Clinical laboratory science : journal of the American Society for Medical Technology最新文献

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The CF Quantum Sweat Test: Not Ready for Clinical Use CF量子汗液测试:尚未准备好用于临床
Michael Rock, Vicky LeGrys
{"title":"The CF Quantum Sweat Test: Not Ready for Clinical Use","authors":"Michael Rock, Vicky LeGrys","doi":"10.29074/ascls.2019002105","DOIUrl":"https://doi.org/10.29074/ascls.2019002105","url":null,"abstract":"<h3>ABSTRACT</h3> The cystic fibrosis (CF) Quantum test (CFQT) showed promise in a previous pilot study; however, there was greater imprecision in one patch lot. Following the pilot study, the manufacturer changed their fabricating procedures. Participants with previously diagnosed CF or participants who required a sweat test for clinical reasons were invited to undergo the CFQT research test and a conventional sweat test (Macroduct collection and chloride analysis via the ChloroChek chloridometer). Previously diagnosed CF (<i>n</i> = 41) and CF transmembrane regulator–related metabolic syndrome/CF screen positive inconclusive diagnosis (<i>n</i> = 3) patients and patients who required a sweat test for clinical indications (<i>n</i> = 22) were recruited to have bilateral CFQT along with the Macroduct test performed on the same day. Pairs of data from each test were plotted as a correlation graph, bias plot, and Bland Altman plot. Coefficient of variation (CV) between extremities and quantity-not-sufficient (QNS) rates for both tests were calculated. The CV between left and right extremities was greater in the CFQT (9.5%) compared with the Macroduct (4.8%). The QNS rates of the two tests were comparable (CFQT, 6.8%; Macroduct, 6.0%). There was greater imprecision with the CFQT results. The diagnostic agreement between the two tests was 100% positive percent agreement (95% confidence interval [CI], 90%–100%), 100% negative percent agreement (95% CI, 80%–100%), 67% intermediate percent agreement (95% CI, 30%–80%), and 92% overall percent agreement (95% CI, 80%–100%). This follow-up study demonstrated that the CFQT is not analytically nor diagnostically reliable (Clinicaltrials.gov identifier NCT01345617).","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"331 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136119697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Efficacy and Acceptance of Brief Intentional Teachings to Encourage Success 鼓励成功的简短的有意教导的有效性和接受度
Scott Moore
{"title":"The Efficacy and Acceptance of Brief Intentional Teachings to Encourage Success","authors":"Scott Moore","doi":"10.29074/ascls.2019001560","DOIUrl":"https://doi.org/10.29074/ascls.2019001560","url":null,"abstract":"<h3>ABSTRACT</h3> Students in medical laboratory sciences occasionally struggle in lecture to acquire the knowledge covered in the objectives. After review of the ASCLS Body of Knowledge, 9 clearly stated objectives in acid-base studies were distilled, and 2 Brief Intentional Teachings to Encourage Success (BITES) were created. These BITES are a form of microlearning, wherein students take 10- to 20-minute chunks of time to learn a brief topic. Five objectives are defined, and review questions are asked to stimulate active recall and retrieval. At the end, 3 questions are asked that require application of the knowledge gained over the previous 10–20 minutes. Three surveys were given to all students at different points in time to assess the efficacy and acceptance of BITES; Post-lecture (Pre-BITES) Questionnaire (PLQ), Post-BITES Questionnaire (PBQ), and Post–3-month Questionnaire (P3Q). In comparing the PLQ and the PBQ, 8 correct answers were recalled more often in the PBQ, and 3 correct answers were recalled more often in the PLQ. All correct answers were recalled more often in the P3Q than the PLQ. The question, “I enjoyed these BITES,” was answered with 1 “no” and 5 “yes” and received the following scores: 0 answered 1, 0 answered 2, 3 answered 3, 8 answered 4, and 11 answered 5. The question, “I preferred learning with…”, indicated that all students but 1 preferred BITES over lecture. As we continue to master our craft of teaching, we learn that MLS students prefer learning with BITES in a traditional lecture-based classroom and that durable learning was accomplished over 3 months with their use. Further studies are required to see if BITES improve student engagement.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136119698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of University of Washington Medical Laboratory Science Clinical Rotation Length and Student Performance 华盛顿大学医学实验室科学临床轮转时间和学生表现的评估
Patty Callahan
{"title":"Evaluation of University of Washington Medical Laboratory Science Clinical Rotation Length and Student Performance","authors":"Patty Callahan","doi":"10.29074/ascls.2019001537","DOIUrl":"https://doi.org/10.29074/ascls.2019001537","url":null,"abstract":"<h3>ABSTRACT</h3> <h3>BACKGROUND:</h3> Local changes and needs in blood-bank operations allowed us to increase our medical laboratory science (MLS) blood-bank rotation to 4 weeks by reducing rotation length for clinical chemistry, microbiology, and hematology from 6 weeks to 5 weeks. We evaluated the impact of this change on American Society for Clinical Pathology Board of Certification (BOC) examination performance. <h3>METHODS:</h3> We compared BOC scores for 119 MLS graduates with 6-week clinical rotation lengths in chemistry, microbiology, and hematology (2009–2013) and 127 MLS graduates with 5-week rotation lengths in these disciplines (2014–2018). We evaluated first-time pass rates, overall certification scores, specific discipline scores, and student rotation length satisfaction surveys. <h3>RESULTS:</h3> Mean ± SD overall BOC scores for 6-week rotations (547 ± 74) were not significantly different from overall BOC scores for 5-week rotations. Similarly, there was no significant effect on BOC scores for chemistry, microbiology, or hematology. The mean first-time pass rate for 6-week rotations was 97% compared with 96% for 5-week rotations. Student satisfaction surveys received from 282 out of 307 (92%) students during 2014–2018 indicated that the 5-week rotation length was adequate. <h3>CONCLUSION:</h3> Reducing rotation length had no detrimental effect on BOC scores or student satisfaction. These findings allowed us to respond to changing patterns in laboratory medicine. Beginning in 2018, students will receive a 1-week rotation in 1 of 6 molecular diagnostic testing laboratories, including hematopathology, virology, microbiology, genetics, and blood-bank. These rotations may be expanded as laboratory testing moves in this direction.