Clinical laboratory science : journal of the American Society for Medical Technology最新文献

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Virtual Learning: The Development of Case Study Based Lab Simulation in the Clinical Laboratory Science Undergraduate Curriculum 虚拟学习:基于案例研究的实验室模拟在临床检验科学本科课程中的发展
Stephanie Cochrane
{"title":"Virtual Learning: The Development of Case Study Based Lab Simulation in the Clinical Laboratory Science Undergraduate Curriculum","authors":"Stephanie Cochrane","doi":"10.29074/ascls.2019001552","DOIUrl":"https://doi.org/10.29074/ascls.2019001552","url":null,"abstract":"","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136119699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathophysiology of Thrombotic Thrombocytopenia Purpura 血栓性血小板减少性紫癜的病理生理学
Larry Smith
{"title":"Pathophysiology of Thrombotic Thrombocytopenia Purpura","authors":"Larry Smith","doi":"10.29074/ascls.2020002261","DOIUrl":"https://doi.org/10.29074/ascls.2020002261","url":null,"abstract":"<h3>ABSTRACT</h3> This review describes classic thrombotic thrombocytopenic purpura (TTP), discusses the pathogenesis of acquired and congenital TTP, describes clinical and laboratory manifestations observed in patients, and lists options for treating patients with TTP. TTP is a rare hematologic disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia. It results from a congenital or acquired deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13), in plasma. Most cases are caused by an autoimmune mechanism that interferes with ADAMTS-13; however, rare inherited forms of TTP have been described (e.g., Upshaw-Schulman syndrome). It is still considered a life-threatening disease with a mortality rate of 10%–20%. Severe deficiency of ADAMTS-13 (<10%) is most often associated with congenital TTP. Although TTP is a serious hematologic emergency that is almost always fatal in untreated cases, an understanding of its pathophysiology can lead to successful treatment strategies, resulting in improved patient care and outcomes.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136120051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilization of Apple iPads in Student Clinical Rotations to Improve Safety and Streamline Information Access 在学生临床轮转中使用苹果ipad提高安全性和简化信息获取
Jenica L. Harrison, Lisa Perkins, Teresa Nadder
{"title":"Utilization of Apple iPads in Student Clinical Rotations to Improve Safety and Streamline Information Access","authors":"Jenica L. Harrison, Lisa Perkins, Teresa Nadder","doi":"10.29074/ascls.2020002436","DOIUrl":"https://doi.org/10.29074/ascls.2020002436","url":null,"abstract":"<h3>ABSTRACT</h3> American Society for Microbiology Guidelines for Biosafety in Teaching Laboratories (2012) state that educators must use best practices to minimize risk of biohazard contamination to students. Integrating mobile digital devices into medical laboratory science (MLS) programs’ clinical training is potentially one means of reducing this risk. The purpose of this pilot project was to ascertain attitudes from students and clinical educators on using mobile devices as a laboratory benchside educational tool during clinical rotations as a novel alternative to paper materials. In this study, 3 senior-level MLS students used Apple iPads in concert with Google Drive in lieu of paper manuals during Hematology and Transfusion Medicine clinical rotations at Virginia Commonwealth University Health (VCUH). Two VCUH clinical educators from these laboratories also participated. All participants were trained on usage and access of electronic material on the iPads as well as proper cleaning of the devices. Prestudy surveys were used to assess attitudes toward mobile devices. Focus groups, for students and clinical educators, separately, were conducted after completion of the clinical rotations. The results of the study indicate that advantages of employing mobile devices include improvement of safety by eliminating transfer of paper worksheets from laboratory to the outside, ability to electronically monitor students’ progress through clinical laboratory rotations, and ease of accessibility to electronic references at the benchside. Information gained from this pilot study implies that mobile devices can be used to decrease contamination risk while serving as a state-of-the-art educational tool on the laboratory benchside. Potential applications of mobile devices within the clinical laboratory include: (1) recording and tracking instrument maintenance, (2) tracking personnel training and competences, and (3) tracking reagent inventory.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovative Approach to Moderating Risk of Nosocomial Infection During Anesthesia 降低麻醉期间医院感染风险的创新方法
Thomas Corey Davis, Beverly George Gay, Melissa Jamerson, Sarah A. Marrs, Ronsard Daniel, Chuck J. Biddle
{"title":"Innovative Approach to Moderating Risk of Nosocomial Infection During Anesthesia","authors":"Thomas Corey Davis, Beverly George Gay, Melissa Jamerson, Sarah A. Marrs, Ronsard Daniel, Chuck J. Biddle","doi":"10.29074/ascls.2020002246","DOIUrl":"https://doi.org/10.29074/ascls.2020002246","url":null,"abstract":"<h3>ABSTRACT</h3> Infection control concerns abound in the surgical anesthesia workstation, placing patients and providers at significant, documented risk because of many factors, including provider hand hygiene lapses, equipment design and complexity, and challenging disinfection. A trial was performed to mitigate cross-contamination involving 30 general anesthesia surgical operations matched 1:1 as control (no intervention) or intervention group (condom-like barriers to 4 anesthesia workstation components that are frequently touched and contaminated and very difficult to