 males (78.16%) and 19 females (21.83%). The mean age was 38.28±6.59 years. The pain score in group A declined more rapidly over six hours than that in group B. Moreover, as compared to group B, the amount of morphine use decreased significantly in group A.\u0000\u0000\u0000CONCLUSION\u0000Based on the present data, adding haloperidol plus midazolam to morphine for pain management improved pain scores and lowered morphine consumption among opium-dependent patients.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"6 1","pages":"142-147"},"PeriodicalIF":0.0,"publicationDate":"2017-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82129746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Cultivating a Trauma Awareness Culture in the Addictions. 在成瘾中培养创伤意识文化。

Current drug abuse reviews Pub Date : 2017-05-17 DOI: 10.2174/1874473710666170111102835

E. Missouridou

{"title":"Cultivating a Trauma Awareness Culture in the Addictions.","authors":"E. Missouridou","doi":"10.2174/1874473710666170111102835","DOIUrl":"https://doi.org/10.2174/1874473710666170111102835","url":null,"abstract":"BACKGROUND\u0000Research evidence points to the high prevalence of trauma exposure and post traumatic stress among addicted individuals, their families and the professionals responsible for their treatment.\u0000\u0000\u0000OBJECTIVE\u0000The purpose of this review is to enhance understanding of the continuing effects of trauma and its impact on the lives of people with addiction problems as well as on the professionals who strive to provide support and care for them.\u0000\u0000\u0000METHOD\u0000Review of twenty eight articles on traumatic experiences in individuals and families facing addiction problems as well as on traumatic stress in addiction professionals. Eligibility criteria were: publication in a peer-reviewed journal dating from 1990 to present; articles written in the English language; quantitative or qualitative design aiming to explore the lived experience of trauma and the recovery process from it.\u0000\u0000\u0000RESULTS\u0000It is argued that for service providers to be able to help patients restore purpose and meaning in the recovery process, it is important to be aware of the trauma dynamics implicated in the long history of the addiction problems. Professionals' difficulty to process their emotions may lead to disengagement or overinvolvement and the adoption of maladaptive roles. Strong and unexpected emotional reactions in the professional may be a clue to the presence of masked trauma.\u0000\u0000\u0000CONCLUSION\u0000Ongoing training on trauma dynamics, self-care and clinical supervision may deepen professionals' understanding of the impact of trauma on their work culture and protect them from the risk of secondary traumatic stress.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"57 1","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2017-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89109990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Development of a Definition for the Alcohol Hangover: Consumer Descriptions and Expert Consensus. 酒精宿醉定义的发展:消费者描述和专家共识。

Current drug abuse reviews Pub Date : 2017-05-17 DOI: 10.2174/1874473710666170216125822

M. van Schrojenstein Lantman, A. J. van de Loo, M. Mackus, J. Verster

引用次数: 81

Withdrawn: The Behavioral Profile of methylenedioxypyrovalerone (MDPV) and α-pyrrolidinopentiophenone (PVP) - A Systematic Review. 撤回：亚甲二氧基吡咯戊酮（MDPV）和α-吡咯烷酮（PVP）的行为特征--系统综述。

Current drug abuse reviews Pub Date : 2017-03-21 DOI: 10.2174/1874473710666170321122226

Cornel N Stanciu, Thomas M Penders, Samantha A Gnanasegaram, Elvin Pirapakaran, Juvraj S Padda, Jeeven S Padda

引用次数: 0

Cannabis: An Overview of its Adverse Acute and Chronic Effects and its Implications. 大麻:概述其不利的急性和慢性影响及其影响。

Current drug abuse reviews Pub Date : 2017-01-01 DOI: 10.2174/1874473710666170712113042

Talitha C Ford, Amie C Hayley, Luke A Downey, Andrew C Parrott

{"title":"Cannabis: An Overview of its Adverse Acute and Chronic Effects and its Implications.","authors":"Talitha C Ford, Amie C Hayley, Luke A Downey, Andrew C Parrott","doi":"10.2174/1874473710666170712113042","DOIUrl":"https://doi.org/10.2174/1874473710666170712113042","url":null,"abstract":"In many communities, cannabis is perceived as a low-risk drug, leading to political lobbying to decriminalise its use. Acute and chronic cannabis use has been shown to be harmful to several aspects of psychological and physical health, such as mood states, psychiatric outcomes, neurocognition, driving and general health. Furthermore, cannabis is highly addictive, and the adverse effects of withdrawal can lead to regular use. These in turn have adverse implications for public safety and health expenditure. Although the cannabinoid cannabidiol (CBD) has been shown to have positive health outcomes with its antioxidant, anticonvulsant, anti-inflammatory and neuroprotective properties, high-potency cannabis is particularly damaging due to its high tetrahydrocannabinol (THC), low CDB concentration. It is this high-potency substance that is readily available recreationally. While pharmaceutical initiatives continue to investigate the medical benefits of CDB, \"medicinal cannabis\" still contains damaging levels of THC. Altogether, we argue there is insufficient evidence to support the safety of cannabis and its subsequent legalisation for recreational use. Furthermore, its use for medicinal purposes should be done with care. We argue that the public conversation for the legalisation of cannabis must include scientific evidence for its adverse effects.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"10 1","pages":"6-18"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35170526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 51

High Prevalence of Abandoned Needlesticks from Injecting Drug Users in Milton Keynes, UK: Analysing Access to Needle Exchange Centres and Drug Dependency Services. 英国米尔顿凯恩斯注射吸毒者丢弃针头的高流行率:分析针头交换中心和药物依赖服务的可及性。

Current drug abuse reviews Pub Date : 2017-01-01 DOI: 10.2174/1874473711666180418164130

Dushyant Mital, Steve Conway, Joanne Trueman

{"title":"High Prevalence of Abandoned Needlesticks from Injecting Drug Users in Milton Keynes, UK: Analysing Access to Needle Exchange Centres and Drug Dependency Services.","authors":"Dushyant Mital, Steve Conway, Joanne Trueman","doi":"10.2174/1874473711666180418164130","DOIUrl":"https://doi.org/10.2174/1874473711666180418164130","url":null,"abstract":"Background: In 2015, Milton Keynes (MK) Council waste management team shows an increase in the numbers of abandoned used needles being found across MK. MK is an area of high Human Immunodeficiency Virus (HIV) prevalence and high Hepatitis C (HCV) in People Who Inject Drugs (PWID), the overriding concern was for the safety of the public.Methods: Analysis of data collection to understand the scale and spread of the problem, preventing/ reducing the incidence of abandoned needles and looking at access to the designated Drug Dependency Unit (DDU) and the Blood Borne Virus (BBV) service. Through data mapping, hotspot areas of used needles abandonment were analysed.Results: Peak needle stick finds were in March and June 2015 mainly in areas of social deprivation and marginalisation where designated needle exchange points were identified. 174 reports of abandoned needles were reported between January 2015 and November 2015 with a total of 2379 individual needles. 87% of the total numbers of needles were found in just 8 estates.Conclusion: Tackling the issue of abandoned needles effectively should be done through a targeted, multi-agency approach. Reductions in needlestick abandonment can be strengthened through improving access to needle exchange points, DDU and BBV services, delivering high-quality harm reduction interventions and using data mapping in order to identify and target hot spot areas.","PeriodicalId":72730,"journal":{"name":"Current drug abuse reviews","volume":"10 1","pages":"76-80"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36061513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1