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using a Game-based Learning Platform to Increase Student Engagement in the Classroom 使用基于游戏的学习平台来提高学生在课堂上的参与度
Melissa Jamerson
{"title":"Using a Game-based Learning Platform to Increase Student Engagement in the Classroom","authors":"Melissa Jamerson","doi":"10.29074/ascls.2019001594","DOIUrl":"https://doi.org/10.29074/ascls.2019001594","url":null,"abstract":"<h3>ABSTRACT</h3> The Department of Clinical Laboratory Sciences at Virginia Commonwealth University incorporated the use of a game-based learning platform into a junior-level Immunology course. The primary goal of this addition was to increase student engagement during review sessions. In previous years, each Immunology class was started with a review of material from an earlier lecture. The review consisted of short-answer and multiple-choice questions as a means to highlight important concepts and allow additional opportunities for students to ask questions. During these review periods, it was observed that class participation ranged from 3%–20%. Additionally, those who did participated were the same students in each class period. The incorporation of the game-based learning platform into review sessions involved asking review questions in multiple-choice format with 30 seconds of time for students to answer after each question was asked. This new format resulted in class participation increasing to 95%–100%. Review of student answers also allowed the instructor to determine which areas the students needed additional assistance with before exams. Student feedback indicated that they enjoyed the ability to be anonymous when answering questions while still getting immediate feedback. This new review format will be utilized in additional courses, specifically Immunohematology. Furthermore, this game-based platform will be used to review material with senior students in their advanced senior-level courses.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective Marketing Strategies for a Medical Laboratory Science Program 医学实验室科学项目的有效营销策略
Kendal Beazer, Kenton Cummins
{"title":"Effective Marketing Strategies for a Medical Laboratory Science Program","authors":"Kendal Beazer, Kenton Cummins","doi":"10.29074/ascls.2019002154","DOIUrl":"https://doi.org/10.29074/ascls.2019002154","url":null,"abstract":"","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethics in Research 研究伦理
Bernard C. Beins
{"title":"Ethics in Research","authors":"Bernard C. Beins","doi":"10.1017/9781108550734.003","DOIUrl":"https://doi.org/10.1017/9781108550734.003","url":null,"abstract":"This chapter studies ethics in research. Ethics play an important role in scientific inquiry, beyond cases of plagiarism, fraud, and misconduct. Importantly, there is a difference between ethical research and ethical researchers. While principles of ethics in research stem mostly from the biomedical field, they have also been adapted to apply to the social sciences. These principles are generally addressed through three common principles: voluntary participation, informed consent, and confidentiality. Researchers themselves must be wary of a number of other factors that can influence their project and role, such as the supervision of students, or other situations where there is a relationship of authority. Similarly, researchers must be careful not to make misrepresentations to subjects about the project or the related risks, or fail to disclose any conflict of interest. Researchers must take steps to ensure their neutrality so that no preconceptions or personal bias can risk influencing the results or subjects. The chapter then looks at ethics review boards and the emergent ethical issues.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/9781108550734.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56920324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 192
Evaluation of Diverse Health Professionals' Learning Experience in a Continuing Education Activity for Quality Practices in Molecular Genetic Testing. 不同卫生专业人员在分子基因检测质量实践继续教育活动中的学习经验评估。
Bin Chen, Shahram Shahangian, Thomas H Taylor, Ajay Yesupriya, Carol Greene, Valerie J Curry, Barbara Zehnbauer