disinfect). Wraps were removed at the end of the operation and then replaced with fresh ones before the start of the subsequent operation. Baseline culture samples were obtained prior to the first surgical operation of the day in each room and then performed on operations that followed in each room over a 3-day period. Baseline colony-forming unit density was equivalent in both conditions with total density significantly lower in the covered/wrapped (mean rank = 5.81) vs uncovered condition (mean rank = 11.19) at <i>P</i> < 0.01, <i>r</i> = −0.64. Bacterial species diversity was markedly decreased in the covered condition. The covered condition served as a barrier to contamination of apparatus elements, preventing downstream patient exposure and mitigating between-procedure disinfection need. Intervention group providers were debriefed, finding only rare, addressable concerns. This research further validates the need for routine, periodic culturing of anesthetic apparatus to reveal lapses in provider behaviors and disinfection practices.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pilot Program in Clinical Microbiology Laboratory Simulation for MLS Students MLS学生临床微生物实验室模拟试点项目
Angela Wilson
{"title":"Pilot Program in Clinical Microbiology Laboratory Simulation for MLS Students","authors":"Angela Wilson","doi":"10.29074/ascls.2019001602","DOIUrl":"https://doi.org/10.29074/ascls.2019001602","url":null,"abstract":"<h3>ABSTRACT</h3> Medical laboratory science educational programs face the challenge of placing students for clinical practica/rotations. In a nonmedical university, this has been particularly true for clinical microbiology pracetica as local health care systems centralize microbiology, serology, and molecular testing services with smaller hospitals, which house “stat labs” only. Encouraged by the success of an immunohematology simulation practicum implemented over 15 years ago, in the summer 2018 faculty piloted a clinical microbiology simulation laboratory to satisfy entry-level practical competency requirements. The pilot program consisted of 3 weeks of on-campus laboratory simulation followed by a 2-week hospital clinical experience, as opposed to 5 weeks in the clinical setting in the traditional practicum. In the laboratory simulation, students completed clinical microbiology evaluations on all clinical specimen types. Identification techniques included bench-top tests, automated identification, and antibiotic susceptibility testing. Students used rapid-kit tests and performed quality control. Upon completion of the students’ practicum final examination and the microbiology section of the comprehensive program exit examination, faculty evaluated student learning using 2-sample t-tests to establish if statistically significant differences existed in the scores achieved by students enrolled in the pilot versus the traditional model. We hypothesized that no such differences would exist. There were no statistically significant differences among the postpracticum examination results achieved by both groups (<i>P</i> < 0.05). We conclude that students had an equally valuable learning experience in both practicum models and plan to expand the on-campus simulation to alleviate clinical site shortage.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136120044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of the Laboratory’s Role in the Diagnosis and Treatment of Thrombotic Thrombocytopenic Purpura 实验室在诊断和治疗血栓性血小板减少性紫癜中的作用综述
Billie Ketelsen
{"title":"An Overview of the Laboratory’s Role in the Diagnosis and Treatment of Thrombotic Thrombocytopenic Purpura","authors":"Billie Ketelsen","doi":"10.29074/ascls.2020002253","DOIUrl":"https://doi.org/10.29074/ascls.2020002253","url":null,"abstract":"<h3>ABSTRACT</h3> Thrombotic thrombocytopenic purpura (TTP) is a multifaceted disease for a clinical laboratory with diagnosis data and treatment spread across many different laboratory sections. By encompassing results from hematology, chemistry, molecular, and coagulation sections with treatment from the transfusion medicine/blood bank section of the laboratory, clinicians are able to accurately diagnose and treat TTP.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Clinical Significance ofStaphylococcus aureusSmall Colony Variants 金黄色葡萄球菌小菌落变异的临床意义
Klara C. Keim, Isaiah K. George, Landrye Reynolds, Allie Clinton Smith
{"title":"The Clinical Significance of<i>Staphylococcus aureus</i>Small Colony Variants","authors":"Klara C. Keim, Isaiah K. George, Landrye Reynolds, Allie Clinton Smith","doi":"10.29074/ascls.2020002691","DOIUrl":"https://doi.org/10.29074/ascls.2020002691","url":null,"abstract":"<h3>ABSTRACT</h3> A burdensome, atypical phenotype of <i>Staphylococcus aureus</i> (SA) called SA small colony variants (SCVs) has been identified, which is induced because of a combination of environmental stressors, including polymicrobial interactions. SA-SCVs exhibit altered phenotypes because of metabolic dormancy caused by electron-transport deficiency, which leads to increased biofilm production and alterations to antimicrobial susceptibility. SA-SCVs typically exhibit altered colony morphology and biochemical reactions compared with wild-type SA, making them difficult to detect via routine diagnostic procedures. SA-SCVs have been found to contribute to chronic or recurrent infections, including skin and soft-tissue infections, foreign-body–associated infection, cystic fibrosis, and sepsis. There is evidence that SA-SCVs contribute to patient morbidity and mortality rates because of diagnostic difficulties and limited treatment options. New detection methods may need to be developed that can be incorporated into routine diagnostic procedures, which would allow for better assessment of specimens and introduce new considerations for management.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136120045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laboratory Findings in Hematology, Clinical Chemistry, and Urinalysis for Patients With Thrombotic Thrombocytopenic Purpura 血栓性血小板减少性紫癜患者血液学、临床化学和尿液分析的实验室结果
