{"title":"Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death","authors":"Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong","doi":"10.1002/adrr.202500104","DOIUrl":"https://doi.org/10.1002/adrr.202500104","url":null,"abstract":"Chemotherapy and photothermal therapy (PTT) hold great potential in cancer treatment, but face challenges including low therapeutic agent penetration and insufficient photothermal effects. Therefore, it is necessary to design a nanomedicine delivery system capable of both PTT and controlled drug release. Here, a bowl‐shaped PDA@UiO‐66 nanorobot was designed for efficient loading of doxorubicin (DOX), enabling synergistic cancer cell death through combined chemotherapy and PTT. The superior photothermal‐effect bowl‐shaped Polydopamine (PDA) was synthesized using an emulsion‐induced interface anisotropic assembly method, and UiO‐66 was grown on its surface through functional groups to enhance the drug‐loading capacity. The asymmetric structure of nanorobots enables efficient self‐thermophoretic motion under Near‐infrared (NIR) irradiation. Compared to static nanorobots, NIR irradiation not only drives nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers DOX release via hyperthermia, enhancing cancer cellular uptake of DOX and thereby significantly improving the combined chemo‐photothermal therapeutic efficacy. This novel therapeutic strategy, which combines self‐propelled motion with photothermally responsive drug release, overcomes the technical limitations of decoupled motility and drug release in traditional nano‐delivery systems. It achieves precise photothermal‐controlled drug release and significantly enhances tumor cell‐killing efficiency. This approach provides an innovative strategy for developing multifunctional integrated nanodrug delivery platforms.","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adrr.202500104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147333122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang
{"title":"Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery","authors":"Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang","doi":"10.1002/adrr.202500100","DOIUrl":"https://doi.org/10.1002/adrr.202500100","url":null,"abstract":"Gut biological information, including microbiota and metabolites, shows increasing associations with diseases such as inflammatory bowel disease, obesity, and diabetes. Precise sampling and modulation of biological information have become critical in medical research, health assessments, and interventions. Although various intestinal sampling and drug delivery capsules have been developed independently, achieving multifunctional passive capsules within a swallowing size remains a challenge. Here, we have designed a dual‐functional passive capsule that integrates intestinal sampling and drug delivery capabilities through a dual‐control mechanism based on pH responsiveness and mechanical actuation and meets the standard requirements for oral ingestion (Ø10.5 mm × L26 mm). It is engineered to target specific regions of the gut, activating the sampling function in response to pH values (≥5.5). The system enables high‐throughput collection of intestinal juice (>300 μL) while effectively resisting gas interference. An integrated, spring‐driven actuation mechanism provides a sealing force exceeding 0.78 N, ensuring secure encapsulation of collected samples even under the mechanical stresses posed by high‐viscosity intestinal contents (1 × 10 6 mPa s). The capsule's dual functionality was successfully validated in‐vivo using Bama miniature pigs, demonstrating efficient, contamination‐sealed sample collection suitable for downstream sequencing analysis and highlighting its strong potential for biomedical applications.","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adrr.202500100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Advanced RoboticsPub Date : 2024-09-10DOI: 10.1080/01691864.2024.2398556
Yu Fang, José Manuel Pérez-Molerón, Luis Merino, Su-Ling Yeh, Shigeaki Nishina, Randy Gomez
{"title":"Enhancing social robot's direct gaze expression through vestibulo-ocular movements","authors":"Yu Fang, José Manuel Pérez-Molerón, Luis Merino, Su-Ling Yeh, Shigeaki Nishina, Randy Gomez","doi":"10.1080/01691864.2024.2398556","DOIUrl":"https://doi.org/10.1080/01691864.2024.2398556","url":null,"abstract":"Non-verbal communication, especially eye contact, plays a crucial role in human interaction. Integrating eye contact capabilities into robotic behavior presents challenges that require comprehensiv...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"79 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142255013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Advanced RoboticsPub Date : 2024-09-10DOI: 10.1080/01691864.2024.2394538
Taiken Shintani, Carlos Toshinori Ishi, Hiroshi Ishiguro