{"title":"Evaluation of Diverse Health Professionals' Learning Experience in a Continuing Education Activity for Quality Practices in Molecular Genetic Testing.","authors":"Bin Chen,&nbsp;Shahram Shahangian,&nbsp;Thomas H Taylor,&nbsp;Ajay Yesupriya,&nbsp;Carol Greene,&nbsp;Valerie J Curry,&nbsp;Barbara Zehnbauer","doi":"10.29074/ascls.29.4.200","DOIUrl":"https://doi.org/10.29074/ascls.29.4.200","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted to evaluate the responses of 3,265 health professionals who took a continuing education (CE) activity during June 2009 - April 2012 for a comprehensive set of good laboratory practice recommendations for molecular genetic testing.</p><p><strong>Design: </strong>Participants completed an evaluation questionnaire as part of the CE activity. Responses were summarized to assess the participants' learning outcomes and commitment to applying the knowledge gained.</p><p><strong>Participants: </strong>Participants included nurses (47%), laboratory professionals (18%), physicians (14%), health educators (4%), public health professionals (2%), office staff (1%), and other health professionals (10%).</p><p><strong>Results: </strong>Only 32% of all participants correctly answered all 12 open-book knowledge-check questions, ranging from 4 to 42% among the different professional groups (<i>P</i><0.0001). However, over 80% of all participants expressed confidence in describing the practice recommendations, and 75% indicated the recommendations would improve the quality of their practice. Developing health education materials and local practice guidelines represented the common areas in which participants planned to use the knowledge gained (49% and 18% of all participants, respectively).</p><p><strong>Conclusion: </strong>Despite perceived self-efficacy in most participants, as high as 68% did not fully use the learning materials provided to answer the knowledge-check questions. These findings suggest the need for improved CE activities that motivate effective learning and address the specific needs of different health professions.</p>","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"29 4","pages":"200-211"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477687/pdf/nihms-1022258.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37184903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A survey study of benefits and limitations of using CellaVision DM96 for peripheral blood differentials. 使用CellaVision DM96检测外周血差异的益处和局限性的调查研究。
Sandra J VanVranken, Emily S Patterson, Sally V Rudmann, Kathy V Waller
{"title":"A survey study of benefits and limitations of using CellaVision DM96 for peripheral blood differentials.","authors":"Sandra J VanVranken,&nbsp;Emily S Patterson,&nbsp;Sally V Rudmann,&nbsp;Kathy V Waller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In most clinical laboratories, hematologists rely on the microscopic analysis of stained blood films to accurately classify cells, aiding in the diagnosis and monitoring of a variety of disorders and conditions. Use of the microscope, although considered the gold standard in performing white blood cell differentials, presents a variety of limitations Digital image technology can facilitate a variety of essential job functions in clinical hematology such as: consulting with colleagues, improving training, referencing an abnormal cell, and utilizing archived images for quality assurance and competency assessment. A questionnaire was developed to survey medical laboratory professionals about their perceptions regarding the benefits and limitations for using digital images in clinical hematology. The questionnaire was sent in March 2012 to an entire list of 81 current CellaVision DM96 (CellaVision AB, Sweden) consumers. A response rate of 46% was obtained. Background information on participants, 5-point Likert scale averages, percentage agreement (strongly agree and agree), and disagreement (strongly disagree and disagree) were calculated and analyzed. The benefits of using the CellaVision DM96 rated the strongest by respondents included: decreased eyestrain, consistency among patient results and advantages in training personnel. Respondents reported notable limitations as being: restrictions with accurately estimating platelets and red cell morphology. Digital image software is currently being utilized in preclinical and clinical hematology and offers potential benefits. With upgrades in slide scanning features and improved capabilities to view platelet and red cell morphology, a transition to digital image technology from the conventional method for performing peripheral blood cell differentials is possible.</p>","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"27 1","pages":"32-9"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32207704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Focus: Next generation sequencing. Introduction. 重点:下一代测序。介绍。
Deborah Josko
{"title":"Focus: Next generation sequencing. Introduction.","authors":"Deborah Josko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"27 3","pages":"170-72"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32665699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platforms. 平台。
Deborah Josko
{"title":"Platforms.","authors":"Deborah Josko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The advent of DNA sequencing technologies and the various applications that can be performed will have a dramatic effect on medicine and healthcare in the near future. There are several DNA sequencing platforms available on the market for research and clinical use. Based on the medical laboratory scientist or researcher's needs and taking into consideration laboratory space and budget, one can chose which platform will be beneficial to their institution and their patient population. Although some of the instrument costs seem high, diagnosing a patient quickly and accurately will save hospitals money with fewer hospital stays and targeted treatment based on an individual's genetic make-up. By determining the type of disease an individual has, based on the mutations present or having the ability to prescribe the appropriate antimicrobials based on the knowledge of the organism's resistance patterns, the clinician will be better able to treat and diagnose a patient which ultimately will improve patient outcomes and prognosis.</p>","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"27 3","pages":"173-8"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32666694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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