Kathy Doig, Susan McQuiston
{"title":"Laboratory Findings in Hematology, Clinical Chemistry, and Urinalysis for Patients With Thrombotic Thrombocytopenic Purpura","authors":"Kathy Doig, Susan McQuiston","doi":"10.29074/ascls.2020002279","DOIUrl":"https://doi.org/10.29074/ascls.2020002279","url":null,"abstract":"<h3>ABSTRACT</h3> Laboratory diagnosis of thrombotic thrombocytopenic purpura (TTP) often begins with routine laboratory tests; a complete blood count, clinical chemistry panel, and urinalysis. The classical findings may include anemia with schistocytes, thrombocytopenia, reticulocytosis or polychromasia, bilirubinemia, dark urine, and hemoglobinuria without red blood cells in the sediment. Additional findings, including decreased haptoglobin, can identify fragmentation as the cause for the hemolysis. The hemolysis in TTP arises from increased shear stress on red blood cells in arterioles and capillaries narrowed by microthrombi. Hemoglobinemia and schistocytes may generate spurious results in hematology analyzers that require correction before results can be released to the patient chart.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136119696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interprofessional Education: A Pilot for Future Collaboration 跨专业教育:未来合作的试点
Lisa Hochstein
{"title":"Interprofessional Education: A Pilot for Future Collaboration","authors":"Lisa Hochstein","doi":"10.29074/ascls.2019001610","DOIUrl":"https://doi.org/10.29074/ascls.2019001610","url":null,"abstract":"<h3>ABSTRACT</h3> Interprofessional education (IPE) has become an integral pedagogy within the St. John’s University College of Pharmacy and Health Sciences Department of Clinical Health Professions. An interprofessional case study activity was developed and incorporated into the Clinical Laboratory Sciences (CLS) and Physician Assistant (PA) programs. A pneumonia case involving aspects of patient care relevant to both programs was created. To not interfere with courses currently in progress for both programs, the event occurred during lunch hour and both programs asked for student volunteers. Ten students in total participated. Students worked together to better understand each other’s role in diagnosing the patient, emphasizing team practice. PA students illustrated techniques in history and physical examination. CLS students then led the PA students into a mock laboratory and shared examples of pneumococcal plating and microscopic isolation for diagnosis confirmation. At the conclusion of the event, students evaluated their experience. Using role perception questionnaires, CLS and PA students indicated greater perceived value for one another’s profession at activity completion. Evaluations indicated that students felt this was a worthwhile experience and that they learned a lot about each other’s role in patient care. They also indicated that they would like to have similar programs in the future.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136120049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increasing Awareness of Medical Laboratory Science through Summer Outreach Programs 通过暑期拓展计划提高医学实验室科学的意识
Lindsey Clark
{"title":"Increasing Awareness of Medical Laboratory Science through Summer Outreach Programs","authors":"Lindsey Clark","doi":"10.29074/ascls.2019001586","DOIUrl":"https://doi.org/10.29074/ascls.2019001586","url":null,"abstract":"<h3>ABSTRACT</h3> A common challenge in the medical laboratory science (MLS) profession is that it does not often receive the attention it deserves. In an effort to overcome this issue, increase awareness of MLS as a career, and expand recruitment efforts to high school students, the Department of Laboratory Sciences faculty developed a hands-on laboratory experience to be implemented into existing summer outreach programs on the University of Arkansas for Medical Sciences campus. Participants in the outreach program included 175 high school students from rural areas of the state. This experience involved participants completing a process of DNA extraction using the Bio-Rad Genes in a Bottle<sup>TM</sup> Kit and viewing a presentation highlighting the MLS profession, program prerequisites, laboratory career opportunities, and salary outlook. A post-experience survey was given to the participants with a 77% response rate. Results showed the overwhelming majority of participants enjoyed the laboratory activity. A total of 53% of survey participants indicated they did not have knowledge of the MLS profession prior to the activity, with 93% indicating the presentation and activity provided a better understanding of the field. While 24% of respondents indicated they were interested in pursuing a career in laboratory sciences, 48% would consider MLS as a steppingstone into another health care–related field. Implementing a laboratory component into existing summer programs proved to be an effective method for program outreach and recruitment among high school students. The department plans to continue offering this experience for future summer outreach opportunities.","PeriodicalId":72611,"journal":{"name":"Clinical laboratory science : journal of the American Society for Medical Technology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136121520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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