{"title":"Gaze modeling in multi-party dialogues and extraversion expression through gaze aversion control","authors":"Taiken Shintani, Carlos Toshinori Ishi, Hiroshi Ishiguro","doi":"10.1080/01691864.2024.2394538","DOIUrl":"https://doi.org/10.1080/01691864.2024.2394538","url":null,"abstract":"Gaze control plays a crucial role in the context of conversational robots involving multiple participants. Particularly, gaze aversion is not only important for improving human likeness but is also...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"14 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142215898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"VT-VT: a slip detection model for transformer-based visual-tactile fusion","authors":"Jingtao Yang, Mingyou Chen, Weilin Chen, Qinghua Lu, Huiling Wei, Yunzhi Zhang","doi":"10.1080/01691864.2024.2395922","DOIUrl":"https://doi.org/10.1080/01691864.2024.2395922","url":null,"abstract":"Slip detection plays a crucial role in robotic operations and has received increasing attention in the field of robotics. We introduced a slip detection model called VT-VT, based on the fusion of v...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"157 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142215900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Advanced RoboticsPub Date : 2024-09-02DOI: 10.1080/01691864.2024.2393408
Masashi Osada, Gustavo A. Garcia Ricardez, Yosuke Suzuki, Tadahiro Taniguchi
{"title":"Reflectance estimation for proximity sensing by vision-language models: utilizing distributional semantics for low-level cognition in robotics","authors":"Masashi Osada, Gustavo A. Garcia Ricardez, Yosuke Suzuki, Tadahiro Taniguchi","doi":"10.1080/01691864.2024.2393408","DOIUrl":"https://doi.org/10.1080/01691864.2024.2393408","url":null,"abstract":"Large language models (LLMs) and vision-language models (VLMs) have been increasingly used in robotics for high-level cognition, but their use for low-level cognition, such as interpreting sensor i...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"20 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142215795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Advanced RoboticsPub Date : 2024-08-29DOI: 10.1080/01691864.2024.2395926
Laksh Nanwani, Kumaraditya Gupta, Aditya Mathur, Swayam Agrawal, A. H. Abdul Hafez, K. Madhava Krishna
{"title":"Open-set 3D semantic instance maps for vision language navigation – O3D-SIM","authors":"Laksh Nanwani, Kumaraditya Gupta, Aditya Mathur, Swayam Agrawal, A. H. Abdul Hafez, K. Madhava Krishna","doi":"10.1080/01691864.2024.2395926","DOIUrl":"https://doi.org/10.1080/01691864.2024.2395926","url":null,"abstract":"Humans excel at forming mental maps of their surroundings, equipping them to understand object relationships and navigate based on language queries. Our previous work SI Maps (Nanwani L, Agarwal A,...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"22 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142215896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Advanced RoboticsPub Date : 2024-08-22DOI: 10.1080/01691864.2024.2388145
Guillermo Pérez García, Gonzalo A. García, Manuel Castro, Mario Castaño, Marta J. López-González de Quevedo, Ricardo Durán, Luis Pérez, J. Gabriel Amores, Gloria Álvarez, Leigh Michelle Levinson, Selma Šabanović, Levko Ivanchuk, Randy Gomez
{"title":"A multi-site language study on child-robot dialogues","authors":"Guillermo Pérez García, Gonzalo A. García, Manuel Castro, Mario Castaño, Marta J. López-González de Quevedo, Ricardo Durán, Luis Pérez, J. Gabriel Amores, Gloria Álvarez, Leigh Michelle Levinson, Selma Šabanović, Levko Ivanchuk, Randy Gomez","doi":"10.1080/01691864.2024.2388145","DOIUrl":"https://doi.org/10.1080/01691864.2024.2388145","url":null,"abstract":"Child-robot interaction (CRI) has been mostly studied in labs and classroom settings. In this work, we share a CRI language processing study carried out in children's homes, analyzing how each lang...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"64 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142215899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Task and motion planning using mixed integer linear programming for solving fetch-and-carry tasks by a mobile manipulator","authors":"Sotaro Suwa, Keisuke Takeshita, Kimitoshi Yamazaki","doi":"10.1080/01691864.2024.2391831","DOIUrl":"https://doi.org/10.1080/01691864.2024.2391831","url":null,"abstract":"This manuscript describes a TAsk and Motion Planning (TAMP) method for mobile manipulators. We focus on fetch-and-carry tasks, and we aim to simultaneously generate both a sequence of actions and a...","PeriodicalId":7261,"journal":{"name":"Advanced Robotics","volume":"52 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142215925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}